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Best matches for Schön A[au]:

A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Kisalu NK et al. Nat Med. (2018)

A novel lipoate attachment enzyme is shared by Plasmodium and Chlamydia species. Afanador GA et al. Mol Microbiol. (2017)

Three easy pieces. Schön A et al. Biochim Biophys Acta. (2016)

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Items: 1 to 50 of 136

1.

Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.

Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, Cheng C, Dingens AS, Gorman J, Sastry M, Shen CH, Zhang B, Zhou T, Chuang GY, Chao CW, Gu Y, Jafari AJ, Louder MK, O'Dell S, Rowshan AP, Viox EG, Wang Y, Choi CW, Corcoran MM, Corrigan AR, Dandey VP, Eng ET, Geng H, Foulds KE, Guo Y, Kwon YD, Lin B, Liu K, Mason RD, Nason MC, Ohr TY, Ou L, Rawi R, Sarfo EK, Schön A, Todd JP, Wang S, Wei H, Wu W; NISC Comparative Sequencing Program, Mullikin JC, Bailer RT, Doria-Rose NA, Karlsson Hedestam GB, Scorpio DG, Overbaugh J, Bloom JD, Carragher B, Potter CS, Shapiro L, Kwong PD, Mascola JR.

Cell. 2019 Jul 25;178(3):567-584.e19. doi: 10.1016/j.cell.2019.06.030.

2.

Associations between effort-reward imbalance and health indicators among school teachers in Chuquisaca, Bolivia: a cross-sectional study.

Solis-Soto MT, Schön A, Parra M, Radon K.

BMJ Open. 2019 Mar 8;9(3):e025121. doi: 10.1136/bmjopen-2018-025121.

3.

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.

Lai YT, Wang T, O'Dell S, Louder MK, Schön A, Cheung CSF, Chuang GY, Druz A, Lin B, McKee K, Peng D, Yang Y, Zhang B, Herschhorn A, Sodroski J, Bailer RT, Doria-Rose NA, Mascola JR, Langley DR, Kwong PD.

Nat Commun. 2019 Jan 3;10(1):47. doi: 10.1038/s41467-018-07851-1.

4.

Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.

Kisalu NK, Idris AH, Weidle C, Flores-Garcia Y, Flynn BJ, Sack BK, Murphy S, Schön A, Freire E, Francica JR, Miller AB, Gregory J, March S, Liao HX, Haynes BF, Wiehe K, Trama AM, Saunders KO, Gladden MA, Monroe A, Bonsignori M, Kanekiyo M, Wheatley AK, McDermott AB, Farney SK, Chuang GY, Zhang B, Kc N, Chakravarty S, Kwong PD, Sinnis P, Bhatia SN, Kappe SHI, Sim BKL, Hoffman SL, Zavala F, Pancera M, Seder RA.

Nat Med. 2019 Jan;25(1):188-189. doi: 10.1038/s41591-018-0315-0.

PMID:
30552419
5.

SOSIP Changes Affect Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Conformation and CD4 Engagement.

Alsahafi N, Anand SP, Castillo-Menendez L, Verly MM, Medjahed H, Prévost J, Herschhorn A, Richard J, Schön A, Melillo B, Freire E, Smith AB 3rd, Sodroski J, Finzi A.

J Virol. 2018 Sep 12;92(19). pii: e01080-18. doi: 10.1128/JVI.01080-18. Print 2018 Oct 1.

6.

Long term stability of a HIV-1 neutralizing monoclonal antibody using isothermal calorimetry.

Clarkson BR, Chaudhuri R, Schön A, Cooper JW, Kueltzo L, Freire E.

Anal Biochem. 2018 Aug 1;554:61-69. doi: 10.1016/j.ab.2018.05.008. Epub 2018 May 8.

PMID:
29750942
7.

Bioinspired supramolecular engineering of self-assembling immunofibers for high affinity binding of immunoglobulin G.

Li Y, Lock LL, Wang Y, Ou SH, Stern D, Schön A, Freire E, Xu X, Ghose S, Li ZJ, Cui H.

Biomaterials. 2018 Sep;178:448-457. doi: 10.1016/j.biomaterials.2018.04.032. Epub 2018 Apr 16.

PMID:
29706234
8.

[Goldboom's syndrome: prolonged febrile syndrome with dysproteinemia. Case report].

Vázquez MG, Affranchino PN, Schon A, Otero E, Young P, Breyter P.

