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Items: 12


Two drugs converged in a pancreatic β cell.

Scavuzzo MA, Borowiak M.

Sci Transl Med. 2020 Feb 12;12(530). pii: eaba7359. doi: 10.1126/scitranslmed.aba7359. Review.


A Critical Insulin TCR Contact Residue Selects High Affinity and Pathogenic Insulin Specific T Cells.

Bettini M, Scavuzzo MA, Liu B, Kolawole E, Guo L, Evavold BD, Borowiak M, Bettini ML.

Diabetes. 2019 Dec 13. pii: db190821. doi: 10.2337/db19-0821. [Epub ahead of print]


Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA.

Scavuzzo MA, Chmielowiec J, Yang D, Wamble K, Chaboub LS, Duraine L, Tepe B, Glasgow SM, Arenkiel BR, Brou C, Deneen B, Borowiak M.

Cell Rep. 2018 Dec 26;25(13):3811-3827.e7. doi: 10.1016/j.celrep.2018.11.078.


Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis.

Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M.

Nat Commun. 2018 Aug 22;9(1):3356. doi: 10.1038/s41467-018-05740-1.


Generation of Scaffold-free, Three-dimensional Insulin Expressing Pancreatoids from Mouse Pancreatic Progenitors In Vitro.

Scavuzzo MA, Teaw J, Yang D, Borowiak M.

J Vis Exp. 2018 Jun 2;(136). doi: 10.3791/57599.


High self-reactivity drives T-bet and potentiates Treg function in tissue-specific autoimmunity.

Sprouse ML, Scavuzzo MA, Blum S, Shevchenko I, Lee T, Makedonas G, Borowiak M, Bettini ML, Bettini M.

JCI Insight. 2018 Jan 25;3(2). pii: 97322. doi: 10.1172/jci.insight.97322. eCollection 2018 Jan 25.


Cutting Edge: Low-Affinity TCRs Support Regulatory T Cell Function in Autoimmunity.

Sprouse ML, Shevchenko I, Scavuzzo MA, Joseph F, Lee T, Blum S, Borowiak M, Bettini ML, Bettini M.

J Immunol. 2018 Feb 1;200(3):909-914. doi: 10.4049/jimmunol.1700156. Epub 2017 Dec 27.


Organotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells.

Scavuzzo MA, Yang D, Borowiak M.

Sci Rep. 2017 Sep 7;7(1):10810. doi: 10.1038/s41598-017-11169-1.


Editing genetics, stem cells are prophetic, what's the best way to model cells of diabetics?

Scavuzzo MA, Borowiak M.

Stem Cell Investig. 2016 Nov 15;3:81. doi: 10.21037/sci.2016.11.02. eCollection 2016. No abstract available.


Enrichment of G2/M cell cycle phase in human pluripotent stem cells enhances HDR-mediated gene repair with customizable endonucleases.

Yang D, Scavuzzo MA, Chmielowiec J, Sharp R, Bajic A, Borowiak M.

Sci Rep. 2016 Feb 18;6:21264. doi: 10.1038/srep21264.


Rbfox2-coordinated alternative splicing of Mef2d and Rock2 controls myoblast fusion during myogenesis.

Singh RK, Xia Z, Bland CS, Kalsotra A, Scavuzzo MA, Curk T, Ule J, Li W, Cooper TA.

Mol Cell. 2014 Aug 21;55(4):592-603. doi: 10.1016/j.molcel.2014.06.035. Epub 2014 Jul 31.


Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development.

Giudice J, Xia Z, Wang ET, Scavuzzo MA, Ward AJ, Kalsotra A, Wang W, Wehrens XH, Burge CB, Li W, Cooper TA.

Nat Commun. 2014 Apr 22;5:3603. doi: 10.1038/ncomms4603.

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