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Items: 22

1.

Metabolic profiles show specific mitochondrial toxicities in vitro in myotube cells.

Xu Q, Vu H, Liu L, Wang TC, Schaefer WH.

J Biomol NMR. 2011 Apr;49(3-4):207-19. doi: 10.1007/s10858-011-9482-8. Epub 2011 Feb 26.

PMID:
21359514
2.

Metabolomics in pharmaceutical research and development: metabolites, mechanisms and pathways.

Xu EY, Schaefer WH, Xu Q.

Curr Opin Drug Discov Devel. 2009 Jan;12(1):40-52. Review.

PMID:
19152212
3.

Reaction of primary and secondary amines to form carbamic acid glucuronides.

Schaefer WH.

Curr Drug Metab. 2006 Dec;7(8):873-81. Review.

PMID:
17168688
4.
5.

Statins induce apoptosis in rat and human myotube cultures by inhibiting protein geranylgeranylation but not ubiquinone.

Johnson TE, Zhang X, Bleicher KB, Dysart G, Loughlin AF, Schaefer WH, Umbenhauer DR.

Toxicol Appl Pharmacol. 2004 Nov 1;200(3):237-50.

PMID:
15504460
6.

Evaluation of ubiquinone concentration and mitochondrial function relative to cerivastatin-induced skeletal myopathy in rats.

Schaefer WH, Lawrence JW, Loughlin AF, Stoffregen DA, Mixson LA, Dean DC, Raab CE, Yu NX, Lankas GR, Frederick CB.

Toxicol Appl Pharmacol. 2004 Jan 1;194(1):10-23.

PMID:
14728975
7.

High-performance liquid-chromatographic determination of warfarin enantiomers in plasma with automated on-line sample enrichment.

Boppana VK, Schaefer WH, Cyronak MJ.

J Biochem Biophys Methods. 2002 Dec 31;54(1-3):315-26.

PMID:
12543507
8.
9.

Metabolism of carvedilol in dogs, rats, and mice.

Schaefer WH, Politowski J, Hwang B, Dixon F Jr, Goalwin A, Gutzait L, Anderson K, DeBrosse C, Bean M, Rhodes GR.

Drug Metab Dispos. 1998 Oct;26(10):958-69.

PMID:
9763400
10.

Application of liquid chromatography-mass spectrometry(n) analyses to the characterization of novel glyburide metabolites formed in vitro.

Tiller PR, Land AP, Jardine I, Murphy DM, Sozio R, Ayrton A, Schaefer WH.

J Chromatogr A. 1998 Jan 23;794(1-2):15-25.

PMID:
9491553
12.

Renal catabolism of recombinant human soluble CD4 after intravenous administration to male Sprague-Dawley rats.

Hepburn TW, Davis CB, Urbanski JJ, Smith BR, Schaefer WH, Carbonaro MA, Bugelski PJ.

Drug Metab Dispos. 1995 Oct;23(10):1044-50.

PMID:
8654191
13.

A liquid chromatographic assay for the stereospecific quantitative analysis of halofantrine in human plasma.

Brocks DR, Dennis MJ, Schaefer WH.

J Pharm Biomed Anal. 1995 Jun;13(7):911-8.

PMID:
8562616
14.

Isolation and identification of singlet oxygen oxidation products of beta-carotene.

Stratton SP, Schaefer WH, Liebler DC.

Chem Res Toxicol. 1993 Jul-Aug;6(4):542-7.

PMID:
8374054
15.

Formation of mitochondrial phospholipid adducts by nephrotoxic cysteine conjugate metabolites.

Hayden PJ, Welsh CJ, Yang Y, Schaefer WH, Ward AJ, Stevens JL.

Chem Res Toxicol. 1992 Mar-Apr;5(2):232-7.

PMID:
1643252
16.

Formation of a carbamoyl glucuronide conjugate of carvedilol in vitro using dog and rat liver microsomes.

Schaefer WH.

Drug Metab Dispos. 1992 Jan-Feb;20(1):130-3. No abstract available.

PMID:
1346989
18.

Reaction of the model thiol 2-mercaptoethanol and glutathione with methylvinylmaleimide, a Michael acceptor with extended conjugation.

Schaefer WH, Harris TM, Guengerich FP.

Arch Biochem Biophys. 1987 Aug 15;257(1):186-93.

PMID:
3631963
19.

A mutant Paramecium with a defective calcium-dependent potassium conductance has an altered calmodulin: a nonlethal selective alteration in calmodulin regulation.

Schaefer WH, Hinrichsen RD, Burgess-Cassler A, Kung C, Blair IA, Watterson DM.

Proc Natl Acad Sci U S A. 1987 Jun;84(11):3931-5.

20.

Amino acid sequence of a novel calmodulin from Paramecium tetraurelia that contains dimethyllysine in the first domain.

Schaefer WH, Lukas TJ, Blair IA, Schultz JE, Watterson DM.

J Biol Chem. 1987 Jan 25;262(3):1025-9.

21.

Characterization of the enzymatic and nonenzymatic peroxidative degradation of iron porphyrins and cytochrome P-450 heme.

Schaefer WH, Harris TM, Guengerich FP.

Biochemistry. 1985 Jun 18;24(13):3254-63.

PMID:
3927975
22.

[ON THE CLINICAL ASPECTS OF GENERALIZED BOECK'S SARCOIDOSIS WITH INTRACEREBRAL FOCI].

DEGKWITZ R, SCHAEFER WH.

Nervenarzt. 1965 Feb;36:70-2. German. No abstract available.

PMID:
14266010

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