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Items: 47

1.

Subtomogram averaging from cryo-electron tomograms.

Leigh KE, Navarro PP, Scaramuzza S, Chen W, Zhang Y, Castaño-Díez D, Kudryashev M.

Methods Cell Biol. 2019;152:217-259. doi: 10.1016/bs.mcb.2019.04.003. Epub 2019 May 15.

PMID:
31326022
2.

Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study.

Ferrua F, Cicalese MP, Galimberti S, Giannelli S, Dionisio F, Barzaghi F, Migliavacca M, Bernardo ME, Calbi V, Assanelli AA, Facchini M, Fossati C, Albertazzi E, Scaramuzza S, Brigida I, Scala S, Basso-Ricci L, Pajno R, Casiraghi M, Canarutto D, Salerio FA, Albert MH, Bartoli A, Wolf HM, Fiori R, Silvani P, Gattillo S, Villa A, Biasco L, Dott C, Culme-Seymour EJ, van Rossem K, Atkinson G, Valsecchi MG, Roncarolo MG, Ciceri F, Naldini L, Aiuti A.

Lancet Haematol. 2019 May;6(5):e239-e253. doi: 10.1016/S2352-3026(19)30021-3. Epub 2019 Apr 10.

3.

Mitotic replisome disassembly depends on TRAIP ubiquitin ligase activity.

Priego Moreno S, Jones RM, Poovathumkadavil D, Scaramuzza S, Gambus A.

Life Sci Alliance. 2019 Apr 12;2(2). pii: e201900390. doi: 10.26508/lsa.201900390. Print 2019 Apr.

4.

Bone marrow stromal cells from β-thalassemia patients have impaired hematopoietic supportive capacity.

Crippa S, Rossella V, Aprile A, Silvestri L, Rivis S, Scaramuzza S, Pirroni S, Avanzini MA, Basso-Ricci L, Hernandez RJ, Zecca M, Marktel S, Ciceri F, Aiuti A, Ferrari G, Bernardo ME.

J Clin Invest. 2019 Feb 25;129(4):1566-1580. doi: 10.1172/JCI123191. eCollection 2019 Feb 25.

5.

Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ß-thalassemia.

Marktel S, Scaramuzza S, Cicalese MP, Giglio F, Galimberti S, Lidonnici MR, Calbi V, Assanelli A, Bernardo ME, Rossi C, Calabria A, Milani R, Gattillo S, Benedicenti F, Spinozzi G, Aprile A, Bergami A, Casiraghi M, Consiglieri G, Masera N, D'Angelo E, Mirra N, Origa R, Tartaglione I, Perrotta S, Winter R, Coppola M, Viarengo G, Santoleri L, Graziadei G, Gabaldo M, Valsecchi MG, Montini E, Naldini L, Cappellini MD, Ciceri F, Aiuti A, Ferrari G.

Nat Med. 2019 Feb;25(2):234-241. doi: 10.1038/s41591-018-0301-6. Epub 2019 Jan 21.

PMID:
30664781
6.

Circulating and Synovial Fluid Heat Shock Protein 70 Are Correlated with Severity in Knee Osteoarthritis.

Ngarmukos S, Scaramuzza S, Theerawattanapong N, Tanavalee A, Honsawek S.

Cartilage. 2018 Jul 1:1947603518790075. doi: 10.1177/1947603518790075. [Epub ahead of print]

PMID:
30024275
7.

Ultra-performance liquid chromatography/multiple reaction monitoring mass spectrometry quantification of trastuzumab in human serum by selective monitoring of a specific peptide marker from the antibody complementarity-determining regions.

Russo R, Rega C, Caporale A, Tonon G, Scaramuzza S, Selis F, Ruvo M, Chambery A.

Rapid Commun Mass Spectrom. 2017 Jul 30;31(14):1184-1192. doi: 10.1002/rcm.7898.

PMID:
28488747
8.

Formation of alloy nanoparticles by laser ablation of Au/Fe multilayer films in liquid environment.

