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Items: 1 to 50 of 255

1.

A role for the microbiome in psoriasis?

Schalkwijk J.

Br J Dermatol. 2018 May;178(5):999-1000. doi: 10.1111/bjd.16471. No abstract available.

PMID:
29785812
2.

Immortalized N/TERT keratinocytes as an alternative cell source in 3D human epidermal models.

Smits JPH, Niehues H, Rikken G, van Vlijmen-Willems IMJJ, van de Zande GWHJF, Zeeuwen PLJM, Schalkwijk J, van den Bogaard EH.

Sci Rep. 2017 Sep 19;7(1):11838. doi: 10.1038/s41598-017-12041-y.

3.

A guiding map for inflammation.

Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS, Heneka MT, Hoffman HM, Hotchkiss R, Joosten LAB, Kastner DL, Korte M, Latz E, Libby P, Mandrup-Poulsen T, Mantovani A, Mills KHG, Nowak KL, O'Neill LA, Pickkers P, van der Poll T, Ridker PM, Schalkwijk J, Schwartz DA, Siegmund B, Steer CJ, Tilg H, van der Meer JWM, van de Veerdonk FL, Dinarello CA.

Nat Immunol. 2017 Jul 19;18(8):826-831. doi: 10.1038/ni.3790.

4.

The Effects of Human Beta-Defensins on Skin Cells in vitro.

van Kilsdonk JWJ, Jansen PAM, van den Bogaard EH, Bos C, Bergers M, Zeeuwen PLJM, Schalkwijk J.

Dermatology. 2017;233(2-3):155-163. doi: 10.1159/000477346. Epub 2017 Jul 8.

5.

Psoriasis-Associated Late Cornified Envelope (LCE) Proteins Have Antibacterial Activity.

Niehues H, Tsoi LC, van der Krieken DA, Jansen PAM, Oortveld MAW, Rodijk-Olthuis D, van Vlijmen IMJJ, Hendriks WJAJ, Helder RW, Bouwstra JA, van den Bogaard EH, Stuart PE, Nair RP, Elder JT, Zeeuwen PLJM, Schalkwijk J.

J Invest Dermatol. 2017 Nov;137(11):2380-2388. doi: 10.1016/j.jid.2017.06.003. Epub 2017 Jun 17.

6.

Cathepsin B as a potential cystatin M/E target in the mouse hair follicle.

Oortveld MAW, van Vlijmen-Willems IMJJ, Kersten FFJ, Cheng T, Verdoes M, van Erp PEJ, Verbeek S, Reinheckel T, Hendriks WJAJ, Schalkwijk J, Zeeuwen PLJM.

FASEB J. 2017 Oct;31(10):4286-4294. doi: 10.1096/fj.201700267R. Epub 2017 Jun 8.

7.

Duplicated Enhancer Region Increases Expression of CTSB and Segregates with Keratolytic Winter Erythema in South African and Norwegian Families.

Ngcungcu T, Oti M, Sitek JC, Haukanes BI, Linghu B, Bruccoleri R, Stokowy T, Oakeley EJ, Yang F, Zhu J, Sultan M, Schalkwijk J, van Vlijmen-Willems IMJJ, von der Lippe C, Brunner HG, Ersland KM, Grayson W, Buechmann-Moller S, Sundnes O, Nirmala N, Morgan TM, van Bokhoven H, Steen VM, Hull PR, Szustakowski J, Staedtler F, Zhou H, Fiskerstrand T, Ramsay M.

Am J Hum Genet. 2017 May 4;100(5):737-750. doi: 10.1016/j.ajhg.2017.03.012. Epub 2017 Apr 27.

8.

Keratinocyte Proliferation and Differentiation on IL-9 Stimulation: An Explorative In vitro Study.

Niehues H, Smits JPH, Rodijk-Olthuis D, Schalkwijk J, van den Bogaard EH.

Acta Derm Venereol. 2017 Jun 9;97(6):741-742. doi: 10.2340/00015555-2643. No abstract available.

9.

Reply to Meisel et al.

Zeeuwen PLJM, Boekhorst J, Ederveen THA, Kleerebezem M, Schalkwijk J, van Hijum SAFT, Timmerman HM.

J Invest Dermatol. 2017 Apr;137(4):961-962. doi: 10.1016/j.jid.2016.11.013. Epub 2016 Nov 22. No abstract available.

10.

Recognizing the tenascin-X deficient type of Ehlers-Danlos syndrome: a cross-sectional study in 17 patients.

Demirdas S, Dulfer E, Robert L, Kempers M, van Beek D, Micha D, van Engelen BG, Hamel B, Schalkwijk J, Loeys B, Maugeri A, Voermans NC.

