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Items: 13

1.

Loss of PRC1 activity in different stem cell compartments activates a common transcriptional program with cell type-dependent outcomes.

Pivetti S, Fernandez-Perez D, D'Ambrosio A, Barbieri CM, Manganaro D, Rossi A, Barnabei L, Zanotti M, Scelfo A, Chiacchiera F, Pasini D.

Sci Adv. 2019 May 15;5(5):eaav1594. doi: 10.1126/sciadv.aav1594. eCollection 2019 May.

2.

Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities.

Scelfo A, Fernández-Pérez D, Tamburri S, Zanotti M, Lavarone E, Soldi M, Bonaldi T, Ferrari KJ, Pasini D.

Mol Cell. 2019 Jun 6;74(5):1037-1052.e7. doi: 10.1016/j.molcel.2019.04.002. Epub 2019 Apr 24.

3.

Phosphorylation of CENP-A on serine 7 does not control centromere function.

Barra V, Logsdon GA, Scelfo A, Hoffmann S, Hervé S, Aslanian A, Nechemia-Arbely Y, Cleveland DW, Black BE, Fachinetti D.

Nat Commun. 2019 Jan 11;10(1):175. doi: 10.1038/s41467-018-08073-1.

4.

The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells.

Streubel G, Watson A, Jammula SG, Scelfo A, Fitzpatrick DJ, Oliviero G, McCole R, Conway E, Glancy E, Negri GL, Dillon E, Wynne K, Pasini D, Krogan NJ, Bracken AP, Cagney G.

Mol Cell. 2018 Apr 19;70(2):371-379.e5. doi: 10.1016/j.molcel.2018.02.027. Epub 2018 Mar 29.

5.

Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.

Streubel G, Fitzpatrick DJ, Oliviero G, Scelfo A, Moran B, Das S, Munawar N, Watson A, Wynne K, Negri GL, Dillon ET, Jammula S, Hokamp K, O'Connor DP, Pasini D, Cagney G, Bracken AP.

EMBO J. 2017 Aug 1;36(15):2216-2232. doi: 10.15252/embj.201696307. Epub 2017 May 29.

6.

Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice.

Rossi A, Ferrari KJ, Piunti A, Jammula S, Chiacchiera F, Mazzarella L, Scelfo A, Pelicci PG, Pasini D.

Sci Adv. 2016 Oct 7;2(10):e1600972. eCollection 2016 Oct.

7.

Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/β-Catenin Transcriptional Activity.

Chiacchiera F, Rossi A, Jammula S, Piunti A, Scelfo A, Ordóñez-Morán P, Huelsken J, Koseki H, Pasini D.

Cell Stem Cell. 2016 Jan 7;18(1):91-103. doi: 10.1016/j.stem.2015.09.019. Epub 2015 Oct 29.

8.

The controversial role of the Polycomb group proteins in transcription and cancer: how much do we not understand Polycomb proteins?

Scelfo A, Piunti A, Pasini D.

FEBS J. 2015 May;282(9):1703-22. doi: 10.1111/febs.13112. Epub 2014 Nov 11. Review.

9.

A novel self-lipid antigen targets human T cells against CD1c(+) leukemias.

Lepore M, de Lalla C, Gundimeda SR, Gsellinger H, Consonni M, Garavaglia C, Sansano S, Piccolo F, Scelfo A, Häussinger D, Montagna D, Locatelli F, Bonini C, Bondanza A, Forcina A, Li Z, Ni G, Ciceri F, Jenö P, Xia C, Mori L, Dellabona P, Casorati G, De Libero G.

J Exp Med. 2014 Jun 30;211(7):1363-77. doi: 10.1084/jem.20140410. Epub 2014 Jun 16.

10.

Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication.

Piunti A, Rossi A, Cerutti A, Albert M, Jammula S, Scelfo A, Cedrone L, Fragola G, Olsson L, Koseki H, Testa G, Casola S, Helin K, d'Adda di Fagagna F, Pasini D.

Nat Commun. 2014 Apr 14;5:3649. doi: 10.1038/ncomms4649.

11.

Polycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelity.

Ferrari KJ, Scelfo A, Jammula S, Cuomo A, Barozzi I, Stützer A, Fischle W, Bonaldi T, Pasini D.

Mol Cell. 2014 Jan 9;53(1):49-62. doi: 10.1016/j.molcel.2013.10.030. Epub 2013 Nov 27.

12.

Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells.

Vella P, Scelfo A, Jammula S, Chiacchiera F, Williams K, Cuomo A, Roberto A, Christensen J, Bonaldi T, Helin K, Pasini D.

Mol Cell. 2013 Feb 21;49(4):645-56. doi: 10.1016/j.molcel.2012.12.019. Epub 2013 Jan 24.

13.

High-frequency and adaptive-like dynamics of human CD1 self-reactive T cells.

de Lalla C, Lepore M, Piccolo FM, Rinaldi A, Scelfo A, Garavaglia C, Mori L, De Libero G, Dellabona P, Casorati G.

Eur J Immunol. 2011 Mar;41(3):602-10. doi: 10.1002/eji.201041211. Epub 2011 Jan 18.

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