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Best matches for Schäfer MK[au]:

NG2/CSPG4 and progranulin in the posttraumatic glial scar. Schäfer MKE et al. Matrix Biol. (2018)

Perivascular microglia promote blood vessel disintegration in the ischemic penumbra. Jolivel V et al. Acta Neuropathol. (2015)

Preclinical evaluation of PAC1 targeting with radiolabeled Maxadilan. Joosten L et al. Sci Rep. (2017)

Search results

Items: 1 to 50 of 174

1.

Depletion of regulatory T cells increases T cell brain infiltration, reactive astrogliosis, and interferon-γ gene expression in acute experimental traumatic brain injury.

Krämer TJ, Hack N, Brühl TJ, Menzel L, Hummel R, Griemert EV, Klein M, Thal SC, Bopp T, Schäfer MKE.

J Neuroinflammation. 2019 Aug 5;16(1):163. doi: 10.1186/s12974-019-1550-0.

2.

Angiotensin II Receptor 1 Blockage Limits Brain Damage and Improves Functional Outcome After Brain Injury in Aged Animals Despite Age-Dependent Reduction in AT1 Expression.

Timaru-Kast R, Gotthardt P, Luh C, Huang C, Hummel R, Schäfer MKE, Thal SC.

Front Aging Neurosci. 2019 Apr 26;11:63. doi: 10.3389/fnagi.2019.00063. eCollection 2019.

3.

Neural cell adhesion molecule Negr1 deficiency in mouse results in structural brain endophenotypes and behavioral deviations related to psychiatric disorders.

Singh K, Jayaram M, Kaare M, Leidmaa E, Jagomäe T, Heinla I, Hickey MA, Kaasik A, Schäfer MK, Innos J, Lilleväli K, Philips MA, Vasar E.

Sci Rep. 2019 Apr 1;9(1):5457. doi: 10.1038/s41598-019-41991-8.

4.

Plasminogen activator inhibitor-1 augments damage by impairing fibrinolysis after traumatic brain injury.

Griemert EV, Schwarzmaier SM, Hummel R, Gölz C, Yang D, Neuhaus W, Burek M, Förster CY, Petkovic I, Trabold R, Plesnila N, Engelhard K, Schäfer MK, Thal SC.

Ann Neurol. 2019 May;85(5):667-680. doi: 10.1002/ana.25458. Epub 2019 Mar 30.

5.

Sex hormones modulate pathogenic processes in experimental traumatic brain injury.

Gölz C, Kirchhoff FP, Westerhorstmann J, Schmidt M, Hirnet T, Rune GM, Bender RA, Schäfer MKE.

J Neurochem. 2019 Jul;150(2):173-187. doi: 10.1111/jnc.14678. Epub 2019 Feb 20.

PMID:
30790293
6.

NEGR1 and FGFR2 cooperatively regulate cortical development and core behaviours related to autism disorders in mice.

Szczurkowska J, Pischedda F, Pinto B, Managò F, Haas CA, Summa M, Bertorelli R, Papaleo F, Schäfer MK, Piccoli G, Cancedda L.

Brain. 2018 Sep 1;141(9):2772-2794. doi: 10.1093/brain/awy190.

7.

PAI-1 but Not PAI-2 Gene Deficiency Attenuates Ischemic Brain Injury After Experimental Stroke.

Griemert EV, Recarte Pelz K, Engelhard K, Schäfer MK, Thal SC.

Transl Stroke Res. 2019 Aug;10(4):372-380. doi: 10.1007/s12975-018-0644-9. Epub 2018 Jul 5.

8.

The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function.

Silbernagel N, Walecki M, Schäfer MK, Kessler M, Zobeiri M, Rinné S, Kiper AK, Komadowski MA, Vowinkel KS, Wemhöner K, Fortmüller L, Schewe M, Dolga AM, Scekic-Zahirovic J, Matschke LA, Culmsee C, Baukrowitz T, Monassier L, Ullrich ND, Dupuis L, Just S, Budde T, Fabritz L, Decher N.

FASEB J. 2018 Nov;32(11):6159-6173. doi: 10.1096/fj.201800246R. Epub 2018 Jun 7.

9.

Adult rat myelin enhances axonal outgrowth from neural stem cells.

Poplawski GHD, Lie R, Hunt M, Kumamaru H, Kawaguchi R, Lu P, Schäfer MKE, Woodruff G, Robinson J, Canete P, Dulin JN, Geoffroy CG, Menzel L, Zheng B, Coppola G, Tuszynski MH.

