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Items: 1 to 50 of 53

1.

RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas.

Wirthschaft P, Bode J, Soni H, Dietrich F, Krüwel T, Fischer B, Knobbe-Thomsen CB, Rossetti G, Hentschel A, Mack N, Schönig K, Breckwoldt MO, Schmandke A, Pusch S, Medenbach J, Bendszus M, Schwab ME, von Deimling A, Kool M, Herold-Mende C, Reifenberger G, Ahrends R, Tews B.

Acta Neuropathol. 2019 May 6. doi: 10.1007/s00401-019-02021-z. [Epub ahead of print]

PMID:
31062076
2.

Alcohol reduces muscle fatigue through atomistic interactions with nicotinic receptors.

Noori HR, Mücksch C, Vengeliene V, Schönig K, Takahashi TT, Mukhtasimova N, Bagher Oskouei M, Mosqueira M, Bartsch D, Fink R, Urbassek HM, Spanagel R, Sine SM.

Commun Biol. 2018 Oct 3;1:159. doi: 10.1038/s42003-018-0157-9. eCollection 2018.

3.

Targeted overexpression of CRH receptor subtype 1 in central amygdala neurons: effect on alcohol-seeking behavior.

Broccoli L, Uhrig S, von Jonquieres G, Schönig K, Bartsch D, Justice NJ, Spanagel R, Sommer WH, Klugmann M, Hansson AC.

Psychopharmacology (Berl). 2018 Jun;235(6):1821-1833. doi: 10.1007/s00213-018-4908-6. Epub 2018 Apr 26.

PMID:
29700576
4.

Forebrain-specific, conditional silencing of Staufen2 alters synaptic plasticity, learning, and memory in rats.

Berger SM, Fernández-Lamo I, Schönig K, Fernández Moya SM, Ehses J, Schieweck R, Clementi S, Enkel T, Grothe S, von Bohlen Und Halbach O, Segura I, Delgado-García JM, Gruart A, Kiebler MA, Bartsch D.

Genome Biol. 2017 Nov 17;18(1):222. doi: 10.1186/s13059-017-1350-8.

5.

Inducible knockdown of procollagen I protects mice from liver fibrosis and leads to dysregulated matrix genes and attenuated inflammation.

Molokanova O, Schönig K, Weng SY, Wang X, Bros M, Diken M, Ohngemach S, Karsdal M, Strand D, Nikolaev A, Eshkind L, Schuppan D.

Matrix Biol. 2018 Mar;66:34-49. doi: 10.1016/j.matbio.2017.11.002. Epub 2017 Nov 6.

PMID:
29122677
6.

Type-1 astrocyte-like stem cells harboring Cacna1d gene deletion exhibit reduced proliferation and decreased neuronal fate choice.

Völkening B, Schönig K, Kronenberg G, Bartsch D, Weber T.

Hippocampus. 2018 Feb;28(2):97-107. doi: 10.1002/hipo.22811. Epub 2017 Nov 22.

PMID:
29116659
7.

Deletion of psychiatric risk gene Cacna1c impairs hippocampal neurogenesis in cell-autonomous fashion.

Völkening B, Schönig K, Kronenberg G, Bartsch D, Weber T.

Glia. 2017 May;65(5):817-827. doi: 10.1002/glia.23128. Epub 2017 Feb 23.

PMID:
28230278
8.

Differential Roles for L-Type Calcium Channel Subtypes in Alcohol Dependence.

Uhrig S, Vandael D, Marcantoni A, Dedic N, Bilbao A, Vogt MA, Hirth N, Broccoli L, Bernardi RE, Schönig K, Gass P, Bartsch D, Spanagel R, Deussing JM, Sommer WH, Carbone E, Hansson AC.

Neuropsychopharmacology. 2017 Apr;42(5):1058-1069. doi: 10.1038/npp.2016.266. Epub 2016 Dec 1.

9.

Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR.

