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Items: 47


Author Correction: LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells.

Lim SY, Macheleidt I, Dalvi P, Schäfer SC, Kerick M, Ozretić L, Ortiz-Cuaran S, George J, Merkelbach-Bruse S, Wolf J, Timmermann B, Thomas RK, Schweiger MR, Buettner R, Odenthal M.

Sci Rep. 2018 Nov 1;8(1):16452. doi: 10.1038/s41598-018-31451-0.


Preclinical studies reveal that LSD1 inhibition results in tumor growth arrest in lung adenocarcinoma independently of driver mutations.

Macheleidt IF, Dalvi PS, Lim SY, Meemboor S, Meder L, Käsgen O, Müller M, Kleemann K, Wang L, Nürnberg P, Rüsseler V, Schäfer SC, Mahabir E, Büttner R, Odenthal M.

Mol Oncol. 2018 Nov;12(11):1965-1979. doi: 10.1002/1878-0261.12382. Epub 2018 Oct 13.


Current PD-L1 immunohistochemistry for non-small cell lung cancer.

Scheel AH, Schäfer SC.

J Thorac Dis. 2018 Mar;10(3):1217-1219. doi: 10.21037/jtd.2018.02.38. No abstract available.


Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia.

Herling CD, Abedpour N, Weiss J, Schmitt A, Jachimowicz RD, Merkel O, Cartolano M, Oberbeck S, Mayer P, Berg V, Thomalla D, Kutsch N, Stiefelhagen M, Cramer P, Wendtner CM, Persigehl T, Saleh A, Altmüller J, Nürnberg P, Pallasch C, Achter V, Lang U, Eichhorst B, Castiglione R, Schäfer SC, Büttner R, Kreuzer KA, Reinhardt HC, Hallek M, Frenzel LP, Peifer M.

Nat Commun. 2018 Feb 20;9(1):727. doi: 10.1038/s41467-018-03170-7.


LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells.

Lim SY, Macheleidt I, Dalvi P, Schäfer SC, Kerick M, Ozretić L, Ortiz-Cuaran S, George J, Merkelbach-Bruse S, Wolf J, Timmermann B, Thomas RK, Schweiger MR, Buettner R, Odenthal M.

Sci Rep. 2017 Aug 31;7(1):10292. doi: 10.1038/s41598-017-09554-x. Erratum in: Sci Rep. 2018 Nov 1;8(1):16452.


Comparison of Blood Collection Tubes from Three Different Manufacturers for the Collection of Cell-Free DNA for Liquid Biopsy Mutation Testing.

Alidousty C, Brandes D, Heydt C, Wagener S, Wittersheim M, Schäfer SC, Holz B, Merkelbach-Bruse S, Büttner R, Fassunke J, Schultheis AM.

J Mol Diagn. 2017 Sep;19(5):801-804. doi: 10.1016/j.jmoldx.2017.06.004. Epub 2017 Jul 18.


First case report of a curative wedge resection in epithelial-myoepithelial carcinoma of the lung.

Hagmeyer L, Tharun L, Schäfer SC, Hekmat K, Büttner R, Randerath W.

Gen Thorac Cardiovasc Surg. 2017 Sep;65(9):535-538. doi: 10.1007/s11748-017-0796-7. Epub 2017 Jun 26.


miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers.

Langsch S, Baumgartner U, Haemmig S, Schlup C, Schäfer SC, Berezowska S, Rieger G, Dorn P, Tschan MP, Vassella E.

Cancer Res. 2016 Jul 15;76(14):4160-9. doi: 10.1158/0008-5472.CAN-15-2580. Epub 2016 May 19. Erratum in: Cancer Res. 2016 Nov 1;76(21):6436.


B-cell-specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice.

Knittel G, Liedgens P, Korovkina D, Seeger JM, Al-Baldawi Y, Al-Maarri M, Fritz C, Vlantis K, Bezhanova S, Scheel AH, Wolz OO, Reimann M, Möller P, López C, Schlesner M, Lohneis P, Weber AN, Trümper L; German International Cancer Genome Consortium Molecular Mechanisms in Malignant Lymphoma by Sequencing Project Consortium, Staudt LM, Ortmann M, Pasparakis M, Siebert R, Schmitt CA, Klatt AR, Wunderlich FT, Schäfer SC, Persigehl T, Montesinos-Rongen M, Odenthal M, Büttner R, Frenzel LP, Kashkar H, Reinhardt HC.

