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Items: 50

1.

Patterns of Failure in Patients With Double Hit or Double Expressor Lymphomas: Implications for Radiation Therapy.

Tumati V, Trivedi L, Li HC, Patel P, Scaglioni PP, Vusirikala M, Sadeghi N, Rizvi S, Chen W, Wachsmann J, Collins R Jr, Desai NB.

Int J Radiat Oncol Biol Phys. 2018 Apr 1;100(5):1126-1132. doi: 10.1016/j.ijrobp.2018.01.041. Epub 2018 Jan 31.

PMID:
29722657
2.

Therapeutic Targeting of Nuclear Export Inhibition in Lung Cancer.

Gupta A, Saltarski JM, White MA, Scaglioni PP, Gerber DE.

J Thorac Oncol. 2017 Sep;12(9):1446-1450. doi: 10.1016/j.jtho.2017.06.013. Epub 2017 Jun 21. Review.

PMID:
28647672
3.

The Role of PIAS SUMO E3-Ligases in Cancer.

Rabellino A, Andreani C, Scaglioni PP.

Cancer Res. 2017 Apr 1;77(7):1542-1547. doi: 10.1158/0008-5472.CAN-16-2958. Epub 2017 Mar 22. Review.

4.

XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.

Kim J, McMillan E, Kim HS, Venkateswaran N, Makkar G, Rodriguez-Canales J, Villalobos P, Neggers JE, Mendiratta S, Wei S, Landesman Y, Senapedis W, Baloglu E, Chow CB, Frink RE, Gao B, Roth M, Minna JD, Daelemans D, Wistuba II, Posner BA, Scaglioni PP, White MA.

Nature. 2016 Oct 6;538(7623):114-117. doi: 10.1038/nature19771. Epub 2016 Sep 28.

5.

Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.

Padanad MS, Konstantinidou G, Venkateswaran N, Melegari M, Rindhe S, Mitsche M, Yang C, Batten K, Huffman KE, Liu J, Tang X, Rodriguez-Canales J, Kalhor N, Shay JW, Minna JD, McDonald J, Wistuba II, DeBerardinis RJ, Scaglioni PP.

Cell Rep. 2016 Aug 9;16(6):1614-1628. doi: 10.1016/j.celrep.2016.07.009. Epub 2016 Jul 28.

6.

PIAS1 Promotes Lymphomagenesis through MYC Upregulation.

Rabellino A, Melegari M, Tompkins VS, Chen W, Van Ness BG, Teruya-Feldstein J, Conacci-Sorrell M, Janz S, Scaglioni PP.

Cell Rep. 2016 Jun 7;15(10):2266-2278. doi: 10.1016/j.celrep.2016.05.015. Epub 2016 May 26.

7.

PIAS1-FAK Interaction Promotes the Survival and Progression of Non-Small Cell Lung Cancer.

Constanzo JD, Tang KJ, Rindhe S, Melegari M, Liu H, Tang X, Rodriguez-Canales J, Wistuba I, Scaglioni PP.

Neoplasia. 2016 May;18(5):282-293. doi: 10.1016/j.neo.2016.03.003. Epub 2016 Apr 16.

8.

Focal Adhesion Kinase Regulates the DNA Damage Response and Its Inhibition Radiosensitizes Mutant KRAS Lung Cancer.

Tang KJ, Constanzo JD, Venkateswaran N, Melegari M, Ilcheva M, Morales JC, Skoulidis F, Heymach JV, Boothman DA, Scaglioni PP.

Clin Cancer Res. 2016 Dec 1;22(23):5851-5863. Epub 2016 May 24.

9.

Pias1 is essential for erythroid and vascular development in the mouse embryo.

Constanzo JD, Deng M, Rindhe S, Tang KJ, Zhang CC, Scaglioni PP.

Dev Biol. 2016 Jul 1;415(1):98-110. doi: 10.1016/j.ydbio.2016.04.013. Epub 2016 May 4.

10.

Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone.

Chakrabarti G, Moore ZR, Luo X, Ilcheva M, Ali A, Padanad M, Zhou Y, Xie Y, Burma S, Scaglioni PP, Cantley LC, DeBerardinis RJ, Kimmelman AC, Lyssiotis CA, Boothman DA.