Haeussler M, Schönig K, Eckert H, Eschstruth A, Mianné J, Renaud JB, Schneider-Maunoury S, Shkumatava A, Teboul L, Kent J, Joly JS, Concordet JP.

Genome Biol. 2016 Jul 5;17(1):148. doi: 10.1186/s13059-016-1012-2.

10.

mTOR inhibitor reverses autistic-like social deficit behaviours in adult rats with both Tsc2 haploinsufficiency and developmental status epilepticus.

Schneider M, de Vries PJ, Schönig K, Rößner V, Waltereit R.

Eur Arch Psychiatry Clin Neurosci. 2017 Aug;267(5):455-463. doi: 10.1007/s00406-016-0703-8. Epub 2016 Jun 4.

PMID:
27263037
11.

Quantitative performance characterization of three-dimensional noncontact fluorescence molecular tomography.

Favicchio R, Psycharakis S, Schönig K, Bartsch D, Mamalaki C, Papamatheakis J, Ripoll J, Zacharakis G.

J Biomed Opt. 2016 Feb;21(2):26009. doi: 10.1117/1.JBO.21.2.026009.

12.

Cell-type-specific tuning of Cav1.3 Ca(2+)-channels by a C-terminal automodulatory domain.

Scharinger A, Eckrich S, Vandael DH, Schönig K, Koschak A, Hecker D, Kaur G, Lee A, Sah A, Bartsch D, Benedetti B, Lieb A, Schick B, Singewald N, Sinnegger-Brauns MJ, Carbone E, Engel J, Striessnig J.

Front Cell Neurosci. 2015 Aug 24;9:309. doi: 10.3389/fncel.2015.00309. eCollection 2015.

13.

Losing Control: Excessive Alcohol Seeking after Selective Inactivation of Cue-Responsive Neurons in the Infralimbic Cortex.

Pfarr S, Meinhardt MW, Klee ML, Hansson AC, Vengeliene V, Schönig K, Bartsch D, Hope BT, Spanagel R, Sommer WH.

J Neurosci. 2015 Jul 29;35(30):10750-61. doi: 10.1523/JNEUROSCI.0684-15.2015.

14.

Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III.

Björkqvist J, de Maat S, Lewandrowski U, Di Gennaro A, Oschatz C, Schönig K, Nöthen MM, Drouet C, Braley H, Nolte MW, Sickmann A, Panousis C, Maas C, Renné T.

J Clin Invest. 2015 Aug 3;125(8):3132-46. doi: 10.1172/JCI77139. Epub 2015 Jul 20.

15.

A Limited Role for the Cell Cycle Regulator Cyclin A1 in Murine Leukemogenesis.

Bäumer N, Bäumer S, Haak M, Koschmieder S, Schönig K, Berdel WE, Müller-Tidow C.

PLoS One. 2015 Jun 16;10(6):e0129147. doi: 10.1371/journal.pone.0129147. eCollection 2015.

16.

γ-Aminobutyric A receptor (GABA(A)R) regulates aquaporin 4 expression in the subependymal zone: relevance to neural precursors and water exchange.

Li Y, Schmidt-Edelkraut U, Poetz F, Oliva I, Mandl C, Hölzl-Wenig G, Schönig K, Bartsch D, Ciccolini F.

J Biol Chem. 2015 Feb 13;290(7):4343-55. doi: 10.1074/jbc.M114.618686. Epub 2014 Dec 24.

17.

Postnatal subventricular zone progenitors switch their fate to generate neurons with distinct synaptic input patterns.

Ravi N, Li Z, Oettl LL, Bartsch D, Schönig K, Kelsch W.

Development. 2015 Jan 15;142(2):303-13. doi: 10.1242/dev.110767. Epub 2014 Dec 17.

18.

Global increase of p16INK4a in APC-deficient mouse liver drives clonal growth of p16INK4a-negative tumors.

Ueberham E, Glöckner P, Göhler C, Straub BK, Teupser D, Schönig K, Braeuning A, Höhn AK, Jerchow B, Birchmeier W, Gaunitz F, Arendt T, Sansom O, Gebhardt R, Ueberham U.

