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Items: 1 to 50 of 175

1.

Design of a Fragment-Screening Library.

Taylor A, Doak BC, Scanlon MJ.

Methods Enzymol. 2018;610:97-115. doi: 10.1016/bs.mie.2018.09.018. Epub 2018 Oct 19.

PMID:
30390807
2.

Transcriptomic and functional analysis of cucumber (Cucumis sativus L.) fruit phloem during early development.

Sui X, Nie J, Li X, Scanlon MJ, Zhang C, Zheng Y, Ma S, Shan N, Fei Z, Turgeon R, Zhang Z.

Plant J. 2018 Sep 8. doi: 10.1111/tpj.14084. [Epub ahead of print]

PMID:
30194881
3.

Bulked-Segregant Analysis Coupled to Whole Genome Sequencing (BSA-Seq) for Rapid Gene Cloning in Maize.

Klein H, Xiao Y, Conklin PA, Govindarajulu R, Kelly JA, Scanlon MJ, Whipple CJ, Bartlett M.

G3 (Bethesda). 2018 Nov 6;8(11):3583-3592. doi: 10.1534/g3.118.200499.

4.

Intragenic Meiotic Crossovers Generate Novel Alleles with Transgressive Expression Levels.

Liu S, Schnable JC, Ott A, Yeh CE, Springer NM, Yu J, Muehlbauer G, Timmermans MCP, Scanlon MJ, Schnable PS.

Mol Biol Evol. 2018 Nov 1;35(11):2762-2772. doi: 10.1093/molbev/msy174.

PMID:
30184112
5.

Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens.

Smith RP, Mohanty B, Mowlaboccus S, Paxman JJ, Williams ML, Headey SJ, Wang G, Subedi P, Doak BC, Kahler CM, Scanlon MJ, Heras B.

J Biol Chem. 2018 Oct 26;293(43):16559-16571. doi: 10.1074/jbc.RA118.004847. Epub 2018 Sep 4.

PMID:
30181210
6.

Correction to: Genome-wide discovery and characterization of maize long non-coding RNAs.

Li L, Eichten SR, Shimizu R, Petsch K, Yeh CT, Wu W, Chettoor AM, Givan SA, Cole RA, Fowler JE, Evans MMS, Scanlon MJ, Yu J, Schnable PS, Timmermans MCP, Springer NM, Muehlbauer GJ.

Genome Biol. 2018 Aug 23;19(1):122. doi: 10.1186/s13059-018-1508-z.

7.

On the mechanisms of development in monocot and eudicot leaves.

Conklin PA, Strable J, Li S, Scanlon MJ.

New Phytol. 2018 Aug 14. doi: 10.1111/nph.15371. [Epub ahead of print] Review.

PMID:
30106472
8.

CLAVATA Was a Genetic Novelty for the Morphological Innovation of 3D Growth in Land Plants.

Whitewoods CD, Cammarata J, Nemec Venza Z, Sang S, Crook AD, Aoyama T, Wang XY, Waller M, Kamisugi Y, Cuming AC, Szövényi P, Nimchuk ZL, Roeder AHK, Scanlon MJ, Harrison CJ.

Curr Biol. 2018 Aug 6;28(15):2365-2376.e5. doi: 10.1016/j.cub.2018.05.068. Epub 2018 Jul 19.

9.

Cyclic Hexapeptide Mimics of the LEDGF Integrase Recognition Loop in Complex with HIV-1 Integrase.

Northfield SE, Wielens J, Headey SJ, Williams-Noonan BJ, Mulcair M, Scanlon MJ, Parker MW, Thompson PE, Chalmers DK.

ChemMedChem. 2018 Aug 10;13(15):1555-1565. doi: 10.1002/cmdc.201800129. Epub 2018 Jul 6.

PMID:
29862651
10.

Dietary docosahexaenoic acid supplementation enhances expression of fatty acid-binding protein 5 at the blood-brain barrier and brain docosahexaenoic acid levels.

