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Effects of weight change on apolipoprotein B-containing emerging atherosclerotic cardiovascular disease (ASCVD) risk factors.

Dansinger ML, Williams PT, Superko HR, Schaefer EJ.

Lipids Health Dis. 2019 Jul 17;18(1):154. doi: 10.1186/s12944-019-1094-4.


Direct Versus Calculated LDL Cholesterol and C-Reactive Protein in Cardiovascular Disease Risk Assessment in the Framingham Offspring Study.

Ikezaki H, Fisher VA, Lim E, Ai M, Liu CT, Adrienne Cupples L, Nakajima K, Asztalos BF, Furusyo N, Schaefer EJ.

Clin Chem. 2019 Sep;65(9):1102-1114. doi: 10.1373/clinchem.2019.304600. Epub 2019 Jun 25.


First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography-Urgent need for harmonisation of analytical methods.

Lütjohann D, Björkhem I, Friedrichs S, Kerksiek A, Lövgren-Sandblom A, Geilenkeuser WJ, Ahrends R, Andrade I, Ansorena D, Astiasarán I, Baila-Rueda L, Barriuso B, Becker S, Bretillon L, Browne RW, Caccia C, Ceglarek U, Cenarro A, Crick PJ, Fauler G, Garcia-Llatas G, Gray R, Griffiths WJ, Gylling H, Harding S, Helmschrodt C, Iuliano L, Janssen HG, Jones P, Kaipiainen L, Kannenberg F, Lagarda MJ, Leoni V, Lottenberg AM, MacKay DS, Matysik S, McDonald J, Menendez-Carreño M, Myrie SB, Sutti Nunes V, Ostlund RE, Polisecki E, Ramos F, Rideout TC, Schaefer EJ, Schmitz G, Wang Y, Zerbinati C, Diczfalusy U, Schött HF.

J Steroid Biochem Mol Biol. 2019 Jun;190:115-125. doi: 10.1016/j.jsbmb.2019.03.025. Epub 2019 Mar 30.


The importance of cholesterol follow-up testing under current statin treatment guidelines.

Dansinger ML, Williams PT, Superko HR, Schaefer EJ.

Prev Med. 2019 Apr;121:150-157. doi: 10.1016/j.ypmed.2019.02.003. Epub 2019 Feb 8.


Lipoprotein Subfractions and Glucose Homeostasis in Prediabetes and Diabetes in Taiwan.

Hsu H, Hsu P, Cheng MH, Ito Y, Kanda E, Schaefer EJ, Ai M.

J Atheroscler Thromb. 2019 Feb 7. doi: 10.5551/jat.48330. [Epub ahead of print]


The biochemical and genetic diagnosis of lipid disorders.

Schaefer EJ, Geller AS, Endress G.

Curr Opin Lipidol. 2019 Apr;30(2):56-62. doi: 10.1097/MOL.0000000000000590.


Effects of weight change on HDL-cholesterol and its subfractions in over 28,000 men and women.

Dansinger M, Williams PT, Superko HR, Asztalos BF, Schaefer EJ.

J Clin Lipidol. 2019 Mar - Apr;13(2):308-316. doi: 10.1016/j.jacl.2018.12.001. Epub 2018 Dec 18.


Extreme hypertriglyceridemia: Genetic diversity, pancreatitis, pregnancy, and prevalence.

Chyzhyk V, Kozmic S, Brown AS, Hudgins LC, Starc TJ, Davila AD, Blevins TC, Diffenderfer MR, He L, Geller AS, Rush C, Hegele RA, Schaefer EJ.

J Clin Lipidol. 2019 Jan - Feb;13(1):89-99. doi: 10.1016/j.jacl.2018.09.007. Epub 2018 Sep 18.


Genetic and secondary causes of severe HDL deficiency and cardiovascular disease.

Geller AS, Polisecki EY, Diffenderfer MR, Asztalos BF, Karathanasis SK, Hegele RA, Schaefer EJ.

J Lipid Res. 2018 Dec;59(12):2421-2435. doi: 10.1194/jlr.M088203. Epub 2018 Oct 17.


Unusual genetic variants associated with hypercholesterolemia in Argentina.

