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Items: 31


Innate inflammation and synovial macrophages in osteoarthritis pathophysiology.

Griffin TM, Scanzello CR.

Clin Exp Rheumatol. 2019 Sep-Oct;37 Suppl 120(5):57-63. Epub 2019 Oct 15. Review.


An emerging role for Toll-like receptors at the neuroimmune interface in osteoarthritis.

Miller RE, Scanzello CR, Malfait AM.

Semin Immunopathol. 2019 Sep;41(5):583-594. doi: 10.1007/s00281-019-00762-3. Epub 2019 Oct 14. Review.


Deficiency of the pattern-recognition receptor CD14 protects against joint pathology and functional decline in a murine model of osteoarthritis.

Sambamurthy N, Zhou C, Nguyen V, Smalley R, Hankenson KD, Dodge GR, Scanzello CR.

PLoS One. 2018 Nov 28;13(11):e0206217. doi: 10.1371/journal.pone.0206217. eCollection 2018.


Chemokine receptor-7 (CCR7) deficiency leads to delayed development of joint damage and functional deficits in a murine model of osteoarthritis.

Sambamurthy N, Nguyen V, Smalley R, Xiao R, Hankenson K, Gan J, Miller RE, Malfait AM, Dodge GR, Scanzello CR.

J Orthop Res. 2018 Mar;36(3):864-875. doi: 10.1002/jor.23671. Epub 2017 Aug 29.


Chemokines and inflammation in osteoarthritis: Insights from patients and animal models.

Scanzello CR.

J Orthop Res. 2017 Apr;35(4):735-739. doi: 10.1002/jor.23471. Epub 2017 Mar 8. Review.


Role of low-grade inflammation in osteoarthritis.

Scanzello CR.

Curr Opin Rheumatol. 2017 Jan;29(1):79-85. Review.


Inflammation in joint injury and post-traumatic osteoarthritis.

Lieberthal J, Sambamurthy N, Scanzello CR.

Osteoarthritis Cartilage. 2015 Nov;23(11):1825-34. doi: 10.1016/j.joca.2015.08.015. Review.


Editorial: inflammatory activity in symptomatic knee osteoarthritis: not all inflammation is local.

Scanzello CR, Loeser RF.

Arthritis Rheumatol. 2015 Nov;67(11):2797-800. doi: 10.1002/art.39304. No abstract available.


Synovial chemokine expression and relationship with knee symptoms in patients with meniscal tears.

Nair A, Gan J, Bush-Joseph C, Verma N, Tetreault MW, Saha K, Margulis A, Fogg L, Scanzello CR.

Osteoarthritis Cartilage. 2015 Jul;23(7):1158-64. doi: 10.1016/j.joca.2015.02.016. Epub 2015 Feb 24.


Fibronectin splice variation in human knee cartilage, meniscus and synovial membrane: observations in osteoarthritic knee.

Scanzello CR, Markova DZ, Chee A, Xiu Y, Adams SL, Anderson G, Zgonis M, Qin L, An HS, Zhang Y.

J Orthop Res. 2015 Apr;33(4):556-62. doi: 10.1002/jor.22787. Epub 2015 Jan 6.


Identification of myeloid-derived suppressor cells in the synovial fluid of patients with rheumatoid arthritis: a pilot study.

Kurkó J, Vida A, Glant TT, Scanzello CR, Katz RS, Nair A, Szekanecz Z, Mikecz K.

BMC Musculoskelet Disord. 2014 Aug 19;15:281. doi: 10.1186/1471-2474-15-281.


The influence of synovial inflammation and hyperplasia on symptomatic outcomes up to 2 years post-operatively in patients undergoing partial meniscectomy.

Scanzello CR, Albert AS, DiCarlo E, Rajan KB, Kanda V, Asomugha EU, Swaim BH, Katz JN, Goldring SR, Richmond JC, McKeon B.

Osteoarthritis Cartilage. 2013 Sep;21(9):1392-9. doi: 10.1016/j.joca.2013.05.011.


Proteomic analysis of synovial fluid from the osteoarthritic knee: comparison with transcriptome analyses of joint tissues.

Ritter SY, Subbaiah R, Bebek G, Crish J, Scanzello CR, Krastins B, Sarracino D, Lopez MF, Crow MK, Aigner T, Goldring MB, Goldring SR, Lee DM, Gobezie R, Aliprantis AO.

Arthritis Rheum. 2013 Apr;65(4):981-92. doi: 10.1002/art.37823.


Pathologic and pathogenic processes in osteoarthritis: the effects of synovitis.

Scanzello CR.

HSS J. 2012 Feb;8(1):20-2. doi: 10.1007/s11420-011-9228-x. Epub 2011 Dec 23. No abstract available.


Synovial fluid from patients with early osteoarthritis modulates fibroblast-like synoviocyte responses to toll-like receptor 4 and toll-like receptor 2 ligands via soluble CD14.

Nair A, Kanda V, Bush-Joseph C, Verma N, Chubinskaya S, Mikecz K, Glant TT, Malfait AM, Crow MK, Spear GT, Finnegan A, Scanzello CR.