Pan Y, Morris ER, Scanlon MJ, Marriott PJ, Porter CJH, Nicolazzo JA.

J Neurochem. 2018 Jul;146(2):186-197. doi: 10.1111/jnc.14342.

PMID:
29582413
11.

Fragment-Based Discovery of Inhibitors of the Bacterial DnaG-SSB Interaction.

Chilingaryan Z, Headey SJ, Lo ATY, Xu ZQ, Otting G, Dixon NE, Scanlon MJ, Oakley AJ.

Antibiotics (Basel). 2018 Feb 22;7(1). pii: E14. doi: 10.3390/antibiotics7010014.

12.

Correction: Mendelian and Non-Mendelian Regulation of Gene Expression in Maize.

Li L, Petsch K, Shimizu R, Liu S, Xu WW, Ying K, Yu J, Scanlon MJ, Schnable PS, Timmermans MCP, Springer NM, Muehlbauer GJ.

PLoS Genet. 2018 Feb 14;14(2):e1007234. doi: 10.1371/journal.pgen.1007234. eCollection 2018 Feb.

13.

Production, biophysical characterization and initial crystallization studies of the N- and C-terminal domains of DsbD, an essential enzyme in Neisseria meningitidis.

Smith RP, Whitten AE, Paxman JJ, Kahler CM, Scanlon MJ, Heras B.

Acta Crystallogr F Struct Biol Commun. 2018 Jan 1;74(Pt 1):31-38. doi: 10.1107/S2053230X17017800. Epub 2018 Jan 1.

PMID:
29372905
14.

Fatty Acid-Binding Protein 5 Mediates the Uptake of Fatty Acids, but not Drugs, Into Human Brain Endothelial Cells.

Lee GS, Pan Y, Scanlon MJ, Porter CJH, Nicolazzo JA.

J Pharm Sci. 2018 Apr;107(4):1185-1193. doi: 10.1016/j.xphs.2017.11.024. Epub 2017 Dec 14.

PMID:
29247738
15.

Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens.

Totsika M, Vagenas D, Paxman JJ, Wang G, Dhouib R, Sharma P, Martin JL, Scanlon MJ, Heras B.

Antioxid Redox Signal. 2018 Sep 1;29(7):653-666. doi: 10.1089/ars.2017.7104. Epub 2018 Feb 1.

16.

Reduced blood-brain barrier expression of fatty acid-binding protein 5 is associated with increased vulnerability of APP/PS1 mice to cognitive deficits from low omega-3 fatty acid diets.

Pan Y, Choy KHC, Marriott PJ, Chai SY, Scanlon MJ, Porter CJH, Short JL, Nicolazzo JA.

J Neurochem. 2018 Jan;144(1):81-92. doi: 10.1111/jnc.14249.

PMID:
29105065
17.

Substantial contribution of genetic variation in the expression of transcription factors to phenotypic variation revealed by eRD-GWAS.

Lin HY, Liu Q, Li X, Yang J, Liu S, Huang Y, Scanlon MJ, Nettleton D, Schnable PS.

Genome Biol. 2017 Oct 17;18(1):192. doi: 10.1186/s13059-017-1328-6.

18.

The first total synthesis and solution structure of a polypeptin, PE2, a cyclic lipopeptide with broad spectrum antibiotic activity.

Mountford SJ, Mohanty B, Roberts KD, Yu HH, Scanlon MJ, Nation RL, Velkov T, Li J, Thompson PE.

Org Biomol Chem. 2017 Aug 30;15(34):7173-7180. doi: 10.1039/c7ob01493g.

PMID:
28812779
19.

Dissecting Tissue-Specific Transcriptomic Responses from Leaf and Roots under Salt Stress in Petunia hybrida Mitchell.

Villarino GH, Hu Q, Scanlon MJ, Mueller L, Bombarely A, Mattson NS.

Genes (Basel). 2017 Aug 3;8(8). pii: E195. doi: 10.3390/genes8080195.

20.

HN, N, Cα and Cβ assignments of the two periplasmic domains of Neisseria meningitidis DsbD.