Corral P, Geller AS, Polisecki EY, Lopez GI, Bañares VG, Cacciagiu L, Berg G, Hegele RA, Schaefer EJ, Schreier LE.

Atherosclerosis. 2018 Oct;277:256-261. doi: 10.1016/j.atherosclerosis.2018.06.009.


Significance of Clonal Mutations in Bone Marrow Failure and Inherited Myelodysplastic Syndrome/Acute Myeloid Leukemia Predisposition Syndromes.

Schaefer EJ, Lindsley RC.

Hematol Oncol Clin North Am. 2018 Aug;32(4):643-655. doi: 10.1016/j.hoc.2018.03.005. Epub 2018 May 1. Review.


Diagnosis, treatment, and clinical outcomes in 43 cases with cerebrotendinous xanthomatosis.

Duell PB, Salen G, Eichler FS, DeBarber AE, Connor SL, Casaday L, Jayadev S, Kisanuki Y, Lekprasert P, Malloy MJ, Ramdhani RA, Ziajka PE, Quinn JF, Su KG, Geller AS, Diffenderfer MR, Schaefer EJ.

J Clin Lipidol. 2018 Sep - Oct;12(5):1169-1178. doi: 10.1016/j.jacl.2018.06.008. Epub 2018 Jun 22.


High-Density Lipoprotein Particles, Cell-Cholesterol Efflux, and Coronary Heart Disease Risk.

Asztalos BF, Horvath KV, Schaefer EJ.

Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):2007-2015. doi: 10.1161/ATVBAHA.118.311117.


Differential Effects of Estrogen and Progestin on Apolipoprotein B100 and B48 Kinetics in Postmenopausal Women.

Lamon-Fava S, Diffenderfer MR, Barrett PHR, Wan WY, Postfai B, Nartsupha C, Dolnikowski GG, Schaefer EJ.

Lipids. 2018 Feb;53(2):167-175. doi: 10.1002/lipd.12011. Epub 2018 Mar 14.


HDL Particle Measurement: Comparison of 5 Methods.

Matera R, Horvath KV, Nair H, Schaefer EJ, Asztalos BF.

Clin Chem. 2018 Mar;64(3):492-500. doi: 10.1373/clinchem.2017.277632. Epub 2017 Dec 4.


The association between hypercholesterolemia and sitosterolemia, and report of a sitosterolemia kindred.

Brinton EA, Hopkins PN, Hegele RA, Geller AS, Polisecki EY, Diffenderfer MR, Schaefer EJ.

J Clin Lipidol. 2018 Jan - Feb;12(1):152-161. doi: 10.1016/j.jacl.2017.10.013. Epub 2017 Oct 27.


Higher dietary cholesterol and ω-3 fatty acid intakes are associated with a lower success rate of Helicobacter pylori eradication therapy in Japan.

Ikezaki H, Furusyo N, Jacques PF, Shimizu M, Murata M, Schaefer EJ, Urita Y, Hayashi J.

Am J Clin Nutr. 2017 Aug;106(2):581-588. doi: 10.3945/ajcn.116.144873. Epub 2017 Jun 28.


Cardiovascular disease prevalence and insulin resistance in the Kyushu-Okinawa Population Study and the Framingham Offspring Study.

Ikezaki H, Ai M, Schaefer EJ, Otokozawa S, Asztalos BF, Nakajima K, Zhou Y, Liu CT, Jacques PF, Cupples LA, Furusyo N.

J Clin Lipidol. 2017 Mar - Apr;11(2):348-356. doi: 10.1016/j.jacl.2017.01.014. Epub 2017 Feb 3.


Influence of HDL particles on cell-cholesterol efflux under various pathological conditions.

Asztalos BF, Horvath KV, Mehan M, Yokota Y, Schaefer EJ.

J Lipid Res. 2017 Jun;58(6):1238-1246. doi: 10.1194/jlr.M075648. Epub 2017 Apr 18.


Metabolism and proteomics of large and small dense LDL in combined hyperlipidemia: effects of rosuvastatin.

Thongtang N, Diffenderfer MR, Ooi EMM, Barrett PHR, Turner SM, Le NA, Brown WV, Schaefer EJ.