Clin Genet. 2017 Mar;91(3):411-425. doi: 10.1111/cge.12853. Epub 2016 Nov 4.

PMID:
27582382
11.

Spread of Psoriasiform Inflammation to Remote Tissues Is Restricted by the Atypical Chemokine Receptor ACKR2.

Shams K, Wilson GJ, Singh M, van den Bogaard EH, Le Brocq ML, Holmes S, Schalkwijk J, Burden AD, McKimmie CS, Graham GJ.

J Invest Dermatol. 2017 Jan;137(1):85-94. doi: 10.1016/j.jid.2016.07.039. Epub 2016 Aug 26.

12.

Epidermal equivalents of filaggrin null keratinocytes do not show impaired skin barrier function.

Niehues H, Schalkwijk J, van Vlijmen-Willems IMJJ, Rodijk-Olthuis D, van Rossum MM, Wladykowski E, Brandner JM, van den Bogaard EHJ, Zeeuwen PLJM.

J Allergy Clin Immunol. 2017 Jun;139(6):1979-1981.e13. doi: 10.1016/j.jaci.2016.09.016. Epub 2016 Oct 11. No abstract available.

13.

Gram-positive anaerobe cocci are underrepresented in the microbiome of filaggrin-deficient human skin.

Zeeuwen PL, Ederveen TH, van der Krieken DA, Niehues H, Boekhorst J, Kezic S, Hanssen DA, Otero ME, van Vlijmen-Willems IM, Rodijk-Olthuis D, Falcone D, van den Bogaard EH, Kamsteeg M, de Koning HD, Zeeuwen-Franssen ME, van Steensel MA, Kleerebezem M, Timmerman HM, van Hijum SA, Schalkwijk J.

J Allergy Clin Immunol. 2017 Apr;139(4):1368-1371. doi: 10.1016/j.jaci.2016.09.017. Epub 2016 Oct 8. No abstract available.

14.

Polymorphisms in CD84, IL12B and TNFAIP3 are associated with response to biologics in patients with psoriasis.

van den Reek JMPA, Coenen MJH, van de L'Isle Arias M, Zweegers J, Rodijk-Olthuis D, Schalkwijk J, Vermeulen SH, Joosten I, van de Kerkhof PCM, Seyger MMB, Zeeuwen PLJM, de Jong EMGJ.

Br J Dermatol. 2017 May;176(5):1288-1296. doi: 10.1111/bjd.15005. Epub 2017 Apr 10.

PMID:
27564082
15.

Cell Surface Expression of HLA-Cw6 by Human Epidermal Keratinocytes: Positive Regulation by Cytokines, Lack of Correlation to a Variant Upstream of HLA-C.

van den Bogaard EH, Tijssen HJ, Rodijk-Olthuis D, van Houwelingen KP, Coenen MJ, Marget M, Schalkwijk J, Joosten I.

J Invest Dermatol. 2016 Sep;136(9):1903-6. doi: 10.1016/j.jid.2016.05.112. Epub 2016 Jun 11. No abstract available. Erratum in: J Invest Dermatol. 2018 Jun;138(6):1450.

16.

Erythematous nodes, urticarial rash and arthralgias in a large pedigree with NLRC4-related autoinflammatory disease, expansion of the phenotype.

Volker-Touw CM, de Koning HD, Giltay JC, de Kovel CG, van Kempen TS, Oberndorff KM, Boes ML, van Steensel MA, van Well GT, Blokx WA, Schalkwijk J, Simon A, Frenkel J, van Gijn ME.

Br J Dermatol. 2017 Jan;176(1):244-248. doi: 10.1111/bjd.14757. Epub 2016 Dec 8. No abstract available.

PMID:
27203668
17.

Pharmacological Inhibition of Vanin Activity Attenuates Transplant Vasculopathy in Rat Aortic Allografts.

Wedel J, Jansen PA, Botman PN, Rutjes FP, Schalkwijk J, Hillebrands JL.

Transplantation. 2016 Aug;100(8):1656-66. doi: 10.1097/TP.0000000000001169.

PMID:
27014792
18.

An In vitro Model for Bacterial Growth on Human Stratum Corneum.

van der Krieken DA, Ederveen TH, van Hijum SA, Jansen PA, Melchers WJ, Scheepers PT, Schalkwijk J, Zeeuwen PL.

Acta Derm Venereol. 2016 Nov 2;96(7):873-879. doi: 10.2340/00015555-2401.

19.