Mol Cancer Res. 2015 Feb;13(2):239-49. doi: 10.1158/1541-7786.MCR-14-0278-T. Epub 2014 Sep 30.

19.

Nogo-A-deficient Transgenic Rats Show Deficits in Higher Cognitive Functions, Decreased Anxiety, and Altered Circadian Activity Patterns.

Petrasek T, Prokopova I, Sladek M, Weissova K, Vojtechova I, Bahnik S, Zemanova A, Schönig K, Berger S, Tews B, Bartsch D, Schwab ME, Sumova A, Stuchlik A.

Front Behav Neurosci. 2014 Mar 18;8:90. doi: 10.3389/fnbeh.2014.00090. eCollection 2014.

20.

Reduced expression of nogo-a leads to motivational deficits in rats.

Enkel T, Berger SM, Schönig K, Tews B, Bartsch D.

Front Behav Neurosci. 2014 Jan 22;8:10. doi: 10.3389/fnbeh.2014.00010. eCollection 2014.

21.

Nogo-A downregulation impairs place avoidance in the Carousel maze but not spatial memory in the Morris water maze.

Petrasek T, Prokopova I, Bahnik S, Schonig K, Berger S, Vales K, Tews B, Schwab ME, Bartsch D, Stuchlik A.

Neurobiol Learn Mem. 2014 Jan;107:42-9. doi: 10.1016/j.nlm.2013.10.015. Epub 2013 Nov 6.

PMID:
24211256
22.

N-Methyl-d-Aspartate Receptor - Nitric Oxide Synthase Pathway in the Cortex of Nogo-A-Deficient Rats in Relation to Brain Laterality and Schizophrenia.

Krištofiková Z, Vrajová M, Sírová J, Valeš K, Petrásek T, Schönig K, Tews B, Schwab M, Bartsch D, Stuchlík A, Rípová D.

Front Behav Neurosci. 2013 Aug 12;7:90. doi: 10.3389/fnbeh.2013.00090. eCollection 2013.

23.

Synthetic microRNA-mediated downregulation of Nogo-A in transgenic rats reveals its role as regulator of synaptic plasticity and cognitive function.

Tews B, Schönig K, Arzt ME, Clementi S, Rioult-Pedotti MS, Zemmar A, Berger SM, Schneider M, Enkel T, Weinmann O, Kasper H, Schwab ME, Bartsch D.

Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6583-8. doi: 10.1073/pnas.1217665110. Epub 2013 Apr 1.

24.

Transforming growth factor beta receptor 2 (TGFBR2) changes sialylation in the microsatellite unstable (MSI) Colorectal cancer cell line HCT116.

Lee J, Ballikaya S, Schönig K, Ball CR, Glimm H, Kopitz J, Gebert J.

PLoS One. 2013;8(2):e57074. doi: 10.1371/journal.pone.0057074. Epub 2013 Feb 27.

25.

A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats.

Nuber S, Harmuth F, Kohl Z, Adame A, Trejo M, Schönig K, Zimmermann F, Bauer C, Casadei N, Giel C, Calaminus C, Pichler BJ, Jensen PH, Müller CP, Amato D, Kornhuber J, Teismann P, Yamakado H, Takahashi R, Winkler J, Masliah E, Riess O.

Brain. 2013 Feb;136(Pt 2):412-32. doi: 10.1093/brain/aws358.

26.

Tet-Transgenic Rodents: a comprehensive, up-to date database.

Schönig K, Freundlieb S, Gossen M.

Transgenic Res. 2013 Apr;22(2):251-4. doi: 10.1007/s11248-012-9660-9. Epub 2012 Nov 23.

27.

Conditional gene expression systems in the transgenic rat brain.

Schönig K, Weber T, Frömmig A, Wendler L, Pesold B, Djandji D, Bujard H, Bartsch D.

BMC Biol. 2012 Sep 3;10:77. doi: 10.1186/1741-7007-10-77.

28.

