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Items: 7

1.

Noncompetitive inhibitors of TNFR1 probe conformational activation states.

Lo CH, Schaaf TM, Grant BD, Lim CK, Bawaskar P, Aldrich CC, Thomas DD, Sachs JN.

Sci Signal. 2019 Jul 30;12(592). pii: eaav5637. doi: 10.1126/scisignal.aav5637.

PMID:
31363069
2.

Red-Shifted FRET Biosensors for High-Throughput Fluorescence Lifetime Screening.

Schaaf TM, Li A, Grant BD, Peterson K, Yuen S, Bawaskar P, Kleinboehl E, Li J, Thomas DD, Gillispie GD.

Biosensors (Basel). 2018 Oct 24;8(4). pii: E99. doi: 10.3390/bios8040099.

3.

Targeting protein-protein interactions for therapeutic discovery via FRET-based high-throughput screening in living cells.

Stroik DR, Yuen SL, Janicek KA, Schaaf TM, Li J, Ceholski DK, Hajjar RJ, Cornea RL, Thomas DD.

Sci Rep. 2018 Aug 22;8(1):12560. doi: 10.1038/s41598-018-29685-z.

4.

An Innovative High-Throughput Screening Approach for Discovery of Small Molecules That Inhibit TNF Receptors.

Lo CH, Vunnam N, Lewis AK, Chiu TL, Brummel BE, Schaaf TM, Grant BD, Bawaskar P, Thomas DD, Sachs JN.

SLAS Discov. 2017 Sep;22(8):950-961. doi: 10.1177/2472555217706478. Epub 2017 May 22.

5.

High-Throughput Spectral and Lifetime-Based FRET Screening in Living Cells to Identify Small-Molecule Effectors of SERCA.

Schaaf TM, Peterson KC, Grant BD, Bawaskar P, Yuen S, Li J, Muretta JM, Gillispie GD, Thomas DD.

SLAS Discov. 2017 Mar;22(3):262-273. doi: 10.1177/1087057116680151. Epub 2016 Dec 13.

6.

Spectral Unmixing Plate Reader: High-Throughput, High-Precision FRET Assays in Living Cells.

Schaaf TM, Peterson KC, Grant BD, Thomas DD, Gillispie GD.

SLAS Discov. 2017 Mar;22(3):250-261. doi: 10.1177/1087057116679637. Epub 2016 Nov 23.

7.

Discovery of enzyme modulators via high-throughput time-resolved FRET in living cells.

Gruber SJ, Cornea RL, Li J, Peterson KC, Schaaf TM, Gillispie GD, Dahl R, Zsebo KM, Robia SL, Thomas DD.

J Biomol Screen. 2014 Feb;19(2):215-22. doi: 10.1177/1087057113510740.

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