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Items: 45


A Marfan syndrome human induced pluripotent stem cell line with a heterozygous FBN1 c.4082G>A mutation, ISMMSi002-B, for disease modeling.

Klein S, Dvornik JL, Yarrabothula AR, Schaniel C.

Stem Cell Res. 2017 Aug;23:73-76. doi: 10.1016/j.scr.2017.06.016. Epub 2017 Jul 3.


A human MIXL1 green fluorescent protein reporter embryonic stem cell line engineered using TALEN-based genome editing.

Alexeeva V, D'Souza SL, Schaniel C.

Stem Cell Res. 2016 May 26;17(1):93-96. doi: 10.1016/j.scr.2016.05.010. [Epub ahead of print]


Genomic imprinting defect in Zfp57 mutant iPS cell lines.

McDonald CM, Liu L, Xiao L, Schaniel C, Li X.

Stem Cell Res. 2016 Mar;16(2):259-63. Epub 2016 Jan 21.


Hematopoietic Reprogramming In Vitro Informs In Vivo Identification of Hemogenic Precursors to Definitive Hematopoietic Stem Cells.

Pereira CF, Chang B, Gomes A, Bernitz J, Papatsenko D, Niu X, Swiers G, Azzoni E, de Bruijn MF, Schaniel C, Lemischka IR, Moore KA.

Dev Cell. 2016 Mar 7;36(5):525-39. doi: 10.1016/j.devcel.2016.02.011.


Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN11-Associated Juvenile Myelomonocytic Leukemia.

Mulero-Navarro S, Sevilla A, Roman AC, Lee DF, D'Souza SL, Pardo S, Riess I, Su J, Cohen N, Schaniel C, Rodriguez NA, Baccarini A, Brown BD, Cavé H, Caye A, Strullu M, Yalcin S, Park CY, Dhandapany PS, Yongchao G, Edelmann L, Bahieg S, Raynal P, Flex E, Tartaglia M, Moore KA, Lemischka IR, Gelb BD.

Cell Rep. 2015 Oct 20;13(3):504-515. doi: 10.1016/j.celrep.2015.09.019. Epub 2015 Oct 8.


Distribution Analyzer, a methodology for identifying and clustering outlier conditions from single-cell distributions, and its application to a Nanog reporter RNAi screen.

Gingold JA, Coakley ES, Su J, Lee DF, Lau Z, Zhou H, Felsenfeld DP, Schaniel C, Lemischka IR.

BMC Bioinformatics. 2015 Jul 22;16:225. doi: 10.1186/s12859-015-0636-7.


Tbx3 Controls Dppa3 Levels and Exit from Pluripotency toward Mesoderm.

Waghray A, Saiz N, Jayaprakash AD, Freire AG, Papatsenko D, Pereira CF, Lee DF, Brosh R, Chang B, Darr H, Gingold J, Kelley K, Schaniel C, Hadjantonakis AK, Lemischka IR.

Stem Cell Reports. 2015 Jul 14;5(1):97-110. doi: 10.1016/j.stemcr.2015.05.009. Epub 2015 Jun 18.


Modeling familial cancer with induced pluripotent stem cells.

Lee DF, Su J, Kim HS, Chang B, Papatsenko D, Zhao R, Yuan Y, Gingold J, Xia W, Darr H, Mirzayans R, Hung MC, Schaniel C, Lemischka IR.

Cell. 2015 Apr 9;161(2):240-54. doi: 10.1016/j.cell.2015.02.045.


Biology and mechano-response of tendon cells: Progress overview and perspectives.

Sun HB, Schaniel C, Leong DJ, Wang JH.

J Orthop Res. 2015 Jun;33(6):785-92. doi: 10.1002/jor.22885. Epub 2015 Apr 28. Review.


A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming.

Gingold JA, Fidalgo M, Guallar D, Lau Z, Sun Z, Zhou H, Faiola F, Huang X, Lee DF, Waghray A, Schaniel C, Felsenfeld DP, Lemischka IR, Wang J.

Mol Cell. 2014 Oct 2;56(1):140-52. doi: 10.1016/j.molcel.2014.08.014. Epub 2014 Sep 15.


Epigenetic reprogramming induces the expansion of cord blood stem cells.

Chaurasia P, Gajzer DC, Schaniel C, D'Souza S, Hoffman R.

J Clin Invest. 2014 Jun;124(6):2378-95. doi: 10.1172/JCI70313. Epub 2014 Apr 24.


Divisional history and hematopoietic stem cell function during homeostasis.

Qiu J, Papatsenko D, Niu X, Schaniel C, Moore K.