Amendola V, Scaramuzza S, Carraro F, Cattaruzza E.

J Colloid Interface Sci. 2017 Mar 1;489:18-27. doi: 10.1016/j.jcis.2016.10.023. Epub 2016 Oct 13.

PMID:
27770998
9.

Magnetically Assembled SERS Substrates Composed of Iron-Silver Nanoparticles Obtained by Laser Ablation in Liquid.

Scaramuzza S, Badocco D, Pastore P, Coral DF, Fernández van Raap MB, Amendola V.

Chemphyschem. 2017 May 5;18(9):1026-1034. doi: 10.1002/cphc.201600651. Epub 2016 Sep 15.

PMID:
27550553
10.

In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases.

Biasco L, Pellin D, Scala S, Dionisio F, Basso-Ricci L, Leonardelli L, Scaramuzza S, Baricordi C, Ferrua F, Cicalese MP, Giannelli S, Neduva V, Dow DJ, Schmidt M, Von Kalle C, Roncarolo MG, Ciceri F, Vicard P, Wit E, Di Serio C, Naldini L, Aiuti A.

Cell Stem Cell. 2016 Jul 7;19(1):107-19. doi: 10.1016/j.stem.2016.04.016. Epub 2016 May 26.

11.

A novel genomic inversion in Wiskott-Aldrich-associated autoinflammation.

Brigida I, Scaramuzza S, Lazarevic D, Cittaro D, Ferrua F, Leonardelli L, Alessio M, Forma O, Lanzani C, Viarengo G, Ciceri F, Jankovic M, Pesce F, Aiuti A, Cicalese MP.

J Allergy Clin Immunol. 2016 Aug;138(2):619-622.e7. doi: 10.1016/j.jaci.2016.03.007. Epub 2016 Apr 22. No abstract available. Erratum in: J Allergy Clin Immunol. 2017 May;139(5):1721.

12.

Pegylated Trastuzumab Fragments Acquire an Increased in Vivo Stability but Show a Largely Reduced Affinity for the Target Antigen.

Selis F, Focà G, Sandomenico A, Marra C, Di Mauro C, Saccani Jotti G, Scaramuzza S, Politano A, Sanna R, Ruvo M, Tonon G.

Int J Mol Sci. 2016 Apr 1;17(4):491. doi: 10.3390/ijms17040491.

13.

High-level expression of a recombinant active microbial transglutaminase in Escherichia coli.

Salis B, Spinetti G, Scaramuzza S, Bossi M, Saccani Jotti G, Tonon G, Crobu D, Schrepfer R.

BMC Biotechnol. 2015 Sep 15;15:84. doi: 10.1186/s12896-015-0202-4.

14.

Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients.

Pala F, Morbach H, Castiello MC, Schickel JN, Scaramuzza S, Chamberlain N, Cassani B, Glauzy S, Romberg N, Candotti F, Aiuti A, Bosticardo M, Villa A, Meffre E.

J Clin Invest. 2015 Oct 1;125(10):3941-51. doi: 10.1172/JCI82249. Epub 2015 Sep 14.

15.

Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.

Neri T, Muggeo S, Paulis M, Caldana ME, Crisafulli L, Strina D, Focarelli ML, Faggioli F, Recordati C, Scaramuzza S, Scanziani E, Mantero S, Buracchi C, Sobacchi C, Lombardo A, Naldini L, Vezzoni P, Villa A, Ficara F.

Stem Cell Reports. 2015 Oct 13;5(4):558-68. doi: 10.1016/j.stemcr.2015.08.005. Epub 2015 Sep 3.

16.

B-cell reconstitution after lentiviral vector-mediated gene therapy in patients with Wiskott-Aldrich syndrome.

Castiello MC, Scaramuzza S, Pala F, Ferrua F, Uva P, Brigida I, Sereni L, van der Burg M, Ottaviano G, Albert MH, Grazia Roncarolo M, Naldini L, Aiuti A, Villa A, Bosticardo M.