Arthritis Rheum. 2012 Jul;64(7):2268-77. doi: 10.1002/art.34495.


Osteoarthritis: a disease of the joint as an organ.

Loeser RF, Goldring SR, Scanzello CR, Goldring MB.

Arthritis Rheum. 2012 Jun;64(6):1697-707. doi: 10.1002/art.34453. Epub 2012 Mar 5. Review. No abstract available.


The role of synovitis in osteoarthritis pathogenesis.

Scanzello CR, Goldring SR.

Bone. 2012 Aug;51(2):249-57. doi: 10.1016/j.bone.2012.02.012. Epub 2012 Feb 22. Review.


Plasma proteins take their toll on the joint in osteoarthritis.

Goldring SR, Scanzello CR.

Arthritis Res Ther. 2012 Mar 5;14(2):111. doi: 10.1186/ar3741. No abstract available.


Identification of a central role for complement in osteoarthritis.

Wang Q, Rozelle AL, Lepus CM, Scanzello CR, Song JJ, Larsen DM, Crish JF, Bebek G, Ritter SY, Lindstrom TM, Hwang I, Wong HH, Punzi L, Encarnacion A, Shamloo M, Goodman SB, Wyss-Coray T, Goldring SR, Banda NK, Thurman JM, Gobezie R, Crow MK, Holers VM, Lee DM, Robinson WH.

Nat Med. 2011 Nov 6;17(12):1674-9. doi: 10.1038/nm.2543.


Non-surgical treatment of osteoarthritis-related pain in the elderly.

Mushtaq S, Choudhary R, Scanzello CR.

Curr Rev Musculoskelet Med. 2011 Sep;4(3):113-22. doi: 10.1007/s12178-011-9084-9.


Synovial inflammation in patients undergoing arthroscopic meniscectomy: molecular characterization and relationship to symptoms.

Scanzello CR, McKeon B, Swaim BH, DiCarlo E, Asomugha EU, Kanda V, Nair A, Lee DM, Richmond JC, Katz JN, Crow MK, Goldring SR.

Arthritis Rheum. 2011 Feb;63(2):391-400. doi: 10.1002/art.30137.


Perioperative management of biologic agents used in treatment of rheumatoid arthritis.

Mushtaq S, Goodman SM, Scanzello CR.

Am J Ther. 2011 Sep;18(5):426-34. doi: 10.1097/MJT.0b013e3181cb4042. Review.


Local cytokine profiles in knee osteoarthritis: elevated synovial fluid interleukin-15 differentiates early from end-stage disease.

Scanzello CR, Umoh E, Pessler F, Diaz-Torne C, Miles T, Dicarlo E, Potter HG, Mandl L, Marx R, Rodeo S, Goldring SR, Crow MK.

Osteoarthritis Cartilage. 2009 Aug;17(8):1040-8. doi: 10.1016/j.joca.2009.02.011. Epub 2009 Mar 6.


Perioperative management of medications used in the treatment of rheumatoid arthritis.

Scanzello CR, Figgie MP, Nestor BJ, Goodman SM.

HSS J. 2006 Sep;2(2):141-7. doi: 10.1007/s11420-006-9012-5.


Innate immune system activation in osteoarthritis: is osteoarthritis a chronic wound?

Scanzello CR, Plaas A, Crow MK.

Curr Opin Rheumatol. 2008 Sep;20(5):565-72. doi: 10.1097/BOR.0b013e32830aba34. Review.


The post-NSAID era: what to use now for the pharmacologic treatment of pain and inflammation in osteoarthritis.

Scanzello CR, Moskowitz NK, Gibofsky A.

Curr Rheumatol Rep. 2008 Jan;10(1):49-56. Review.


The post-NSAID era: what to use now for the pharmacologic treatment of pain and inflammation in osteoarthritis.

Scanzello CR, Moskowitz NK, Gibofsky A.

Curr Pain Headache Rep. 2007 Dec;11(6):415-22. Review.


Elevated high-sensitivity C-reactive protein levels are associated with local inflammatory findings in patients with osteoarthritis.

Pearle AD, Scanzello CR, George S, Mandl LA, DiCarlo EF, Peterson M, Sculco TP, Crow MK.

Osteoarthritis Cartilage. 2007 May;15(5):516-23. Epub 2006 Dec 5.


Rituximab treatment of thrombotic thrombocytopenic purpura in the setting of connective tissue disease.

Niewold TB, Alpert D, Scanzello CR, Paget SA.

J Rheumatol. 2006 Jun;33(6):1194-6.


Interleukin-12 is expressed by infiltrating macrophages and synovial lining cells in rheumatoid arthritis and osteoarthritis.

Sakkas LI, Johanson NA, Scanzello CR, Platsoucas CD.

Cell Immunol. 1998 Sep 15;188(2):105-10.


Serotonergic recovery after (+/-)3,4-(methylenedioxy) methamphetamine injury: observations in rats.

Scanzello CR, Hatzidimitriou G, Martello AL, Katz JL, Ricaurte GA.

J Pharmacol Exp Ther. 1993 Mar;264(3):1484-91.


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