J Lipid Res. 2017 Jul;58(7):1315-1324. doi: 10.1194/jlr.M073882. Epub 2017 Apr 9.


Salsalate improves glycaemia in overweight persons with diabetes risk factors of stable statin-treated cardiovascular disease: A 30-month randomized placebo-controlled trial.

Salastekar N, Desai T, Hauser T, Schaefer EJ, Fowler K, Joseph S, Shoelson SE, Goldfine AB; TINSAL-CVD study team.

Diabetes Obes Metab. 2017 Oct;19(10):1458-1462. doi: 10.1111/dom.12940. Epub 2017 Jul 6.


Ethnic Differences in Glucose Homeostasis Markers between the Kyushu-Okinawa Population Study and the Framingham Offspring Study.

Ikezaki H, Ai M, Schaefer EJ, Otokozawa S, Asztalos BF, Nakajima K, Zhou Y, Liu CT, Jacques PF, Cupples LA, Furusyo N.

Sci Rep. 2016 Nov 10;6:36725. doi: 10.1038/srep36725.


Effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular disease risk factors: a randomized clinical trial.

Asztalos IB, Gleason JA, Sever S, Gedik R, Asztalos BF, Horvath KV, Dansinger ML, Lamon-Fava S, Schaefer EJ.

Metabolism. 2016 Nov;65(11):1636-1645. doi: 10.1016/j.metabol.2016.07.010. Epub 2016 Aug 26.


Comparing fluorescence-based cell-free assays for the assessment of antioxidative capacity of high-density lipoproteins.

Tsunoda F, Lamon-Fava S, Horvath KV, Schaefer EJ, Asztalos BF.

Lipids Health Dis. 2016 Sep 22;15(1):163.


High-density lipoprotein subpopulation profiles in lipoprotein lipase and hepatic lipase deficiency.

Tani M, Horvath KV, Lamarche B, Couture P, Burnett JR, Schaefer EJ, Asztalos BF.

Atherosclerosis. 2016 Oct;253:7-14. doi: 10.1016/j.atherosclerosis.2016.08.014. Epub 2016 Aug 20.


Diagnosis and treatment of high density lipoprotein deficiency.

Schaefer EJ, Anthanont P, Diffenderfer MR, Polisecki E, Asztalos BF.

Prog Cardiovasc Dis. 2016 Sep - Oct;59(2):97-106. doi: 10.1016/j.pcad.2016.08.006. Epub 2016 Aug 24. Review.


Effect of Targeting Inflammation With Salsalate: The TINSAL-CVD Randomized Clinical Trial on Progression of Coronary Plaque in Overweight and Obese Patients Using Statins.

Hauser TH, Salastekar N, Schaefer EJ, Desai T, Goldfine HL, Fowler KM, Weber GM, Welty F, Clouse M, Shoelson SE, Goldfine AB; Targeting Inflammation Using Salsalate in Cardiovascular Disease (TINSAL-CVD) Study Team.

JAMA Cardiol. 2016 Jul 1;1(4):413-23. doi: 10.1001/jamacardio.2016.0605.


The Measurement of Lipids, Lipoproteins, Apolipoproteins, Fatty Acids, and Sterols, and Next Generation Sequencing for the Diagnosis and Treatment of Lipid Disorders.

Schaefer EJ, Tsunoda F, Diffenderfer M, Polisecki E, Thai N, Asztalos B.

In: Feingold KR, Anawalt B, Boyce A, Chrousos G, Dungan K, Grossman A, Hershman JM, Kaltsas G, Koch C, Kopp P, Korbonits M, McLachlan R, Morley JE, New M, Perreault L, Purnell J, Rebar R, Singer F, Trence DL, Vinik A, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA):, Inc.; 2000-.
2016 Mar 29.


Distinct metabolism of apolipoproteins (a) and B-100 within plasma lipoprotein(a).

Diffenderfer MR, Lamon-Fava S, Marcovina SM, Barrett PH, Lel J, Dolnikowski GG, Berglund L, Schaefer EJ.

Metabolism. 2016 Apr;65(4):381-90. doi: 10.1016/j.metabol.2015.10.031. Epub 2015 Nov 6.


Fenofibrate, HDL, and cardiovascular disease in Type-2 diabetes: The DAIS trial.

