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Items: 12


Potential mechanisms linking SIRT activity and hypoxic 2-hydroxyglutarate generation: no role for direct enzyme (de)acetylation.

Nadtochiy SM, Wang YT, Zhang J, Nehrke K, Schafer X, Welle K, Ghaemmaghami S, Munger J, Brookes PS.

Biochem J. 2017 Aug 10;474(16):2829-2839. doi: 10.1042/BCJ20170389.


Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells.

Smith B, Schafer XL, Ambeskovic A, Spencer CM, Land H, Munger J.

Cell Rep. 2016 Oct 11;17(3):821-836. doi: 10.1016/j.celrep.2016.09.045.


Acidic pH Is a Metabolic Switch for 2-Hydroxyglutarate Generation and Signaling.

Nadtochiy SM, Schafer X, Fu D, Nehrke K, Munger J, Brookes PS.

J Biol Chem. 2016 Sep 16;291(38):20188-97. doi: 10.1074/jbc.M116.738799. Epub 2016 Aug 10.


Expression of Oncogenic Alleles Induces Multiple Blocks to Human Cytomegalovirus Infection.

Xu S, Schafer X, Munger J.

J Virol. 2016 Apr 14;90(9):4346-4356. doi: 10.1128/JVI.00179-16. Print 2016 May.


Metabolomic profiling of the heart during acute ischemic preconditioning reveals a role for SIRT1 in rapid cardioprotective metabolic adaptation.

Nadtochiy SM, Urciuoli W, Zhang J, Schafer X, Munger J, Brookes PS.

J Mol Cell Cardiol. 2015 Nov;88:64-72. doi: 10.1016/j.yjmcc.2015.09.008. Epub 2015 Sep 24.


The human cytomegalovirus UL26 protein antagonizes NF-κB activation.

Mathers C, Schafer X, Martínez-Sobrido L, Munger J.

J Virol. 2014 Dec;88(24):14289-300. doi: 10.1128/JVI.02552-14. Epub 2014 Oct 1.


Human cytomegalovirus induces the activity and expression of acetyl-coenzyme A carboxylase, a fatty acid biosynthetic enzyme whose inhibition attenuates viral replication.

Spencer CM, Schafer XL, Moorman NJ, Munger J.

J Virol. 2011 Jun;85(12):5814-24. doi: 10.1128/JVI.02630-10. Epub 2011 Apr 6.


Inhibition of calmodulin-dependent kinase kinase blocks human cytomegalovirus-induced glycolytic activation and severely attenuates production of viral progeny.

McArdle J, Schafer XL, Munger J.

J Virol. 2011 Jan;85(2):705-14. doi: 10.1128/JVI.01557-10. Epub 2010 Nov 17. Erratum in: J Virol. 2013 Jun;87(12):7197.


A combinatorial code for pattern formation in Drosophila oogenesis.

Yakoby N, Bristow CA, Gong D, Schafer X, Lembong J, Zartman JJ, Halfon MS, Schüpbach T, Shvartsman SY.

Dev Cell. 2008 Nov;15(5):725-37. doi: 10.1016/j.devcel.2008.09.008.


Expression patterns of cadherin genes in Drosophila oogenesis.

Zartman JJ, Kanodia JS, Yakoby N, Schafer X, Watson C, Schlichting K, Dahmann C, Shvartsman SY.

Gene Expr Patterns. 2009 Jan;9(1):31-6. doi: 10.1016/j.gep.2008.09.001. Epub 2008 Sep 11.


Dissecting self-renewal in stem cells with RNA interference.

Ivanova N, Dobrin R, Lu R, Kotenko I, Levorse J, DeCoste C, Schafer X, Lun Y, Lemischka IR.

Nature. 2006 Aug 3;442(7102):533-8. Epub 2006 Jun 11.


Delivery of short hairpin RNAs--triggers of gene silencing--into mouse embryonic stem cells.

Schaniel C, Li F, Schafer XL, Moore T, Lemischka IR, Paddison PJ.

Nat Methods. 2006 May;3(5):397-400. No abstract available.


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