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Items: 11

1.

Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a "Tail Switching" Strategy on a Piperazinyl Azetidine Skeleton.

Chen Z, Mori W, Deng X, Cheng R, Ogasawara D, Zhang G, Schafroth MA, Dahl K, Fu H, Hatori A, Shao T, Zhang Y, Yamasaki T, Zhang X, Rong J, Yu Q, Hu K, Fujinaga M, Xie L, Kumata K, Gou Y, Chen J, Gu S, Bao L, Wang L, Collier TL, Vasdev N, Shao Y, Ma JA, Cravatt BF, Fowler C, Josephson L, Zhang MR, Liang SH.

J Med Chem. 2019 Apr 11;62(7):3336-3353. doi: 10.1021/acs.jmedchem.8b01778. Epub 2019 Mar 21.

PMID:
30829483
2.

Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high.

Chicca A, Schafroth MA, Reynoso-Moreno I, Erni R, Petrucci V, Carreira EM, Gertsch J.

Sci Adv. 2018 Oct 24;4(10):eaat2166. doi: 10.1126/sciadv.aat2166. eCollection 2018 Oct.

3.

HATRIC-based identification of receptors for orphan ligands.

Sobotzki N, Schafroth MA, Rudnicka A, Koetemann A, Marty F, Goetze S, Yamauchi Y, Carreira EM, Wollscheid B.

Nat Commun. 2018 Apr 17;9(1):1519. doi: 10.1038/s41467-018-03936-z.

4.

Synthesis of Photoswitchable Δ9-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling.

Westphal MV, Schafroth MA, Sarott RC, Imhof MA, Bold CP, Leippe P, Dhopeshwarkar A, Grandner JM, Katritch V, Mackie K, Trauner D, Carreira EM, Frank JA.

J Am Chem Soc. 2017 Dec 20;139(50):18206-18212. doi: 10.1021/jacs.7b06456. Epub 2017 Dec 12.

PMID:
29161035
5.

Enantioselective Iridium-Catalyzed Allylic Cyclizations.

Schafroth MA, Rummelt SM, Sarlah D, Carreira EM.

Org Lett. 2017 Jun 16;19(12):3235-3238. doi: 10.1021/acs.orglett.7b01346. Epub 2017 Jun 2.

PMID:
28573860
6.

Synthesis of Phytocannabinoids.

Schafroth MA, Carreira EM.

Prog Chem Org Nat Prod. 2017;103:37-59. doi: 10.1007/978-3-319-45541-9_2. Review.

PMID:
28120230
7.

Stereodivergent total synthesis of Δ9-tetrahydrocannabinols.

Schafroth MA, Zuccarello G, Krautwald S, Sarlah D, Carreira EM.

Angew Chem Int Ed Engl. 2014 Dec 8;53(50):13898-901. doi: 10.1002/anie.201408380. Epub 2014 Oct 10.

PMID:
25303495
8.

Amine-selective bioconjugation using arene diazonium salts.

Diethelm S, Schafroth MA, Carreira EM.

Org Lett. 2014 Aug 1;16(15):3908-11. doi: 10.1021/ol5016509. Epub 2014 Jul 14.

PMID:
25019948
9.

Stereodivergent α-allylation of linear aldehydes with dual iridium and amine catalysis.

Krautwald S, Schafroth MA, Sarlah D, Carreira EM.

J Am Chem Soc. 2014 Feb 26;136(8):3020-3. doi: 10.1021/ja5003247. Epub 2014 Feb 13.

PMID:
24506196
10.

Enantio- and diastereodivergent dual catalysis: α-allylation of branched aldehydes.

Krautwald S, Sarlah D, Schafroth MA, Carreira EM.

Science. 2013 May 31;340(6136):1065-8. doi: 10.1126/science.1237068.

11.

Iridium-catalyzed enantioselective polyene cyclization.

Schafroth MA, Sarlah D, Krautwald S, Carreira EM.

J Am Chem Soc. 2012 Dec 19;134(50):20276-8. doi: 10.1021/ja310386m. Epub 2012 Dec 11.

PMID:
23193947

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