J Allergy Clin Immunol. 2015 Sep;136(3):692-702.e2. doi: 10.1016/j.jaci.2015.01.035. Epub 2015 Mar 16.

17.

Metastable alloy nanoparticles, metal-oxide nanocrescents and nanoshells generated by laser ablation in liquid solution: influence of the chemical environment on structure and composition.

Scaramuzza S, Agnoli S, Amendola V.

Phys Chem Chem Phys. 2015 Nov 14;17(42):28076-87. doi: 10.1039/c5cp00279f. Epub 2015 Mar 6.

PMID:
25746398
18.

Dual-regulated lentiviral vector for gene therapy of X-linked chronic granulomatosis.

Chiriaco M, Farinelli G, Capo V, Zonari E, Scaramuzza S, Di Matteo G, Sergi LS, Migliavacca M, Hernandez RJ, Bombelli F, Giorda E, Kajaste-Rudnitski A, Trono D, Grez M, Rossi P, Finocchi A, Naldini L, Gentner B, Aiuti A.

Mol Ther. 2014 Aug;22(8):1472-1483. doi: 10.1038/mt.2014.87. Epub 2014 May 29.

19.

Sphingosine-1-phosphate receptors control B-cell migration through signaling components associated with primary immunodeficiencies, chronic lymphocytic leukemia, and multiple sclerosis.

Sic H, Kraus H, Madl J, Flittner KA, von Münchow AL, Pieper K, Rizzi M, Kienzler AK, Ayata K, Rauer S, Kleuser B, Salzer U, Burger M, Zirlik K, Lougaris V, Plebani A, Römer W, Loeffler C, Scaramuzza S, Villa A, Noguchi E, Grimbacher B, Eibel H.

J Allergy Clin Immunol. 2014 Aug;134(2):420-8. doi: 10.1016/j.jaci.2014.01.037. Epub 2014 Mar 26.

PMID:
24679343
20.

Magneto-plasmonic Au-Fe alloy nanoparticles designed for multimodal SERS-MRI-CT imaging.

Amendola V, Scaramuzza S, Litti L, Meneghetti M, Zuccolotto G, Rosato A, Nicolato E, Marzola P, Fracasso G, Anselmi C, Pinto M, Colombatti M.

Small. 2014 Jun 25;10(12):2476-86. doi: 10.1002/smll.201303372. Epub 2014 Mar 11. Erratum in: Small. 2014 Oct 15;10(19):3823.

PMID:
24619736
21.

Lentiviral vectors for the treatment of primary immunodeficiencies.

Farinelli G, Capo V, Scaramuzza S, Aiuti A.

J Inherit Metab Dis. 2014 Jul;37(4):525-33. doi: 10.1007/s10545-014-9690-y. Epub 2014 Mar 12. Review.

PMID:
24619149
22.

B-cell development and functions and therapeutic options in adenosine deaminase-deficient patients.

Brigida I, Sauer AV, Ferrua F, Giannelli S, Scaramuzza S, Pistoia V, Castiello MC, Barendregt BH, Cicalese MP, Casiraghi M, Brombin C, Puck J, Müller K, Notarangelo LD, Montin D, van Montfrans JM, Roncarolo MG, Traggiai E, van Dongen JJ, van der Burg M, Aiuti A.

J Allergy Clin Immunol. 2014 Mar;133(3):799-806.e10. doi: 10.1016/j.jaci.2013.12.1043. Epub 2014 Feb 5.

23.

Wiskott-Aldrich Syndrome protein deficiency perturbs the homeostasis of B-cell compartment in humans.

Castiello MC, Bosticardo M, Pala F, Catucci M, Chamberlain N, van Zelm MC, Driessen GJ, Pac M, Bernatowska E, Scaramuzza S, Aiuti A, Sauer AV, Traggiai E, Meffre E, Villa A, van der Burg M.

J Autoimmun. 2014 May;50:42-50. doi: 10.1016/j.jaut.2013.10.006. Epub 2013 Dec 25.