Smith RP, Mohanty B, Williams ML, Scanlon MJ, Heras B.

Biomol NMR Assign. 2017 Oct;11(2):181-186. doi: 10.1007/s12104-017-9743-x. Epub 2017 Jun 6.

PMID:
28589218
21.

Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief.

Jensen DD, Lieu T, Halls ML, Veldhuis NA, Imlach WL, Mai QN, Poole DP, Quach T, Aurelio L, Conner J, Herenbrink CK, Barlow N, Simpson JS, Scanlon MJ, Graham B, McCluskey A, Robinson PJ, Escriou V, Nassini R, Materazzi S, Geppetti P, Hicks GA, Christie MJ, Porter CJH, Canals M, Bunnett NW.

Sci Transl Med. 2017 May 31;9(392). pii: eaal3447. doi: 10.1126/scitranslmed.aal3447.

22.

Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1.

Mohanty B, Rimmer K, McMahon RM, Headey SJ, Vazirani M, Shouldice SR, Coinçon M, Tay S, Morton CJ, Simpson JS, Martin JL, Scanlon MJ.

PLoS One. 2017 Mar 27;12(3):e0173436. doi: 10.1371/journal.pone.0173436. eCollection 2017.

23.

Experimental Design for Laser Microdissection RNA-Seq: Lessons from an Analysis of Maize Leaf Development.

Johnston RM, Sylvester AW, Scanlon MJ.

J Vis Exp. 2017 Mar 5;(121). doi: 10.3791/55004.

PMID:
28287567
24.

Modeling the Morphometric Evolution of the Maize Shoot Apical Meristem.

Leiboff S, DeAllie CK, Scanlon MJ.

Front Plant Sci. 2016 Nov 4;7:1651. eCollection 2016.

25.

Fatty Acid-Binding Protein 5 at the Blood-Brain Barrier Regulates Endogenous Brain Docosahexaenoic Acid Levels and Cognitive Function.

Pan Y, Short JL, Choy KH, Zeng AX, Marriott PJ, Owada Y, Scanlon MJ, Porter CJ, Nicolazzo JA.

J Neurosci. 2016 Nov 16;36(46):11755-11767.

26.

Determination of ligand binding modes in weak protein-ligand complexes using sparse NMR data.

Mohanty B, Williams ML, Doak BC, Vazirani M, Ilyichova O, Wang G, Bermel W, Simpson JS, Chalmers DK, King GF, Mobli M, Scanlon MJ.

J Biomol NMR. 2016 Nov;66(3):195-208. Epub 2016 Oct 24.

PMID:
27778134
27.

The ways and means of fragment-based drug design.

Doak BC, Norton RS, Scanlon MJ.

Pharmacol Ther. 2016 Nov;167:28-37. doi: 10.1016/j.pharmthera.2016.07.003. Epub 2016 Jul 22. Review.

PMID:
27452339
28.

Targeting Bacterial Dsb Proteins for the Development of Anti-Virulence Agents.

Smith RP, Paxman JJ, Scanlon MJ, Heras B.

Molecules. 2016 Jul 16;21(7). pii: E811. doi: 10.3390/molecules21070811. Review.

29.

Structure-Activity Studies of β-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.

Wang G, Drinkwater N, Drew DR, MacRaild CA, Chalmers DK, Mohanty B, Lim SS, Anders RF, Beeson JG, Thompson PE, McGowan S, Simpson JS, Norton RS, Scanlon MJ.

J Mol Biol. 2016 Oct 9;428(20):3986-3998. doi: 10.1016/j.jmb.2016.07.001. Epub 2016 Jul 14.

PMID:
27422009
30.

Meristems take their cues from organ primordia.

Strable J, Scanlon MJ.

Nat Genet. 2016 Jun 28;48(7):704-5. doi: 10.1038/ng.3601.

PMID:
27350600
31.