Genetic and pharmacological inhibition of vanin-1 activity in animal models of type 2 diabetes.

van Diepen JA, Jansen PA, Ballak DB, Hijmans A, Rutjes FP, Tack CJ, Netea MG, Schalkwijk J, Stienstra R.

Sci Rep. 2016 Mar 2;6:21906. doi: 10.1038/srep21906.

20.

Late cornified envelope (LCE) proteins: distinct expression patterns of LCE2 and LCE3 members suggest nonredundant roles in human epidermis and other epithelia.

Niehues H, van Vlijmen-Willems IM, Bergboer JG, Kersten FF, Narita M, Hendriks WJ, van den Bogaard EH, Zeeuwen PL, Schalkwijk J.

Br J Dermatol. 2016 Apr;174(4):795-802. doi: 10.1111/bjd.14284. Epub 2016 Jan 3.

PMID:
26556599
21.

Perfusion Intensity Correlates with Expression Levels of Psoriasis-Related Genes and Proteins.

Hendriks AG, Steenbergen W, Zeeuwen PL, Schalkwijk J, Hondebrink E, Klitsie MA, Schreurs R, van de Kerkhof PC, Seyger MM.

Skin Pharmacol Physiol. 2015;28(6):296-306. doi: 10.1159/000381628. Epub 2015 Sep 12.

PMID:
26361329
22.

Antibiotics in cell culture: friend or foe? Suppression of keratinocyte growth and differentiation in monolayer cultures and 3D skin models.

Nygaard UH, Niehues H, Rikken G, Rodijk-Olthuis D, Schalkwijk J, van den Bogaard EH.

Exp Dermatol. 2015 Dec;24(12):964-5. doi: 10.1111/exd.12834. Epub 2015 Oct 6. No abstract available.

PMID:
26287649
23.

The role of interleukin-1 beta in the pathophysiology of Schnitzler's syndrome.

de Koning HD, Schalkwijk J, Stoffels M, Jongekrijg J, Jacobs JF, Verwiel E, Koenen HJ, Preijers F, Holzinger D, Joosten I, van der Meer JW, Simon A.

Arthritis Res Ther. 2015 Jul 22;17:187. doi: 10.1186/s13075-015-0696-0.

24.

Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation.

Kouwenhoven EN, Oti M, Niehues H, van Heeringen SJ, Schalkwijk J, Stunnenberg HG, van Bokhoven H, Zhou H.

EMBO Rep. 2015 Jul;16(7):863-78. doi: 10.15252/embr.201439941. Epub 2015 Jun 1.

25.

Novel pantothenate derivatives for anti-malarial chemotherapy.

Pett HE, Jansen PA, Hermkens PH, Botman PN, Beuckens-Schortinghuis CA, Blaauw RH, Graumans W, van de Vegte-Bolmer M, Koolen KM, Rutjes FP, Dechering KJ, Sauerwein RW, Schalkwijk J.

Malar J. 2015 Apr 18;14:169. doi: 10.1186/s12936-015-0673-8.

26.

Mast-cell interleukin-1β, neutrophil interleukin-17 and epidermal antimicrobial proteins in the neutrophilic urticarial dermatosis in Schnitzler's syndrome.

de Koning HD, van Vlijmen-Willems IM, Rodijk-Olthuis D, van der Meer JW, Zeeuwen PL, Simon A, Schalkwijk J.

Br J Dermatol. 2015 Aug;173(2):448-56. doi: 10.1111/bjd.13857. Epub 2015 Jul 20.

PMID:
25904179
27.

Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation.

van den Bogaard EH, Podolsky MA, Smits JP, Cui X, John C, Gowda K, Desai D, Amin SG, Schalkwijk J, Perdew GH, Glick AB.

J Invest Dermatol. 2015 May;135(5):1320-1328. doi: 10.1038/jid.2015.6. Epub 2015 Jan 20.

28.

A thioesterase bypasses the requirement for exogenous fatty acids in the plsX deletion of Streptococcus pneumoniae.

Parsons JB, Frank MW, Eleveld MJ, Schalkwijk J, Broussard TC, de Jonge MI, Rock CO.

Mol Microbiol. 2015 Apr;96(1):28-41. doi: 10.1111/mmi.12916. Epub 2015 Jan 30.

29.

Absent in Melanoma 2 is predominantly present in primary melanoma and primary squamous cell carcinoma, but largely absent in metastases of both tumors.

de Koning HD, van Vlijmen-Willems IM, Zeeuwen PL, Blokx WA, Schalkwijk J.

J Am Acad Dermatol. 2014 Nov;71(5):1012-5. doi: 10.1016/j.jaad.2014.06.012. Epub 2014 Oct 15. No abstract available.

PMID:
25437966
30.

