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Items: 1 to 50 of 146

1.

Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment.

Schanstra JP, Luong TT, Makridakis M, Van Linthout S, Lygirou V, Latosinska A, Alesutan I, Boehme B, Schelski N, Von Lewinski D, Mullen W, Nicklin S, Delles C, Feuillet G, Denis C, Lang F, Pieske B, Bascands JL, Mischak H, Saulnier-Blache JS, Voelkl J, Vlahou A, Klein J.

JCI Insight. 2019 May 16;4(10). pii: 125638. doi: 10.1172/jci.insight.125638. eCollection 2019 May 16.

2.

Proteomics based identification of KDM5 histone demethylases associated with cardiovascular disease.

Mokou M, Klein J, Makridakis M, Bitsika V, Bascands JL, Saulnier-Blache JS, Mullen W, Sacherer M, Zoidakis J, Pieske B, Mischak H, Roubelakis MG, Schanstra JP, Vlahou A.

EBioMedicine. 2019 Mar;41:91-104. doi: 10.1016/j.ebiom.2019.02.040. Epub 2019 Feb 28.

3.

Urinary proteome signature of Renal Cysts and Diabetes syndrome in children.

Ricci P, Magalhães P, Krochmal M, Pejchinovski M, Daina E, Caruso MR, Goea L, Belczacka I, Remuzzi G, Umbhauer M, Drube J, Pape L, Mischak H, Decramer S, Schaefer F, Schanstra JP, Cereghini S, Zürbig P.

Sci Rep. 2019 Feb 18;9(1):2225. doi: 10.1038/s41598-019-38713-5.

4.

Implementation of Proteomics Biomarkers in Nephrology: From Animal Models to Human Application?

Klein J, Schanstra JP.

Proteomics Clin Appl. 2019 Mar;13(2):e1800089. doi: 10.1002/prca.201800089. Epub 2018 Nov 12. Review.

PMID:
30334380
5.

The CKD plasma lipidome varies with disease severity and outcome.

Duranton F, Laget J, Gayrard N, Saulnier-Blache JS, Lundin U, Schanstra JP, Mischak H, Weinberger KM, Servel MF, Argilés A.

J Clin Lipidol. 2019 Jan - Feb;13(1):176-185.e8. doi: 10.1016/j.jacl.2018.07.010. Epub 2018 Aug 1.

PMID:
30177483
6.

Prevalence of atheromatous and non-atheromatous cardiovascular disease by age in chronic kidney disease.

Villain C, Metzger M, Combe C, Fouque D, Frimat L, Jacquelinet C, Laville M, Briançon S, Klein J, Schanstra JP, Robinson BM, Mansencal N, Stengel B, Massy ZA; Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) Study Investigators .

Nephrol Dial Transplant. 2018 Aug 28. doi: 10.1093/ndt/gfy277. [Epub ahead of print]

PMID:
30169874
7.

Ldlr-/- and ApoE-/- mice better mimic the human metabolite signature of increased carotid intima media thickness compared to other animal models of cardiovascular disease.

Saulnier-Blache JS, Wilson R, Klavins K, Graham D, Alesutan I, Kastenmüller G, Wang-Sattler R, Adamski J, Roden M, Rathmann W, Seissler J, Meisinger C, Koenig W, Thiery J, Suhre K, Peters A, Kuro-O M, Lang F, Dallmann G, Delles C, Voelkl J, Waldenberger M, Bascands JL, Klein J, Schanstra JP.

Atherosclerosis. 2018 Sep;276:140-147. doi: 10.1016/j.atherosclerosis.2018.07.024. Epub 2018 Jul 21.

PMID:
30059845
8.

Combination of the fetal urinary metabolome and peptidome for the prediction of postnatal renal outcome in fetuses with PUV.

Buffin-Meyer B, Klein J, Breuil B, Muller F, Moulos P, Groussolles M, Bouali O, Bascands JL, Decramer S, Schanstra JP.