Design, Synthesis, and Characterization of Cyclic Peptidomimetics of the Inducible Nitric Oxide Synthase Binding Epitope That Disrupt the Protein-Protein Interaction Involving SPRY Domain-Containing Suppressor of Cytokine Signaling Box Protein (SPSB) 2 and Inducible Nitric Oxide Synthase.

Harjani JR, Yap BK, Leung EW, Lucke A, Nicholson SE, Scanlon MJ, Chalmers DK, Thompson PE, Norton RS, Baell JB.

J Med Chem. 2016 Jun 23;59(12):5799-809. doi: 10.1021/acs.jmedchem.6b00386. Epub 2016 Jun 8.

PMID:
27214043
32.

Binding of CFA/I Pili of Enterotoxigenic Escherichia coli to Asialo-GM1 Is Mediated by the Minor Pilin CfaE.

Madhavan TPV, Riches JD, Scanlon MJ, Ulett GC, Sakellaris H.

Infect Immun. 2016 Apr 22;84(5):1642-1649. doi: 10.1128/IAI.01562-15. Print 2016 May.

33.

Redox-stable cyclic peptide inhibitors of the SPSB2-iNOS interaction.

Yap BK, Harjani JR, Leung EW, Nicholson SE, Scanlon MJ, Chalmers DK, Thompson PE, Baell JB, Norton RS.

FEBS Lett. 2016 Mar;590(6):696-704. doi: 10.1002/1873-3468.12115. Epub 2016 Mar 6.

34.

Solution NMR characterization of apical membrane antigen 1 and small molecule interactions as a basis for designing new antimalarials.

Krishnarjuna B, Lim SS, Devine SM, Debono CO, Lam R, Chandrashekaran IR, Jaipuria G, Yagi H, Atreya HS, Scanlon MJ, MacRaild CA, Scammells PJ, Norton RS.

J Mol Recognit. 2016 Jun;29(6):281-91. doi: 10.1002/jmr.2529. Epub 2016 Jan 24.

PMID:
26804042
35.

Fractionation and subfunctionalization following genome duplications: mechanisms that drive gene content and their consequences.

Freeling M, Scanlon MJ, Fowler JE.

Curr Opin Genet Dev. 2015 Dec;35:110-8. doi: 10.1016/j.gde.2015.11.002. Epub 2015 Dec 4. Review.

PMID:
26657818
36.

Sent packing: protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility.

McMahon RM, Coinçon M, Tay S, Heras B, Morton CJ, Scanlon MJ, Martin JL.

Acta Crystallogr D Biol Crystallogr. 2015 Dec 1;71(Pt 12):2386-95. doi: 10.1107/S1399004715018519. Epub 2015 Nov 26.

37.

Genetic control of morphometric diversity in the maize shoot apical meristem.

Leiboff S, Li X, Hu HC, Todt N, Yang J, Li X, Yu X, Muehlbauer GJ, Timmermans MC, Yu J, Schnable PS, Scanlon MJ.

Nat Commun. 2015 Nov 20;6:8974. doi: 10.1038/ncomms9974.

38.

Fatty Acid-Binding Protein 5 Facilitates the Blood-Brain Barrier Transport of Docosahexaenoic Acid.

Pan Y, Scanlon MJ, Owada Y, Yamamoto Y, Porter CJ, Nicolazzo JA.

Mol Pharm. 2015 Dec 7;12(12):4375-85. doi: 10.1021/acs.molpharmaceut.5b00580. Epub 2015 Oct 30.

39.

Laser Microdissection-Mediated Isolation and In Vitro Transcriptional Amplification of Plant RNA.

Chandran D, Scanlon MJ, Ohtsu K, Timmermans MC, Schnable PS, Wildermuth MC.

Curr Protoc Mol Biol. 2015 Oct 1;112:25A.3.1-23. doi: 10.1002/0471142727.mb25a03s112.

PMID:
26423587
40.

Transcriptomic Evidence for the Evolution of Shoot Meristem Function in Sporophyte-Dominant Land Plants through Concerted Selection of Ancestral Gametophytic and Sporophytic Genetic Programs.