Srgap3⁻/⁻ mice present a neurodevelopmental disorder with schizophrenia-related intermediate phenotypes.

Waltereit R, Leimer U, von Bohlen Und Halbach O, Panke J, Hölter SM, Garrett L, Wittig K, Schneider M, Schmitt C, Calzada-Wack J, Neff F, Becker L, Prehn C, Kutscherjawy S, Endris V, Bacon C, Fuchs H, Gailus-Durner V, Berger S, Schönig K, Adamski J, Klopstock T, Esposito I, Wurst W, de Angelis MH, Rappold G, Wieland T, Bartsch D.

FASEB J. 2012 Nov;26(11):4418-28. doi: 10.1096/fj.11-202317. Epub 2012 Jul 20.

PMID:
22820399
29.

Tetracycline inducible gene manipulation in serotonergic neurons.

Weber T, Renzland I, Baur M, Mönks S, Herrmann E, Huppert V, Nürnberg F, Schönig K, Bartsch D.

PLoS One. 2012;7(5):e38193. doi: 10.1371/journal.pone.0038193. Epub 2012 May 31.

30.

Retrocochlear function of the peripheral deafness gene Cacna1d.

Satheesh SV, Kunert K, Rüttiger L, Zuccotti A, Schönig K, Friauf E, Knipper M, Bartsch D, Nothwang HG.

Hum Mol Genet. 2012 Sep 1;21(17):3896-909. doi: 10.1093/hmg/dds217. Epub 2012 Jun 7.

PMID:
22678062
31.

Inducible gene manipulations in brain serotonergic neurons of transgenic rats.

Weber T, Schönig K, Tews B, Bartsch D.

PLoS One. 2011;6(11):e28283. doi: 10.1371/journal.pone.0028283. Epub 2011 Nov 29.

32.

The power of reversibility regulating gene activities via tetracycline-controlled transcription.

Schönig K, Bujard H, Gossen M.

Methods Enzymol. 2010;477:429-53. doi: 10.1016/S0076-6879(10)77022-1.

PMID:
20699154
33.

Development of a BAC vector for integration-independent and tight regulation of transgenes in rodents via the Tet system.

Schönig K, Kentner D, Gossen M, Baldinger T, Miao J, Welzel K, Vente A, Bartsch D, Bujard H.

Transgenic Res. 2011 Jun;20(3):709-20. doi: 10.1007/s11248-010-9427-0. Epub 2010 Jul 18.

PMID:
20640885
34.

Quantitative analysis of conditional gene inactivation using rationally designed, tetracycline-controlled miRNAs.

Berger SM, Pesold B, Reber S, Schönig K, Berger AJ, Weidenfeld I, Miao J, Berger MR, Gruss OJ, Bartsch D.

Nucleic Acids Res. 2010 Sep;38(17):e168. doi: 10.1093/nar/gkq616. Epub 2010 Jul 17.

35.

Inducible gene manipulations in serotonergic neurons.

Weber T, Böhm G, Hermann E, Schütz G, Schönig K, Bartsch D.

Front Mol Neurosci. 2009 Nov 6;2:24. doi: 10.3389/neuro.02.024.2009. eCollection 2009.

36.

Construction and application of an inducible system for homogenous expression levels in bulk cell lines.

Yu J, Müller H, Hehn S, Koschmieder S, Schönig K, Berdel WE, Serve H, Müller-Tidow C.

PLoS One. 2009 Jul 30;4(7):e6445. doi: 10.1371/journal.pone.0006445.

37.

Highly B lymphocyte-specific tamoxifen inducible transgene expression of CreER T2 by using the LC-1 locus BAC vector.

Boross P, Breukel C, van Loo PF, van der Kaa J, Claassens JW, Bujard H, Schönig K, Verbeek JS.

Genesis. 2009 Nov;47(11):729-35. doi: 10.1002/dvg.20549.

PMID:
19621440
38.

Inducible expression of coding and inhibitory RNAs from retargetable genomic loci.