24.

Strong dependence of surface plasmon resonance and surface enhanced Raman scattering on the composition of Au-Fe nanoalloys.

Amendola V, Scaramuzza S, Agnoli S, Polizzi S, Meneghetti M.

Nanoscale. 2014;6(3):1423-33. doi: 10.1039/c3nr04995g.

PMID:
24309909
25.

Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.

Aiuti A, Biasco L, Scaramuzza S, Ferrua F, Cicalese MP, Baricordi C, Dionisio F, Calabria A, Giannelli S, Castiello MC, Bosticardo M, Evangelio C, Assanelli A, Casiraghi M, Di Nunzio S, Callegaro L, Benati C, Rizzardi P, Pellin D, Di Serio C, Schmidt M, Von Kalle C, Gardner J, Mehta N, Neduva V, Dow DJ, Galy A, Miniero R, Finocchi A, Metin A, Banerjee PP, Orange JS, Galimberti S, Valsecchi MG, Biffi A, Montini E, Villa A, Ciceri F, Roncarolo MG, Naldini L.

Science. 2013 Aug 23;341(6148):1233151. doi: 10.1126/science.1233151. Epub 2013 Jul 11.

26.

Biophysical characterization of Met-G-CSF: effects of different site-specific mono-pegylations on protein stability and aggregation.

Natalello A, Ami D, Collini M, D'Alfonso L, Chirico G, Tonon G, Scaramuzza S, Schrepfer R, Doglia SM.

PLoS One. 2012;7(8):e42511. doi: 10.1371/journal.pone.0042511. Epub 2012 Aug 8.

27.

A new site-specific monoPEGylated filgrastim derivative prepared by enzymatic conjugation: Production and physicochemical characterization.

Scaramuzza S, Tonon G, Olianas A, Messana I, Schrepfer R, Orsini G, Caliceti P.

J Control Release. 2012 Dec 28;164(3):355-63. doi: 10.1016/j.jconrel.2012.06.026. Epub 2012 Jun 23.

PMID:
22735238
28.

Preclinical safety and efficacy of human CD34(+) cells transduced with lentiviral vector for the treatment of Wiskott-Aldrich syndrome.

Scaramuzza S, Biasco L, Ripamonti A, Castiello MC, Loperfido M, Draghici E, Hernandez RJ, Benedicenti F, Radrizzani M, Salomoni M, Ranzani M, Bartholomae CC, Vicenzi E, Finocchi A, Bredius R, Bosticardo M, Schmidt M, von Kalle C, Montini E, Biffi A, Roncarolo MG, Naldini L, Villa A, Aiuti A.

Mol Ther. 2013 Jan;21(1):175-84. doi: 10.1038/mt.2012.23. Epub 2012 Feb 28. Erratum in: Mol Ther. 2016 Jun;24(6):1159.

29.

Enzymatic mono-pegylation of glucagon-like peptide 1 towards long lasting treatment of type 2 diabetes.

Selis F, Schrepfer R, Sanna R, Scaramuzza S, Tonon G, Dedoni S, Onali P, Orsini G, Genovese S.

Results Pharma Sci. 2012 Sep 18;2:58-65. doi: 10.1016/j.rinphs.2012.09.001. eCollection 2012.

30.

Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID.

Sauer AV, Brigida I, Carriglio N, Hernandez RJ, Scaramuzza S, Clavenna D, Sanvito F, Poliani PL, Gagliani N, Carlucci F, Tabucchi A, Roncarolo MG, Traggiai E, Villa A, Aiuti A.

Blood. 2012 Feb 9;119(6):1428-39. doi: 10.1182/blood-2011-07-366781. Epub 2011 Dec 19.

31.

Early-onset monocyte-B-natural killer-dendritic cells' deficiency successfully treated with hematopoietic stem cell transplantation.