Blood. 2016 Jun 2;127(22):2732-41. doi: 10.1182/blood-2015-11-684183. Epub 2016 Apr 5.


Molecular profiling of lung adenosquamous carcinoma: hybrid or genuine type?

Vassella E, Langsch S, Dettmer MS, Schlup C, Neuenschwander M, Frattini M, Gugger M, Schäfer SC.

Oncotarget. 2015 Sep 15;6(27):23905-16.


Bolstering Components of the Immune Response Compromised by Prior Exposure to Adenovirus: Guided Formulation Development for a Nasal Ebola Vaccine.

Choi JH, Schafer SC, Freiberg AN, Croyle MA.

Mol Pharm. 2015 Aug 3;12(8):2697-711. doi: 10.1021/mp5006454. Epub 2015 Jan 20.


Reactivated Moraxella osteitis presenting as granulomatous disease.

Sendi P, Meier R, Sonderegger B, Bonel HM, Schäfer SC, Vögelin E.

Neth J Med. 2014 Nov;72(9):491-3.


A Single Dose Respiratory Recombinant Adenovirus-Based Vaccine Provides Long-Term Protection for Non-Human Primates from Lethal Ebola Infection.

Choi JH, Jonsson-Schmunk K, Qiu X, Shedlock DJ, Strong J, Xu JX, Michie KL, Audet J, Fernando L, Myers MJ, Weiner D, Bajrovic I, Tran LQ, Wong G, Bello A, Kobinger GP, Schafer SC, Croyle MA.

Mol Pharm. 2015 Aug 3;12(8):2712-31. doi: 10.1021/mp500646d. Epub 2014 Nov 14.


[Therapy-resistant pneumonia].

Oestmann A, Schäfer SC, Geiser T.

Praxis (Bern 1994). 2014 Oct 15;103(21):1271-4. doi: 10.1024/1661-8157/a001804. German.


Automatic cell segmentation in strongly agglomerated cell networks for different cell types.

Buhl S, Neumann B, Schäfer SC, Severing AL.

Int J Comput Biol Drug Des. 2014;7(2-3):259-77. doi: 10.1504/IJCBDD.2014.061641. Epub 2014 May 28.


A retroperitoneal bronchogenic cyst mimicking a pancreatic or adrenal mass.

Runge T, Blank A, Schäfer SC, Candinas D, Gloor B, Angst E.

Case Rep Gastroenterol. 2013 Oct 5;7(3):428-32. doi: 10.1159/000355879. eCollection 2013.


Modeling pre-existing immunity to adenovirus in rodents: immunological requirements for successful development of a recombinant adenovirus serotype 5-based ebola vaccine.

Choi JH, Schafer SC, Zhang L, Juelich T, Freiberg AN, Croyle MA.

Mol Pharm. 2013 Sep 3;10(9):3342-55. doi: 10.1021/mp4001316. Epub 2013 Aug 19.


Cytokeratin-positive epithelioid gastrointestinal stromal tumor of the stomach - a comment on "gastric undifferentiated carcinoma with diffuse c-kit overexpression and focal neuroendocrine differentiation".

Hewer E, Genitsch V, Schäfer SC, Vajtai I.

Pathol Res Pract. 2013 Jul;209(7):467-8. doi: 10.1016/j.prp.2013.04.015. Epub 2013 May 9. No abstract available.


Myoepithelioma of the cerebellopontine angle: a previously not documented benign salivary gland-type neoplasm within the cranium.

Vajtai I, Hewer E, Neuenschwander M, Schäfer SC, Kappeler A, Lukes A.

Clin Neuropathol. 2013 May-Jun;32(3):176-82. doi: 10.5414/NP300596.


Rosette-forming glioneuronal tumor of the cerebellum in statu nascendi: an incidentally detected diminutive example indicates derivation from the internal granule cell layer.

Thommen F, Hewer E, Schäfer SC, Vassella E, Kappeler A, Vajtai I.

Clin Neuropathol. 2013 Sep-Oct;32(5):370-6. doi: 10.5414/NP300612.