Stem Cell Reports. 2014 Mar 20;2(4):473-90. doi: 10.1016/j.stemcr.2014.01.016. eCollection 2014 Apr 8.


Induction of a hemogenic program in mouse fibroblasts.

Pereira CF, Chang B, Qiu J, Niu X, Papatsenko D, Hendry CE, Clark NR, Nomura-Kitabayashi A, Kovacic JC, Ma'ayan A, Schaniel C, Lemischka IR, Moore K.

Cell Stem Cell. 2013 Aug 1;13(2):205-18. doi: 10.1016/j.stem.2013.05.024. Epub 2013 Jun 13.


MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency.

Gaspar-Maia A, Qadeer ZA, Hasson D, Ratnakumar K, Leu NA, Leroy G, Liu S, Costanzi C, Valle-Garcia D, Schaniel C, Lemischka I, Garcia B, Pehrson JR, Bernstein E.

Nat Commun. 2013;4:1565. doi: 10.1038/ncomms2582. Erratum in: Nat Commun. 2013;4:2090.


Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming.

Fidalgo M, Faiola F, Pereira CF, Ding J, Saunders A, Gingold J, Schaniel C, Lemischka IR, Silva JC, Wang J.

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16202-7. doi: 10.1073/pnas.1208533109. Epub 2012 Sep 17.


Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling.

Lee DF, Su J, Ang YS, Carvajal-Vergara X, Mulero-Navarro S, Pereira CF, Gingold J, Wang HL, Zhao R, Sevilla A, Darr H, Williamson AJ, Chang B, Niu X, Aguilo F, Flores ER, Sher YP, Hung MC, Whetton AD, Gelb BD, Moore KA, Snoeck HW, Ma'ayan A, Schaniel C, Lemischka IR.

Cell Stem Cell. 2012 Aug 3;11(2):179-94. doi: 10.1016/j.stem.2012.05.020.


Combining competition assays with genetic complementation strategies to dissect mouse embryonic stem cell self-renewal and pluripotency.

Lee DF, Su J, Sevilla A, Gingold J, Schaniel C, Lemischka IR.

Nat Protoc. 2012 Mar 22;7(4):729-48. doi: 10.1038/nprot.2012.018.


Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells.

Schaniel C, Sirabella D, Qiu J, Niu X, Lemischka IR, Moore KA.

Blood. 2011 Sep 1;118(9):2420-9. doi: 10.1182/blood-2010-09-305664. Epub 2011 Jun 7.


Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network.

Ang YS, Tsai SY, Lee DF, Monk J, Su J, Ratnakumar K, Ding J, Ge Y, Darr H, Chang B, Wang J, Rendl M, Bernstein E, Schaniel C, Lemischka IR.

Cell. 2011 Apr 15;145(2):183-97. doi: 10.1016/j.cell.2011.03.003. Epub 2011 Apr 7.


Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells.

Green MD, Chen A, Nostro MC, d'Souza SL, Schaniel C, Lemischka IR, Gouon-Evans V, Keller G, Snoeck HW.

Nat Biotechnol. 2011 Mar;29(3):267-72. doi: 10.1038/nbt.1788. Epub 2011 Feb 27.


Toward a complete in silico, multi-layered embryonic stem cell regulatory network.

Xu H, Schaniel C, Lemischka IR, Ma'ayan A.

Wiley Interdiscip Rev Syst Biol Med. 2010 Nov-Dec;2(6):708-33. doi: 10.1002/wsbm.93. Review.


Exploration of self-renewal and pluripotency in ES cells using RNAi.

Schaniel C, Lee DF, Lemischka IR.

Methods Enzymol. 2010;477:351-65. doi: 10.1016/S0076-6879(10)77018-X.


Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome.

Carvajal-Vergara X, Sevilla A, D'Souza SL, Ang YS, Schaniel C, Lee DF, Yang L, Kaplan AD, Adler ED, Rozov R, Ge Y, Cohen N, Edelmann LJ, Chang B, Waghray A, Su J, Pardo S, Lichtenbelt KD, Tartaglia M, Gelb BD, Lemischka IR.

Nature. 2010 Jun 10;465(7299):808-12. doi: 10.1038/nature09005.


Genetic models to study quiescent stem cells and their niches.

Schaniel C, Moore KA.

Ann N Y Acad Sci. 2009 Sep;1176:26-35. doi: 10.1111/j.1749-6632.2009.04608.x.


Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells.

Schaniel C, Ang YS, Ratnakumar K, Cormier C, James T, Bernstein E, Lemischka IR, Paddison PJ.

Stem Cells. 2009 Dec;27(12):2979-91. doi: 10.1002/stem.223.


Delivery of short hairpin RNAs--triggers of gene silencing--into mouse embryonic stem cells.