Cancer Metab. 2015 Oct 12;3:12. doi: 10.1186/s40170-015-0137-1. eCollection 2015.

11.

Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells.

Rajagopalan KN, Egnatchik RA, Calvaruso MA, Wasti AT, Padanad MS, Boroughs LK, Ko B, Hensley CT, Acar M, Hu Z, Jiang L, Pascual JM, Scaglioni PP, DeBerardinis RJ.

Cancer Metab. 2015 Jun 29;3:7. doi: 10.1186/s40170-015-0134-4. eCollection 2015.

12.

Diet-induced unresolved ER stress hinders KRAS-driven lung tumorigenesis.

Ramadori G, Konstantinidou G, Venkateswaran N, Biscotti T, Morlock L, Galié M, Williams NS, Luchetti M, Santinelli A, Scaglioni PP, Coppari R.

Cell Metab. 2015 Jan 6;21(1):117-25. doi: 10.1016/j.cmet.2014.11.020. Epub 2014 Dec 18.

13.

Nullifying the CDKN2AB locus promotes mutant K-ras lung tumorigenesis.

Schuster K, Venkateswaran N, Rabellino A, Girard L, Peña-Llopis S, Scaglioni PP.

Mol Cancer Res. 2014 Jun;12(6):912-23. doi: 10.1158/1541-7786.MCR-13-0620-T. Epub 2014 Mar 11.

14.

PML Degradation: Multiple Ways to Eliminate PML.

Rabellino A, Scaglioni PP.

Front Oncol. 2013 Mar 22;3:60. doi: 10.3389/fonc.2013.00060. eCollection 2013.

15.

RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven lung adenocarcinomas.

Konstantinidou G, Ramadori G, Torti F, Kangasniemi K, Ramirez RE, Cai Y, Behrens C, Dellinger MT, Brekken RA, Wistuba II, Heguy A, Teruya-Feldstein J, Scaglioni PP.

Cancer Discov. 2013 Apr;3(4):444-57. doi: 10.1158/2159-8290.CD-12-0388. Epub 2013 Jan 28.

16.

Selective targeting of the mTORC1/2 protein kinase complexes leads to antileukemic effects in vitro and in vivo.

Schuster K, Zheng J, Arbini AA, Zhang CC, Scaglioni PP.

Blood Cancer J. 2011 Sep;1(9):e34. doi: 10.1038/bcj.2011.30. Epub 2011 Sep 2.

17.

The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA.

Rabellino A, Carter B, Konstantinidou G, Wu SY, Rimessi A, Byers LA, Heymach JV, Girard L, Chiang CM, Teruya-Feldstein J, Scaglioni PP.

Cancer Res. 2012 May 1;72(9):2275-84. doi: 10.1158/0008-5472.CAN-11-3159. Epub 2012 Mar 9.

18.

Translation-dependent mechanisms lead to PML upregulation and mediate oncogenic K-RAS-induced cellular senescence.

Scaglioni PP, Rabellino A, Yung TM, Bernardi R, Choi S, Konstantinidou G, Nardella C, Cheng K, Pandolfi PP.

EMBO Mol Med. 2012 Jul;4(7):594-602. doi: 10.1002/emmm.201200233. Epub 2012 Mar 21.

19.

Treatment with 5-azacytidine accelerates acute promyelocytic leukemia leukemogenesis in a transgenic mouse model.

Scaglioni PP, Cai LF, Majid SM, Yung TM, Socci ND, Kogan SC, Kopelovich L, Pandolfi PP.

Genes Cancer. 2011 Feb;2(2):160-5. doi: 10.1177/1947601911410300.

20.

Successful treatment of relapsed and refractory extramedullary acute promyelocytic leukemia with tamibarotene.

Naina HV, Levitt D, Vusirikala M, Anderson LD Jr, Scaglioni PP, Kirk A, Collins RH Jr.

J Clin Oncol. 2011 Jun 20;29(18):e534-6. doi: 10.1200/JCO.2011.34.8953. Epub 2011 Apr 11. No abstract available.

PMID:
21482998
21.

Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.

Sullivan JP, Spinola M, Dodge M, Raso MG, Behrens C, Gao B, Schuster K, Shao C, Larsen JE, Sullivan LA, Honorio S, Xie Y, Scaglioni PP, DiMaio JM, Gazdar AF, Shay JW, Wistuba II, Minna JD.