Arch Argent Pediatr. 2018 Apr 1;116(2):e331-e335. doi: 10.5546/aap.2018.e331. Spanish.

9.

A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.

Kisalu NK, Idris AH, Weidle C, Flores-Garcia Y, Flynn BJ, Sack BK, Murphy S, Schön A, Freire E, Francica JR, Miller AB, Gregory J, March S, Liao HX, Haynes BF, Wiehe K, Trama AM, Saunders KO, Gladden MA, Monroe A, Bonsignori M, Kanekiyo M, Wheatley AK, McDermott AB, Farney SK, Chuang GY, Zhang B, Kc N, Chakravarty S, Kwong PD, Sinnis P, Bhatia SN, Kappe SHI, Sim BKL, Hoffman SL, Zavala F, Pancera M, Seder RA.

Nat Med. 2018 May;24(4):408-416. doi: 10.1038/nm.4512. Epub 2018 Mar 19. Erratum in: Nat Med. 2019 Jan;25(1):188-189.

10.

Publisher Correction: The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions.

Herschhorn A, Gu C, Moraca F, Ma X, Farrell M, Smith AB 3rd, Pancera M, Kwong PD, Schön A, Freire E, Abrams C, Blanchard SC, Mothes W, Sodroski JG.

Nat Commun. 2018 Jan 8;9(1):158. doi: 10.1038/s41467-017-02463-7.

11.

Prevalence of musculoskeletal disorders among school teachers from urban and rural areas in Chuquisaca, Bolivia: a cross-sectional study.

Solis-Soto MT, Schön A, Solis-Soto A, Parra M, Radon K.

BMC Musculoskelet Disord. 2017 Oct 27;18(1):425. doi: 10.1186/s12891-017-1785-9.

12.

The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions.

Herschhorn A, Gu C, Moraca F, Ma X, Farrell M, Smith AB 3rd, Pancera M, Kwong PD, Schön A, Freire E, Abrams C, Blanchard SC, Mothes W, Sodroski JG.

Nat Commun. 2017 Oct 19;8(1):1049. doi: 10.1038/s41467-017-01119-w. Erratum in: Nat Commun. 2018 Jan 8;9(1):158.

13.

A novel lipoate attachment enzyme is shared by Plasmodium and Chlamydia species.

Afanador GA, Guerra AJ, Swift RP, Rodriguez RE, Bartee D, Matthews KA, Schön A, Freire E, Freel Meyers CL, Prigge ST.

Mol Microbiol. 2017 Nov;106(3):439-451. doi: 10.1111/mmi.13776. Epub 2017 Sep 8.

14.

Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.

Pancera M, Lai YT, Bylund T, Druz A, Narpala S, O'Dell S, Schön A, Bailer RT, Chuang GY, Geng H, Louder MK, Rawi R, Soumana DI, Finzi A, Herschhorn A, Madani N, Sodroski J, Freire E, Langley DR, Mascola JR, McDermott AB, Kwong PD.

Nat Chem Biol. 2017 Oct;13(10):1115-1122. doi: 10.1038/nchembio.2460. Epub 2017 Aug 21.

15.

Temperature stability of proteins: Analysis of irreversible denaturation using isothermal calorimetry.

Schön A, Clarkson BR, Jaime M, Freire E.

Proteins. 2017 Nov;85(11):2009-2016. doi: 10.1002/prot.25354. Epub 2017 Aug 8.

16.

Enthalpy screen of drug candidates.

Schön A, Freire E.

Anal Biochem. 2016 Nov 15;513:1-6. doi: 10.1016/j.ab.2016.08.023. Epub 2016 Aug 25.

17.

Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition.

Melillo B, Liang S, Park J, Schön A, Courter JR, LaLonde JM, Wendler DJ, Princiotto AM, Seaman MS, Freire E, Sodroski J, Madani N, Hendrickson WA, Smith AB 3rd.

ACS Med Chem Lett. 2016 Jan 19;7(3):330-4. doi: 10.1021/acsmedchemlett.5b00471. eCollection 2016 Mar 10.

18.

Fibroblast growth factor 23 signaling in hippocampal cells: impact on neuronal morphology and synaptic density.

Hensel N, Schön A, Konen T, Lübben V, Förthmann B, Baron O, Grothe C, Leifheit-Nestler M, Claus P, Haffner D.

J Neurochem. 2016 Jun;137(5):756-69. doi: 10.1111/jnc.13585. Epub 2016 Mar 7.