Weidenfeld I, Gossen M, Löw R, Kentner D, Berger S, Görlich D, Bartsch D, Bujard H, Schönig K.

Nucleic Acids Res. 2009 Apr;37(7):e50. doi: 10.1093/nar/gkp108. Epub 2009 Mar 5.

39.

An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice.

Traykova-Brauch M, Schönig K, Greiner O, Miloud T, Jauch A, Bode M, Felsher DW, Glick AB, Kwiatkowski DJ, Bujard H, Horst J, von Knebel Doeberitz M, Niggli FK, Kriz W, Gröne HJ, Koesters R.

Nat Med. 2008 Sep;14(9):979-84. doi: 10.1038/nm.1865.

40.

The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy.

Mocanu MM, Nissen A, Eckermann K, Khlistunova I, Biernat J, Drexler D, Petrova O, Schönig K, Bujard H, Mandelkow E, Zhou L, Rune G, Mandelkow EM.

J Neurosci. 2008 Jan 16;28(3):737-48. doi: 10.1523/JNEUROSCI.2824-07.2008.

41.

The beta-propensity of Tau determines aggregation and synaptic loss in inducible mouse models of tauopathy.

Eckermann K, Mocanu MM, Khlistunova I, Biernat J, Nissen A, Hofmann A, Schönig K, Bujard H, Haemisch A, Mandelkow E, Zhou L, Rune G, Mandelkow EM.

J Biol Chem. 2007 Oct 26;282(43):31755-65. Epub 2007 Aug 23.

42.

Generation of inducible hepatitis C virus transgenic mouse lines.

Ernst E, Schönig K, Bugert JJ, Bläker H, Pfaff E, Stremmel W, Encke J.

J Med Virol. 2007 Aug;79(8):1103-12.

PMID:
17596832
43.

Tissue-specific expression of ferritin H regulates cellular iron homoeostasis in vivo.

Wilkinson J 4th, Di X, Schönig K, Buss JL, Kock ND, Cline JM, Saunders TL, Bujard H, Torti SV, Torti FM.

Biochem J. 2006 May 1;395(3):501-7.

44.

Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice.

Viatte L, Nicolas G, Lou DQ, Bennoun M, Lesbordes-Brion JC, Canonne-Hergaux F, Schönig K, Bujard H, Kahn A, Andrews NC, Vaulont S.

Blood. 2006 Apr 1;107(7):2952-8. Epub 2005 Dec 8.

45.

Liver-specific expression of interferon gamma following adenoviral gene transfer controls hepatitis B virus replication in mice.

Dumortier J, Schönig K, Oberwinkler H, Löw R, Giese T, Bujard H, Schirmacher P, Protzer U.

Gene Ther. 2005 Apr;12(8):668-77.

PMID:
15647761
46.

A genetic switch for epilepsy in adult mice.

Krestel HE, Shimshek DR, Jensen V, Nevian T, Kim J, Geng Y, Bast T, Depaulis A, Schonig K, Schwenk F, Bujard H, Hvalby Ø, Sprengel R, Seeburg PH.

J Neurosci. 2004 Nov 17;24(46):10568-78.

47.

[Preliminary study on regulable DNA vaccines against Plasmodium falciparum].

Lei JC, Miao J, Li X, Schonig K, Bujard H, Xue CF.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2004 May;20(3):356-9. Chinese.

PMID:
15193238
48.

Use of the tetracycline system for inducible protein synthesis in the kidney.

Gallagher AR, Schönig K, Brown N, Bujard H, Witzgall R.

J Am Soc Nephrol. 2003 Aug;14(8):2042-51.

49.

Conditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis.

Ueberham E, Löw R, Ueberham U, Schönig K, Bujard H, Gebhardt R.

Hepatology. 2003 May;37(5):1067-78.

PMID:
12717387
50.

Stringent doxycycline dependent control of CRE recombinase in vivo.

Schönig K, Schwenk F, Rajewsky K, Bujard H.

Nucleic Acids Res. 2002 Dec 1;30(23):e134.

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