Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 25

1.

Phase I study of orally administered 14Carbon-isotope labelled-vistusertib (AZD2014), a dual TORC1/2 kinase inhibitor, to assess the absorption, metabolism, excretion, and pharmacokinetics in patients with advanced solid malignancies.

MacDonald A, Scarfe G, Magirr D, Sarvotham T, Charlton J, Brugger W, Dean E.

Cancer Chemother Pharmacol. 2019 Apr;83(4):787-795. doi: 10.1007/s00280-019-03781-x. Epub 2019 Feb 13.

PMID:
30758651
2.

Physiologically Based Pharmacokinetic Modeling for Olaparib Dosing Recommendations: Bridging Formulations, Drug Interactions, and Patient Populations.

Pilla Reddy V, Bui K, Scarfe G, Zhou D, Learoyd M.

Clin Pharmacol Ther. 2019 Jan;105(1):229-241. doi: 10.1002/cpt.1103. Epub 2018 Aug 9.

3.

CYP-Mediated Sulfoximine Deimination of AZD6738.

Jones BC, Markandu R, Gu C, Scarfe G.

Drug Metab Dispos. 2017 Nov;45(11):1133-1138. doi: 10.1124/dmd.117.077776. Epub 2017 Aug 23.

PMID:
28835442
4.

In vitro evaluation of the inhibition and induction potential of olaparib, a potent poly(ADP-ribose) polymerase inhibitor, on cytochrome P450.

McCormick A, Swaisland H, Reddy VP, Learoyd M, Scarfe G.

Xenobiotica. 2018 Jun;48(6):555-564. doi: 10.1080/00498254.2017.1346332. Epub 2017 Jul 25.

PMID:
28657402
5.

Pharmacokinetics, absorption, and excretion of radiolabeled revexepride: a Phase I clinical trial using a microtracer and accelerator mass spectrometry-based approach.

Flach S, Croft M, Ding J, Budhram R, Pankratz T, Pennick M, Scarfe G, Troy S, Getsy J.

Drug Des Devel Ther. 2016 Sep 27;10:3125-3132. eCollection 2016.

6.

A Phase I Study to Investigate the Absorption, Pharmacokinetics, and Excretion of [(14)C]Prucalopride After a Single Oral Dose in Healthy Volunteers.

Flach S, Scarfe G, Dragone J, Ding J, Seymour M, Pennick M, Pankratz T, Troy S, Getsy J.

Clin Ther. 2016 Sep;38(9):2106-15. doi: 10.1016/j.clinthera.2016.08.003. Epub 2016 Sep 7.

7.

Appreciation of a Child's Journey: Implementation of a Cardiac Action Research Project.

Dengler KA, Wilson V, Redshaw S, Scarfe G.

Nurs Res Pract. 2012;2012:145030. doi: 10.1155/2012/145030. Epub 2012 Apr 29.

8.

Heart to heart: a programme for children on a cardiac ward.

Scarfe G, Redshaw S, Wilson V, Dengler L.

Br J Nurs. 2012 Jan 26-Feb 8;21(2):108, 110-2, 114.

PMID:
22306638
9.

Narratives of the heart: telling the story of children with a cardiac condition through a bead program.

Redshaw S, Wilson V, Scarfe G, Dengler L.

J Clin Nurs. 2011 Oct;20(19-20):2802-11. doi: 10.1111/j.1365-2702.2011.03780.x. Epub 2011 Jun 27.

PMID:
21702864
10.

Hypoplastic left heart syndrome in context.

Winlaw DS, Badawi N, Jacobe S, Kasparian NA, Cooper SG, Murphy DN, Sherwood MC, Roberts P, Leclair K, Scarfe G, Sholler GF.

J Paediatr Child Health. 2012 Feb;48(2):E7-9. doi: 10.1111/j.1440-1754.2011.02084.x. Epub 2011 Apr 29.

PMID:
21535290
11.

Five-year analysis of operative mortality and neonatal outcomes in congenital heart disease.

Padley JR, Cole AD, Pye VE, Chard RB, Nicholson IA, Jacobe S, Baines D, Badawi N, Walker K, Scarfe G, Leclair K, Sholler GF, Winlaw DS.

Heart Lung Circ. 2011 Jul;20(7):460-7. doi: 10.1016/j.hlc.2011.03.009. Epub 2011 Apr 21.

PMID:
21514216
12.

The heart beads program.

Dengler KA, Scarfe G, Redshaw S, Wilson V.

J Spec Pediatr Nurs. 2011 Jan;16(1):80-4. doi: 10.1111/j.1744-6155.2010.00273.x.

PMID:
21294839
13.

Virtual chromatographic resolution enhancement in cryoflow LC-NMR experiments via statistical total correlation spectroscopy.

Cloarec O, Campbell A, Tseng LH, Braumann U, Spraul M, Scarfe G, Weaver R, Nicholson JK.

Anal Chem. 2007 May 1;79(9):3304-11. Epub 2007 Mar 30.

PMID:
17394288
14.
15.

Identification of the urinary metabolites of 4-bromoaniline and 4-bromo-[carbonyl-13C]-acetanilide in rat.

Scarfe GB, Nicholson JK, Lindon JC, Wilson ID, Taylor S, Clayton E, Wright B.

Xenobiotica. 2002 Apr;32(4):325-37.

PMID:
12028665
16.

Structure-metabolism relationships of substituted anilines: prediction of N-acetylation and N-oxanilic acid formation using computational chemistry.

Scarfe GB, Wilson ID, Warne MA, Holmes E, Nicholson JK, Lindon JC.

Xenobiotica. 2002 Apr;32(4):267-77.

PMID:
12028661
19.

Investigation of the metabolism of 14C/13C-practolol in rat using directly coupled radio-HPLC-NMR-MS.

Scarfe GB, Lindon JC, Nicholson JK, Martin P, Wright B, Taylor S, Lenz E, Wilson ID.

Xenobiotica. 2000 Jul;30(7):717-29.

PMID:
10963062
20.
21.

Investigation of the quantitative metabolic fate and urinary excretion of 3-methyl-4-trifluoromethylaniline and 3-methyl-4-trifluoromethylacetanilide in the rat.

Scarfe GB, Lindon JC, Nicholson JK, Wright B, Clayton E, Wilson ID.

Drug Metab Dispos. 1999 Oct;27(10):1171-8.

PMID:
10497144
22.

Directly coupled CZE-NMR and CEC-NMR spectroscopy for metabolite analysis: paracetamol metabolites in human urine.

Schewitz J, Gfrörer P, Pusecker K, Tseng LH, Albert K, Bayer E, Wilson ID, Bailey NJ, Scarfe GB, Nicholson JK, Lindon JC.

Analyst. 1998 Dec;123(12):2835-7.

PMID:
10435347
24.

Quantitative studies on the urinary metabolic fate of 2-chloro-4-trifluoromethylaniline in the rat using 19F-NMR spectroscopy and directly coupled HPLC-NMR-MS.

Scarfe GB, Wright B, Clayton E, Taylor S, Wilson ID, Lindon JC, Nicholson JK.

Xenobiotica. 1999 Jan;29(1):77-91.

PMID:
10078841
25.

Supplemental Content

Loading ...
Support Center