Sci Transl Med. 2018 May 23;10(442). pii: eaal2563. doi: 10.1126/scitranslmed.aal2563.

PMID:
29794059
10.

Neuronal Growth and Behavioral Alterations in Mice Deficient for the Psychiatric Disease-Associated Negr1 Gene.

Singh K, Loreth D, Pöttker B, Hefti K, Innos J, Schwald K, Hengstler H, Menzel L, Sommer CJ, Radyushkin K, Kretz O, Philips MA, Haas CA, Frauenknecht K, Lilleväli K, Heimrich B, Vasar E, Schäfer MKE.

Front Mol Neurosci. 2018 Feb 9;11:30. doi: 10.3389/fnmol.2018.00030. eCollection 2018.

11.

NG2/CSPG4 and progranulin in the posttraumatic glial scar.

Schäfer MKE, Tegeder I.

Matrix Biol. 2018 Aug;68-69:571-588. doi: 10.1016/j.matbio.2017.10.002. Epub 2017 Oct 17. Review.

PMID:
29054751
12.

Loss of synaptic zinc transport in progranulin deficient mice may contribute to progranulin-associated psychopathology and chronic pain.

Hardt S, Heidler J, Albuquerque B, Valek L, Altmann C, Wilken-Schmitz A, Schäfer MKE, Wittig I, Tegeder I.

Biochim Biophys Acta Mol Basis Dis. 2017 Nov;1863(11):2727-2745. doi: 10.1016/j.bbadis.2017.07.014. Epub 2017 Jul 15.

13.

Traumatic brain injury causes long-term behavioral changes related to region-specific increases of cerebral blood flow.

Pöttker B, Stöber F, Hummel R, Angenstein F, Radyushkin K, Goldschmidt J, Schäfer MKE.

Brain Struct Funct. 2017 Dec;222(9):4005-4021. doi: 10.1007/s00429-017-1452-9. Epub 2017 Jun 6.

PMID:
28589257
14.

Preclinical evaluation of PAC1 targeting with radiolabeled Maxadilan.

Joosten L, Brom M, Schäfer MKH, Boerman OC, Weihe E, Gotthardt M.

Sci Rep. 2017 May 11;7(1):1751. doi: 10.1038/s41598-017-01852-8.

15.

Osteointegration and Resorption of Intravertebral and Extravertebral Calcium Phosphate Cement.

Klein R, Tetzlaff R, Weiss C, Schäfer MK, Tanner M, Wiedenhöfer B, Grafe I, Meeder PJ, Noeldge G, Nawroth PP, Kasperk C.

Clin Spine Surg. 2017 Apr;30(3):E291-E296. doi: 10.1097/BSD.0b013e3182aab2df.

PMID:
28323714
16.

Sex-Dependent Regulation of Aromatase-Mediated Synaptic Plasticity in the Basolateral Amygdala.

Bender RA, Zhou L, Vierk R, Brandt N, Keller A, Gee CE, Schäfer MK, Rune GM.

J Neurosci. 2017 Feb 8;37(6):1532-1545. doi: 10.1523/JNEUROSCI.1532-16.2016. Epub 2016 Dec 27.

17.

Progranulin protects against exaggerated axonal injury and astrogliosis following traumatic brain injury.

Menzel L, Kleber L, Friedrich C, Hummel R, Dangel L, Winter J, Schmitz K, Tegeder I, Schäfer MK.

Glia. 2017 Feb;65(2):278-292. doi: 10.1002/glia.23091. Epub 2016 Oct 25.

PMID:
27778404
18.

Down-regulation of neuronal L1 cell adhesion molecule expression alleviates inflammatory neuronal injury.

Menzel L, Paterka M, Bittner S, White R, Bobkiewicz W, van Horssen J, Schachner M, Witsch E, Kuhlmann T, Zipp F, Schäfer MK.

Acta Neuropathol. 2016 Nov;132(5):703-720. Epub 2016 Aug 20.

PMID:
27544757
19.

Sensory neuropathy in progressive motor neuronopathy (pmn) mice is associated with defects in microtubule polymerization and axonal transport.

Schäfer MK, Bellouze S, Jacquier A, Schaller S, Richard L, Mathis S, Vallat JM, Haase G.

Brain Pathol. 2017 Jul;27(4):459-471. doi: 10.1111/bpa.12422. Epub 2016 Oct 18.

PMID:
27488538
20.

Plasticity Related Gene 3 (PRG3) overcomes myelin-associated growth inhibition and promotes functional recovery after spinal cord injury.

