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PAX3-FOXO1: Zooming in on an "undruggable" target. Wachtel M et al. Semin Cancer Biol. (2018)

Safety Aspects of the Use of Quercetin as a Dietary Supplement. Andres S et al. Mol Nutr Food Res. (2018)

The MLL recombinome of acute leukemias in 2017. Meyer C et al. Leukemia. (2018)

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Items: 1 to 50 of 427


Dietary Manganese Exposure in the Adult Population in Germany-What Does it Mean in Relation to Health Risks?

Sachse B, Kolbaum AE, Ziegenhagen R, Andres S, Berg K, Dusemund B, Hirsch-Ernst KI, Kappenstein O, Müller F, Röhl C, Lindtner O, Lampen A, Schäfer B.

Mol Nutr Food Res. 2019 Jun 19:e1900065. doi: 10.1002/mnfr.201900065. [Epub ahead of print] Review.


Standardisation and consensus guidelines for minimal residual disease assessment in Philadelphia-positive acute lymphoblastic leukemia (Ph + ALL) by real-time quantitative reverse transcriptase PCR of e1a2 BCR-ABL1.

Pfeifer H, Cazzaniga G, van der Velden VHJ, Cayuela JM, Schäfer B, Spinelli O, Akiki S, Avigad S, Bendit I, Borg K, Cavé H, Elia L, Reshmi SC, Gerrard G, Hayette S, Hermanson M, Juh A, Jurcek T, Chillón MC, Homburg C, Martinelli G, Kairisto V, Lange T, Lion T, Mueller MC, Pane F, Rai L, Damm-Welk C, Sacha T, Schnittger S, Touloumenidou T, Valerhaugen H, Vandenberghe P, Zuna J, Serve H, Herrmann E, Markovic S, Dongen JJMV, Ottmann OG.

Leukemia. 2019 Mar 11. doi: 10.1038/s41375-019-0413-0. [Epub ahead of print]


Application of a Purified Protein From Natural Latex and the Influence of Suture Type on Achilles Tendon Repair in Rats.

Cury DP, Schäfer BT, de Almeida SRY, Righetti MMDS, Watanabe IS.

Am J Sports Med. 2019 Mar;47(4):901-914. doi: 10.1177/0363546518822836. Epub 2019 Feb 13.


USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth.

Gierisch ME, Pedot G, Walser F, Lopez-Garcia LA, Jaaks P, Niggli FK, Schäfer BW.

Sci Rep. 2019 Jan 30;9(1):951. doi: 10.1038/s41598-018-37264-5.


Roll-to-Roll Manufacturing of Micropatterned Adhesives by Template Compression.

Yu D, Beckelmann D, Opsölder M, Schäfer B, Moh K, Hensel R, de Oliveira PW, Arzt E.

Materials (Basel). 2018 Dec 29;12(1). pii: E97. doi: 10.3390/ma12010097.


Duxbling Stem Cells Meet Tumorigenesis.

Schäfer BW.

Cell Stem Cell. 2018 Dec 6;23(6):773-774. doi: 10.1016/j.stem.2018.11.020.


[Echocardiography in Acute Right Heart Insufficiency].

Schäfer B, Greim CA.

Anasthesiol Intensivmed Notfallmed Schmerzther. 2018 Nov;53(11-12):778-786. doi: 10.1055/a-0575-7156. Epub 2018 Nov 20. Review. German.


Structural characterization of four different naturally occurring porcine collagen membranes suitable for medical applications.

Maurer T, Stoffel MH, Belyaev Y, Stiefel NG, Vidondo B, Küker S, Mogel H, Schäfer B, Balmer J.

PLoS One. 2018 Oct 3;13(10):e0205027. doi: 10.1371/journal.pone.0205027. eCollection 2018.


Author Correction: Dynamically induced cascading failures in power grids.

Schäfer B, Witthaut D, Timme M, Latora V.

Nat Commun. 2018 Sep 27;9(1):4032. doi: 10.1038/s41467-018-06483-9.


Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain.

Krauskopf K, Gebel J, Kazemi S, Tuppi M, Löhr F, Schäfer B, Koch J, Güntert P, Dötsch V, Kehrloesser S.