Cancer Res. 2010 Dec 1;70(23):9937-48. doi: 10.1158/0008-5472.CAN-10-0881. Epub 2010 Nov 30.

22.

Dual phosphoinositide 3-kinase/mammalian target of rapamycin blockade is an effective radiosensitizing strategy for the treatment of non-small cell lung cancer harboring K-RAS mutations.

Konstantinidou G, Bey EA, Rabellino A, Schuster K, Maira MS, Gazdar AF, Amici A, Boothman DA, Scaglioni PP.

Cancer Res. 2009 Oct 1;69(19):7644-52. doi: 10.1158/0008-5472.CAN-09-0823. Epub 2009 Sep 29.

23.

CK2 mediates phosphorylation and ubiquitin-mediated degradation of the PML tumor suppressor.

Scaglioni PP, Yung TM, Choi S, Baldini C, Konstantinidou G, Pandolfi PP.

Mol Cell Biochem. 2008 Sep;316(1-2):149-54. doi: 10.1007/s11010-008-9812-7. Epub 2008 Jun 20. Erratum in: Mol Cell Biochem. 2009 Jul;327(1-2):279. Choi, S C [corrected to Choi, S].

PMID:
18566754
24.

The theory of APL revisited.

Scaglioni PP, Pandolfi PP.

Curr Top Microbiol Immunol. 2007;313:85-100. Review.

PMID:
17217040
25.

The Mechanisms of PML-Nuclear Body Formation.

Shen TH, Lin HK, Scaglioni PP, Yung TM, Pandolfi PP.

Mol Cell. 2006 Dec 8;24(5):805. doi: 10.1016/j.molcel.2006.11.010. Epub 2006 Dec 7. No abstract available.

26.

The mechanisms of PML-nuclear body formation.

Shen TH, Lin HK, Scaglioni PP, Yung TM, Pandolfi PP.

Mol Cell. 2006 Nov 3;24(3):331-9. Erratum in: Mol Cell. 2006 Dec 8;24(5):805.

27.

A CK2-dependent mechanism for degradation of the PML tumor suppressor.

Scaglioni PP, Yung TM, Cai LF, Erdjument-Bromage H, Kaufman AJ, Singh B, Teruya-Feldstein J, Tempst P, Pandolfi PP.

Cell. 2006 Jul 28;126(2):269-83.

28.

Identification of a tumour suppressor network opposing nuclear Akt function.

Trotman LC, Alimonti A, Scaglioni PP, Koutcher JA, Cordon-Cardo C, Pandolfi PP.

Nature. 2006 May 25;441(7092):523-7. Epub 2006 May 7.

29.

In vivo analysis of the role of aberrant histone deacetylase recruitment and RAR alpha blockade in the pathogenesis of acute promyelocytic leukemia.

Matsushita H, Scaglioni PP, Bhaumik M, Rego EM, Cai LF, Majid SM, Miyachi H, Kakizuka A, Miller WH Jr, Pandolfi PP.

J Exp Med. 2006 Apr 17;203(4):821-8. Epub 2006 Mar 20.

30.

PML regulates p53 stability by sequestering Mdm2 to the nucleolus.

Bernardi R, Scaglioni PP, Bergmann S, Horn HF, Vousden KH, Pandolfi PP.

Nat Cell Biol. 2004 Jul;6(7):665-72. Epub 2004 Jun 13.

PMID:
15195100
31.

Loss of the tumor suppressor PML in human cancers of multiple histologic origins.

Gurrieri C, Capodieci P, Bernardi R, Scaglioni PP, Nafa K, Rush LJ, Verbel DA, Cordon-Cardo C, Pandolfi PP.

J Natl Cancer Inst. 2004 Feb 18;96(4):269-79.

PMID:
14970276
32.

Medicine: taking apart a cancer protein.

Scaglioni PP, Pandolfi PP.

Nature. 2003 Dec 4;426(6966):512-3. No abstract available.

PMID:
14654828
33.

Cationic liposome-mediated gene delivery to the liver and to hepatocellular carcinomas in mice.