Myeloid lineage-restricted somatic mosaicism of NLRP3 mutations in patients with variant Schnitzler syndrome.

de Koning HD, van Gijn ME, Stoffels M, Jongekrijg J, Zeeuwen PL, Elferink MG, Nijman IJ, Jansen PA, Neveling K, van der Meer JW, Schalkwijk J, Simon A.

J Allergy Clin Immunol. 2015 Feb;135(2):561-4. doi: 10.1016/j.jaci.2014.07.050. Epub 2014 Sep 16. No abstract available.

PMID:
25239704
31.

Chemical biology tools to study pantetheinases of the vanin family.

Schalkwijk J, Jansen P.

Biochem Soc Trans. 2014 Aug;42(4):1052-5. doi: 10.1042/BST20140074. Review.

PMID:
25110001
32.

Analysis of protein-protein interaction between late cornified envelope proteins and corneodesmosin.

Bergboer JG, Dulak MG, van Vlijmen-Willems IM, Jonca N, van Wijk E, Hendriks WJ, Zeeuwen PL, Schalkwijk J.

Exp Dermatol. 2014 Oct;23(10):769-71. doi: 10.1111/exd.12524.

PMID:
25078048
33.

Immune responses to stress in rheumatoid arthritis and psoriasis.

de Brouwer SJ, van Middendorp H, Stormink C, Kraaimaat FW, Joosten I, Radstake TR, de Jong EM, Schalkwijk J, Donders AR, Eijsbouts A, van de Kerkhof PC, van Riel PL, Evers AW.

Rheumatology (Oxford). 2014 Oct;53(10):1844-8. doi: 10.1093/rheumatology/keu221. Epub 2014 May 20.

PMID:
24850878
34.

Genotype-phenotype correlations in a prospective cohort study of paediatric plaque psoriasis: lack of correlation between HLA-C*06 and family history of psoriasis.

Oostveen AM, Bergboer JG, van de Kerkhof PC, Zeeuwen PL, de Jong EM, Schalkwijk J, Seyger MM.

Acta Derm Venereol. 2014 Nov;94(6):667-71. doi: 10.2340/00015555-1810.

35.

PPAR-alpha dependent regulation of vanin-1 mediates hepatic lipid metabolism.

van Diepen JA, Jansen PA, Ballak DB, Hijmans A, Hooiveld GJ, Rommelaere S, Galland F, Naquet P, Rutjes FP, Mensink RP, Schrauwen P, Tack CJ, Netea MG, Kersten S, Schalkwijk J, Stienstra R.

J Hepatol. 2014 Aug;61(2):366-72. doi: 10.1016/j.jhep.2014.04.013. Epub 2014 Apr 18.

PMID:
24751833
36.

The psychophysiological stress response in psoriasis and rheumatoid arthritis.

de Brouwer SJ, van Middendorp H, Stormink C, Kraaimaat FW, Sweep FC, de Jong EM, Schalkwijk J, Eijsbouts A, Donders AR, van de Kerkhof PC, van Riel PL, Evers AW.

Br J Dermatol. 2014 Apr;170(4):824-31. doi: 10.1111/bjd.12697.

PMID:
24641720
37.

The effect of adalimumab on key drivers in the pathogenesis of psoriasis.

Hendriks AG, van der Velden HM, Wolberink EA, Seyger MM, Schalkwijk J, Zeeuwen PL, de Jong EM, Pasch MC, van Erp PE, van de Kerkhof PC.

Br J Dermatol. 2014 Mar;170(3):571-80. doi: 10.1111/bjd.12705.

PMID:
24640989
38.

Crosstalk between keratinocytes and T cells in a 3D microenvironment: a model to study inflammatory skin diseases.

van den Bogaard EH, Tjabringa GS, Joosten I, Vonk-Bergers M, van Rijssen E, Tijssen HJ, Erkens M, Schalkwijk J, Koenen HJPM.

J Invest Dermatol. 2014 Mar;134(3):719-727. doi: 10.1038/jid.2013.417. Epub 2013 Oct 11.

39.

Microbiome and skin diseases.

Zeeuwen PL, Kleerebezem M, Timmerman HM, Schalkwijk J.

Curr Opin Allergy Clin Immunol. 2013 Oct;13(5):514-20. doi: 10.1097/ACI.0b013e328364ebeb. Review.

PMID:
23974680
40.

An in vitro wound healing model for evaluation of dermal substitutes.

van Kilsdonk JW, van den Bogaard EH, Jansen PA, Bos C, Bergers M, Schalkwijk J.

Wound Repair Regen. 2013 Nov-Dec;21(6):890-6. doi: 10.1111/wrr.12086. Epub 2013 Aug 12.