Structure. 2018 Aug 7;26(8):1091-1100.e4. doi: 10.1016/j.str.2018.05.013. Epub 2018 Jun 28.


Diverse migration strategies in hoopoes (Upupa epops) lead to weak spatial but strong temporal connectivity.

van Wijk RE, Schaub M, Hahn S, Juárez-García-Pelayo N, Schäfer B, Viktora L, Martín-Vivaldi M, Zischewski M, Bauer S.

Naturwissenschaften. 2018 Jun 21;105(7-8):42. doi: 10.1007/s00114-018-1566-9.


Motivational Reasons for Biased Decisions: The Sunk-Cost Effect's Instrumental Rationality.

Domeier M, Sachse P, Schäfer B.

Front Psychol. 2018 May 24;9:815. doi: 10.3389/fpsyg.2018.00815. eCollection 2018.


Dynamically induced cascading failures in power grids.

Schäfer B, Witthaut D, Timme M, Latora V.

Nat Commun. 2018 May 17;9(1):1975. doi: 10.1038/s41467-018-04287-5. Erratum in: Nat Commun. 2018 Sep 27;9(1):4032.


Author Correction: Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology.

Kim JK, Louhghalam A, Lee G, Schafer BW, Wirtz D, Kim DH.

Nat Commun. 2018 Mar 13;9(1):1115. doi: 10.1038/s41467-018-03450-2.


Risk assessment of pyrrolizidine alkaloids in food of plant and animal origin.

Dusemund B, Nowak N, Sommerfeld C, Lindtner O, Schäfer B, Lampen A.

Food Chem Toxicol. 2018 May;115:63-72. doi: 10.1016/j.fct.2018.03.005. Epub 2018 Mar 7. Review.


Usage of FT-ICR-MS Metabolomics for Characterizing the Chemical Signatures of Barrel-Aged Whisky.

Roullier-Gall C, Signoret J, Hemmler D, Witting MA, Kanawati B, Schäfer B, Gougeon RD, Schmitt-Kopplin P.

Front Chem. 2018 Feb 22;6:29. doi: 10.3389/fchem.2018.00029. eCollection 2018.


Opposite Surface and Bulk Solvatochromic Effects in a Molecular Spin-Crossover Compound Revealed by Ambient Pressure X-ray Absorption Spectroscopy.

Borgatti F, Torelli P, Brucale M, Gentili D, Panaccione G, Castan Guerrero C, Schäfer B, Ruben M, Cavallini M.

Langmuir. 2018 Mar 27;34(12):3604-3609. doi: 10.1021/acs.langmuir.8b00028. Epub 2018 Mar 12.


Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63.

Tuppi M, Kehrloesser S, Coutandin DW, Rossi V, Luh LM, Strubel A, Hötte K, Hoffmeister M, Schäfer B, De Oliveira T, Greten F, Stelzer EHK, Knapp S, De Felici M, Behrends C, Klinger FG, Dötsch V.

Nat Struct Mol Biol. 2018 Mar;25(3):261-269. doi: 10.1038/s41594-018-0035-7. Epub 2018 Feb 26.


Synthesis, Characterization, and Computational Modeling of N-(1-Ethoxyvinyl)pyridinium Triflates, an Unusual Class of Pyridinium Salts.

Shapiro JD, Sonberg JC, Schafer BC, Williams CC, Ferris HR, Reinheimer EW, Van Wynsberghe AW, Kriley CE, Majireck MM.

Molecules. 2018 Feb 14;23(2). pii: E413. doi: 10.3390/molecules23020413.


Food and feed safety of DAS-444Ø6-6 herbicide-tolerant soybean.

Herman RA, Ekmay RD, Schafer BW, Song P, Fast BJ, Papineni S, Shan G, Juberg DR.

Regul Toxicol Pharmacol. 2018 Apr;94:70-74. doi: 10.1016/j.yrtph.2018.01.016. Epub 2018 Jan 28. Review.


Protein aggregation of the p63 transcription factor underlies severe skin fragility in AEC syndrome.

Russo C, Osterburg C, Sirico A, Antonini D, Ambrosio R, Würz JM, Rinnenthal J, Ferniani M, Kehrloesser S, Schäfer B, Güntert P, Sinha S, Dötsch V, Missero C.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E906-E915. doi: 10.1073/pnas.1713773115. Epub 2018 Jan 16.


