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Items: 1 to 50 of 62

1.

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.

Shi Y, Gao W, Lytle NK, Huang P, Yuan X, Dann AM, Ridinger-Saison M, DelGiorno KE, Antal CE, Liang G, Atkins AR, Erikson G, Sun H, Meisenhelder J, Terenziani E, Woo G, Fang L, Santisakultarm TP, Manor U, Xu R, Becerra CR, Borazanci E, Von Hoff DD, Grandgenett PM, Hollingsworth MA, Leblanc M, Umetsu SE, Collisson EA, Scadeng M, Lowy AM, Donahue TR, Reya T, Downes M, Evans RM, Wahl GM, Pawson T, Tian R, Hunter T.

Nature. 2019 May;569(7754):131-135. doi: 10.1038/s41586-019-1130-6. Epub 2019 Apr 17.

PMID:
30996350
2.

Awake Mouse Imaging: From Two-Photon Microscopy to Blood Oxygen Level-Dependent Functional Magnetic Resonance Imaging.

Desjardins M, Kılıç K, Thunemann M, Mateo C, Holland D, Ferri CGL, Cremonesi JA, Li B, Cheng Q, Weldy KL, Saisan PA, Kleinfeld D, Komiyama T, Liu TT, Bussell R, Wong EC, Scadeng M, Dunn AK, Boas DA, Sakadžić S, Mandeville JB, Buxton RB, Dale AM, Devor A.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 Jun;4(6):533-542. doi: 10.1016/j.bpsc.2018.12.002. Epub 2018 Dec 12.

PMID:
30691968
3.

Diffusion tractography reveals pervasive asymmetry of cerebral white matter tracts in the bottlenose dolphin (Tursiops truncatus).

Wright AK, Theilmann RJ, Ridgway SH, Scadeng M.

Brain Struct Funct. 2018 May;223(4):1697-1711. doi: 10.1007/s00429-017-1525-9. Epub 2017 Nov 30.

4.

Respiratory mechanics and morphology of Tibetan and Andean high-altitude geese with divergent life histories.

York JM, Scadeng M, McCracken KG, Milsom WK.

J Exp Biol. 2018 Jan 10;221(Pt 1). pii: jeb170738. doi: 10.1242/jeb.170738.

5.

Evidence from high-altitude acclimatization for an integrated cerebrovascular and ventilatory hypercapnic response but different responses to hypoxia.

Smith ZM, Krizay E, Sá RC, Li ET, Scadeng M, Powell FL Jr, Dubowitz DJ.

J Appl Physiol (1985). 2017 Dec 1;123(6):1477-1486. doi: 10.1152/japplphysiol.00341.2017. Epub 2017 Jul 13.

6.

Skeletal myofiber vascular endothelial growth factor is required for the exercise training-induced increase in dentate gyrus neuronal precursor cells.

Rich B, Scadeng M, Yamaguchi M, Wagner PD, Breen EC.

J Physiol. 2017 Sep 1;595(17):5931-5943. doi: 10.1113/JP273994. Epub 2017 Jun 28.

7.

Functional magnetic resonance imaging for in vivo quantification of pulmonary hypertension in the Sugen 5416/hypoxia mouse.

Breen EC, Scadeng M, Lai NC, Murray F, Bigby TD.

Exp Physiol. 2017 Mar 1;102(3):347-353. doi: 10.1113/EP086067. Epub 2017 Feb 14.

8.

A murine model of inflammation-induced cerebral microbleeds.

Sumbria RK, Grigoryan MM, Vasilevko V, Krasieva TB, Scadeng M, Dvornikova AK, Paganini-Hill A, Kim R, Cribbs DH, Fisher MJ.

J Neuroinflammation. 2016 Aug 30;13(1):218. doi: 10.1186/s12974-016-0693-5.

9.

Polymeric Gd-DOTA amphiphiles form spherical and fibril-shaped nanoparticle MRI contrast agents.

Randolph LM, LeGuyader CLM, Hahn ME, Andolina CM, Patterson JP, Mattrey RF, Millstone JE, Botta M, Scadeng M, Gianneschi NC.

