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Items: 1 to 50 of 68

1.

Effects of glycine, pyruvate, resveratrol, and nitrite on tissue injury and cytokine response in endotoxemic rats.

Hamburger T, Broecker-Preuss M, Hartmann M, Schade FU, de Groot H, Petrat F.

J Surg Res. 2013 Jul;183(1):e7-e21. doi: 10.1016/j.jss.2013.01.024. Epub 2013 Feb 8.

PMID:
23434211
2.

Modulation of dendritic cell differentiation in the bone marrow mediates sustained immunosuppression after polymicrobial sepsis.

Pastille E, Didovic S, Brauckmann D, Rani M, Agrawal H, Schade FU, Zhang Y, Flohé SB.

J Immunol. 2011 Jan 15;186(2):977-86. doi: 10.4049/jimmunol.1001147. Epub 2010 Dec 15.

3.

Isolated closed minor-muscle injury of the lower leg did not cause an obvious systemic immune response.

Schmitz D, Bangen JM, Herborn CU, Husain B, Lendemans S, Flohé SB, Metz KA, Schade FU, Taeger G, Oberbeck JR, Kobbe P, Waydhas C, Flohé S.

Inflamm Res. 2010 Feb;59(2):141-9. doi: 10.1007/s00011-009-0081-z. Epub 2009 Aug 26.

PMID:
19707856
4.

Invited review: deterioration of the immune system after trauma: signals and cellular mechanisms.

Flohé SB, Flohé S, Schade FU.

Innate Immun. 2008 Dec;14(6):333-44. doi: 10.1177/1753425908100016. Review.

PMID:
19039057
5.

Microcirculatory alterations of hepatic and mesenteric microcirculation in endotoxin tolerance.

Lendemans S, Peszko A, Oberbeck R, Schmitz D, Husain B, Burkhard M, Schade FU, Flohe S.

Shock. 2008 Feb;29(2):223-31.

PMID:
18386390
6.

Diversity of interferon gamma and granulocyte-macrophage colony-stimulating factor in restoring immune dysfunction of dendritic cells and macrophages during polymicrobial sepsis.

Flohé SB, Agrawal H, Flohé S, Rani M, Bangen JM, Schade FU.

Mol Med. 2008 May-Jun;14(5-6):247-56. doi: 10.2119/2007-00120.Flohe.

7.

Toll-like receptor 2 and 4 expression after severe injury is not involved in the dysregulation of the innate immune system.

Lendemans S, Kreuzfelder E, Rani M, Bayeeh E, Schade FU, Flohé SB, Waydhas C, Flohé S.

J Trauma. 2007 Oct;63(4):740-6.

PMID:
18089999
8.

Immune response of severely injured patients--influence of surgical intervention and therapeutic impact.

Flohé S, Flohé SB, Schade FU, Waydhas C.

Langenbecks Arch Surg. 2007 Sep;392(5):639-48. Epub 2007 Jun 29. Review.

PMID:
17605036
9.

Diverse regulatory activity of human heat shock proteins 60 and 70 on endotoxin-induced inflammation.

Bangen JM, Schade FU, Flohé SB.

Biochem Biophys Res Commun. 2007 Aug 3;359(3):709-15. Epub 2007 May 30.

PMID:
17553457
10.

Origin of immunomodulation after soft tissue trauma: potential involvement of extracellular heat-shock proteins.

Flohé SB, Bangen JM, Flohé S, Agrawal H, Bergmann K, Schade FU.

Shock. 2007 May;27(5):494-502.

PMID:
17438454
11.

Regulation of cytokine synthesis in cardiac surgery: Role of extracorporeal circuit and humoral mediators in vivo and in vitro.

Börgermann J, Flohé S, Scheubel RJ, Kuss O, Simm A, Schade FU, Friedrich I.

Inflamm Res. 2007 Mar;56(3):126-32.

PMID:
17406810
13.

Haemorrhagic shock in mice--intracellular signalling and immunomodulation of peritoneal macrophages' LPS response.

Rani M, Husain B, Lendemans S, Schade FU, Flohé S.

Immunobiology. 2006;211(9):711-9. Epub 2006 Jun 13.

PMID:
17015146
14.

GM-CSF priming of human monocytes is dependent on ERK1/2 activation.

Lendemans S, Rani M, Selbach C, Kreuzfelder E, Schade FU, Flohé S.

J Endotoxin Res. 2006;12(1):10-20.

PMID:
16420740
15.

Dendritic cells during polymicrobial sepsis rapidly mature but fail to initiate a protective Th1-type immune response.

Flohé SB, Agrawal H, Schmitz D, Gertz M, Flohé S, Schade FU.

J Leukoc Biol. 2006 Mar;79(3):473-81. Epub 2005 Dec 19.

PMID:
16365154
16.

In vivo effects of hypothermia on the microcirculation during extracorporeal circulation.

Kamler M, Goedeke J, Pizanis N, Milekhin V, Schade FU, Jakob H.

Eur J Cardiothorac Surg. 2005 Aug;28(2):259-65.