19.

Three easy pieces.

Schön A, Freire E.

Biochim Biophys Acta. 2016 May;1860(5):975-980. doi: 10.1016/j.bbagen.2015.12.003. Epub 2015 Dec 9.

20.

Conformational stability and self-association equilibrium in biologics.

Clarkson BR, Schön A, Freire E.

Drug Discov Today. 2016 Feb;21(2):342-7. doi: 10.1016/j.drudis.2015.11.007. Epub 2015 Nov 19. Review.

21.

Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo.

Xu Q, Ensign LM, Boylan NJ, Schön A, Gong X, Yang JC, Lamb NW, Cai S, Yu T, Freire E, Hanes J.

ACS Nano. 2015 Sep 22;9(9):9217-27. doi: 10.1021/acsnano.5b03876. Epub 2015 Aug 31.

22.

Denatured state aggregation parameters derived from concentration dependence of protein stability.

Schön A, Clarkson BR, Siles R, Ross P, Brown RK, Freire E.

Anal Biochem. 2015 Nov 1;488:45-50. doi: 10.1016/j.ab.2015.07.013. Epub 2015 Aug 1.

PMID:
26239214
23.

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env.

Kwon YD, Pancera M, Acharya P, Georgiev IS, Crooks ET, Gorman J, Joyce MG, Guttman M, Ma X, Narpala S, Soto C, Terry DS, Yang Y, Zhou T, Ahlsen G, Bailer RT, Chambers M, Chuang GY, Doria-Rose NA, Druz A, Hallen MA, Harned A, Kirys T, Louder MK, O'Dell S, Ofek G, Osawa K, Prabhakaran M, Sastry M, Stewart-Jones GB, Stuckey J, Thomas PV, Tittley T, Williams C, Zhang B, Zhao H, Zhou Z, Donald BR, Lee LK, Zolla-Pazner S, Baxa U, Schön A, Freire E, Shapiro L, Lee KK, Arthos J, Munro JB, Blanchard SC, Mothes W, Binley JM, McDermott AB, Mascola JR, Kwong PD.

Nat Struct Mol Biol. 2015 Jul;22(7):522-31. doi: 10.1038/nsmb.3051. Epub 2015 Jun 22.

24.

[The Convention on the Rights of the Child in Action: the Hospital Garrahan's experience through mainstreaming the rights approach into health care].

Schön A, Hammermüller E, Di Tommaso V, Bagari G.

Arch Argent Pediatr. 2015 Jun;113(3):269-75. doi: 10.5546/aap.2015.269. Spanish.

25.

CD4 mimetics sensitize HIV-1-infected cells to ADCC.

Richard J, Veillette M, Brassard N, Iyer SS, Roger M, Martin L, Pazgier M, Schön A, Freire E, Routy JP, Smith AB 3rd, Park J, Jones DM, Courter JR, Melillo BN, Kaufmann DE, Hahn BH, Permar SR, Haynes BF, Madani N, Sodroski JG, Finzi A.

Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2687-94. doi: 10.1073/pnas.1506755112. Epub 2015 May 4.

26.

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.

Georgiev IS, Joyce MG, Yang Y, Sastry M, Zhang B, Baxa U, Chen RE, Druz A, Lees CR, Narpala S, Schön A, Van Galen J, Chuang GY, Gorman J, Harned A, Pancera M, Stewart-Jones GB, Cheng C, Freire E, McDermott AB, Mascola JR, Kwong PD.

J Virol. 2015 May;89(10):5318-29. doi: 10.1128/JVI.03451-14. Epub 2015 Mar 4.

27.

CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies.

Madani N, Princiotto AM, Schön A, LaLonde J, Feng Y, Freire E, Park J, Courter JR, Jones DM, Robinson J, Liao HX, Moody MA, Permar S, Haynes B, Smith AB 3rd, Wyatt R, Sodroski J.

J Virol. 2014 Jun;88(12):6542-55. doi: 10.1128/JVI.00540-14. Epub 2014 Apr 2.

28.

Structure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist.

Courter JR, Madani N, Sodroski J, Schön A, Freire E, Kwong PD, Hendrickson WA, Chaiken IM, LaLonde JM, Smith AB 3rd.

Acc Chem Res. 2014 Apr 15;47(4):1228-37. doi: 10.1021/ar4002735. Epub 2014 Feb 6. Review.

29.