Chem Sci. 2016 Jul 1;7(7):4230-4236. doi: 10.1039/c6sc00342g. Epub 2016 Mar 22.

10.

Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.

Fox RG, Lytle NK, Jaquish DV, Park FD, Ito T, Bajaj J, Koechlein CS, Zimdahl B, Yano M, Kopp J, Kritzik M, Sicklick J, Sander M, Grandgenett PM, Hollingsworth MA, Shibata S, Pizzo D, Valasek M, Sasik R, Scadeng M, Okano H, Kim Y, MacLeod AR, Lowy AM, Reya T.

Nature. 2016 Jun 16;534(7607):407-411. doi: 10.1038/nature17988. Epub 2016 Jun 6.

11.

Intrathecal Catheterization and Drug Delivery in Guinea Pigs: A Small-animal Model for Morphine-evoked Granuloma Formation.

Eddinger KA, Rondon ES, Shubayev VI, Grafe MR, Scadeng M, Hildebrand KR, Page LM, Malkmus SA, Steinauer JJ, Yaksh TL.

Anesthesiology. 2016 Aug;125(2):378-94. doi: 10.1097/ALN.0000000000001166.

PMID:
27272672
12.

Neuroanatomy of the killer whale (Orcinus orca): a magnetic resonance imaging investigation of structure with insights on function and evolution.

Wright A, Scadeng M, Stec D, Dubowitz R, Ridgway S, Leger JS.

Brain Struct Funct. 2017 Jan;222(1):417-436. doi: 10.1007/s00429-016-1225-x. Epub 2016 Apr 27.

PMID:
27119362
13.

Microstructural changes to the brain of mice after methamphetamine exposure as identified with diffusion tensor imaging.

McKenna BS, Brown GG, Archibald S, Scadeng M, Bussell R, Kesby JP, Markou A, Soontornniyomkij V, Achim C, Semenova S; Translational Methamphetamine Aids Research Center Tmarc Group.

Psychiatry Res Neuroimaging. 2016 Mar 30;249:27-37. doi: 10.1016/j.pscychresns.2016.02.009. Epub 2016 Feb 24.

14.

p75 Neurotrophin Receptor Regulates Energy Balance in Obesity.

Baeza-Raja B, Sachs BD, Li P, Christian F, Vagena E, Davalos D, Le Moan N, Ryu JK, Sikorski SL, Chan JP, Scadeng M, Taylor SS, Houslay MD, Baillie GS, Saltiel AR, Olefsky JM, Akassoglou K.

Cell Rep. 2016 Jan 12;14(2):255-68. doi: 10.1016/j.celrep.2015.12.028. Epub 2015 Dec 31.

15.

Polycatechol Nanoparticle MRI Contrast Agents.

Li Y, Huang Y, Wang Z, Carniato F, Xie Y, Patterson JP, Thompson MP, Andolina CM, Ditri TB, Millstone JE, Figueroa JS, Rinehart JD, Scadeng M, Botta M, Gianneschi NC.

Small. 2016 Feb 3;12(5):668-77. doi: 10.1002/smll.201502754. Epub 2015 Dec 17.

16.

Multiple spatially related pharmacophores define small molecule inhibitors of OLIG2 in glioblastoma.

Tsigelny IF, Mukthavaram R, Kouznetsova VL, Chao Y, Babic I, Nurmemmedov E, Pastorino S, Jiang P, Calligaris D, Agar N, Scadeng M, Pingle SC, Wrasidlo W, Makale MT, Kesari S.

Oncotarget. 2017 Apr 4;8(14):22370-22384. doi: 10.18632/oncotarget.5633.

17.

Spatial Cognition in Adult and Aged Mice Exposed to High-Fat Diet.

Kesby JP, Kim JJ, Scadeng M, Woods G, Kado DM, Olefsky JM, Jeste DV, Achim CL, Semenova S.

PLoS One. 2015 Oct 8;10(10):e0140034. doi: 10.1371/journal.pone.0140034. eCollection 2015.

18.

Doxycycline Inducible Melanogenic Vaccinia Virus as Theranostic Anti-Cancer Agent.

Kirscher L, Deán-Ben XL, Scadeng M, Zaremba A, Zhang Q, Kober C, Fehm TF, Razansky D, Ntziachristos V, Stritzker J, Szalay AA.