J Proteomics. 2018 Jul 30;184:1-9. doi: 10.1016/j.jprot.2018.06.012. Epub 2018 Jun 19.

PMID:
29929039
9.

Epidemiologic observations guiding clinical application of a urinary peptidomic marker of diastolic left ventricular dysfunction.

Zhang ZY, Nkuipou-Kenfack E, Yang WY, Wei FF, Cauwenberghs N, Thijs L, Huang QF, Feng YM, Schanstra JP, Kuznetsova T, Voigt JU, Verhamme P, Mischak H, Staessen JA.

J Am Soc Hypertens. 2018 Jun;12(6):438-447.e4. doi: 10.1016/j.jash.2018.03.007. Epub 2018 Mar 21.

10.

Plasma proteomic analysis reveals altered protein abundances in cardiovascular disease.

Lygirou V, Latosinska A, Makridakis M, Mullen W, Delles C, Schanstra JP, Zoidakis J, Pieske B, Mischak H, Vlahou A.

J Transl Med. 2018 Apr 17;16(1):104. doi: 10.1186/s12967-018-1476-9.

11.

Risk profile, quality of life and care of patients with moderate and advanced CKD: The French CKD-REIN Cohort Study.

Stengel B, Metzger M, Combe C, Jacquelinet C, Briançon S, Ayav C, Fouque D, Laville M, Frimat L, Pascal C, Herpe YE, Morel P, Deleuze JF, Schanstra JP, Lange C, Legrand K, Speyer E, Liabeuf S, Robinson BM, Massy ZA.

Nephrol Dial Transplant. 2019 Feb 1;34(2):277-286. doi: 10.1093/ndt/gfy058.

PMID:
29635335
12.

Comparison of Urine and Plasma Peptidome Indicates Selectivity in Renal Peptide Handling.

Magalhães P, Pontillo C, Pejchinovski M, Siwy J, Krochmal M, Makridakis M, Carrick E, Klein J, Mullen W, Jankowski J, Vlahou A, Mischak H, Schanstra JP, Zürbig P, Pape L.

Proteomics Clin Appl. 2018 Sep;12(5):e1700163. doi: 10.1002/prca.201700163. Epub 2018 Apr 23.

PMID:
29611317
13.

Urinary peptidomics in kidney disease and drug research.

Krochmal M, Schanstra JP, Mischak H.

Expert Opin Drug Discov. 2018 Mar;13(3):259-268. doi: 10.1080/17460441.2018.1418320. Epub 2017 Dec 19. Review.

PMID:
29240457
14.

Association of kidney fibrosis with urinary peptides: a path towards non-invasive liquid biopsies?

Magalhães P, Pejchinovski M, Markoska K, Banasik M, Klinger M, Švec-Billá D, Rychlík I, Rroji M, Restivo A, Capasso G, Bob F, Schiller A, Ortiz A, Perez-Gomez MV, Cannata P, Sanchez-Niño MD, Naumovic R, Brkovic V, Polenakovic M, Mullen W, Vlahou A, Zürbig P, Pape L, Ferrario F, Denis C, Spasovski G, Mischak H, Schanstra JP.

Sci Rep. 2017 Dec 5;7(1):16915. doi: 10.1038/s41598-017-17083-w.

15.

Prediction of Chronic Kidney Disease Stage 3 by CKD273, a Urinary Proteomic Biomarker.

Pontillo C, Zhang ZY, Schanstra JP, Jacobs L, Zürbig P, Thijs L, Ramírez-Torres A, Heerspink HJL, Lindhardt M, Klein R, Orchard T, Porta M, Bilous RW, Charturvedi N, Rossing P, Vlahou A, Schepers E, Glorieux G, Mullen W, Delles C, Verhamme P, Vanholder R, Staessen JA, Mischak H, Jankowski J.

Kidney Int Rep. 2017 Nov;2(6):1066-1075. doi: 10.1016/j.ekir.2017.06.004.

16.

Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy.