RNA interference screening identifies a novel role for autocrine fibroblast growth factor signaling in neuroblastoma chemoresistance.

Salm F, Cwiek P, Ghosal A, Lucia Buccarello A, Largey F, Wotzkow C, Höland K, Styp-Rekowska B, Djonov V, Zlobec I, Bodmer N, Gross N, Westermann F, Schäfer SC, Arcaro A.

Oncogene. 2013 Aug 22;32(34):3944-53. doi: 10.1038/onc.2012.416. Epub 2012 Oct 1.


Intravital microscopy reveals endothelial dysfunction in resistance arterioles in Angiotensin II-induced hypertension.

Schäfer SC, Pellegrin M, Wyss C, Aubert JF, Nussberger J, Hayoz D, Lehr HA, Mazzolai L.

Hypertens Res. 2012 Aug;35(8):855-61. doi: 10.1038/hr.2012.58. Epub 2012 May 10.


Impact of salt on cardiac differential gene expression and coronary lesion in normotensive mineralocorticoid-treated mice.

Wang Q, Domenighetti AA, Schäfer SC, Weber J, Simon A, Maillard MP, Pedrazzini T, Chen J, Lehr HA, Burnier M.

Am J Physiol Regul Integr Comp Physiol. 2012 May;302(9):R1025-33. doi: 10.1152/ajpregu.00387.2011. Epub 2012 Mar 7.


Photodynamic drug delivery enhancement in tumours does not depend on leukocyte-endothelial interaction in a human mesothelioma xenograft model.

Wang Y, Perentes JY, Schäfer SC, Gonzalez M, Debefve E, Lehr HA, van den Bergh H, Krueger T.

Eur J Cardiothorac Surg. 2012 Aug;42(2):348-54. doi: 10.1093/ejcts/ezr294. Epub 2012 Jan 27.


A single sublingual dose of an adenovirus-based vaccine protects against lethal Ebola challenge in mice and guinea pigs.

Choi JH, Schafer SC, Zhang L, Kobinger GP, Juelich T, Freiberg AN, Croyle MA.

Mol Pharm. 2012 Jan 1;9(1):156-67. doi: 10.1021/mp200392g. Epub 2011 Dec 15.


Optimized adenovirus-antibody complexes stimulate strong cellular and humoral immune responses against an encoded antigen in naive mice and those with preexisting immunity.

Choi JH, Dekker J, Schafer SC, John J, Whitfill CE, Petty CS, Haddad EE, Croyle MA.

Clin Vaccine Immunol. 2012 Jan;19(1):84-95. doi: 10.1128/CVI.05319-11. Epub 2011 Nov 16.


Inflammatory myofibroblastic tumor of the trachea with concomitant granulomatous lymph node lesions.

Koch JA, Dorn P, Rausch T, Ris HB, Lehr HA, Schäfer SC.

Case Rep Med. 2011;2011:151729. doi: 10.1155/2011/151729. Epub 2011 Sep 13.


Early occurrence of lung adenocarcinoma and breast cancer after radiotherapy of a chest wall sarcoma in a patient with a de novo germline mutation in TP53.

Ferrarini A, Auteri-Kaczmarek A, Pica A, Boesch N, Heinimann K, Schäfer SC, Vesnaver-Megalo S, Cina V, Beckmann JS, Monnerat C.

Fam Cancer. 2011 Jun;10(2):187-92. doi: 10.1007/s10689-010-9415-9. Review.


Cryopreservation of prostate cancer tissue during routine processing of fresh unfixed prostatectomy specimen: demonstration and validation of a new technique.

Schäfer SC, Pfnür M, Yerly S, Fandel TM, Jichlinski P, Lehr HA.

Prostate. 2009 Feb 1;69(2):191-7. doi: 10.1002/pros.20868.


Do we truly see what we think we see? The role of cognitive bias in pathological interpretation.

Fandel TM, Pfnür M, Schäfer SC, Bacchetti P, Mast FW, Corinth C, Ansorge M, Melchior SW, Thüroff JW, Kirkpatrick CJ, Lehr HA.

J Pathol. 2008 Oct;216(2):193-200. doi: 10.1002/path.2395.


The heart communicates with the endothelium through the guanylyl cyclase-A receptor: acute handling of intravascular volume in response to volume expansion.