Cancrini C, Scarselli A, Scaramuzza S, Chiriaco M, Di Cesare S, Di Matteo G, Romiti ML, Palma P, De Felice L, Palumbo G, Pinto RM, De Vito R, Racioppi L, Livadiotti S, Fischer A, Rossi P, Caniglia M, Aiuti A.

J Allergy Clin Immunol. 2011 Oct;128(4):897-900.e1. doi: 10.1016/j.jaci.2011.07.044. Epub 2011 Aug 25. No abstract available.

PMID:
21868074
32.

In vivo T-cell dynamics during immune reconstitution after hematopoietic stem cell gene therapy in adenosine deaminase severe combined immune deficiency.

Selleri S, Brigida I, Casiraghi M, Scaramuzza S, Cappelli B, Cassani B, Ferrua F, Aker M, Slavin S, Scarselli A, Cancrini C, Marktel S, Grazia Roncarolo M, Aiuti A.

J Allergy Clin Immunol. 2011 Jun;127(6):1368-75.e8. doi: 10.1016/j.jaci.2011.03.004. Epub 2011 Apr 7.

PMID:
21477850
33.

Revertant T lymphocytes in a patient with Wiskott-Aldrich syndrome: analysis of function and distribution in lymphoid organs.

Trifari S, Scaramuzza S, Catucci M, Ponzoni M, Mollica L, Chiesa R, Cattaneo F, Lafouresse F, Calvez R, Vermi W, Medicina D, Castiello MC, Marangoni F, Bosticardo M, Doglioni C, Caniglia M, Aiuti A, Villa A, Roncarolo MG, Dupré L.

J Allergy Clin Immunol. 2010 Feb;125(2):439-448.e8. doi: 10.1016/j.jaci.2009.11.034.

PMID:
20159256
34.

Corrigendum to "Evidence for Long-term Efficacy and Safety of Gene Therapy for Wiskott-Aldrich Syndrome in Preclinical Models".

Marangoni F, Bosticardo M, Charrier S, Draghici E, Locci M, Scaramuzza S, Panaroni C, Ponzoni M, Sanvito F, Doglioni C, Liabeuf M, Gjata B, Montus M, Siminovitch K, Aiuti A, Naldini L, Dupré L, Roncarolo MG, Galy A, Villa A.

Mol Ther. 2009 Jul;17(7):1300. doi: 10.1038/mt.2009.61. Epub 2016 Dec 6. No abstract available.

35.

Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models.

Marangoni F, Bosticardo M, Charrier S, Draghici E, Locci M, Scaramuzza S, Panaroni C, Ponzoni M, Sanvito F, Doglioni C, Liabeuf M, Gjata B, Montus M, Siminovitch K, Aiuti A, Naldini L, Dupré L, Roncarolo MG, Galy A, Villa A.

Mol Ther. 2009 Jun;17(6):1073-82. doi: 10.1038/mt.2009.31. Epub 2009 Mar 3. Erratum in: Mol Ther. 2009 Jul;17(7):1300.

36.

Gene therapy for immunodeficiency due to adenosine deaminase deficiency.

Aiuti A, Cattaneo F, Galimberti S, Benninghoff U, Cassani B, Callegaro L, Scaramuzza S, Andolfi G, Mirolo M, Brigida I, Tabucchi A, Carlucci F, Eibl M, Aker M, Slavin S, Al-Mousa H, Al Ghonaium A, Ferster A, Duppenthaler A, Notarangelo L, Wintergerst U, Buckley RH, Bregni M, Marktel S, Valsecchi MG, Rossi P, Ciceri F, Miniero R, Bordignon C, Roncarolo MG.

N Engl J Med. 2009 Jan 29;360(5):447-58. doi: 10.1056/NEJMoa0805817.

37.

TNK cells (NKG2D+ CD8+ or CD4+ T lymphocytes) in the control of human tumors.

Maccalli C, Scaramuzza S, Parmiani G.

Cancer Immunol Immunother. 2009 May;58(5):801-8. doi: 10.1007/s00262-008-0635-x. Epub 2008 Dec 17. Review.