AI4People-An Ethical Framework for a Good AI Society: Opportunities, Risks, Principles, and Recommendations.

Floridi L, Cowls J, Beltrametti M, Chatila R, Chazerand P, Dignum V, Luetge C, Madelin R, Pagallo U, Rossi F, Schafer B, Valcke P, Vayena E.

Minds Mach (Dordr). 2018;28(4):689-707. doi: 10.1007/s11023-018-9482-5. Epub 2018 Nov 26.


[Acute perioperative right heart insufficiency : Diagnostics and treatment].

Schäfer B, Greim CA.

Anaesthesist. 2018 Jan;67(1):61-78. doi: 10.1007/s00101-017-0394-1. German.


Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology.

Kim JK, Louhghalam A, Lee G, Schafer BW, Wirtz D, Kim DH.

Nat Commun. 2017 Dec 14;8(1):2123. doi: 10.1038/s41467-017-02217-5. Erratum in: Nat Commun. 2018 Mar 13;9(1):1115.


Safety and accuracy of 68Ga-DOTATOC PET/CT in children and young adults with solid tumors.

Abongwa C, Mott S, Schafer B, McNeely P, Abusin G, O'Dorisio T, Zamba G, O'Dorisio MS, Menda Y.

Am J Nucl Med Mol Imaging. 2017 Nov 1;7(5):228-235. eCollection 2017.


Reduced-Intensity Delayed Intensification in Standard-Risk Pediatric Acute Lymphoblastic Leukemia Defined by Undetectable Minimal Residual Disease: Results of an International Randomized Trial (AIEOP-BFM ALL 2000).

Schrappe M, Bleckmann K, Zimmermann M, Biondi A, Möricke A, Locatelli F, Cario G, Rizzari C, Attarbaschi A, Valsecchi MG, Bartram CR, Barisone E, Niggli F, Niemeyer C, Testi AM, Mann G, Ziino O, Schäfer B, Panzer-Grümayer R, Beier R, Parasole R, Göhring G, Ludwig WD, Casale F, Schlegel PG, Basso G, Conter V.

J Clin Oncol. 2018 Jan 20;36(3):244-253. doi: 10.1200/JCO.2017.74.4946. Epub 2017 Nov 17.


PAX3-FOXO1: Zooming in on an "undruggable" target.

Wachtel M, Schäfer BW.

Semin Cancer Biol. 2018 Jun;50:115-123. doi: 10.1016/j.semcancer.2017.11.006. Epub 2017 Nov 14. Review.


Safety Aspects of the Use of Quercetin as a Dietary Supplement.

Andres S, Pevny S, Ziegenhagen R, Bakhiya N, Schäfer B, Hirsch-Ernst KI, Lampen A.

Mol Nutr Food Res. 2018 Jan;62(1). doi: 10.1002/mnfr.201700447. Epub 2017 Dec 19. Review.


Morphological Characterization of the Myenteric Plexus of the Ileum and Distal colon of Dogs Affected by Muscular Dystrophy.

SchÄfer BT, Silveira MP, Palombit K, Mendes CE, Watanabe IS, Miglino MA, Castelucci P.

Anat Rec (Hoboken). 2018 Apr;301(4):673-685. doi: 10.1002/ar.23708. Epub 2017 Nov 11.


Passive compensation of laser-induced higher-order aberrations in high-power NIR optics.

Stubenvoll M, Schäfer B, Mann K.

Opt Express. 2017 Oct 16;25(21):25407-25415. doi: 10.1364/OE.25.025407.


Examination of anonymous canine faecal samples provides data on endoparasite prevalence rates in dogs for comparative studies.

Hinney B, Gottwald M, Moser J, Reicher B, Schäfer BJ, Schaper R, Joachim A, Künzel F.

Vet Parasitol. 2017 Oct 15;245:106-115. doi: 10.1016/j.vetpar.2017.08.016. Epub 2017 Aug 25.


Answer to the Letter to the Editor of Dr. Clouatre and Dr. Preuss.

