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Items: 47


Identification of human tumor antigens by serological analysis of recombinant cDNA expression libraries (SEREX).

Scanlan MJ.

Curr Protoc Immunol. 2005 Mar;Chapter 20:Unit 20.7. doi: 10.1002/0471142735.im2007s65.


Frequent and specific immunity to the embryonal stem cell-associated antigen SOX2 in patients with monoclonal gammopathy.

Spisek R, Kukreja A, Chen LC, Matthews P, Mazumder A, Vesole D, Jagannath S, Zebroski HA, Simpson AJ, Ritter G, Durie B, Crowley J, Shaughnessy JD Jr, Scanlan MJ, Gure AO, Barlogie B, Dhodapkar MV.

J Exp Med. 2007 Apr 16;204(4):831-40. Epub 2007 Mar 26.


Glycoprotein A34, a novel target for antibody-based cancer immunotherapy.

Scanlan MJ, Ritter G, Yin BW, Williams C Jr, Cohen LS, Coplan KA, Fortunato SR, Frosina D, Lee SY, Murray AE, Chua R, Filonenko VV, Sato E, Old LJ, Jungbluth AA.

Cancer Immun. 2006 Jan 12;6:2.


A-kinase anchoring protein 3 messenger RNA expression correlates with poor prognosis in epithelial ovarian cancer.

Sharma S, Qian F, Keitz B, Driscoll D, Scanlan MJ, Skipper J, Rodabaugh K, Lele S, Old LJ, Odunsi K.

Gynecol Oncol. 2005 Oct;99(1):183-8.


Identification of cancer/testis-antigen genes by massively parallel signature sequencing.

Chen YT, Scanlan MJ, Venditti CA, Chua R, Theiler G, Stevenson BJ, Iseli C, Gure AO, Vasicek T, Strausberg RL, Jongeneel CV, Old LJ, Simpson AJ.

Proc Natl Acad Sci U S A. 2005 May 31;102(22):7940-5. Epub 2005 May 19.


Tumor associated antigen recognition by autologous serum in patients with breast cancer.

Qian F, Odunsi K, Blatt LM, Scanlan MJ, Mannan M, Shah N, Montgomery J, Haddad F, Taylor M.

Int J Mol Med. 2005 Jan;15(1):137-44.


Real-Time, label-free monitoring of tumor antigen and serum antibody interactions.

Campagnolo C, Meyers KJ, Ryan T, Atkinson RC, Chen YT, Scanlan MJ, Ritter G, Old LJ, Batt CA.

J Biochem Biophys Methods. 2004 Nov 30;61(3):283-98.


Identification of the gonad-specific anion transporter SLCO6A1 as a cancer/testis (CT) antigen expressed in human lung cancer.

Lee SY, Williamson B, Caballero OL, Chen YT, Scanlan MJ, Ritter G, Jongeneel CV, Simpson AJ, Old LJ.

Cancer Immun. 2004 Nov 17;4:13.


SCP-1 cancer/testis antigen is a prognostic indicator and a candidate target for immunotherapy in epithelial ovarian cancer.

Tammela J, Jungbluth AA, Qian F, Santiago D, Scanlan MJ, Keitz B, Driscoll D, Rodabaugh K, Lele S, Old LJ, Odunsi K.

Cancer Immun. 2004 Oct 18;4:10.


The humoral immune response to head and neck cancer antigens as defined by the serological analysis of tumor antigens by recombinant cDNA expression cloning.

Vaughan HA, St Clair F, Scanlan MJ, Chen YT, Maraskovsky E, Sizeland A, Old LJ, Cebon J.

Cancer Immun. 2004 Jul 16;4:5.


Human Mena protein, a serex-defined antigen overexpressed in breast cancer eliciting both humoral and CD8+ T-cell immune response.

Di Modugno F, Bronzi G, Scanlan MJ, Del Bello D, Cascioli S, Venturo I, Botti C, Nicotra MR, Mottolese M, Natali PG, Santoni A, Jager E, Nisticò P.

Int J Cancer. 2004 May 10;109(6):909-18.


NY-ESO-1 expression and immunogenicity in malignant and benign breast tumors.

Sugita Y, Wada H, Fujita S, Nakata T, Sato S, Noguchi Y, Jungbluth AA, Yamaguchi M, Chen YT, Stockert E, Gnjatic S, Williamson B, Scanlan MJ, Ono T, Sakita I, Yasui M, Miyoshi Y, Tamaki Y, Matsuura N, Noguchi S, Old LJ, Nakayama E, Monden M.

Cancer Res. 2004 Mar 15;64(6):2199-204.


The cancer/testis genes: review, standardization, and commentary.

Scanlan MJ, Simpson AJ, Old LJ.

Cancer Immun. 2004 Jan 23;4:1. Review.


NY-ESO-1 and LAGE-1 cancer-testis antigens are potential targets for immunotherapy in epithelial ovarian cancer.