PMID:
19089424
38.

A new PEG-beta-alanine active derivative for releasable protein conjugation.

Pasut G, Mero A, Caboi F, Scaramuzza S, Sollai L, Veronese FM.

Bioconjug Chem. 2008 Dec;19(12):2427-31. doi: 10.1021/bc800281s.

PMID:
19053302
39.

Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy.

Aiuti A, Cassani B, Andolfi G, Mirolo M, Biasco L, Recchia A, Urbinati F, Valacca C, Scaramuzza S, Aker M, Slavin S, Cazzola M, Sartori D, Ambrosi A, Di Serio C, Roncarolo MG, Mavilio F, Bordignon C.

J Clin Invest. 2007 Aug;117(8):2233-40.

40.

Molecular purging of multiple myeloma cells by ex-vivo culture and retroviral transduction of mobilized-blood CD34+ cells.

Deola S, Scaramuzza S, Birolo RS, Cergnul M, Ficara F, Dando J, Voena C, Vai S, Monari M, Pogliani E, Corneo G, Peccatori J, Selleri S, Bordignon C, Roncarolo MG, Aiuti A, Bregni M.

J Transl Med. 2007 Jul 12;5:35.

41.

Current understanding of the Wiskott-Aldrich syndrome and prospects for gene therapy.

Trifari S, Marangoni F, Scaramuzza S, Aiuti A, Roncarolo MG, Dupré L.

Expert Rev Clin Immunol. 2007 Mar;3(2):205-15. doi: 10.1586/1744666X.3.2.205.

PMID:
20477109
42.

WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells.

Marangoni F, Trifari S, Scaramuzza S, Panaroni C, Martino S, Notarangelo LD, Baz Z, Metin A, Cattaneo F, Villa A, Aiuti A, Battaglia M, Roncarolo MG, Dupré L.

J Exp Med. 2007 Feb 19;204(2):369-80. Epub 2007 Feb 12.

43.

Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich syndrome patients.

Trifari S, Sitia G, Aiuti A, Scaramuzza S, Marangoni F, Guidotti LG, Martino S, Saracco P, Notarangelo LD, Roncarolo MG, Dupré L.

J Immunol. 2006 Nov 15;177(10):7451-61.

44.

Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients.

Charrier S, Dupré L, Scaramuzza S, Jeanson-Leh L, Blundell MP, Danos O, Cattaneo F, Aiuti A, Eckenberg R, Thrasher AJ, Roncarolo MG, Galy A.

Gene Ther. 2007 Mar;14(5):415-28. Epub 2006 Oct 19.

PMID:
17051251
45.

Efficacy of gene therapy for Wiskott-Aldrich syndrome using a WAS promoter/cDNA-containing lentiviral vector and nonlethal irradiation.

Dupré L, Marangoni F, Scaramuzza S, Trifari S, Hernández RJ, Aiuti A, Naldini L, Roncarolo MG.

Hum Gene Ther. 2006 Mar;17(3):303-13.

PMID:
16544979
46.

Bone marrow mammaglobin expression as a marker of graft-versus-tumor effect after reduced-intensity allografting for advanced breast cancer.

Bregni M, Fleischhauer K, Bernardi M, Pescarollo A, Guggiari E, Lunghi F, Deola S, Scaramuzza S, Re F, Setola E, Monari M, Mazzi B, Servida P, Corradini P, Peccatori J.

Bone Marrow Transplant. 2006 Feb;37(3):311-5.

PMID:
16400340
47.

Mobilized blood CD34+ cells transduced and selected with a clinically applicable protocol reconstitute lymphopoiesis in SCID-Hu mice.

Deola S, Scaramuzza S, Birolo RS, Carballido-Perrig N, Ficara F, Mocchetti C, Dando J, Carballido JM, Bordignon C, Roncarolo MG, Bregni M, Aiuti A.

Hum Gene Ther. 2004 Mar;15(3):305-11.

PMID:
15018739

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