Schreier B, Börner S, Völker K, Gambaryan S, Schäfer SC, Kuhlencordt P, Gassner B, Kuhn M.

Endocrinology. 2008 Aug;149(8):4193-9. doi: 10.1210/en.2008-0212. Epub 2008 May 1.


Expression of multiple epigenetically regulated cancer/germline genes in nonsmall cell lung cancer.

Grunwald C, Koslowski M, Arsiray T, Dhaene K, Praet M, Victor A, Morresi-Hauf A, Lindner M, Passlick B, Lehr HA, Schäfer SC, Seitz G, Huber C, Sahin U, Türeci O.

Int J Cancer. 2006 May 15;118(10):2522-8.


Paradoxical attenuation of leukocyte rolling in response to ischemia- reperfusion and extracorporeal blood circulation in inflamed tissue.

Schäfer SC, Sehrt DN, Kamler M, Jakob H, Lehr HA.

Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H330-5.


Midostaurin upregulates eNOS gene expression and preserves eNOS function in the microcirculation of the mouse.

Li H, Hergert SM, Schäfer SC, Brausch I, Yao Y, Huang Q, Mang C, Lehr HA, Förstermann U.

Nitric Oxide. 2005 Jun;12(4):231-6.


Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer.

Schimanski CC, Schmitz G, Kashyap A, Bosserhoff AK, Bataille F, Schäfer SC, Lehr HA, Berger MR, Galle PR, Strand S, Strand D.

Oncogene. 2005 Apr 28;24(19):3100-9.


Dexamethasone suppresses eNOS and CAT-1 and induces oxidative stress in mouse resistance arterioles.

Schäfer SC, Wallerath T, Closs EI, Schmidt C, Schwarz PM, Förstermann U, Lehr HA.

Am J Physiol Heart Circ Physiol. 2005 Jan;288(1):H436-44. Erratum in: Am J Physiol Heart Circ Physiol. 2005 Dec;289(6):H2752.


Down-regulation of the expression of endothelial NO synthase is likely to contribute to glucocorticoid-mediated hypertension.

Wallerath T, Witte K, Schäfer SC, Schwarz PM, Prellwitz W, Wohlfart P, Kleinert H, Lehr HA, Lemmer B, Förstermann U.

Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13357-62.


Efficacy of desipramine in painful diabetic neuropathy: a placebo-controlled trial.

Max MB, Kishore-Kumar R, Schafer SC, Meister B, Gracely RH, Smoller B, Dubner R.

Pain. 1991 Apr;45(1):3-9; discussion 1-2.


Desipramine relieves postherpetic neuralgia.

Kishore-Kumar R, Max MB, Schafer SC, Gaughan AM, Smoller B, Gracely RH, Dubner R.

Clin Pharmacol Ther. 1990 Mar;47(3):305-12.


Single doses of the serotonin agonists buspirone and m-chlorophenylpiperazine do not relieve neuropathic pain.

Kishore-Kumar R, Schafer SC, Lawlor BA, Murphy DL, Max MB.

Pain. 1989 May;37(2):223-7.


Bradykinin is increased during acute and chronic inflammation: therapeutic implications.

Hargreaves KM, Troullos ES, Dionne RA, Schmidt EA, Schafer SC, Joris JL.

Clin Pharmacol Ther. 1988 Dec;44(6):613-21.


Amitriptyline, but not lorazepam, relieves postherpetic neuralgia.

Max MB, Schafer SC, Culnane M, Smoller B, Dubner R, Gracely RH.

Neurology. 1988 Sep;38(9):1427-32.


Association of pain relief with drug side effects in postherpetic neuralgia: a single-dose study of clonidine, codeine, ibuprofen, and placebo.

Max MB, Schafer SC, Culnane M, Dubner R, Gracely RH.

Clin Pharmacol Ther. 1988 Apr;43(4):363-71.


Amitriptyline relieves diabetic neuropathy pain in patients with normal or depressed mood.

Max MB, Culnane M, Schafer SC, Gracely RH, Walther DJ, Smoller B, Dubner R.

Neurology. 1987 Apr;37(4):589-96.


Alzheimer's disease. Modifying the environment.

Schafer SC.

Geriatr Nurs. 1985 May-Jun;6(3):157-9. No abstract available.


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