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Items: 33


Ligand Identity-Induced Generation of Enhanced Oxidative Hydrogen Atom Transfer Reactivity for a CuII2(O2•-) Complex Driven by Formation of a CuII2(-OOH) Compound with a Strong O-H Bond.

Quist DA, Ehudin MA, Schaefer AW, Schneider GL, Solomon EI, Karlin KD.

J Am Chem Soc. 2019 Aug 14;141(32):12682-12696. doi: 10.1021/jacs.9b05277. Epub 2019 Jul 30.


Geometric and Electronic Structure Contributions to O-O Cleavage and the Resultant Intermediate Generated in Heme-Copper Oxidases.

Schaefer AW, Roveda AC Jr, Jose A, Solomon EI.

J Am Chem Soc. 2019 Jun 26;141(25):10068-10081. doi: 10.1021/jacs.9b04271. Epub 2019 Jun 17.


Influence of intramolecular secondary sphere hydrogen-bonding interactions on cytochrome c oxidase inspired low-spin heme-peroxo-copper complexes.

Ehudin MA, Schaefer AW, Adam SM, Quist DA, Diaz DE, Tang JA, Solomon EI, Karlin KD.

Chem Sci. 2019 Jan 4;10(10):2893-2905. doi: 10.1039/c8sc05165h. eCollection 2019 Mar 14.


Spin Interconversion of Heme-Peroxo-Copper Complexes Facilitated by Intramolecular Hydrogen-Bonding Interactions.

Schaefer AW, Ehudin MA, Quist DA, Tang JA, Karlin KD, Solomon EI.

J Am Chem Soc. 2019 Mar 27;141(12):4936-4951. doi: 10.1021/jacs.9b00118. Epub 2019 Mar 14.


A Six-Coordinate Peroxynitrite Low-Spin Iron(III) Porphyrinate Complex-The Product of the Reaction of Nitrogen Monoxide (·NO(g)) with a Ferric-Superoxide Species.

Sharma SK, Schaefer AW, Lim H, Matsumura H, Moënne-Loccoz P, Hedman B, Hodgson KO, Solomon EI, Karlin KD.

J Am Chem Soc. 2017 Dec 6;139(48):17421-17430. doi: 10.1021/jacs.7b08468. Epub 2017 Nov 21.


Phenol-Induced O-O Bond Cleavage in a Low-Spin Heme-Peroxo-Copper Complex: Implications for O2 Reduction in Heme-Copper Oxidases.

Schaefer AW, Kieber-Emmons MT, Adam SM, Karlin KD, Solomon EI.

J Am Chem Soc. 2017 Jun 14;139(23):7958-7973. doi: 10.1021/jacs.7b03292. Epub 2017 Jun 6.


Critical Aspects of Heme-Peroxo-Cu Complex Structure and Nature of Proton Source Dictate Metal-O(peroxo) Breakage versus Reductive O-O Cleavage Chemistry.

Adam SM, Garcia-Bosch I, Schaefer AW, Sharma SK, Siegler MA, Solomon EI, Karlin KD.

J Am Chem Soc. 2017 Jan 11;139(1):472-481. doi: 10.1021/jacs.6b11322. Epub 2016 Dec 28.


Local Arp2/3-dependent actin assembly modulates applied traction force during apCAM adhesion site maturation.

Buck KB, Schaefer AW, Schoonderwoert VT, Creamer MS, Dufresne ER, Forscher P.

Mol Biol Cell. 2017 Jan 1;28(1):98-110. doi: 10.1091/mbc.E16-04-0228. Epub 2016 Nov 16.


A "naked" Fe(III)-(O₂²⁻)-Cu(II) species allows for structural and spectroscopic tuning of low-spin heme-peroxo-Cu complexes.

Garcia-Bosch I, Adam SM, Schaefer AW, Sharma SK, Peterson RL, Solomon EI, Karlin KD.

J Am Chem Soc. 2015 Jan 28;137(3):1032-5. doi: 10.1021/ja5115198. Epub 2015 Jan 16.


Elastic coupling of nascent apCAM adhesions to flowing actin networks.

Mejean CO, Schaefer AW, Buck KB, Kress H, Shundrovsky A, Merrill JW, Dufresne ER, Forscher P.

PLoS One. 2013 Sep 6;8(9):e73389. doi: 10.1371/journal.pone.0073389. eCollection 2013.


The role of actin turnover in retrograde actin network flow in neuronal growth cones.

Van Goor D, Hyland C, Schaefer AW, Forscher P.

PLoS One. 2012;7(2):e30959. doi: 10.1371/journal.pone.0030959. Epub 2012 Feb 16.


Enhanced mobility-lifetime products in PbS colloidal quantum dot photovoltaics.

Jeong KS, Tang J, Liu H, Kim J, Schaefer AW, Kemp K, Levina L, Wang X, Hoogland S, Debnath R, Brzozowski L, Sargent EH, Asbury JB.

ACS Nano. 2012 Jan 24;6(1):89-99. doi: 10.1021/nn2039164. Epub 2011 Dec 22.