HIV-1 Vif N-terminal motif is required for recruitment of Cul5 to suppress APOBEC3.

Evans SL, Schön A, Gao Q, Han X, Zhou X, Freire E, Yu XF.

Retrovirology. 2014 Jan 14;11:4. doi: 10.1186/1742-4690-11-4.

30.

Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay.

Afanador GA, Muench SP, McPhillie M, Fomovska A, Schön A, Zhou Y, Cheng G, Stec J, Freundlich JS, Shieh HM, Anderson JW, Jacobus DP, Fidock DA, Kozikowski AP, Fishwick CW, Rice DW, Freire E, McLeod R, Prigge ST.

Biochemistry. 2013 Dec 23;52(51):9155-66. doi: 10.1021/bi400945y. Epub 2013 Dec 13.

31.

Nudel/NudE and Lis1 promote dynein and dynactin interaction in the context of spindle morphogenesis.

Wang S, Ketcham SA, Schön A, Goodman B, Wang Y, Yates J 3rd, Freire E, Schroer TA, Zheng Y.

Mol Biol Cell. 2013 Nov;24(22):3522-33. doi: 10.1091/mbc.E13-05-0283. Epub 2013 Sep 11.

32.

Ligand binding analysis and screening by chemical denaturation shift.

Schön A, Brown RK, Hutchins BM, Freire E.

Anal Biochem. 2013 Dec 1;443(1):52-7. doi: 10.1016/j.ab.2013.08.015. Epub 2013 Aug 29.

33.

Development of potent dipeptide-type SARS-CoV 3CL protease inhibitors with novel P3 scaffolds: design, synthesis, biological evaluation, and docking studies.

Thanigaimalai P, Konno S, Yamamoto T, Koiwai Y, Taguchi A, Takayama K, Yakushiji F, Akaji K, Chen SE, Naser-Tavakolian A, Schön A, Freire E, Hayashi Y.

Eur J Med Chem. 2013 Oct;68:372-84. doi: 10.1016/j.ejmech.2013.07.037. Epub 2013 Aug 9.

PMID:
23994330
34.

Chemical denaturation as a tool in the formulation optimization of biologics.

Freire E, Schön A, Hutchins BM, Brown RK.

Drug Discov Today. 2013 Oct;18(19-20):1007-13. doi: 10.1016/j.drudis.2013.06.005. Epub 2013 Jun 21. Review.

35.

Design, synthesis, and biological evaluation of novel dipeptide-type SARS-CoV 3CL protease inhibitors: structure-activity relationship study.

Thanigaimalai P, Konno S, Yamamoto T, Koiwai Y, Taguchi A, Takayama K, Yakushiji F, Akaji K, Kiso Y, Kawasaki Y, Chen SE, Naser-Tavakolian A, Schön A, Freire E, Hayashi Y.

Eur J Med Chem. 2013 Jul;65:436-47. doi: 10.1016/j.ejmech.2013.05.005. Epub 2013 May 20.

PMID:
23747811
36.

Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization.

Lalonde JM, Le-Khac M, Jones DM, Courter JR, Park J, Schön A, Princiotto AM, Wu X, Mascola JR, Freire E, Sodroski J, Madani N, Hendrickson WA, Smith AB 3rd.

ACS Med Chem Lett. 2013 Mar 14;4(3):338-343.

37.

Non-natural peptide triazole antagonists of HIV-1 envelope gp120.

Kamanna K, Aneja R, Duffy C, Kubinski P, Rodrigo Moreira D, Bailey LD, McFadden K, Schön A, Holmes A, Tuzer F, Contarino M, Freire E, Chaiken IM.

ChemMedChem. 2013 Feb;8(2):322-8. doi: 10.1002/cmdc.201200422. Epub 2012 Dec 13.

38.

Optimization of CD4/gp120 inhibitors by thermodynamic-guided alanine-scanning mutagenesis.

Liu Y, Schön A, Freire E.

Chem Biol Drug Des. 2013 Jan;81(1):72-8. doi: 10.1111/cbdd.12075.

39.

Photochemical control of RNA structure by disrupting π-stacking.

Resendiz MJ, Schön A, Freire E, Greenberg MM.

J Am Chem Soc. 2012 Aug 1;134(30):12478-81. doi: 10.1021/ja306304w. Epub 2012 Jul 24.

40.

Inhibiting early-stage events in HIV-1 replication by small-molecule targeting of the HIV-1 capsid.