Schaniel C, Li F, Schafer XL, Moore T, Lemischka IR, Paddison PJ.

Nat Methods. 2006 May;3(5):397-400. No abstract available.


Stability and plasticity of wild-type and Pax5-deficient precursor B cells.

Rolink AG, Schaniel C, Melchers F.

Immunol Rev. 2002 Sep;187:87-95. Review.


A stem cell molecular signature.

Ivanova NB, Dimos JT, Schaniel C, Hackney JA, Moore KA, Lemischka IR.

Science. 2002 Oct 18;298(5593):601-4. Epub 2002 Sep 12.


Plasticity of Pax-5(-/-) pre-B I cells.

Bruno L, Schaniel C, Rolink A.

Cells Tissues Organs. 2002;171(1):38-43. Review.


In vitro and in vivo plasticity of Pax5-deficient pre-B I cells.

Rolink AG, Schaniel C, Bruno L, Melchers F.

Immunol Lett. 2002 Jun 3;82(1-2):35-40. Review.


A new paradigm for the closed-loop intraoperative administration of analgesics in humans.

Gentilini A, Schaniel C, Morari M, Bieniok C, Wymann R, Schnider T.

IEEE Trans Biomed Eng. 2002 Apr;49(4):289-99.


Multiple hematopoietic cell lineages develop in vivo from transplanted Pax5-deficient pre-B I-cell clones.

Schaniel C, Bruno L, Melchers F, Rolink AG.

Blood. 2002 Jan 15;99(2):472-8.


Chemoattractants MDC and TARC are secreted by malignant B-cell precursors following CD40 ligation and support the migration of leukemia-specific T cells.

Ghia P, Transidico P, Veiga JP, Schaniel C, Sallusto F, Matsushima K, Sallan SE, Rolink AG, Mantovani A, Nadler LM, Cardoso AA.

Blood. 2001 Aug 1;98(3):533-40.


Attractions and migrations of lymphoid cells in the organization of humoral immune responses.

Schaniel C, Rolink AG, Melchers F.

Adv Immunol. 2001;78:111-68. Review. No abstract available.


Selection events operating at various stages in B cell development.

Rolink AG, Schaniel C, Andersson J, Melchers F.

Curr Opin Immunol. 2001 Apr;13(2):202-7. Review.


The cluster of ABCD chemokines which organizes T cell-dependent B cell responses.

Schaniel C, Melchers F, Rolink AG.

Curr Top Microbiol Immunol. 2000;251:181-9. No abstract available.


Fidelity and infidelity in commitment to B-lymphocyte lineage development.

Rolink AG, Schaniel C, Busslinger M, Nutt SL, Melchers F.

Immunol Rev. 2000 Jun;175:104-11. Review.


The role of chemokines in regulating cell migration during humoral immune responses.

Melchers F, Rolink AG, Schaniel C.

Cell. 1999 Nov 12;99(4):351-4. Review. No abstract available.


Four of five RAG-expressing JCkappa-/- small pre-BII cells have no L chain gene rearrangements: detection by high-efficiency single cell PCR.

Yamagami T, ten Boekel E, Schaniel C, Andersson J, Rolink A, Melchers F.

Immunity. 1999 Sep;11(3):309-16.


Three chemokines with potential functions in T lymphocyte-independent and -dependent B lymphocyte stimulation.

Schaniel C, Sallusto F, Ruedl C, Sideras P, Melchers F, Rolink AG.

Eur J Immunol. 1999 Sep;29(9):2934-47.


Human macrophage-derived chemokine (MDC) is strongly expressed following activation of both normal and malignant precursor and mature B cells.

Ghia P, Schaniel C, Rolink AG, Nadler LM, Cardoso AA.

Curr Top Microbiol Immunol. 1999;246:103-10. No abstract available.


A novel CC chemokine ABCD-1, produced by dendritic cells and activated B cells, exclusively attracts activated T lymphocytes.

Schaniel C, Sallusto F, Sideras P, Melchers F, Rolink AG.

Curr Top Microbiol Immunol. 1999;246:95-101. Review. No abstract available.


Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation.

Sallusto F, Schaerli P, Loetscher P, Schaniel C, Lenig D, Mackay CR, Qin S, Lanzavecchia A.

Eur J Immunol. 1998 Sep;28(9):2760-9.


Activated murine B lymphocytes and dendritic cells produce a novel CC chemokine which acts selectively on activated T cells.

Schaniel C, Pardali E, Sallusto F, Speletas M, Ruedl C, Shimizu T, Seidl T, Andersson J, Melchers F, Rolink AG, Sideras P.

J Exp Med. 1998 Aug 3;188(3):451-63.

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