Broggini T, Schnell L, Ghoochani A, Mateos JM, Buchfelder M, Wiendieck K, Schäfer MK, Eyupoglu IY, Savaskan NE.

Aging (Albany NY). 2016 Oct 15;8(10):2463-2487. doi: 10.18632/aging.101066.

21.

l-DOPA-induced dyskinesia is associated with a deficient numerical downregulation of striatal tyrosine hydroxylase mRNA-expressing neurons.

Klietz M, Keber U, Carlsson T, Chiu WH, Höglinger GU, Weihe E, Schäfer MK, Depboylu C.

Neuroscience. 2016 Sep 7;331:120-33. doi: 10.1016/j.neuroscience.2016.06.017. Epub 2016 Jun 16.

PMID:
27320210
22.

L1 syndrome diagnosis complemented with functional analysis of L1CAM variants located to the two N-terminal Ig-like domains.

Christaller WA, Vos Y, Gebre-Medhin S, Hofstra RM, Schäfer MK.

Clin Genet. 2017 Jan;91(1):115-120. doi: 10.1111/cge.12763. Epub 2016 Mar 15.

PMID:
26891472
23.

Lack of NG2 exacerbates neurological outcome and modulates glial responses after traumatic brain injury.

Huang C, Sakry D, Menzel L, Dangel L, Sebastiani A, Krämer T, Karram K, Engelhard K, Trotter J, Schäfer MK.

Glia. 2016 Apr;64(4):507-23. doi: 10.1002/glia.22944. Epub 2015 Dec 6.

PMID:
26638112
24.

Posttraumatic Propofol Neurotoxicity Is Mediated via the Pro-Brain-Derived Neurotrophic Factor-p75 Neurotrophin Receptor Pathway in Adult Mice.

Sebastiani A, Granold M, Ditter A, Sebastiani P, Gölz C, Pöttker B, Luh C, Schaible EV, Radyushkin K, Timaru-Kast R, Werner C, Schäfer MK, Engelhard K, Moosmann B, Thal SC.

Crit Care Med. 2016 Feb;44(2):e70-82. doi: 10.1097/CCM.0000000000001284.

PMID:
26317567
25.

Striatal tyrosine hydroxylase-positive neurons are associated with L-DOPA-induced dyskinesia in hemiparkinsonian mice.

Keber U, Klietz M, Carlsson T, Oertel WH, Weihe E, Schäfer MK, Höglinger GU, Depboylu C.

Neuroscience. 2015 Jul 9;298:302-17. doi: 10.1016/j.neuroscience.2015.04.021. Epub 2015 Apr 16.

PMID:
25892702
26.

Proneurotrophin Binding to P75 Neurotrophin Receptor (P75ntr) Is Essential for Brain Lesion Formation and Functional Impairment after Experimental Traumatic Brain Injury.

Sebastiani A, Gölz C, Werner C, Schäfer MK, Engelhard K, Thal SC.

J Neurotrauma. 2015 Oct 15;32(20):1599-607. doi: 10.1089/neu.2014.3751. Epub 2015 Jun 30.

PMID:
25879397
27.

Early subcellular Ca2+ remodelling and increased propensity for Ca2+ alternans in left atrial myocytes from hypertensive rats.

Pluteanu F, Heß J, Plackic J, Nikonova Y, Preisenberger J, Bukowska A, Schotten U, Rinne A, Kienitz MC, Schäfer MK, Weihe E, Goette A, Kockskämper J.

Cardiovasc Res. 2015 Apr 1;106(1):87-97. doi: 10.1093/cvr/cvv045. Epub 2015 Feb 17.

PMID:
25691541
28.

Perivascular microglia promote blood vessel disintegration in the ischemic penumbra.

Jolivel V, Bicker F, Binamé F, Ploen R, Keller S, Gollan R, Jurek B, Birkenstock J, Poisa-Beiro L, Bruttger J, Opitz V, Thal SC, Waisman A, Bäuerle T, Schäfer MK, Zipp F, Schmidt MHH.

Acta Neuropathol. 2015 Feb;129(2):279-95. doi: 10.1007/s00401-014-1372-1. Epub 2014 Dec 13.

PMID:
25500713
29.

Transcriptional and structural plasticity of tyrosine hydroxylase expressing neurons in both striatum and nucleus accumbens following dopaminergic denervation.

Depboylu C, Klietz M, Maurer L, Oertel WH, Kobayashi K, Weihe E, Höglinger GU, Schäfer MK.