Odunsi K, Jungbluth AA, Stockert E, Qian F, Gnjatic S, Tammela J, Intengan M, Beck A, Keitz B, Santiago D, Williamson B, Scanlan MJ, Ritter G, Chen YT, Driscoll D, Sood A, Lele S, Old LJ.

Cancer Res. 2003 Sep 15;63(18):6076-83.


Expression of cancer/testis (CT) antigens in lung cancer.

Tajima K, Obata Y, Tamaki H, Yoshida M, Chen YT, Scanlan MJ, Old LJ, Kuwano H, Takahashi T, Takahashi T, Mitsudomi T.

Lung Cancer. 2003 Oct;42(1):23-33.


Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression.

Scanlan MJ, Gout I, Gordon CM, Williamson B, Stockert E, Gure AO, Jäger D, Chen YT, Mackay A, O'Hare MJ, Old LJ.

Cancer Immun. 2001 Mar 30;1:4.


Serological identification of antigens associated with renal cell carcinoma.

Koroleva EP, Lagarkova MA, Mesheryakov AA, Scanlan MJ, Old LJ, Nedospasov SA, Kuprash DV.

Russ J Immunol. 2002 Oct;7(3):229-38.


Immunomic analysis of human sarcoma.

Lee SY, Obata Y, Yoshida M, Stockert E, Williamson B, Jungbluth AA, Chen YT, Old LJ, Scanlan MJ.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2651-6. Epub 2003 Feb 24.


A monoclonal antibody recognizing human cancers with amplification/overexpression of the human epidermal growth factor receptor.

Jungbluth AA, Stockert E, Huang HJ, Collins VP, Coplan K, Iversen K, Kolb D, Johns TJ, Scott AM, Gullick WJ, Ritter G, Cohen L, Scanlan MJ, Cavenee WK, Old LJ.

Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):639-44. Epub 2003 Jan 6. Erratum in: Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):2163. Cavanee, Webster K [corrected to Cavenee, Webster K].


Cancer/testis antigens: an expanding family of targets for cancer immunotherapy.

Scanlan MJ, Gure AO, Jungbluth AA, Old LJ, Chen YT.

Immunol Rev. 2002 Oct;188:22-32. Review.


A new member of the NY-ESO-1 gene family is ubiquitously expressed in somatic tissues and evolutionarily conserved.

Alpen B, Güre AO, Scanlan MJ, Old LJ, Chen YT.

Gene. 2002 Sep 4;297(1-2):141-9.


Identification of breast cancer-restricted antigens by antibody screening of SKBR3 cDNA library using a preselected patient's serum.

Forti S, Scanlan MJ, Invernizzi A, Castiglioni F, Pupa S, Agresti R, Fontanelli R, Morelli D, Old LJ, Pupa SM, Ménard S.

Breast Cancer Res Treat. 2002 Jun;73(3):245-56.


Cancer-related serological recognition of human colon cancer: identification of potential diagnostic and immunotherapeutic targets.

Scanlan MJ, Welt S, Gordon CM, Chen YT, Gure AO, Stockert E, Jungbluth AA, Ritter G, Jäger D, Jäger E, Knuth A, Old LJ.

Cancer Res. 2002 Jul 15;62(14):4041-7.


Identification of cancer/testis genes by database mining and mRNA expression analysis.

Scanlan MJ, Gordon CM, Williamson B, Lee SY, Chen YT, Stockert E, Jungbluth A, Ritter G, Jäger D, Jäger E, Knuth A, Old LJ.

Int J Cancer. 2002 Apr 1;98(4):485-92.


Cloning and characterization of TNKL, a member of tankyrase gene family.

Kuimov AN, Kuprash DV, Petrov VN, Vdovichenko KK, Scanlan MJ, Jongeneel CV, Lagarkova MA, Nedospasov SA.

Genes Immun. 2001 Feb;2(1):52-5.


Identification of a tissue-specific putative transcription factor in breast tissue by serological screening of a breast cancer library.

Jäger D, Stockert E, Güre AO, Scanlan MJ, Karbach J, Jäger E, Knuth A, Old LJ, Chen YT.

Cancer Res. 2001 Mar 1;61(5):2055-61.


Challenges to the development of antigen-specific breast cancer vaccines.

Scanlan MJ, Jäger D.

Breast Cancer Res. 2001;3(2):95-8. Epub 2001 Jan 11. Review.


A recessive contiguous gene deletion causing infantile hyperinsulinism, enteropathy and deafness identifies the Usher type 1C gene.

Bitner-Glindzicz M, Lindley KJ, Rutland P, Blaydon D, Smith VV, Milla PJ, Hussain K, Furth-Lavi J, Cosgrove KE, Shepherd RM, Barnes PD, O'Brien RE, Farndon PA, Sowden J, Liu XZ, Scanlan MJ, Malcolm S, Dunne MJ, Aynsley-Green A, Glaser B.

Nat Genet. 2000 Sep;26(1):56-60.