Frank MH, Scanlon MJ.

Mol Biol Evol. 2015 Nov;32(11):3033. doi: 10.1093/molbev/msv182. Epub 2015 Sep 28. No abstract available.

PMID:
26416978
41.

Protein unfolding is essential for cleavage within the α-helix of a model protein substrate by the serine protease, thrombin.

Robertson AL, Headey SJ, Ng NM, Wijeyewickrema LC, Scanlon MJ, Pike RN, Bottomley SP.

Biochimie. 2016 Mar;122:227-34. doi: 10.1016/j.biochi.2015.09.021. Epub 2015 Sep 25.

PMID:
26403495
42.

Leaves of grass: focusing phenomics on maize leaf growth.

Scanlon MJ.

Genome Biol. 2015 Sep 17;16:196. doi: 10.1186/s13059-015-0773-3.

43.

Fatty Acid Binding Proteins Expressed at the Human Blood-Brain Barrier Bind Drugs in an Isoform-Specific Manner.

Lee GS, Kappler K, Porter CJ, Scanlon MJ, Nicolazzo JA.

Pharm Res. 2015 Oct;32(10):3432-46. doi: 10.1007/s11095-015-1764-5. Epub 2015 Aug 7.

PMID:
26248795
44.

Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module.

Selkrig J, Belousoff MJ, Headey SJ, Heinz E, Shiota T, Shen HH, Beckham SA, Bamert RS, Phan MD, Schembri MA, Wilce MC, Scanlon MJ, Strugnell RA, Lithgow T.

Sci Rep. 2015 Aug 5;5:12905. doi: 10.1038/srep12905.

45.

Cell-specific transcriptomic analyses of three-dimensional shoot development in the moss Physcomitrella patens.

Frank MH, Scanlon MJ.

Plant J. 2015 Aug;83(4):743-51. doi: 10.1111/tpj.12928. Epub 2015 Jul 22.

46.

Dissecting the molecular signatures of apical cell-type shoot meristems from two ancient land plant lineages.

Frank MH, Edwards MB, Schultz ER, McKain MR, Fei Z, Sørensen I, Rose JK, Scanlon MJ.

New Phytol. 2015 Aug;207(3):893-904. doi: 10.1111/nph.13407. Epub 2015 Apr 21.

47.

Fatty Acid-binding Proteins 1 and 2 Differentially Modulate the Activation of Peroxisome Proliferator-activated Receptor α in a Ligand-selective Manner.

Hughes ML, Liu B, Halls ML, Wagstaff KM, Patil R, Velkov T, Jans DA, Bunnett NW, Scanlon MJ, Porter CJ.

J Biol Chem. 2015 May 29;290(22):13895-906. doi: 10.1074/jbc.M114.605998. Epub 2015 Apr 6.

48.

The barley Uniculme4 gene encodes a BLADE-ON-PETIOLE-like protein that controls tillering and leaf patterning.

Tavakol E, Okagaki R, Verderio G, Shariati J V, Hussien A, Bilgic H, Scanlon MJ, Todt NR, Close TJ, Druka A, Waugh R, Steuernagel B, Ariyadasa R, Himmelbach A, Stein N, Muehlbauer GJ, Rossini L.

Plant Physiol. 2015 May;168(1):164-74. doi: 10.1104/pp.114.252882. Epub 2015 Mar 27.

49.

Evolutionary patterns of DNA base composition and correlation to polymorphisms in DNA repair systems.

Li X, Scanlon MJ, Yu J.

Nucleic Acids Res. 2015 Apr 20;43(7):3614-25. doi: 10.1093/nar/gkv197. Epub 2015 Mar 12.

50.

Diversity of maize shoot apical meristem architecture and its relationship to plant morphology.

Thompson AM, Yu J, Timmermans MC, Schnable P, Crants JC, Scanlon MJ, Muehlbauer GJ.

G3 (Bethesda). 2015 Mar 5;5(5):819-27. doi: 10.1534/g3.115.017541.

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