J Chem Neuroanat. 2014 Nov;61-62:169-75. doi: 10.1016/j.jchemneu.2014.10.003. Epub 2014 Oct 29.

PMID:
25451178
30.

Satb2-independent acquisition of the cholinergic sudomotor phenotype in rodents.

Schütz B, Schäfer MK, Gördes M, Eiden LE, Weihe E.

Cell Mol Neurobiol. 2015 Mar;35(2):205-16. doi: 10.1007/s10571-014-0113-2. Epub 2014 Sep 20.

31.

Golgi fragmentation in pmn mice is due to a defective ARF1/TBCE cross-talk that coordinates COPI vesicle formation and tubulin polymerization.

Bellouze S, Schäfer MK, Buttigieg D, Baillat G, Rabouille C, Haase G.

Hum Mol Genet. 2014 Nov 15;23(22):5961-75. doi: 10.1093/hmg/ddu320. Epub 2014 Jun 20.

PMID:
24951541
32.

Regulators of mitochondrial Ca(2+) homeostasis in cerebral ischemia.

Schäfer MK, Pfeiffer A, Jaeckel M, Pouya A, Dolga AM, Methner A.

Cell Tissue Res. 2014 Aug;357(2):395-405. doi: 10.1007/s00441-014-1807-y. Epub 2014 Apr 9. Review.

PMID:
24715113
33.

2-Methoxyestradiol confers neuroprotection and inhibits a maladaptive HIF-1α response after traumatic brain injury in mice.

Schaible EV, Windschügl J, Bobkiewicz W, Kaburov Y, Dangel L, Krämer T, Huang C, Sebastiani A, Luh C, Werner C, Engelhard K, Thal SC, Schäfer MK.

J Neurochem. 2014 Jun;129(6):940-54. doi: 10.1111/jnc.12708. Epub 2014 Apr 2.

34.

The sympathetic nervous system modulates CD4(+)Foxp3(+) regulatory T cells via noradrenaline-dependent apoptosis in a murine model of lymphoproliferative disease.

Wirth T, Westendorf AM, Bloemker D, Wildmann J, Engler H, Mollerus S, Wadwa M, Schäfer MK, Schedlowski M, del Rey A.

Brain Behav Immun. 2014 May;38:100-10. doi: 10.1016/j.bbi.2014.01.007. Epub 2014 Jan 15.

PMID:
24440144
35.

Mitochondrial function and energy metabolism in neuronal HT22 cells resistant to oxidative stress.

Pfeiffer A, Jaeckel M, Lewerenz J, Noack R, Pouya A, Schacht T, Hoffmann C, Winter J, Schweiger S, Schäfer MK, Methner A.

Br J Pharmacol. 2014 Apr;171(8):2147-58. doi: 10.1111/bph.12549.

36.

Localization and expression of VMAT2 aross mammalian species: a translational guide for its visualization and targeting in health and disease.

Schafer MK, Weihe E, Eiden LE.

Adv Pharmacol. 2013;68:319-34. doi: 10.1016/B978-0-12-411512-5.00015-4. Review.

37.

Single administration of tripeptide α-MSH(11-13) attenuates brain damage by reduced inflammation and apoptosis after experimental traumatic brain injury in mice.

Schaible EV, Steinsträßer A, Jahn-Eimermacher A, Luh C, Sebastiani A, Kornes F, Pieter D, Schäfer MK, Engelhard K, Thal SC.

PLoS One. 2013 Aug 5;8(8):e71056. doi: 10.1371/journal.pone.0071056. Print 2013.

38.

PACAP signaling exerts opposing effects on neuroprotection and neuroinflammation during disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

Ringer C, Büning LS, Schäfer MK, Eiden LE, Weihe E, Schütz B.

Neurobiol Dis. 2013 Jun;54:32-42. doi: 10.1016/j.nbd.2013.02.010. Epub 2013 Mar 4.

39.

Species-specific vesicular monoamine transporter 2 (VMAT2) expression in mammalian pancreatic beta cells: implications for optimising radioligand-based human beta cell mass (BCM) imaging in animal models.

Schäfer MK, Hartwig NR, Kalmbach N, Klietz M, Anlauf M, Eiden LE, Weihe E.

Diabetologia. 2013 May;56(5):1047-56. doi: 10.1007/s00125-013-2847-7. Epub 2013 Feb 13.

40.

EGFL7 ligates αvβ3 integrin to enhance vessel formation.