Theranostics. 2015 Jun 15;5(10):1045-57. doi: 10.7150/thno.12533. eCollection 2015.

19.

Penguin lungs and air sacs: implications for baroprotection, oxygen stores and buoyancy.

Ponganis PJ, St Leger J, Scadeng M.

J Exp Biol. 2015 Mar;218(Pt 5):720-30. doi: 10.1242/jeb.113647.

20.

Clostridium perfringens septicemia in a long-beaked common dolphin Delphinus capensis: an etiology of gas bubble accumulation in cetaceans.

Danil K, St Leger JA, Dennison S, Bernaldo de Quirós Y, Scadeng M, Nilson E, Beaulieu N.

Dis Aquat Organ. 2014 Oct 16;111(3):183-90. doi: 10.3354/dao02783.

21.

Increase in relative deposition of fine particles in the rat lung periphery in the absence of gravity.

Darquenne C, Borja MG, Oakes JM, Breen EC, Olfert IM, Scadeng M, Prisk GK.

J Appl Physiol (1985). 2014 Oct 15;117(8):880-6. doi: 10.1152/japplphysiol.00298.2014. Epub 2014 Aug 28.

22.

MRI-based measurements of aerosol deposition in the lung of healthy and elastase-treated rats.

Oakes JM, Breen EC, Scadeng M, Tchantchou GS, Darquenne C.

J Appl Physiol (1985). 2014 Jun 15;116(12):1561-8. doi: 10.1152/japplphysiol.01165.2013. Epub 2014 May 1.

23.

Dipeptidyl peptidase IV inhibitor lowers PPARγ agonist-induced body weight gain by affecting food intake, fat mass, and beige/brown fat but not fluid retention.

Masuda T, Fu Y, Eguchi A, Czogalla J, Rose MA, Kuczkowski A, Gerasimova M, Feldstein AE, Scadeng M, Vallon V.

Am J Physiol Endocrinol Metab. 2014 Feb 15;306(4):E388-98. doi: 10.1152/ajpendo.00124.2013. Epub 2013 Dec 17.

24.

Ocular integrity following manganese labeling of the visual system for MRI.

Lindsey JD, Grob SR, Scadeng M, Duong-Polk K, Weinreb RN.

Magn Reson Imaging. 2013 Jul;31(6):865-74. doi: 10.1016/j.mri.2012.11.012. Epub 2013 Mar 27.

PMID:
23541073
25.

Role of meningeal mast cells in intrathecal morphine-evoked granuloma formation.

Yaksh TL, Allen JW, Veesart SL, Horais KA, Malkmus SA, Scadeng M, Steinauer JJ, Rossi SS.

Anesthesiology. 2013 Mar;118(3):664-78. doi: 10.1097/ALN.0b013e31828351aa.

26.

Vaccinia virus-mediated melanin production allows MR and optoacoustic deep tissue imaging and laser-induced thermotherapy of cancer.

Stritzker J, Kirscher L, Scadeng M, Deliolanis NC, Morscher S, Symvoulidis P, Schaefer K, Zhang Q, Buckel L, Hess M, Donat U, Bradley WG, Ntziachristos V, Szalay AA.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3316-20. doi: 10.1073/pnas.1216916110. Epub 2013 Feb 11.

27.

Regional distribution of aerosol deposition in rat lungs using magnetic resonance imaging.

Oakes JM, Scadeng M, Breen EC, Prisk GK, Darquenne C.

Ann Biomed Eng. 2013 May;41(5):967-78. doi: 10.1007/s10439-013-0745-2. Epub 2013 Jan 25.

28.

Cerebral diffusion and T(2): MRI predictors of acute mountain sickness during sustained high-altitude hypoxia.

Hunt JS Jr, Theilmann RJ, Smith ZM, Scadeng M, Dubowitz DJ.

J Cereb Blood Flow Metab. 2013 Mar;33(3):372-80. doi: 10.1038/jcbfm.2012.184. Epub 2012 Dec 5.

29.

Sustained high-altitude hypoxia increases cerebral oxygen metabolism.