Krochmal M, Kontostathi G, Magalhães P, Makridakis M, Klein J, Husi H, Leierer J, Mayer G, Bascands JL, Denis C, Zoidakis J, Zürbig P, Delles C, Schanstra JP, Mischak H, Vlahou A.

Sci Rep. 2017 Nov 9;7(1):15160. doi: 10.1038/s41598-017-15359-9.

17.

Lysophosphatidic Acid Protects Against Endotoxin-Induced Acute Kidney Injury.

Mirzoyan K, Denis C, Casemayou A, Gilet M, Marsal D, Goudounéche D, Faguer S, Bascands JL, Schanstra JP, Saulnier-Blache JS.

Inflammation. 2017 Oct;40(5):1707-1716. doi: 10.1007/s10753-017-0612-7.

PMID:
28667502
18.

Urinary lysophopholipids are increased in diabetic patients with nephropathy.

Saulnier-Blache JS, Feigerlova E, Halimi JM, Gourdy P, Roussel R, Guerci B, Dupuy A, Bertrand-Michel J, Bascands JL, Hadjadj S, Schanstra JP.

J Diabetes Complications. 2017 Jul;31(7):1103-1108. doi: 10.1016/j.jdiacomp.2017.04.024. Epub 2017 May 10.

PMID:
28506691
19.

Increased urine acylcarnitines in diabetic ApoE-/- mice: Hydroxytetradecadienoylcarnitine (C14:2-OH) reflects diabetic nephropathy in a context of hyperlipidemia.

Mirzoyan K, Klavins K, Koal T, Gillet M, Marsal D, Denis C, Klein J, Bascands JL, Schanstra JP, Saulnier-Blache JS.

Biochem Biophys Res Commun. 2017 May 20;487(1):109-115. doi: 10.1016/j.bbrc.2017.04.026. Epub 2017 Apr 7.

PMID:
28396151
20.

Prediction of acute coronary syndromes by urinary proteome analysis.

Htun NM, Magliano DJ, Zhang ZY, Lyons J, Petit T, Nkuipou-Kenfack E, Ramirez-Torres A, von Zur Muhlen C, Maahs D, Schanstra JP, Pontillo C, Pejchinovski M, Snell-Bergeon JK, Delles C, Mischak H, Staessen JA, Shaw JE, Koeck T, Peter K.

PLoS One. 2017 Mar 8;12(3):e0172036. doi: 10.1371/journal.pone.0172036. eCollection 2017.

21.

Systems biology combining human- and animal-data miRNA and mRNA data identifies new targets in ureteropelvic junction obstruction.

Papadopoulos T, Casemayou A, Neau E, Breuil B, Caubet C, Calise D, Thornhill BA, Bachvarova M, Belliere J, Chevalier RL, Moulos P, Bachvarov D, Buffin-Meyer B, Decramer S, Auriol FC, Bascands JL, Schanstra JP, Klein J.

BMC Syst Biol. 2017 Mar 1;11(1):31. doi: 10.1186/s12918-017-0411-7.

22.

The use of urinary proteomics in the assessment of suitability of mouse models for ageing.

Nkuipou-Kenfack E, Schanstra JP, Bajwa S, Pejchinovski M, Vinel C, Dray C, Valet P, Bascands JL, Vlahou A, Koeck T, Borries M, Busch H, Bechtel-Walz W, Huber TB, Rudolph KL, Pich A, Mischak H, Zürbig P.

PLoS One. 2017 Feb 15;12(2):e0166875. doi: 10.1371/journal.pone.0166875. eCollection 2017.

23.

Asymptomatic circulating T-cell clone cause renal polymorphic inflammatory fibrosis.

Ribes D, Casemayou A, El Hachem H, Laurent C, Guilbeau-Frugier C, Vergez F, Tavitian S, Schanstra JP, Chauveau D, Bascands JL, Ysebaert L, Faguer S.

Clin Exp Nephrol. 2017 Oct;21(5):781-786. doi: 10.1007/s10157-016-1373-6. Epub 2016 Dec 26.