PMID:
15951194
17.

GM-CSF counteracts hemorrhage-induced suppression of cytokine-producing capacity.

Husain B, Lendemans S, Ackermann M, Wendel A, Schade FU, Flohé S.

Inflamm Res. 2004 Jan;53(1):13-21. Epub 2004 Jan 1.

PMID:
15021976
18.

Influence of surgical intervention in the immune response of severely injured patients.

Flohé S, Lendemans S, Schade FU, Kreuzfelder E, Waydhas C.

Intensive Care Med. 2004 Jan;30(1):96-102. Epub 2003 Nov 7.

PMID:
14605804
19.

Effect of granulocyte-macrophage colony-stimulating factor on the immune response of circulating monocytes after severe trauma.

Flohé S, Lendemans S, Selbach C, Waydhas C, Ackermann M, Schade FU, Kreuzfelder E.

Crit Care Med. 2003 Oct;31(10):2462-9.

PMID:
14530752
20.

[Endotoxin tolerance and hemorrhagic shock in rats].

Ackermann MN, Reuter M, Flohé S, Flach R, Bahrami S, Schlag G, Schade FU.

Langenbecks Arch Chir Suppl Kongressbd. 1998;115(Suppl I):181-4. German.

PMID:
14518238
21.

[Transfusion of plasma of endotoxin tolerant rats improves survival of hemorrhagic shock in the rat model].

Reuter M, Bahrami S, Ackermann M, Obertacke U, Schade FU, Schlag G.

Langenbecks Arch Chir Suppl Kongressbd. 1998;115(Suppl I):177-80. German.

PMID:
14518237
22.

[Modification of immune response after polytrauma and cardiopulmonary bypass by hematopoietic growth factors].

Flohé S, Börgermann J, Kreutzfelder E, Lim L, Flach R, Majetschak M, Obertacke U, Schade FU.

Langenbecks Arch Chir Suppl Kongressbd. 1998;115(Suppl I):169-72. German.

PMID:
14518235
23.

Endotoxin tolerance in rats: influence on LPS-induced changes in excretory liver function.

Domínguez Fernández E, Flohé S, Siemers F, Nau M, Schade FU.

Inflamm Res. 2002 Oct;51(10):500-5.

PMID:
12477079
24.

Tumor necrosis factor gene polymorphisms, leukocyte function, and sepsis susceptibility in blunt trauma patients.

Majetschak M, Obertacke U, Schade FU, Bardenheuer M, Voggenreiter G, Bloemeke B, Heesen M.

Clin Diagn Lab Immunol. 2002 Nov;9(6):1205-11.

25.

Induction of endotoxin tolerance improves lung function after warm ischemia in dogs.

Friedrich I, Spillner J, Lu EX, Barnscheidt M, Kuss O, Sablotzki A, Schade FU, Borgermann J.

Am J Physiol Lung Cell Mol Physiol. 2003 Jan;284(1):L224-31. Epub 2002 Sep 20.

26.

Tumor necrosis factor-alpha production in whole blood after cardiopulmonary bypass: downregulation caused by circulating cytokine-inhibitory activities.

Börgermann J, Friedrich I, Flohé S, Spillner J, Majetschak M, Kuss O, Sablotzki A, Feldt T, Reidemeister JC, Schade FU.

J Thorac Cardiovasc Surg. 2002 Sep;124(3):608-17.

27.

Effects of antimicrobial agents on spontaneous and endotoxin-induced cytokine release of human peripheral blood mononuclear cells.

Krehmeier U, Bardenheuer M, Voggenreiter G, Obertacke U, Schade FU, Majetschak M.

J Infect Chemother. 2002 Jun;8(2):194-7.

PMID:
12111578
28.

The interleukin-6 G(-174)C polymorphism and the ex vivo interleukin-6 response to endotoxin in severely injured blunt trauma patients.

Heesen M, Obertacke U, Schade FU, Bloemeke B, Majetschak M.

Eur Cytokine Netw. 2002 Jan-Mar;13(1):72-7.

29.

Effects of endotoxin tolerance on liver function after hepatic ischemia/reperfusion injury in the rat.

Domínguez FE, Siemers F, Flohé S, Nau M, Schade FU.

Crit Care Med. 2002 Jan;30(1):165-70.

PMID:
11902258
30.

Cytokine synthesis in the liver of endotoxin-tolerant and normal rats during hemorrhagic shock.

Ackermann M, Reuter M, Flohé S, Bahrami S, Redl H, Schade FU.

J Endotoxin Res. 2001;7(2):105-12.

PMID:
11521090
31.

Cytosolic protein ubiquitylation in normal and endotoxin stimulated human peripheral blood mononuclear cells.

Majetschak M, Suciu DM, Häsler K, Obertacke U, Schade FU, Jennissen HP.

J Endotoxin Res. 2000;6(6):483-8.

PMID:
11521075
32.
33.

Endotoxin tolerance protects against local hepatic ischemia/reperfusion injury in the rat.

Fernández ED, Flohé S, Siemers F, Nau M, Ackermann M, Ruwe M, Schade FU.

