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Items: 14

1.

Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformations.

Kraft K, Magg A, Heinrich V, Riemenschneider C, Schöpflin R, Markowski J, Ibrahim DM, Acuna-Hidalgo R, Despang A, Andrey G, Wittler L, Timmermann B, Vingron M, Mundlos S.

Nat Cell Biol. 2019 Mar;21(3):305-310. doi: 10.1038/s41556-019-0273-x. Epub 2019 Feb 11.

PMID:
30742094
2.

Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis.

Kragesteen BK, Spielmann M, Paliou C, Heinrich V, Schöpflin R, Esposito A, Annunziatella C, Bianco S, Chiariello AM, Jerković I, Harabula I, Guckelberger P, Pechstein M, Wittler L, Chan WL, Franke M, Lupiáñez DG, Kraft K, Timmermann B, Vingron M, Visel A, Nicodemi M, Mundlos S, Andrey G.

Nat Genet. 2018 Oct;50(10):1463-1473. doi: 10.1038/s41588-018-0221-x. Epub 2018 Sep 27.

PMID:
30262816
3.

Polymer physics predicts the effects of structural variants on chromatin architecture.

Bianco S, Lupiáñez DG, Chiariello AM, Annunziatella C, Kraft K, Schöpflin R, Wittler L, Andrey G, Vingron M, Pombo A, Mundlos S, Nicodemi M.

Nat Genet. 2018 May;50(5):662-667. doi: 10.1038/s41588-018-0098-8. Epub 2018 Apr 16.

PMID:
29662163
4.

Genomic dissection of enhancers uncovers principles of combinatorial regulation and cell type-specific wiring of enhancer-promoter contacts.

Thormann V, Rothkegel MC, Schöpflin R, Glaser LV, Djuric P, Li N, Chung HR, Schwahn K, Vingron M, Meijsing SH.

Nucleic Acids Res. 2018 Apr 6;46(6):3258. doi: 10.1093/nar/gky122. No abstract available.

5.

Genomic dissection of enhancers uncovers principles of combinatorial regulation and cell type-specific wiring of enhancer-promoter contacts.

Thormann V, Rothkegel MC, Schöpflin R, Glaser LV, Djuric P, Li N, Chung HR, Schwahn K, Vingron M, Meijsing SH.

Nucleic Acids Res. 2018 Apr 6;46(6):2868-2882. doi: 10.1093/nar/gky051.

6.

Characterization of hundreds of regulatory landscapes in developing limbs reveals two regimes of chromatin folding.

Andrey G, Schöpflin R, Jerković I, Heinrich V, Ibrahim DM, Paliou C, Hochradel M, Timmermann B, Haas S, Vingron M, Mundlos S.

Genome Res. 2017 Feb;27(2):223-233. doi: 10.1101/gr.213066.116. Epub 2016 Dec 6.

7.

Role of the chromatin landscape and sequence in determining cell type-specific genomic glucocorticoid receptor binding and gene regulation.

Love MI, Huska MR, Jurk M, Schöpflin R, Starick SR, Schwahn K, Cooper SB, Yamamoto KR, Thomas-Chollier M, Vingron M, Meijsing SH.

Nucleic Acids Res. 2017 Feb 28;45(4):1805-1819. doi: 10.1093/nar/gkw1163.

8.

Formation of new chromatin domains determines pathogenicity of genomic duplications.

Franke M, Ibrahim DM, Andrey G, Schwarzer W, Heinrich V, Schöpflin R, Kraft K, Kempfer R, Jerković I, Chan WL, Spielmann M, Timmermann B, Wittler L, Kurth I, Cambiaso P, Zuffardi O, Houge G, Lambie L, Brancati F, Pombo A, Vingron M, Spitz F, Mundlos S.

Nature. 2016 Oct 13;538(7624):265-269. doi: 10.1038/nature19800. Epub 2016 Oct 5.

PMID:
27706140
9.

Changing chromatin fiber conformation by nucleosome repositioning.

Müller O, Kepper N, Schöpflin R, Ettig R, Rippe K, Wedemann G.

Biophys J. 2014 Nov 4;107(9):2141-50. doi: 10.1016/j.bpj.2014.09.026.

10.

Modeling nucleosome position distributions from experimental nucleosome positioning maps.

Schöpflin R, Teif VB, Müller O, Weinberg C, Rippe K, Wedemann G.

Bioinformatics. 2013 Oct 1;29(19):2380-6. doi: 10.1093/bioinformatics/btt404. Epub 2013 Jul 11.

PMID:
23846748
11.

Single-drop optimization of protein crystallization.

Meyer A, Dierks K, Hilterhaus D, Klupsch T, Mühlig P, Kleesiek J, Schöpflin R, Einspahr H, Hilgenfeld R, Betzel C.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Aug 1;68(Pt 8):994-8. doi: 10.1107/S1744309112024074. Epub 2012 Jul 31.

12.

Probing the elasticity of DNA on short length scales by modeling supercoiling under tension.

Schöpflin R, Brutzer H, Müller O, Seidel R, Wedemann G.

Biophys J. 2012 Jul 18;103(2):323-30. doi: 10.1016/j.bpj.2012.05.050. Epub 2012 Jul 17.

13.

DNA-DNA interactions in tight supercoils are described by a small effective charge density.

Maffeo C, Schöpflin R, Brutzer H, Stehr R, Aksimentiev A, Wedemann G, Seidel R.

Phys Rev Lett. 2010 Oct 8;105(15):158101. Epub 2010 Oct 4.

14.

Exploring the conformational space of chromatin fibers and their stability by numerical dynamic phase diagrams.

Stehr R, Schöpflin R, Ettig R, Kepper N, Rippe K, Wedemann G.

Biophys J. 2010 Mar 17;98(6):1028-37. doi: 10.1016/j.bpj.2009.11.040.

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