PMID:
28018996
24.

Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis.

Siwy J, Zürbig P, Argiles A, Beige J, Haubitz M, Jankowski J, Julian BA, Linde PG, Marx D, Mischak H, Mullen W, Novak J, Ortiz A, Persson F, Pontillo C, Rossing P, Rupprecht H, Schanstra JP, Vlahou A, Vanholder R.

Nephrol Dial Transplant. 2017 Dec 1;32(12):2079-2089. doi: 10.1093/ndt/gfw337.

25.

Comparison of different statistical approaches for urinary peptide biomarker detection in the context of coronary artery disease.

Stanley E, Delatola EI, Nkuipou-Kenfack E, Spooner W, Kolch W, Schanstra JP, Mischak H, Koeck T.

BMC Bioinformatics. 2016 Dec 6;17(1):496.

26.

Urinary biomarkers for renal tract malformations.

Magalhães P, Schanstra JP, Carrick E, Mischak H, Zürbig P.

Expert Rev Proteomics. 2016 Dec;13(12):1121-1129. Epub 2016 Nov 15. Review.

PMID:
27791437
27.

A capillary electrophoresis coupled to mass spectrometry pipeline for long term comparable assessment of the urinary metabolome.

Boizard F, Brunchault V, Moulos P, Breuil B, Klein J, Lounis N, Caubet C, Tellier S, Bascands JL, Decramer S, Schanstra JP, Buffin-Meyer B.

Sci Rep. 2016 Oct 3;6:34453. doi: 10.1038/srep34453.

28.

Increased urinary lysophosphatidic acid in mouse with subtotal nephrectomy: potential involvement in chronic kidney disease.

Mirzoyan K, Baïotto A, Dupuy A, Marsal D, Denis C, Vinel C, Sicard P, Bertrand-Michel J, Bascands JL, Schanstra JP, Klein J, Saulnier-Blache JS.

J Physiol Biochem. 2016 Dec;72(4):803-812. Epub 2016 Sep 17.

PMID:
27637780
29.

Urinary peptidomics provides a noninvasive humanized readout of diabetic nephropathy in mice.

Klein J, Ramirez-Torres A, Ericsson A, Huang Y, Breuil B, Siwy J, Mischak H, Peng XR, Bascands JL, Schanstra JP.

Kidney Int. 2016 Nov;90(5):1045-1055. doi: 10.1016/j.kint.2016.06.023. Epub 2016 Aug 12.

PMID:
27528550
30.

A urinary proteome-based classifier for the early detection of decline in glomerular filtration.

Pontillo C, Jacobs L, Staessen JA, Schanstra JP, Rossing P, Heerspink HJL, Siwy J, Mullen W, Vlahou A, Mischak H, Vanholder R, Zürbig P, Jankowski J.

Nephrol Dial Transplant. 2017 Sep 1;32(9):1510-1516. doi: 10.1093/ndt/gfw239.

PMID:
27387473
31.

Proteomic Analysis of Vitreous Humor in Retinal Vein Occlusion.

Reich M, Dacheva I, Nobl M, Siwy J, Schanstra JP, Mullen W, Koch FH, Kopitz J, Kretz FT, Auffarth GU, Koss MJ.

PLoS One. 2016 Jun 30;11(6):e0158001. doi: 10.1371/journal.pone.0158001. eCollection 2016.

32.

Omics databases on kidney disease: where they can be found and how to benefit from them.

Papadopoulos T, Krochmal M, Cisek K, Fernandes M, Husi H, Stevens R, Bascands JL, Schanstra JP, Klein J.

Clin Kidney J. 2016 Jun;9(3):343-52. doi: 10.1093/ckj/sfv155. Epub 2016 Mar 21. Review.

33.

Epidermal growth factor and kidney disease: a long-lasting story.

Klein J, Bascands JL, Buffin-Meyer B, Schanstra JP.

Kidney Int. 2016 May;89(5):985-987. doi: 10.1016/j.kint.2016.02.020.