Nikolic I, Stankovic ND, Bicker F, Meister J, Braun H, Awwad K, Baumgart J, Simon K, Thal SC, Patra C, Harter PN, Plate KH, Engel FB, Dimmeler S, Eble JA, Mittelbronn M, Schäfer MK, Jungblut B, Chavakis E, Fleming I, Schmidt MHH.

Blood. 2013 Apr 11;121(15):3041-50. doi: 10.1182/blood-2011-11-394882. Epub 2013 Feb 5.

41.

Influence of age on brain edema formation, secondary brain damage and inflammatory response after brain trauma in mice.

Timaru-Kast R, Luh C, Gotthardt P, Huang C, Schäfer MK, Engelhard K, Thal SC.

PLoS One. 2012;7(8):e43829. doi: 10.1371/journal.pone.0043829. Epub 2012 Aug 30.

42.

Functional inactivation of the genome-wide association study obesity gene neuronal growth regulator 1 in mice causes a body mass phenotype.

Lee AW, Hengstler H, Schwald K, Berriel-Diaz M, Loreth D, Kirsch M, Kretz O, Haas CA, de Angelis MH, Herzig S, Brümmendorf T, Klingenspor M, Rathjen FG, Rozman J, Nicholson G, Cox RD, Schäfer MK.

PLoS One. 2012;7(7):e41537. doi: 10.1371/journal.pone.0041537. Epub 2012 Jul 23.

43.

Role of L1CAM for axon sprouting and branching.

Schäfer MK, Frotscher M.

Cell Tissue Res. 2012 Jul;349(1):39-48. doi: 10.1007/s00441-012-1345-4. Epub 2012 Feb 28. Review.

PMID:
22370595
44.

Pathomechanistic characterization of two exonic L1CAM variants located in trans in an obligate carrier of X-linked hydrocephalus.

Marx M, Diestel S, Bozon M, Keglowich L, Drouot N, Bouché E, Frebourg T, Minz M, Saugier-Veber P, Castellani V, Schäfer MK.

Neurogenetics. 2012 Feb;13(1):49-59. doi: 10.1007/s10048-011-0307-4. Epub 2012 Jan 6.

PMID:
22222883
45.

Gene expression of enzymes required for the de novo synthesis and degradation of pyrimidines in rat peripheral tissues and brain.

Gerlach J, Löffler M, Schäfer MK.

Nucleosides Nucleotides Nucleic Acids. 2011 Dec;30(12):1147-54. doi: 10.1080/15257770.2011.603712.

PMID:
22132969
46.

Upregulation of microglial C1q expression has no effects on nigrostriatal dopaminergic injury in the MPTP mouse model of Parkinson disease.

Depboylu C, Schorlemmer K, Klietz M, Oertel WH, Weihe E, Höglinger GU, Schäfer MK.

J Neuroimmunol. 2011 Jul;236(1-2):39-46. doi: 10.1016/j.jneuroim.2011.05.006.

PMID:
21640391
47.

Full-length L1CAM and not its Δ2Δ27 splice variant promotes metastasis through induction of gelatinase expression.

Hauser S, Bickel L, Weinspach D, Gerg M, Schäfer MK, Pfeifer M, Hazin J, Schelter F, Weidle UH, Ramser J, Volkmann J, Meindl A, Schmitt M, Schrötzlmair F, Altevogt P, Krüger A.

PLoS One. 2011 Apr 25;6(4):e18989. doi: 10.1371/journal.pone.0018989.

48.

Possible involvement of complement factor C1q in the clearance of extracellular neuromelanin from the substantia nigra in Parkinson disease.

Depboylu C, Schäfer MK, Arias-Carrión O, Oertel WH, Weihe E, Höglinger GU.

J Neuropathol Exp Neurol. 2011 Feb;70(2):125-32. doi: 10.1097/NEN.0b013e31820805b9.

PMID:
21343881
49.

Epileptiform activity interferes with proteolytic processing of Reelin required for dentate granule cell positioning.

Tinnes S, Schäfer MK, Flubacher A, Münzner G, Frotscher M, Haas CA.

FASEB J. 2011 Mar;25(3):1002-13. doi: 10.1096/fj.10-168294. Epub 2010 Dec 8.

PMID:
21148112
50.

L1CAM ubiquitination facilitates its lysosomal degradation.

Schäfer MK, Schmitz B, Diestel S.

FEBS Lett. 2010 Nov 5;584(21):4475-80. doi: 10.1016/j.febslet.2010.10.011. Epub 2010 Oct 14.

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