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Items: 35


Lobular neoplasia and invasive lobular breast cancer: Inter-observer agreement for histological grading and subclassification.

Schaumann N, Raap M, Hinze L, Rieger L, Schürch CM, Antonopoulos W, Avril S, Krech T, Dämmrich M, Kayser G, Puls F, Länger F, Tinguely M, Kreipe H, Christgen M.

Pathol Res Pract. 2019 Nov;215(11):152611. doi: 10.1016/j.prp.2019.152611. Epub 2019 Aug 20.


Modeling hematopoietic disorders in zebrafish.

Konantz M, Schürch C, Hanns P, Müller JS, Sauteur L, Lengerke C.

Dis Model Mech. 2019 Sep 6;12(9). pii: dmm040360. doi: 10.1242/dmm.040360. Review.


CARving up colorectal cancer organoids in vitro.

Schürch CM.

Genes Immun. 2019 May 20. doi: 10.1038/s41435-019-0079-7. [Epub ahead of print] No abstract available.


A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma.

Lytle NK, Ferguson LP, Rajbhandari N, Gilroy K, Fox RG, Deshpande A, Schürch CM, Hamilton M, Robertson N, Lin W, Noel P, Wartenberg M, Zlobec I, Eichmann M, Galván JA, Karamitopoulou E, Gilderman T, Esparza LA, Shima Y, Spahn P, French R, Lewis NE, Fisch KM, Sasik R, Rosenthal SB, Kritzik M, Von Hoff D, Han H, Ideker T, Deshpande AJ, Lowy AM, Adams PD, Reya T.

Cell. 2019 Apr 18;177(3):572-586.e22. doi: 10.1016/j.cell.2019.03.010. Epub 2019 Apr 4.


Targeting CD47 in Anaplastic Thyroid Carcinoma Enhances Tumor Phagocytosis by Macrophages and Is a Promising Therapeutic Strategy.

Schürch CM, Roelli MA, Forster S, Wasmer MH, Brühl F, Maire RS, Di Pancrazio S, Ruepp MD, Giger R, Perren A, Schmitt AM, Krebs P, Charles RP, Dettmer MS.

Thyroid. 2019 Jul;29(7):979-992. doi: 10.1089/thy.2018.0555. Epub 2019 May 10.


Regulation of glioma cell invasion by 3q26 gene products PIK3CA, SOX2 and OPA1.

Schaefer T, Ramadoss A, Leu S, Tintignac L, Tostado C, Bink A, Schürch C, Müller J, Schärer J, Moffa G, Demougin P, Moes S, Stippich C, Falbo S, Neddersen H, Bucher H, Frank S, Jenö P, Lengerke C, Ritz MF, Mariani L, Boulay JL.

Brain Pathol. 2019 May;29(3):336-350. doi: 10.1111/bpa.12670. Epub 2018 Dec 21.


Therapeutic Antibodies for Myeloid Neoplasms-Current Developments and Future Directions.

Schürch CM.

Front Oncol. 2018 May 18;8:152. doi: 10.3389/fonc.2018.00152. eCollection 2018. Review.


The "don't eat me" signal CD47 is a novel diagnostic biomarker and potential therapeutic target for diffuse malignant mesothelioma.

Schürch CM, Forster S, Brühl F, Yang SH, Felley-Bosco E, Hewer E.

Oncoimmunology. 2017 Sep 21;7(1):e1373235. doi: 10.1080/2162402X.2017.1373235. eCollection 2017.


How mechanisms explain interfield cooperation: biological-chemical study of plant growth hormones in Utrecht and Pasadena, 1930-1938.

Schürch C.

Hist Philos Life Sci. 2017 Sep;39(3):16. doi: 10.1007/s40656-017-0144-3. Epub 2017 Jul 19.


Tumor Heterogeneity in Lymphomas: A Different Breed.

Schürch CM, Federmann B, Quintanilla-Martinez L, Fend F.

Pathobiology. 2018;85(1-2):130-145. doi: 10.1159/000475530. Epub 2017 Jul 19. Review.


Innate immunity restricts Citrobacter rodentium A/E pathogenesis initiation to an early window of opportunity.

Buschor S, Cuenca M, Uster SS, Schären OP, Balmer ML, Terrazos MA, Schürch CM, Hapfelmeier S.