Multiplexed force measurements on live cells with holographic optical tweezers.

Mejean CO, Schaefer AW, Millman EA, Forscher P, Dufresne ER.

Opt Express. 2009 Apr 13;17(8):6209-17.


Myosin II activity facilitates microtubule bundling in the neuronal growth cone neck.

Burnette DT, Ji L, Schaefer AW, Medeiros NA, Danuser G, Forscher P.

Dev Cell. 2008 Jul;15(1):163-9. doi: 10.1016/j.devcel.2008.05.016.


Coordination of actin filament and microtubule dynamics during neurite outgrowth.

Schaefer AW, Schoonderwoert VT, Ji L, Mederios N, Danuser G, Forscher P.

Dev Cell. 2008 Jul;15(1):146-62. doi: 10.1016/j.devcel.2008.05.003.


Migration of transplanted neural progenitor cells in a ferret model of cortical dysplasia.

Schaefer AW, Juliano SL.

Exp Neurol. 2008 Mar;210(1):67-82. Epub 2007 Oct 23.


Filopodial actin bundles are not necessary for microtubule advance into the peripheral domain of Aplysia neuronal growth cones.

Burnette DT, Schaefer AW, Ji L, Danuser G, Forscher P.

Nat Cell Biol. 2007 Dec;9(12):1360-9. Epub 2007 Nov 18.


Microtubule dynamics are necessary for SRC family kinase-dependent growth cone steering.

Suter DM, Schaefer AW, Forscher P.

Curr Biol. 2004 Jul 13;14(13):1194-9.


Real-time digital signal processing-based optical coherence tomography and Doppler optical coherence tomography.

Schaefer AW, Reynolds JJ, Marks DL, Boppart SA.

IEEE Trans Biomed Eng. 2004 Jan;51(1):186-90.


Rho-dependent contractile responses in the neuronal growth cone are independent of classical peripheral retrograde actin flow.

Zhang XF, Schaefer AW, Burnette DT, Schoonderwoert VT, Forscher P.

Neuron. 2003 Dec 4;40(5):931-44.


Conserved microtubule-actin interactions in cell movement and morphogenesis.

Rodriguez OC, Schaefer AW, Mandato CA, Forscher P, Bement WM, Waterman-Storer CM.

Nat Cell Biol. 2003 Jul;5(7):599-609. Review.


L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1.

Schaefer AW, Kamei Y, Kamiguchi H, Wong EV, Rapoport I, Kirchhausen T, Beach CM, Landreth G, Lemmon SK, Lemmon V.

J Cell Biol. 2002 Jun 24;157(7):1223-32. Epub 2002 Jun 24.


The status of Linshcosteus in the Triatominae (Hemiptera: Reduviidae).

Schaefer AW, Coscarón MC.

J Med Entomol. 2001 Nov;38(6):862-7.


Protein kinase C activation promotes microtubule advance in neuronal growth cones by increasing average microtubule growth lifetimes.

Kabir N, Schaefer AW, Nakhost A, Sossin WS, Forscher P.

J Cell Biol. 2001 Mar 5;152(5):1033-44.


Activation of the MAPK signal cascade by the neural cell adhesion molecule L1 requires L1 internalization.

Schaefer AW, Kamiguchi H, Wong EV, Beach CM, Landreth G, Lemmon V.

J Biol Chem. 1999 Dec 31;274(53):37965-73.


The neural cell adhesion molecule L1 interacts with the AP-2 adaptor and is endocytosed via the clathrin-mediated pathway.

Kamiguchi H, Long KE, Pendergast M, Schaefer AW, Rapoport I, Kirchhausen T, Lemmon V.

J Neurosci. 1998 Jul 15;18(14):5311-21.


Involvement of p90rsk in neurite outgrowth mediated by the cell adhesion molecule L1.

Wong EV, Schaefer AW, Landreth G, Lemmon V.

J Biol Chem. 1996 Jul 26;271(30):18217-23.


Casein kinase II phosphorylates the neural cell adhesion molecule L1.

Wong EV, Schaefer AW, Landreth G, Lemmon V.

J Neurochem. 1996 Feb;66(2):779-86.


Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1.

Zhang W, Wagner BJ, Ehrenman K, Schaefer AW, DeMaria CT, Crater D, DeHaven K, Long L, Brewer G.

Mol Cell Biol. 1993 Dec;13(12):7652-65.


Galactosyl transferase-dependence of neurite outgrowth on substratum-bound laminin.

Thomas WA, Schaefer AW, Treadway RM Jr.

Development. 1990 Dec;110(4):1101-14.


Variation in the rate of DNA chain growth through the S phase in HeLa cells.

Painter RB, Schaefer AW.

J Mol Biol. 1971 May 28;58(1):289-95. No abstract available.


Rate of synthesis along replicons of different kinds of mammalian cells.

Painter RB, Schaefer AW.

J Mol Biol. 1969 Nov 14;45(3):467-79. No abstract available.


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