PMID:
27083276
34.

[The French Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) cohort study: To better understand chronic kidney disease].

Stengel B, Combe C, Jacquelinet C, Briançon S, Fouque D, Laville M, Frimat L, Pascal C, Herpe YÉ, Morel P, Deleuze JF, Schanstra JP, Pisoni RL, Robinson BM, Massy ZA.

Nephrol Ther. 2016 Apr;12 Suppl 1:S49-56. doi: 10.1016/j.nephro.2016.01.005. Epub 2016 Mar 11. French.

PMID:
26976057
35.

Implementation of CE-MS-identified proteome-based biomarker panels in drug development and patient management.

Stepczynska A, Schanstra JP, Mischak H.

Bioanalysis. 2016;8(5):439-55. doi: 10.4155/bio.16.8. Epub 2016 Feb 19.

PMID:
26891752
36.

The role of urinary peptidomics in kidney disease research.

Klein J, Bascands JL, Mischak H, Schanstra JP.

Kidney Int. 2016 Mar;89(3):539-45. doi: 10.1016/j.kint.2015.10.010. Epub 2016 Jan 14. Review.

PMID:
26880450
37.

Identification of Symptomatic Fetuses Infected with Cytomegalovirus Using Amniotic Fluid Peptide Biomarkers.

Desveaux C, Klein J, Leruez-Ville M, Ramirez-Torres A, Lacroix C, Breuil B, Froment C, Bascands JL, Schanstra JP, Ville Y.

PLoS Pathog. 2016 Jan 25;12(1):e1005395. doi: 10.1371/journal.ppat.1005395. eCollection 2016 Jan.

38.

Urinary Peptide Analysis Differentiates Pancreatic Cancer From Chronic Pancreatitis.

Schönemeier B, Metzger J, Klein J, Husi H, Bremer B, Armbrecht N, Dakna M, Schanstra JP, Rosendahl J, Wiegand J, Jäger M, Mullen W, Breuil B, Plentz RR, Lichtinghagen R, Brand K, Kühnel F, Mischak H, Manns MP, Lankisch TO.

Pancreas. 2016 Aug;45(7):1018-26. doi: 10.1097/MPA.0000000000000573.

PMID:
26784907
39.

Proteomics of vitreous in neovascular age-related macular degeneration.

Nobl M, Reich M, Dacheva I, Siwy J, Mullen W, Schanstra JP, Choi CY, Kopitz J, Kretz FT, Auffarth GU, Koch F, Koss MJ.

Exp Eye Res. 2016 May;146:107-17. doi: 10.1016/j.exer.2016.01.001. Epub 2016 Jan 6.

PMID:
26769219
40.

Calcineurin Inhibitors Downregulate HNF-1β and May Affect the Outcome of HNF1B Patients After Renal Transplantation.

Faguer S, Esposito L, Casemayou A, Pirson Y, Decramer S, Cartery C, Hazzan M, Garrigue V, Roussey G, Cointault O, Ho T, Merville P, Devuyst O, Gourdy P, Chassaing N, Bascands JL, Kamar N, Schanstra JP, Rostaing L, Chauveau D.

Transplantation. 2016 Sep;100(9):1970-8. doi: 10.1097/TP.0000000000000993.

41.

Identification of ageing-associated naturally occurring peptides in human urine.

Nkuipou-Kenfack E, Bhat A, Klein J, Jankowski V, Mullen W, Vlahou A, Dakna M, Koeck T, Schanstra JP, Zürbig P, Rudolph KL, Schumacher B, Pich A, Mischak H.

Oncotarget. 2015 Oct 27;6(33):34106-17. doi: 10.18632/oncotarget.5896.

42.

Unmasking Silent Endothelial Activation in the Cardiovascular System Using Molecular Magnetic Resonance Imaging.

Belliere J, Martinez de Lizarrondo S, Choudhury RP, Quenault A, Le Béhot A, Delage C, Chauveau D, Schanstra JP, Bascands JL, Vivien D, Gauberti M.