Bakhiya N, Ziegenhagen R, Hirsch-Ernst KI, Dusemund B, Richter K, Schultrich K, Pevny S, Schäfer B, Lampen A.

Mol Nutr Food Res. 2017 Sep;61(9). doi: 10.1002/mnfr.201770095. No abstract available.


Measurement of lipid transfer proteins in genetically engineered maize using liquid chromatography with tandem mass spectrometry (LC-MS/MS).

Hill RC, Wang X, Schafer BW, Gampala SS, Herman RA.

GM Crops Food. 2017 Oct 2;8(4):239-252. doi: 10.1080/21645698.2017.1349602. Epub 2017 Aug 28.


Thy-1+/- fibroblast subsets in the human peritoneum.

Kawka E, Witowski J, Bartosova M, Catar R, Rudolf A, Philippe A, Rutkowski R, Schäfer B, Schmitt CP, Dragun D, Jörres A.

Am J Physiol Renal Physiol. 2017 Nov 1;313(5):F1116-F1123. doi: 10.1152/ajprenal.00274.2017. Epub 2017 Jul 19.


Escape routes, weak links, and desynchronization in fluctuation-driven networks.

Schäfer B, Matthiae M, Zhang X, Rohden M, Timme M, Witthaut D.

Phys Rev E. 2017 Jun;95(6-1):060203. doi: 10.1103/PhysRevE.95.060203. Epub 2017 Jun 9.


The MLL recombinome of acute leukemias in 2017.

Meyer C, Burmeister T, Gröger D, Tsaur G, Fechina L, Renneville A, Sutton R, Venn NC, Emerenciano M, Pombo-de-Oliveira MS, Barbieri Blunck C, Almeida Lopes B, Zuna J, Trka J, Ballerini P, Lapillonne H, De Braekeleer M, Cazzaniga G, Corral Abascal L, van der Velden VHJ, Delabesse E, Park TS, Oh SH, Silva MLM, Lund-Aho T, Juvonen V, Moore AS, Heidenreich O, Vormoor J, Zerkalenkova E, Olshanskaya Y, Bueno C, Menendez P, Teigler-Schlegel A, Zur Stadt U, Lentes J, Göhring G, Kustanovich A, Aleinikova O, Schäfer BW, Kubetzko S, Madsen HO, Gruhn B, Duarte X, Gameiro P, Lippert E, Bidet A, Cayuela JM, Clappier E, Alonso CN, Zwaan CM, van den Heuvel-Eibrink MM, Izraeli S, Trakhtenbrot L, Archer P, Hancock J, Möricke A, Alten J, Schrappe M, Stanulla M, Strehl S, Attarbaschi A, Dworzak M, Haas OA, Panzer-Grümayer R, Sedék L, Szczepański T, Caye A, Suarez L, Cavé H, Marschalek R.

Leukemia. 2018 Feb;32(2):273-284. doi: 10.1038/leu.2017.213. Epub 2017 Jul 13.


Development, Validation, and Interlaboratory Evaluation of a Quantitative Multiplexing Method To Assess Levels of Ten Endogenous Allergens in Soybean Seed and Its Application to Field Trials Spanning Three Growing Seasons.

Hill RC, Oman TJ, Wang X, Shan G, Schafer B, Herman RA, Tobias R, Shippar J, Malayappan B, Sheng L, Xu A, Bradshaw J.

J Agric Food Chem. 2017 Jul 12;65(27):5531-5544. doi: 10.1021/acs.jafc.7b01018. Epub 2017 Jun 29.


[Heat-induced contaminants in foodstuffs : Acrylamide, furan, and fatty acid esters of monochloropropanediols and glycidol].

Andres S, Schultrich K, Monien B, Buhrke T, Bakhiya N, Frenzel F, Abraham K, Schäfer B, Lampen A.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2017 Jul;60(7):737-744. doi: 10.1007/s00103-017-2564-3. Review. German.


Affine and non-affine deformations quantified in cytoskeletal networks through three-dimensional form-finding model.

Wang Y, Gong J, Wirtz D, Schafer BW.

J Mech Behav Biomed Mater. 2017 Aug;72:52-65. doi: 10.1016/j.jmbbm.2017.04.015. Epub 2017 Apr 20.