Serological cloning of a melanocyte rab guanosine 5'-triphosphate-binding protein and a chromosome condensation protein from a melanoma complementary DNA library.

Jäger D, Stockert E, Jäger E, Güre AO, Scanlan MJ, Knuth A, Old LJ, Chen YT.

Cancer Res. 2000 Jul 1;60(13):3584-91.


Serological identification of embryonic neural proteins as highly immunogenic tumor antigens in small cell lung cancer.

Güre AO, Stockert E, Scanlan MJ, Keresztes RS, Jäger D, Altorki NK, Old LJ, Chen YT.

Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4198-203.


Expression of cancer-testis antigens in lung cancer: definition of bromodomain testis-specific gene (BRDT) as a new CT gene, CT9.

Scanlan MJ, Altorki NK, Gure AO, Williamson B, Jungbluth A, Chen YT, Old LJ.

Cancer Lett. 2000 Mar 31;150(2):155-64.


CT10: a new cancer-testis (CT) antigen homologous to CT7 and the MAGE family, identified by representational-difference analysis.

Güre AO, Stockert E, Arden KC, Boyer AD, Viars CS, Scanlan MJ, Old LJ, Chen YT.

Int J Cancer. 2000 Mar 1;85(5):726-32.


Cancer-testis antigens and ING1 tumor suppressor gene product are breast cancer antigens: characterization of tissue-specific ING1 transcripts and a homologue gene.

Jäger D, Stockert E, Scanlan MJ, Güre AO, Jäger E, Knuth A, Old LJ, Chen YT.

Cancer Res. 1999 Dec 15;59(24):6197-204.


Antigens recognized by autologous antibody in patients with renal-cell carcinoma.

Scanlan MJ, Gordan JD, Williamson B, Stockert E, Bander NH, Jongeneel V, Gure AO, Jäger D, Jäger E, Knuth A, Chen YT, Old LJ.

Int J Cancer. 1999 Nov 12;83(4):456-64.


Isoforms of the human PDZ-73 protein exhibit differential tissue expression.

Scanlan MJ, Williamson B, Jungbluth A, Stockert E, Arden KC, Viars CS, Gure AO, Gordan JD, Chen YT, Old LJ.

Biochim Biophys Acta. 1999 Apr 14;1445(1):39-52.


Characterization of human colon cancer antigens recognized by autologous antibodies.

Scanlan MJ, Chen YT, Williamson B, Gure AO, Stockert E, Gordan JD, Türeci O, Sahin U, Pfreundschuh M, Old LJ.

Int J Cancer. 1998 May 29;76(5):652-8.


A survey of the humoral immune response of cancer patients to a panel of human tumor antigens.

Stockert E, Jäger E, Chen YT, Scanlan MJ, Gout I, Karbach J, Arand M, Knuth A, Old LJ.

J Exp Med. 1998 Apr 20;187(8):1349-54.


SSX: a multigene family with several members transcribed in normal testis and human cancer.

Gure AO, Türeci O, Sahin U, Tsang S, Scanlan MJ, Jäger E, Knuth A, Pfreundschuh M, Old LJ, Chen YT.

Int J Cancer. 1997 Sep 17;72(6):965-71.


Mouse fibroblast activation protein: molecular cloning, alternative splicing and expression in the reactive stroma of epithelial cancers.

Niedermeyer J, Scanlan MJ, Garin-Chesa P, Daiber C, Fiebig HH, Old LJ, Rettig WJ, Schnapp A.

Int J Cancer. 1997 May 2;71(3):383-9.


A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening.

Chen YT, Scanlan MJ, Sahin U, Türeci O, Gure AO, Tsang S, Williamson B, Stockert E, Pfreundschuh M, Old LJ.

Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1914-8.


Serological analysis of Melan-A(MART-1), a melanocyte-specific protein homogeneously expressed in human melanomas.

Chen YT, Stockert E, Jungbluth A, Tsang S, Coplan KA, Scanlan MJ, Old LJ.

Proc Natl Acad Sci U S A. 1996 Jun 11;93(12):5915-9.


The gene for fibroblast activation protein alpha (FAP), a putative cell surface-bound serine protease expressed in cancer stroma and wound healing, maps to chromosome band 2q23.

Mathew S, Scanlan MJ, Mohan Raj BK, Murty VV, Garin-Chesa P, Old LJ, Rettig WJ, Chaganti RS.

Genomics. 1995 Jan 1;25(1):335-7. No abstract available.


Fibroblast activation protein: purification, epitope mapping and induction by growth factors.

Rettig WJ, Su SL, Fortunato SR, Scanlan MJ, Raj BK, Garin-Chesa P, Healey JH, Old LJ.

Int J Cancer. 1994 Aug 1;58(3):385-92.


Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers.

Scanlan MJ, Raj BK, Calvo B, Garin-Chesa P, Sanz-Moncasi MP, Healey JH, Old LJ, Rettig WJ.

Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5657-61.

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