Mohr L, Yoon SK, Eastman SJ, Chu Q, Scheule RK, Scaglioni PP, Geissler M, Heintges T, Blum HE, Wands JR.

Hum Gene Ther. 2001 May 1;12(7):799-809.

PMID:
11339896
34.
35.

Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective.

Melegari M, Scaglioni PP, Wands JR.

Hepatology. 1998 Feb;27(2):628-33.

PMID:
9462667
36.

Nucleic acid-based antiviral and gene therapy of chronic hepatitis B infection.

Wands JR, Geissler M, Putlitz JZ, Blum H, von Weizsäcker F, Mohr L, Yoon SK, Melegari M, Scaglioni PP.

J Gastroenterol Hepatol. 1997 Oct;12(9-10):S354-69. Review.

PMID:
9407358
37.
38.
39.

Posttranscriptional regulation of hepatitis B virus replication by the precore protein.

Scaglioni PP, Melegari M, Wands JR.

J Virol. 1997 Jan;71(1):345-53.

40.

Recent advances in the molecular biology of hepatitis B virus.

Scaglioni PP, Melegari M, Wands JR.

Baillieres Clin Gastroenterol. 1996 Jul;10(2):207-25. Review.

PMID:
8864030
41.

Characterization of hepatitis B virus core mutants that inhibit viral replication.

Scaglioni PP, Melegari M, Wands JR.

Virology. 1994 Nov 15;205(1):112-20.

PMID:
7975206
42.

Hepatitis B virus specific transcripts in peripheral blood mononuclear cells.

Melegari M, Scaglioni PP, Pasquinelli C, Manenti F, Villa E.

Arch Virol Suppl. 1992;4:46-9.

PMID:
1450723
43.

Presence of HCV RNA in serum of asymptomatic blood donors involved in post-transfusion hepatitis (PTH).

Villa E, Melegari M, Ferretti I, Vecchi C, Scaglioni PP, De Palma M, Manenti F.

Arch Virol Suppl. 1992;4:247-8.

PMID:
1450695
44.

Conserved core protein sequences in hepatitis B virus infected patients without anti-HBc.

Melegari M, Jung MC, Schneider R, Santantonio T, Bagnulo S, Luchena N, Pastore G, Pape G, Scaglioni PP, Villa E, et al.

J Hepatol. 1991 Sep;13(2):187-91. Erratum in: J Hepatol 1992 Jan;14(1):137.

PMID:
1744423
45.

HCV RNA in serum of asymptomatic blood donors involved in post-transfusion hepatitis (PTH).

Villa E, Ferretti I, De Palma M, Melegari M, Scaglioni PP, Trande P, Vecchi C, Fratti N, Manenti F.

J Hepatol. 1991 Sep;13(2):256-9.

PMID:
1660505
46.

Hepatocellular carcinoma: risk factors other than HBV.

Villa E, Melegari M, Scaglioni PP, Trande P, Cesaro P, Manenti F.

Ital J Gastroenterol. 1991 Sep-Oct;23(7):457-60.

PMID:
1660333
47.

Hepatitis B virus infection of peripheral blood mononuclear cells is common in acute and chronic hepatitis.

Pasquinelli C, Melegari M, Villa E, Scaglioni PP, Seidenari M, Mongiardo N, De Rienzo B, Manenti F.

J Med Virol. 1990 Jun;31(2):135-40.

PMID:
2388045
48.

[Estrogen receptors in the human liver].

Melegari M, Scaglioni PP, Mao GP, Pasquinelli C, Baldini G.

Medicina (Firenze). 1990 Apr-Jun;10(2):154-7. Italian.

PMID:
2177131
49.

Detection of hepatitis B virus transcripts in patients with chronic liver disease.

Pasquinelli C, Melegari M, Villa E, Seidenari M, Scaglioni PP, Tiribelli C, Crocé LS, Manenti F.

J Hepatol. 1990 Mar;10(2):180-5.

PMID:
2332589
50.

[HBV DNA in mononuclear cells of peripheral blood in acute hepatitis B: a comparative analysis of Southern blot and polymerase chain reaction (PCR)].

Scaglioni PP, Melegari M, Mao G, Pasquinelli C.

Medicina (Firenze). 1990 Jan-Mar;10(1):32-4. Italian.

PMID:
2381278

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