Tsunoda F, Asztalos IB, Horvath KV, Steiner G, Schaefer EJ, Asztalos BF.

Atherosclerosis. 2016 Apr;247:35-39. doi: 10.1016/j.atherosclerosis.2016.01.028. Epub 2016 Jan 22.


Effects of carbohydrate quantity and glycemic index on resting metabolic rate and body composition during weight loss.

Karl JP, Roberts SB, Schaefer EJ, Gleason JA, Fuss P, Rasmussen H, Saltzman E, Das SK.

Obesity (Silver Spring). 2015 Nov;23(11):2190-8. doi: 10.1002/oby.21268.


Identification and metabolic profiling of patients with lysosomal acid lipase deficiency.

Pullinger CR, Stock EO, Movsesyan I, Malloy MJ, Frost PH, Tripuraneni R, Quinn AG, Ishida BY, Schaefer EJ, Asztalos BF, Kane JP.

J Clin Lipidol. 2015 Sep-Oct;9(5):716-26.e1. doi: 10.1016/j.jacl.2015.07.008. Epub 2015 Jul 26.


A comparison of glycated albumin and glycosylated hemoglobin for the screening of diabetes mellitus in Taiwan.

Hsu P, Ai M, Kanda E, Yu NC, Chen HL, Chen HW, Cheng MH, Kohzuma T, Schaefer EJ, Yoshida M.

Atherosclerosis. 2015 Sep;242(1):327-33. doi: 10.1016/j.atherosclerosis.2015.07.037. Epub 2015 Jul 26.


Effects of oral eicosapentaenoic acid versus docosahexaenoic acid on human peripheral blood mononuclear cell gene expression.

Tsunoda F, Lamon-Fava S, Asztalos BF, Iyer LK, Richardson K, Schaefer EJ.

Atherosclerosis. 2015 Aug;241(2):400-8. doi: 10.1016/j.atherosclerosis.2015.05.015. Epub 2015 May 19.


Case report: A novel apolipoprotein A-I missense mutation apoA-I (Arg149Ser)Boston associated with decreased lecithin-cholesterol acyltransferase activation and cellular cholesterol efflux.

Anthanont P, Asztalos BF, Polisecki E, Zachariah B, Schaefer EJ.

J Clin Lipidol. 2015 May-Jun;9(3):390-5. doi: 10.1016/j.jacl.2015.02.005. Epub 2015 Mar 5.


Cardiovascular disease protection in long-duration type 1 diabetes and sex differences.

He ZH, D'Eon SA, Tinsley LJ, Fitzgerald S, Hastings SM, Khamaisi M, Sun JK, Turek SJ, Schaefer EJ, King GL, Keenan HA.

Diabetes Care. 2015 May;38(5):e73-4. doi: 10.2337/dc15-0017. No abstract available.


Glycated albumin as a diagnostic tool for diabetes in a general Japanese population.

Ikezaki H, Furusyo N, Ihara T, Hayashi T, Ura K, Hiramine S, Mitsumoto F, Takayama K, Murata M, Kohzuma T, Ai M, Schaefer EJ, Hayashi J.

Metabolism. 2015 Jun;64(6):698-705. doi: 10.1016/j.metabol.2015.03.003. Epub 2015 Mar 14.


Rosuvastatin Enhances the Catabolism of LDL apoB-100 in Subjects with Combined Hyperlipidemia in a Dose Dependent Manner.

Le NA, Diffenderfer MR, Thongtang N, Ooi EM, Barrett PH, Horvath KV, Dolnikowski GG, Asztalos BF, Schaefer EJ, Brown WV.

Lipids. 2015 May;50(5):447-58. doi: 10.1007/s11745-015-4005-0. Epub 2015 Mar 26.


Effects of the anti-inflammatory drug salsalate on bone turnover in type 2 diabetes mellitus.

Rubin MR, Goldfine AB, McMahon DJ, Donovan DS, Cremers S, Dworakowski E, Schaefer EJ, Shoelson SE, Silverberg SJ.

Endocrine. 2015 Nov;50(2):504-7. doi: 10.1007/s12020-015-0535-8. Epub 2015 Feb 1. No abstract available.