Smith ZM, Krizay E, Guo J, Shin DD, Scadeng M, Dubowitz DJ.

J Appl Physiol (1985). 2013 Jan 1;114(1):11-8. doi: 10.1152/japplphysiol.00703.2012. Epub 2012 Sep 27. Erratum in: J Appl Physiol. 2013 Mar 15;114(6):832.

30.

Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3.

Lee JH, Budanov AV, Talukdar S, Park EJ, Park HL, Park HW, Bandyopadhyay G, Li N, Aghajan M, Jang I, Wolfe AM, Perkins GA, Ellisman MH, Bier E, Scadeng M, Foretz M, Viollet B, Olefsky J, Karin M.

Cell Metab. 2012 Sep 5;16(3):311-21. doi: 10.1016/j.cmet.2012.08.004.

31.

Development of AMPA receptor and GABA B receptor-sensitive spinal hyper-reflexia after spinal air embolism in rat: a systematic neurological, electrophysiological and qualitative histopathological study.

Kakinohana O, Scadeng M, Corleto JA, Sevc J, Lukacova N, Marsala M.

Exp Neurol. 2012 Sep;237(1):26-35. doi: 10.1016/j.expneurol.2012.06.004. Epub 2012 Jun 18.

32.

G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice.

Osborn O, Oh DY, McNelis J, Sanchez-Alavez M, Talukdar S, Lu M, Li P, Thiede L, Morinaga H, Kim JJ, Heinrichsdorff J, Nalbandian S, Ofrecio JM, Scadeng M, Schenk S, Hadcock J, Bartfai T, Olefsky JM.

J Clin Invest. 2012 Jul;122(7):2444-53. doi: 10.1172/JCI61953. Epub 2012 Jun 1.

33.

Rat airway morphometry measured from in situ MRI-based geometric models.

Oakes JM, Scadeng M, Breen EC, Marsden AL, Darquenne C.

J Appl Physiol (1985). 2012 Jun;112(11):1921-31. doi: 10.1152/japplphysiol.00018.2012. Epub 2012 Mar 29.

34.

A frameless stereotaxic MRI technique for macaque neuroscience studies.

Dubowitz DJ, Scadeng M.

Open Neuroimag J. 2011;5:198-205. doi: 10.2174/1874440001105010198. Epub 2011 Nov 18.

35.

Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity.

Li P, Fan W, Xu J, Lu M, Yamamoto H, Auwerx J, Sears DD, Talukdar S, Oh D, Chen A, Bandyopadhyay G, Scadeng M, Ofrecio JM, Nalbandian S, Olefsky JM.

Cell. 2011 Nov 11;147(4):815-26. doi: 10.1016/j.cell.2011.09.050.

36.

Chronic spinal compression model in minipigs: a systematic behavioral, qualitative, and quantitative neuropathological study.

Navarro R, Juhas S, Keshavarzi S, Juhasova J, Motlik J, Johe K, Marsala S, Scadeng M, Lazar P, Tomori Z, Schulteis G, Beattie M, Ciacci JD, Marsala M.

J Neurotrauma. 2012 Feb 10;29(3):499-513. doi: 10.1089/neu.2011.2076. Epub 2012 Jan 13.

37.

Magnetic resonance imaging of tumors colonized with bacterial ferritin-expressing Escherichia coli.

Hill PJ, Stritzker J, Scadeng M, Geissinger U, Haddad D, Basse-Lüsebrink TC, Gbureck U, Jakob P, Szalay AA.

PLoS One. 2011;6(10):e25409. doi: 10.1371/journal.pone.0025409. Epub 2011 Oct 3.

38.

Enhanced magnetic resonance contrast of Fe₃O₄ nanoparticles trapped in a porous silicon nanoparticle host.

Kinsella JM, Ananda S, Andrew JS, Grondek JF, Chien MP, Scadeng M, Gianneschi NC, Ruoslahti E, Sailor MJ.

Adv Mater. 2011 Sep 22;23(36):H248-53. doi: 10.1002/adma.201101877. Epub 2011 Aug 15. No abstract available.

39.

Cortical depth-specific microvascular dilation underlies laminar differences in blood oxygenation level-dependent functional MRI signal.