J Endotoxin Res. 2000;6(4):321-8.

PMID:
11521053
34.

[Mediator modulation in infection and multiple organ failure].

Majetschak M, Obertacke U, Waydhas C, Nast-Kolb D, Schade FU.

Unfallchirurg. 2000 Oct;103(10):903-7. Review. German. No abstract available.

PMID:
11098752
35.

Sublethal hemorrhagic shock reduces tumor necrosis factor-alpha-producing capacity in different cell compartments.

Flohé S, Ackermann M, Reuter M, Nast-Kolb D, Schade FU.

Eur Cytokine Netw. 2000 Sep;11(3):420-6.

36.

Immunosuppression with FK506 increases bone induction in demineralized isogeneic and xenogeneic bone matrix in the rat.

Voggenreiter G, Assenmacher S, Kreuzfelder E, Wolf M, Kim MR, Nast-Kolb D, Schade FU.

J Bone Miner Res. 2000 Sep;15(9):1825-34.

37.
38.
39.

Sex differences in posttraumatic cytokine release of endotoxin-stimulated whole blood: relationship to the development of severe sepsis.

Majetschak M, Christensen B, Obertacke U, Waydhas C, Schindler AE, Nast-Kolb D, Schade FU.

J Trauma. 2000 May;48(5):832-9; discussion 839-40.

PMID:
10823526
40.

Endotoxin and ischemic preconditioning: TNF-alpha concentration and myocardial infarct development in rabbits.

Belosjorow S, Schulz R, Dörge H, Schade FU, Heusch G.

Am J Physiol. 1999 Dec;277(6):H2470-5. doi: 10.1152/ajpheart.1999.277.6.H2470.

PMID:
10600870
41.

Endotoxin tolerance in rats: expression of TNF-alpha, IL-6, IL-10, VCAM-1 AND HSP 70 in lung and liver during endotoxin shock.

Flohé S, Dominguez Fernández E, Ackermann M, Hirsch T, Börgermann J, Schade FU.

Cytokine. 1999 Oct;11(10):796-804.

PMID:
10525319
42.

Influence of granulocyte-macrophage colony-stimulating factor (GM-CSF) on whole blood endotoxin responsiveness following trauma, cardiopulmonary bypass, and severe sepsis.

Flohé S, Börgermann J, Domínguez FE, Majetschak M, Lim L, Kreuzfelder E, Obertacke U, Nast-Kolb D, Schade FU.

Shock. 1999 Jul;12(1):17-24.

PMID:
10468047
43.

Relation of a TNF gene polymorphism to severe sepsis in trauma patients.

Majetschak M, Flohé S, Obertacke U, Schröder J, Staubach K, Nast-Kolb D, Schade FU, Stüber F.

Ann Surg. 1999 Aug;230(2):207-14.

44.

Relation of ex vivo stimulated blood cytokine synthesis to post-traumatic sepsis.

Flach R, Majetschak M, Heukamp T, Jennissen V, Flohé S, Börgermann J, Obertacke U, Schade FU.

Cytokine. 1999 Feb;11(2):173-8.

PMID:
10089141
45.

The extent of traumatic damage determines a graded depression of the endotoxin responsiveness of peripheral blood mononuclear cells from patients with blunt injuries.

Majetschak M, Flach R, Kreuzfelder E, Jennissen V, Heukamp T, Neudeck F, Schmit-Neuerburg KP, Obertacke U, Schade FU.

Crit Care Med. 1999 Feb;27(2):313-8.

PMID:
10075055
46.

Local and systemic reactions after lung contusion: an experimental study in the pig.

Obertacke U, Neudeck F, Majetschak M, Hellinger A, Kleinschmidt C, Schade FU, Høgasen K, Jochum M, Strohmeier W, Thurnher M, Redl H, Schlag G.

Shock. 1998 Jul;10(1):7-12.

PMID:
9688084
47.

Analysis of intragraft cytokine expression during early reperfusion after liver transplantation using semi-quantitative RT-PCR.

Flach R, Speidel N, Flohé S, Börgermann J, Dresen IG, Erhard J, Schade FU.

Cytokine. 1998 Jun;10(6):445-51.

PMID:
9632531
48.

Expression of HSP 70 as a potential prognostic marker for acute rejection in human liver transplantation.

Flohé S, Speidel N, Flach R, Lange R, Erhard J, Schade FU.

Transpl Int. 1998;11(2):89-94.

PMID:
9561674
49.

Regulation of whole blood tumor necrosis factor production upon endotoxin stimulation after severe blunt trauma.

Majetschak M, Flach R, Heukamp T, Jennissen V, Obertacke U, Neudeck F, Schmit-Neuerburg KP, Schade FU.

J Trauma. 1997 Dec;43(6):880-7.

PMID:
9420099
50.

Pattern of soluble TNF receptors I and II in sepsis.

Schröder J, Stüber F, Gallati H, Schade FU, Kremer B.

Infection. 1995 May-Jun;23(3):143-8.

PMID:
7499002

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