PMID:
23937125
41.

Combination of pantothenamides with vanin inhibitors as a novel antibiotic strategy against gram-positive bacteria.

Jansen PA, Hermkens PH, Zeeuwen PL, Botman PN, Blaauw RH, Burghout P, van Galen PM, Mouton JW, Rutjes FP, Schalkwijk J.

Antimicrob Agents Chemother. 2013 Oct;57(10):4794-800. doi: 10.1128/AAC.00603-13. Epub 2013 Jul 22.

42.

Skin microbiome imbalance in patients with STAT1/STAT3 defects impairs innate host defense responses.

Smeekens SP, Huttenhower C, Riza A, van de Veerdonk FL, Zeeuwen PL, Schalkwijk J, van der Meer JW, Xavier RJ, Netea MG, Gevers D.

J Innate Immun. 2014;6(3):253-62. doi: 10.1159/000351912. Epub 2013 Jun 22.

43.

Identifying targets for topical RNAi therapeutics in psoriasis: assessment of a new in vitro psoriasis model.

Bracke S, Desmet E, Guerrero-Aspizua S, Tjabringa SG, Schalkwijk J, Van Gele M, Carretero M, Lambert J.

Arch Dermatol Res. 2013 Aug;305(6):501-12. doi: 10.1007/s00403-013-1379-9. Epub 2013 Jun 18.

PMID:
23775225
44.

Compound heterozygous mutations of the TNXB gene cause primary myopathy.

Pénisson-Besnier I, Allamand V, Beurrier P, Martin L, Schalkwijk J, van Vlijmen-Willems I, Gartioux C, Malfait F, Syx D, Macchi L, Marcorelles P, Arbeille B, Croué A, De Paepe A, Dubas F.

Neuromuscul Disord. 2013 Aug;23(8):664-9. doi: 10.1016/j.nmd.2013.04.009. Epub 2013 Jun 12.

PMID:
23768946
45.

APR-246/PRIMA-1(MET) rescues epidermal differentiation in skin keratinocytes derived from EEC syndrome patients with p63 mutations.

Shen J, van den Bogaard EH, Kouwenhoven EN, Bykov VJ, Rinne T, Zhang Q, Tjabringa GS, Gilissen C, van Heeringen SJ, Schalkwijk J, van Bokhoven H, Wiman KG, Zhou H.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2157-62. doi: 10.1073/pnas.1201993110. Epub 2013 Jan 25.

46.

Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis.

van den Bogaard EH, Bergboer JG, Vonk-Bergers M, van Vlijmen-Willems IM, Hato SV, van der Valk PG, Schröder JM, Joosten I, Zeeuwen PL, Schalkwijk J.

J Clin Invest. 2013 Feb;123(2):917-27. doi: 10.1172/JCI65642. Epub 2013 Jan 25.

47.

Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease.

Jansen PA, van Diepen JA, Ritzen B, Zeeuwen PL, Cacciatore I, Cornacchia C, van Vlijmen-Willems IM, de Heuvel E, Botman PN, Blaauw RH, Hermkens PH, Rutjes FP, Schalkwijk J.

ACS Chem Biol. 2013 Mar 15;8(3):530-4. doi: 10.1021/cb3006424. Epub 2013 Jan 2.

PMID:
23270378
48.

Strong induction of AIM2 expression in human epidermis in acute and chronic inflammatory skin conditions.

de Koning HD, Bergboer JG, van den Bogaard EH, van Vlijmen-Willems IM, Rodijk-Olthuis D, Simon A, Zeeuwen PL, Schalkwijk J.

Exp Dermatol. 2012 Dec;21(12):961-4. doi: 10.1111/exd.12037.

PMID:
23171461
49.

Cystatin M/E knockdown by lentiviral delivery of shRNA impairs epidermal morphogenesis of human skin equivalents.

Jansen PA, van den Bogaard EH, Kersten FF, Oostendorp C, van Vlijmen-Willems IM, Oji V, Traupe H, Hennies HC, Schalkwijk J, Zeeuwen PL.

Exp Dermatol. 2012 Nov;21(11):889-91. doi: 10.1111/exd.12022.

PMID:
23163660
50.

Microbiome dynamics of human epidermis following skin barrier disruption.

Zeeuwen PL, Boekhorst J, van den Bogaard EH, de Koning HD, van de Kerkhof PM, Saulnier DM, van Swam II, van Hijum SA, Kleerebezem M, Schalkwijk J, Timmerman HM.

Genome Biol. 2012 Nov 15;13(11):R101. doi: 10.1186/gb-2012-13-11-r101.

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