Tian P, Teng IC, May LD, Kurz R, Lu K, Scadeng M, Hillman EM, De Crespigny AJ, D'Arceuil HE, Mandeville JB, Marota JJ, Rosen BR, Liu TT, Boas DA, Buxton RB, Dale AM, Devor A.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15246-51. doi: 10.1073/pnas.1006735107. Epub 2010 Aug 9.

40.

Magnetic resonance and fluorescence imaging of doxorubicin-loaded nanoparticles using a novel in vivo model.

Erten A, Wrasidlo W, Scadeng M, Esener S, Hoffman RM, Bouvet M, Makale M.

Nanomedicine. 2010 Dec;6(6):797-807. doi: 10.1016/j.nano.2010.06.005. Epub 2010 Jul 3.

41.

Analysis of dosing regimen and reproducibility of intraspinal grafting of human spinal stem cells in immunosuppressed minipigs.

Usvald D, Vodicka P, Hlucilova J, Prochazka R, Motlik J, Kuchorova K, Johe K, Marsala S, Scadeng M, Kakinohana O, Navarro R, Santa M, Hefferan MP, Yaksh TL, Marsala M.

Cell Transplant. 2010;19(9):1103-22. doi: 10.3727/096368910X503406. Epub 2010 Apr 21.

PMID:
20412634
42.

Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival.

Nguyen QT, Olson ES, Aguilera TA, Jiang T, Scadeng M, Ellies LG, Tsien RY.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4317-22. doi: 10.1073/pnas.0910261107. Epub 2010 Feb 16.

43.

Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases.

Olson ES, Jiang T, Aguilera TA, Nguyen QT, Ellies LG, Scadeng M, Tsien RY.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4311-6. doi: 10.1073/pnas.0910283107. Epub 2010 Feb 16.

44.

Induction of in vivo synthetic lethal RNAi responses to treat glioblastoma.

Michiue H, Eguchi A, Scadeng M, Dowdy SF.

Cancer Biol Ther. 2009 Dec;8(23):2306-13. Epub 2009 Dec 7.

PMID:
19901546
45.

The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice.

Weidemann A, Kerdiles YM, Knaup KX, Rafie CA, Boutin AT, Stockmann C, Takeda N, Scadeng M, Shih AY, Haase VH, Simon MC, Kleinfeld D, Johnson RS.

J Clin Invest. 2009 Nov;119(11):3373-83. doi: 10.1172/JCI39378. Epub 2009 Oct 5.

46.

Effect of proton pump inhibition on the gastric volume: assessed by magnetic resonance imaging.

Babaei A, Bhargava V, Aalam S, Scadeng M, Mittal RK.

Aliment Pharmacol Ther. 2009 Apr 15;29(8):863-70. doi: 10.1111/j.1365-2036.2009.03947.x. Epub 2009 Jan 24.

47.

Development of a novel mouse glioma model using lentiviral vectors.

Marumoto T, Tashiro A, Friedmann-Morvinski D, Scadeng M, Soda Y, Gage FH, Verma IM.

Nat Med. 2009 Jan;15(1):110-6. doi: 10.1038/nm.1863. Epub 2009 Jan 4.

48.

Development of diabesity in mice with neuronal deletion of Shp2 tyrosine phosphatase.

Krajewska M, Banares S, Zhang EE, Huang X, Scadeng M, Jhala US, Feng GS, Krajewski S.

Am J Pathol. 2008 May;172(5):1312-24. doi: 10.2353/ajpath.2008.070594. Epub 2008 Apr 10.

49.

Doxycycline treatment prevents alveolar destruction in VEGF-deficient mouse lung.

Rossiter HB, Scadeng M, Tang K, Wagner PD, Breen EC.

J Cell Biochem. 2008 May 15;104(2):525-35. doi: 10.1002/jcb.21643.

PMID:
18181212
50.

JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity.

Solinas G, Vilcu C, Neels JG, Bandyopadhyay GK, Luo JL, Naugler W, Grivennikov S, Wynshaw-Boris A, Scadeng M, Olefsky JM, Karin M.

Cell Metab. 2007 Nov;6(5):386-97.

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