Kortagere S, Madani N, Mankowski MK, Schön A, Zentner I, Swaminathan G, Princiotto A, Anthony K, Oza A, Sierra LJ, Passic SR, Wang X, Jones DM, Stavale E, Krebs FC, Martín-García J, Freire E, Ptak RG, Sodroski J, Cocklin S, Smith AB 3rd.

J Virol. 2012 Aug;86(16):8472-81. doi: 10.1128/JVI.05006-11. Epub 2012 May 30.

41.

RNase MRP RNA and RNase P activity in plants are associated with a Pop1p containing complex.

Krehan M, Heubeck C, Menzel N, Seibel P, Schön A.

Nucleic Acids Res. 2012 Sep;40(16):7956-66. doi: 10.1093/nar/gks476. Epub 2012 May 27.

42.

Structure-based design, synthesis, and characterization of dual hotspot small-molecule HIV-1 entry inhibitors.

LaLonde JM, Kwon YD, Jones DM, Sun AW, Courter JR, Soeta T, Kobayashi T, Princiotto AM, Wu X, Schön A, Freire E, Kwong PD, Mascola JR, Sodroski J, Madani N, Smith AB 3rd.

J Med Chem. 2012 May 10;55(9):4382-96. doi: 10.1021/jm300265j. Epub 2012 Apr 23.

43.

JAM-C is an apical surface marker for neural stem cells.

Stelzer S, Worlitzer MM, Bahnassawy L, Hemmer K, Rugani K, Werthschulte I, Schön AL, Brinkmann BF, Bunk EC, Palm T, Ebnet K, Schwamborn JC.

Stem Cells Dev. 2012 Mar 20;21(5):757-66. doi: 10.1089/scd.2011.0274. Epub 2012 Jan 17.

PMID:
22114908
44.

Thermodynamics-based drug design: strategies for inhibiting protein-protein interactions.

Schön A, Lam SY, Freire E.

Future Med Chem. 2011 Jul;3(9):1129-37. doi: 10.4155/fmc.11.81. Review.

45.

Transarterial hepatic yttrium-90 radioembolization in patients with unresectable intrahepatic cholangiocarcinoma: factors associated with prolonged survival.

Hoffmann RT, Paprottka PM, Schön A, Bamberg F, Haug A, Dürr EM, Rauch B, Trumm CT, Jakobs TF, Helmberger TK, Reiser MF, Kolligs FT.

Cardiovasc Intervent Radiol. 2012 Feb;35(1):105-16. doi: 10.1007/s00270-011-0142-x. Epub 2011 Mar 24.

PMID:
21431970
46.

Conformational and structural features of HIV-1 gp120 underlying the dual receptor antagonism by cross-reactive neutralizing antibody m18.

Gift SK, Zentner IJ, Schön A, McFadden K, Umashankara M, Rajagopal S, Contarino M, Duffy C, Courter JR, Zhang MY, Gershoni JM, Cocklin S, Dimitrov DS, Smith AB 3rd, Freire E, Chaiken IM.

Biochemistry. 2011 Apr 12;50(14):2756-68. doi: 10.1021/bi101160r. Epub 2011 Mar 18.

47.

Some binding-related drug properties are dependent on thermodynamic signature.

Schön A, Madani N, Smith AB, Lalonde JM, Freire E.

Chem Biol Drug Des. 2011 Mar;77(3):161-5. doi: 10.1111/j.1747-0285.2010.01075.x. Epub 2011 Feb 2.

48.

Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening.

Lalonde JM, Elban MA, Courter JR, Sugawara A, Soeta T, Madani N, Princiotto AM, Kwon YD, Kwong PD, Schön A, Freire E, Sodroski J, Smith AB 3rd.

Bioorg Med Chem. 2011 Jan 1;19(1):91-101. doi: 10.1016/j.bmc.2010.11.049. Epub 2010 Nov 26.

49.

The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.

Umashankara M, McFadden K, Zentner I, Schön A, Rajagopal S, Tuzer F, Kuriakose SA, Contarino M, Lalonde J, Freire E, Chaiken I.

ChemMedChem. 2010 Nov 8;5(11):1871-9. doi: 10.1002/cmdc.201000222.

50.

Naturally occurring variability in the envelope glycoprotein of HIV-1 and development of cell entry inhibitors.

Brower ET, Schön A, Freire E.

Biochemistry. 2010 Mar 23;49(11):2359-67. doi: 10.1021/bi1000933.

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