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Items: 15


Intratumoral CD8+ T cells with stem cell-like properties: Implications for cancer immunotherapy.

Held W, Siddiqui I, Schaeuble K, Speiser DE.

Sci Transl Med. 2019 Oct 23;11(515). pii: eaay6863. doi: 10.1126/scitranslmed.aay6863. Review.


Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts.

Schaeuble K, Cannelle H, Favre S, Huang HY, Oberle SG, Speiser DE, Zehn D, Luther SA.

PLoS Biol. 2019 Jul 15;17(7):e3000072. doi: 10.1371/journal.pbio.3000072. eCollection 2019 Jul.


Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy.

Siddiqui I, Schaeuble K, Chennupati V, Fuertes Marraco SA, Calderon-Copete S, Pais Ferreira D, Carmona SJ, Scarpellino L, Gfeller D, Pradervand S, Luther SA, Speiser DE, Held W.

Immunity. 2019 Jan 15;50(1):195-211.e10. doi: 10.1016/j.immuni.2018.12.021. Epub 2019 Jan 8.


Lymphatic vessel density is associated with CD8+ T cell infiltration and immunosuppressive factors in human melanoma.

Bordry N, Broggi MAS, de Jonge K, Schaeuble K, Gannon PO, Foukas PG, Danenberg E, Romano E, Baumgaertner P, Fankhauser M, Wald N, Cagnon L, Abed-Maillard S, Maby-El Hajjami H, Murray T, Ioannidou K, Letovanec I, Yan P, Michielin O, Matter M, Swartz MA, Speiser DE.

Oncoimmunology. 2018 May 31;7(8):e1462878. doi: 10.1080/2162402X.2018.1462878. eCollection 2018.


Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis.

Huang HY, Rivas-Caicedo A, Renevey F, Cannelle H, Peranzoni E, Scarpellino L, Hardie DL, Pommier A, Schaeuble K, Favre S, Vogt TK, Arenzana-Seisdedos F, Schneider P, Buckley CD, Donnadieu E, Luther SA.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6826-E6835. doi: 10.1073/pnas.1712628115. Epub 2018 Jul 2.


Perivascular Fibroblasts of the Developing Spleen Act as LTα1β2-Dependent Precursors of Both T and B Zone Organizer Cells.

Schaeuble K, Britschgi MR, Scarpellino L, Favre S, Xu Y, Koroleva E, Lissandrin TKA, Link A, Matloubian M, Ware CF, Nedospasov SA, Tumanov AV, Cyster JG, Luther SA.

Cell Rep. 2017 Nov 28;21(9):2500-2514. doi: 10.1016/j.celrep.2017.10.119.


Essential role of CCL21 in establishment of central self-tolerance in T cells.

Kozai M, Kubo Y, Katakai T, Kondo H, Kiyonari H, Schaeuble K, Luther SA, Ishimaru N, Ohigashi I, Takahama Y.

J Exp Med. 2017 Jul 3;214(7):1925-1935. doi: 10.1084/jem.20161864. Epub 2017 Jun 13.


Inflammation-Induced CCR7 Oligomers Form Scaffolds to Integrate Distinct Signaling Pathways for Efficient Cell Migration.

Hauser MA, Schaeuble K, Kindinger I, Impellizzieri D, Krueger WA, Hauck CR, Boyman O, Legler DF.

Immunity. 2016 Jan 19;44(1):59-72. doi: 10.1016/j.immuni.2015.12.010.


Ubiquitylation of the chemokine receptor CCR7 enables efficient receptor recycling and cell migration.

Schaeuble K, Hauser MA, Rippl AV, Bruderer R, Otero C, Groettrup M, Legler DF.

J Cell Sci. 2012 Oct 1;125(Pt 19):4463-74. doi: 10.1242/jcs.097519. Epub 2012 Jul 13.


Cross-talk between TCR and CCR7 signaling sets a temporal threshold for enhanced T lymphocyte migration.

Schaeuble K, Hauser MA, Singer E, Groettrup M, Legler DF.

J Immunol. 2011 Dec 1;187(11):5645-52. doi: 10.4049/jimmunol.1101850. Epub 2011 Oct 31.


Adolescents' preferences for primary care provider interactions.

Schaeuble K, Haglund K, Vukovich M.

J Spec Pediatr Nurs. 2010 Jul;15(3):202-10. doi: 10.1111/j.1744-6155.2010.00232.x.


Distinct motifs in the chemokine receptor CCR7 regulate signal transduction, receptor trafficking and chemotaxis.

Otero C, Eisele PS, Schaeuble K, Groettrup M, Legler DF.

J Cell Sci. 2008 Aug 15;121(Pt 16):2759-67. doi: 10.1242/jcs.029074. Epub 2008 Jul 29.


Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence.

Passos JF, Saretzki G, Ahmed S, Nelson G, Richter T, Peters H, Wappler I, Birket MJ, Harold G, Schaeuble K, Birch-Machin MA, Kirkwood TB, von Zglinicki T.

PLoS Biol. 2007 May;5(5):e110.


Commuting (to) suicide: an update on nucleocytoplasmic transport in apoptosis.

Grote P, Schaeuble K, Ferrando-May E.

Arch Biochem Biophys. 2007 Jun 15;462(2):156-61. Epub 2007 Mar 8. Review.


Role of reduced lipoic acid in the redox regulation of mitochondrial aldehyde dehydrogenase (ALDH-2) activity. Implications for mitochondrial oxidative stress and nitrate tolerance.

Wenzel P, Hink U, Oelze M, Schuppan S, Schaeuble K, Schildknecht S, Ho KK, Weiner H, Bachschmid M, Münzel T, Daiber A.

J Biol Chem. 2007 Jan 5;282(1):792-9. Epub 2006 Nov 13.

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