PLoS Pathog. 2017 Jun 29;13(6):e1006476. doi: 10.1371/journal.ppat.1006476. eCollection 2017 Jun.


The Multi-kinase Inhibitor Debio 0617B Reduces Maintenance and Self-renewal of Primary Human AML CD34+ Stem/Progenitor Cells.

Murone M, Radpour R, Attinger A, Chessex AV, Huguenin AL, Schürch CM, Banz Y, Sengupta S, Aguet M, Rigotti S, Bachhav Y, Massière F, Ramachandra M, McAllister A, Riether C.

Mol Cancer Ther. 2017 Aug;16(8):1497-1510. doi: 10.1158/1535-7163.MCT-16-0889. Epub 2017 May 3.


Functional Intestinal Bile Acid 7α-Dehydroxylation by Clostridium scindens Associated with Protection from Clostridium difficile Infection in a Gnotobiotic Mouse Model.

Studer N, Desharnais L, Beutler M, Brugiroux S, Terrazos MA, Menin L, Schürch CM, McCoy KD, Kuehne SA, Minton NP, Stecher B, Bernier-Latmani R, Hapfelmeier S.

Front Cell Infect Microbiol. 2016 Dec 20;6:191. doi: 10.3389/fcimb.2016.00191. eCollection 2016.


CD70/CD27 signaling promotes blast stemness and is a viable therapeutic target in acute myeloid leukemia.

Riether C, Schürch CM, Bührer ED, Hinterbrandner M, Huguenin AL, Hoepner S, Zlobec I, Pabst T, Radpour R, Ochsenbein AF.

J Exp Med. 2017 Feb;214(2):359-380. doi: 10.1084/jem.20152008. Epub 2016 Dec 28.


Tyrosine kinase inhibitor-induced CD70 expression mediates drug resistance in leukemia stem cells by activating Wnt signaling.

Riether C, Schürch CM, Flury C, Hinterbrandner M, Drück L, Huguenin AL, Baerlocher GM, Radpour R, Ochsenbein AF.

Sci Transl Med. 2015 Jul 29;7(298):298ra119. doi: 10.1126/scitranslmed.aab1740.


IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms.

Mager LF, Riether C, Schürch CM, Banz Y, Wasmer MH, Stuber R, Theocharides AP, Li X, Xia Y, Saito H, Nakae S, Baerlocher GM, Manz MG, McCoy KD, Macpherson AJ, Ochsenbein AF, Beutler B, Krebs P.

J Clin Invest. 2015 Jul 1;125(7):2579-91. doi: 10.1172/JCI77347. Epub 2015 May 26.


CD47 protein expression in acute myeloid leukemia: A tissue microarray-based analysis.

Galli S, Zlobec I, Schürch C, Perren A, Ochsenbein AF, Banz Y.

Leuk Res. 2015 Jul;39(7):749-56. doi: 10.1016/j.leukres.2015.04.007. Epub 2015 Apr 20.


Blocking programmed cell death 1 in combination with adoptive cytotoxic T-cell transfer eradicates chronic myelogenous leukemia stem cells.

Riether C, Gschwend T, Huguenin AL, Schürch CM, Ochsenbein AF.

Leukemia. 2015 Aug;29(8):1781-5. doi: 10.1038/leu.2015.26. Epub 2015 Feb 4. No abstract available.


Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling.

Balmer ML, Schürch CM, Saito Y, Geuking MB, Li H, Cuenca M, Kovtonyuk LV, McCoy KD, Hapfelmeier S, Ochsenbein AF, Manz MG, Slack E, Macpherson AJ.

J Immunol. 2014 Nov 15;193(10):5273-83. doi: 10.4049/jimmunol.1400762. Epub 2014 Oct 10.


Regulation of hematopoietic and leukemic stem cells by the immune system.

Riether C, Schürch CM, Ochsenbein AF.

Cell Death Differ. 2015 Feb;22(2):187-98. doi: 10.1038/cdd.2014.89. Epub 2014 Jul 4. Review.


Cytotoxic CD8+ T cells stimulate hematopoietic progenitors by promoting cytokine release from bone marrow mesenchymal stromal cells.

Schürch CM, Riether C, Ochsenbein AF.

Cell Stem Cell. 2014 Apr 3;14(4):460-72. doi: 10.1016/j.stem.2014.01.002. Epub 2014 Feb 20.


TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance.