Obesity associated molecular forms of C-reactive protein in human.

Asztalos BF, Horan MS, Horvath KV, McDermott AY, Chalasani NP, Schaefer EJ.

PLoS One. 2014 Oct 9;9(10):e109238. doi: 10.1371/journal.pone.0109238. eCollection 2014.


Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function.

Mak AC, Pullinger CR, Tang LF, Wong JS, Deo RC, Schwarz JM, Gugliucci A, Movsesyan I, Ishida BY, Chu C, Poon A, Kim P, Stock EO, Schaefer EJ, Asztalos BF, Castellano JM, Wyss-Coray T, Duncan JL, Miller BL, Kane JP, Kwok PY, Malloy MJ.

JAMA Neurol. 2014 Oct;71(10):1228-36. doi: 10.1001/jamaneurol.2014.2011.


A novel ApoA-I truncation (ApoA-IMytilene) associated with decreased ApoA-I production.

Anthanont P, Polisecki E, Asztalos BF, Diffenderfer MR, Barrett PH, Millar JS, Billheimer J, Cuchel M, Rader DJ, Schaefer EJ.

Atherosclerosis. 2014 Aug;235(2):470-6. doi: 10.1016/j.atherosclerosis.2014.05.935. Epub 2014 Jun 2.


ABCA1 gene variation and heart disease risk reduction in the elderly during pravastatin treatment.

Akao H, Polisecki E, Schaefer EJ, Trompet S, Robertson M, Ford I, Jukema JW, de Craen AJ, Packard C, Buckley BM, Kajinami K; PROspective Study of Pravastatin in the Elderly at Risk Investigator.

Atherosclerosis. 2014 Jul;235(1):176-81. doi: 10.1016/j.atherosclerosis.2014.04.030. Epub 2014 May 8.


The composition and metabolism of large and small LDL.

Diffenderfer MR, Schaefer EJ.

Curr Opin Lipidol. 2014 Jun;25(3):221-6. doi: 10.1097/MOL.0000000000000067. Review.


Editorial introduction.

Schaefer EJ.

Curr Opin Lipidol. 2014 Jun;25(3):159-60. doi: 10.1097/MOL.0000000000000082. No abstract available.


High-density lipoprotein metabolism, composition, function, and deficiency.

Schaefer EJ, Anthanont P, Asztalos BF.

Curr Opin Lipidol. 2014 Jun;25(3):194-9. doi: 10.1097/MOL.0000000000000074. Review.


A kindred with fish eye disease, corneal opacities, marked high-density lipoprotein deficiency, and statin therapy.

Dimick SM, Sallee B, Asztalos BF, Pritchard PH, Frohlich J, Schaefer EJ.

J Clin Lipidol. 2014 Mar-Apr;8(2):223-30. doi: 10.1016/j.jacl.2013.11.005. Epub 2013 Dec 11.


The influence of apoE-deficiency and LDL-receptor-deficiency on the HDL subpopulation profile in mice and in humans.

Tani M, Matera R, Horvath KV, Hasan TS, Schaefer EJ, Asztalos BF.

Atherosclerosis. 2014 Mar;233(1):39-44. doi: 10.1016/j.atherosclerosis.2013.11.080. Epub 2013 Dec 31.


Favorable effects of ezetimibe alone or in association with simvastatin on the removal from plasma of chylomicrons in coronary heart disease subjects.

Mangili OC, Moron Gagliardi AC, Mangili LC, Mesquita CH, Machado Cesar LA, Tanaka A, Schaefer EJ, Maranhão RC, Santos RD.

Atherosclerosis. 2014 Mar;233(1):319-25. doi: 10.1016/j.atherosclerosis.2013.12.008. Epub 2014 Jan 17.


Serum cholesterol and triglyceride reference ranges of twenty lipoprotein subclasses for healthy Japanese men and women.

Furusyo N, Ai M, Okazaki M, Ikezaki H, Ihara T, Hayashi T, Hiramine S, Ura K, Kohzuma T, Schaefer EJ, Hayashi J.

Atherosclerosis. 2013 Dec;231(2):238-45. doi: 10.1016/j.atherosclerosis.2013.09.008. Epub 2013 Oct 1.


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