Theranostics. 2015 Aug 8;5(11):1187-202. doi: 10.7150/thno.11835. eCollection 2015.

43.

Body fluid peptide and protein signatures in diabetic kidney diseases.

Jankowski J, Schanstra JP, Mischak H.

Nephrol Dial Transplant. 2015 Aug;30 Suppl 4:iv43-53. doi: 10.1093/ndt/gfv091. Review.

PMID:
26209737
44.

New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis.

Glorieux G, Mullen W, Duranton F, Filip S, Gayrard N, Husi H, Schepers E, Neirynck N, Schanstra JP, Jankowski J, Mischak H, Argilés À, Vanholder R, Vlahou A, Klein J.

Nephrol Dial Transplant. 2015 Nov;30(11):1842-52. doi: 10.1093/ndt/gfv254. Epub 2015 Jul 9.

PMID:
26160894
45.

Shear Stress-Induced Alteration of Epithelial Organization in Human Renal Tubular Cells.

Maggiorani D, Dissard R, Belloy M, Saulnier-Blache JS, Casemayou A, Ducasse L, Grès S, Bellière J, Caubet C, Bascands JL, Schanstra JP, Buffin-Meyer B.

PLoS One. 2015 Jul 6;10(7):e0131416. doi: 10.1371/journal.pone.0131416. eCollection 2015.

46.

Kinin B1 receptor antagonism is equally efficient as angiotensin receptor 1 antagonism in reducing renal fibrosis in experimental obstructive nephropathy, but is not additive.

Huart A, Klein J, Gonzalez J, Buffin-Meyer B, Neau E, Delage C, Calise D, Ribes D, Schanstra JP, Bascands JL.

Front Pharmacol. 2015 Feb 2;6:8. doi: 10.3389/fphar.2015.00008. eCollection 2015.

47.

miRNAs in urine: a mirror image of kidney disease?

Papadopoulos T, Belliere J, Bascands JL, Neau E, Klein J, Schanstra JP.

Expert Rev Mol Diagn. 2015 Mar;15(3):361-74. doi: 10.1586/14737159.2015.1009449. Epub 2015 Feb 8. Review.

PMID:
25660955
48.

Diagnosis and Prediction of CKD Progression by Assessment of Urinary Peptides.

Schanstra JP, Zürbig P, Alkhalaf A, Argiles A, Bakker SJ, Beige J, Bilo HJ, Chatzikyrkou C, Dakna M, Dawson J, Delles C, Haller H, Haubitz M, Husi H, Jankowski J, Jerums G, Kleefstra N, Kuznetsova T, Maahs DM, Menne J, Mullen W, Ortiz A, Persson F, Rossing P, Ruggenenti P, Rychlik I, Serra AL, Siwy J, Snell-Bergeon J, Spasovski G, Staessen JA, Vlahou A, Mischak H, Vanholder R.

J Am Soc Nephrol. 2015 Aug;26(8):1999-2010. doi: 10.1681/ASN.2014050423. Epub 2015 Jan 14.

49.

Protein interactome of muscle invasive bladder cancer.

Bhat A, Heinzel A, Mayer B, Perco P, Mühlberger I, Husi H, Merseburger AS, Zoidakis J, Vlahou A, Schanstra JP, Mischak H, Jankowski V.

PLoS One. 2015 Jan 8;10(1):e0116404. doi: 10.1371/journal.pone.0116404. eCollection 2015.

50.

Pretransplant urinary proteome analysis does not predict development of chronic kidney disease after liver transplantation.

Milongo D, Bascands JL, Huart A, Esposito L, Breuil B, Moulos P, Siwy J, Ramírez-Torres A, Ribes D, Lavayssière L, Del Bello A, Muscari F, Alric L, Bureau C, Rostaing L, Schanstra JP, Kamar N.

Liver Int. 2015 Jul;35(7):1893-901. doi: 10.1111/liv.12763. Epub 2015 Jan 20.

PMID:
25515948

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