Phytochemical compounds in sport nutrition: Synephrine and hydroxycitric acid (HCA) as examples for evaluation of possible health risks.

Bakhiya N, Ziegenhagen R, Hirsch-Ernst KI, Dusemund B, Richter K, Schultrich K, Pevny S, Schäfer B, Lampen A.

Mol Nutr Food Res. 2017 Jun;61(6). doi: 10.1002/mnfr.201601020. Epub 2017 May 2. Review.


Stacking transgenic event DAS-Ø15Ø7-1 alters maize composition less than traditional breeding.

Herman RA, Fast BJ, Scherer PN, Brune AM, de Cerqueira DT, Schafer BW, Ekmay RD, Harrigan GG, Bradfisch GA.

Plant Biotechnol J. 2017 Oct;15(10):1264-1272. doi: 10.1111/pbi.12713. Epub 2017 Apr 11.


Correlation of the structural information obtained for europium-chelate ensembles from gas-phase photoluminescence and ion-mobility spectroscopy with density-functional computations and ligand-field theory.

Greisch JF, Chmela J, Harding ME, Wunderlich D, Schäfer B, Ruben M, Klopper W, Schooss D, Kappes MM.

Phys Chem Chem Phys. 2017 Feb 22;19(8):6105-6112. doi: 10.1039/c6cp04656h.


A luminescent Pt2Fe spin crossover complex.

Schäfer B, Bauer T, Faus I, Wolny JA, Dahms F, Fuhr O, Lebedkin S, Wille HC, Schlage K, Chevalier K, Rupp F, Diller R, Schünemann V, Kappes MM, Ruben M.

Dalton Trans. 2017 Feb 14;46(7):2289-2302. doi: 10.1039/c6dt04360g.


[Risk assessment of synephrine in dietary supplements].

Bakhyia N, Dusemund B, Richter K, Lindtner O, Hirsch-Ernst KI, Schäfer B, Lampen A.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2017 Mar;60(3):323-331. doi: 10.1007/s00103-016-2506-5. Review. German.


Creatine and creatine forms intended for sports nutrition.

Andres S, Ziegenhagen R, Trefflich I, Pevny S, Schultrich K, Braun H, Schänzer W, Hirsch-Ernst KI, Schäfer B, Lampen A.

Mol Nutr Food Res. 2017 Jun;61(6). doi: 10.1002/mnfr.201600772. Epub 2017 Mar 30. Review.


Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue.

Gierisch ME, Pfistner F, Lopez-Garcia LA, Harder L, Schäfer BW, Niggli FK.

J Biol Chem. 2016 Dec 23;291(52):26922-26933. doi: 10.1074/jbc.M116.752063. Epub 2016 Nov 8.


Controlled manipulation of the Co-Alq3 interface by rational design of Alq3 derivatives.

Großmann N, Magri A, Laux M, Stadtmüller B, Thielen P, Schäfer B, Fuhr O, Ruben M, Cinchetti M, Aeschlimann M.

Dalton Trans. 2016 Nov 15;45(45):18365-18376.


Helicase CHD4 is an epigenetic coregulator of PAX3-FOXO1 in alveolar rhabdomyosarcoma.

Böhm M, Wachtel M, Marques JG, Streiff N, Laubscher D, Nanni P, Mamchaoui K, Santoro R, Schäfer BW.

J Clin Invest. 2016 Nov 1;126(11):4237-4249. doi: 10.1172/JCI85057. Epub 2016 Oct 17.


Rapid simulated gastric fluid digestion of in-seed/grain proteins expressed in genetically engineered crops.

Schafer BW, Embrey SK, Herman RA.

Regul Toxicol Pharmacol. 2016 Nov;81:106-112. doi: 10.1016/j.yrtph.2016.08.004. Epub 2016 Aug 4.


Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization.

Gebel J, Luh LM, Coutandin D, Osterburg C, Löhr F, Schäfer B, Frombach AS, Sumyk M, Buchner L, Krojer T, Salah E, Mathea S, Güntert P, Knapp S, Dötsch V.

Cell Death Differ. 2016 Dec;23(12):1930-1940. doi: 10.1038/cdd.2016.83. Epub 2016 Oct 7.

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