Weber B, Schuster S, Zysset D, Rihs S, Dickgreber N, Schürch C, Riether C, Siegrist M, Schneider C, Pawelski H, Gurzeler U, Ziltener P, Genitsch V, Tacchini-Cottier F, Ochsenbein A, Hofstetter W, Kopf M, Kaufmann T, Oxenius A, Reith W, Saurer L, Mueller C.

PLoS Pathog. 2014 Jan;10(1):e1003900. doi: 10.1371/journal.ppat.1003900. Epub 2014 Jan 16.


Dendritic cell-based immunotherapy for myeloid leukemias.

Schürch CM, Riether C, Ochsenbein AF.

Front Immunol. 2013 Dec 31;4:496. doi: 10.3389/fimmu.2013.00496. Review.


Interferons in hematopoiesis and leukemia.

Schürch CM, Riether C, Ochsenbein AF.

Oncoimmunology. 2013 Jun 1;2(6):e24572. Epub 2013 Apr 16.


"Leiomyomatoid angiomatous neuroendocrine tumor" (LANT) of the pituitary reflects idiosyncratic angiogenesis in adenomas of the gonadotroph cell lineage.

Schürch C, Birrer M, Estella I, Kappeler A, Hewer E, Vajtai I.

Pathol Res Pract. 2013 Mar;209(3):155-60. doi: 10.1016/j.prp.2013.01.003. Epub 2013 Feb 15.


Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-γ.

Schürch C, Riether C, Amrein MA, Ochsenbein AF.

J Exp Med. 2013 Mar 11;210(3):605-21. doi: 10.1084/jem.20121229. Epub 2013 Feb 11.


From "magic bullets" to specific cancer immunotherapy.

Riether C, Schürch C, Ochsenbein AF.

Swiss Med Wkly. 2013 Jan 23;143:w13734. doi: 10.4414/smw.2013.13734. eCollection 2013. Review.


Modulating CD27 signaling to treat cancer.

Riether C, Schürch C, Ochsenbein AF.

Oncoimmunology. 2012 Dec 1;1(9):1604-1606.


CD27 signaling increases the frequency of regulatory T cells and promotes tumor growth.

Claus C, Riether C, Schürch C, Matter MS, Hilmenyuk T, Ochsenbein AF.

Cancer Res. 2012 Jul 15;72(14):3664-76. doi: 10.1158/0008-5472.CAN-11-2791. Epub 2012 May 24.


CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression.

Schürch C, Riether C, Matter MS, Tzankov A, Ochsenbein AF.

J Clin Invest. 2012 Feb;122(2):624-38. doi: 10.1172/JCI45977. Epub 2012 Jan 9.


Destruction of lymphoid organ architecture and hepatitis caused by CD4+ T cells.

Matter MS, Hilmenyuk T, Claus C, Marone R, Schürch C, Tinguely M, Terracciano L, Luther SA, Ochsenbein AF.

PLoS One. 2011;6(9):e24772. doi: 10.1371/journal.pone.0024772. Epub 2011 Sep 23.


Chronic myelogenous leukemia maintains specific CD8(+) T cells through IL-7 signaling.

Mumprecht S, Schürch C, Scherrer S, Claus C, Ochsenbein AF.

Eur J Immunol. 2010 Oct;40(10):2720-30. doi: 10.1002/eji.201040404.


Programmed death 1 signaling on chronic myeloid leukemia-specific T cells results in T-cell exhaustion and disease progression.

Mumprecht S, Schürch C, Schwaller J, Solenthaler M, Ochsenbein AF.

Blood. 2009 Aug 20;114(8):1528-36. doi: 10.1182/blood-2008-09-179697. Epub 2009 May 6.


Defective homing and impaired induction of cytotoxic T cells by BCR/ABL-expressing dendritic cells.

Mumprecht S, Claus C, Schürch C, Pavelic V, Matter MS, Ochsenbein AF.

Blood. 2009 May 7;113(19):4681-9. doi: 10.1182/blood-2008-05-156471. Epub 2009 Feb 27.


Prevention of brain injury by the nonbacteriolytic antibiotic daptomycin in experimental pneumococcal meningitis.

Grandgirard D, Schürch C, Cottagnoud P, Leib SL.

Antimicrob Agents Chemother. 2007 Jun;51(6):2173-8. Epub 2007 Mar 19.

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