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Items: 1 to 50 of 156

1.

Analysis of relationship between oxidized phospholipid structure and interaction with the class B scavenger receptors.

Gao D, Sayre LM, Podrez EA.

Methods Mol Biol. 2015;1208:29-48. doi: 10.1007/978-1-4939-1441-8_3.

PMID:
25323497
2.

Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links.

Perry EA, Castellani RJ, Moreira PI, Nunomura A, Lui Q, Harris PL, Sayre LM, Szweda PA, Szweda LI, Zhu X, Smith MA, Perry G.

Free Radic Res. 2013 Jul;47(6-7):507-10. doi: 10.3109/10715762.2013.794265. Epub 2013 May 10.

3.

Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover.

Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PLR, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G.

Free Radic Biol Med. 2012 Feb 1;52(3):699-704. doi: 10.1016/j.freeradbiomed.2011.11.004. Epub 2011 Nov 12.

4.

Lipid peroxidation modification of protein generates Nepsilon-(4-oxononanoyl)lysine as a pro-inflammatory ligand.

Shibata T, Shimozu Y, Wakita C, Shibata N, Kobayashi M, Machida S, Kato R, Itabe H, Zhu X, Sayre LM, Uchida K.

J Biol Chem. 2011 Jun 3;286(22):19943-57. doi: 10.1074/jbc.M110.187047. Epub 2011 Apr 6.

5.

A mass spectrometric analysis of 4-hydroxy-2-(E)-nonenal modification of cytochrome c.

Tang X, Sayre LM, Tochtrop GP.

J Mass Spectrom. 2011 Mar;46(3):290-7. doi: 10.1002/jms.1890.

6.

Structural and enzyme activity studies demonstrate that aryl substituted 2,3-butadienamine analogs inactivate Arthrobacter globiformis amine oxidase (AGAO) by chemical derivatization of the 2,4,5-trihydroxyphenylalanine quinone (TPQ) cofactor.

Ernberg K, Zhong B, Ko K, Miller L, Nguyen YH, Sayre LM, Guss JM, Lee I.

Biochim Biophys Acta. 2011 May;1814(5):638-46. doi: 10.1016/j.bbapap.2010.12.016. Epub 2011 Jan 6.

PMID:
21215824
7.

Mass spectrometric evidence for the existence of distinct modifications of different proteins by 2(E),4(E)-decadienal.

Zhu X, Tang X, Zhang J, Tochtrop GP, Anderson VE, Sayre LM.

Chem Res Toxicol. 2010 Mar 15;23(3):467-73. doi: 10.1021/tx900379a.

8.

Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease.

Moreira PI, Sayre LM, Zhu X, Nunomura A, Smith MA, Perry G.

Methods Mol Biol. 2010;610:419-34. doi: 10.1007/978-1-60327-029-8_25.

9.

Structural basis for the recognition of oxidized phospholipids in oxidized low density lipoproteins by class B scavenger receptors CD36 and SR-BI.

Gao D, Ashraf MZ, Kar NS, Lin D, Sayre LM, Podrez EA.

J Biol Chem. 2010 Feb 12;285(7):4447-54. doi: 10.1074/jbc.M109.082800. Epub 2009 Dec 8.

10.

Catabolism of 4-hydroxyacids and 4-hydroxynonenal via 4-hydroxy-4-phosphoacyl-CoAs.

Zhang GF, Kombu RS, Kasumov T, Han Y, Sadhukhan S, Zhang J, Sayre LM, Ray D, Gibson KM, Anderson VA, Tochtrop GP, Brunengraber H.

J Biol Chem. 2009 Nov 27;284(48):33521-34. doi: 10.1074/jbc.M109.055665. Epub 2009 Sep 15.

11.

Mass spectrometric characterization of protein modification by the products of nonenzymatic oxidation of linoleic acid.

Zhu X, Tang X, Anderson VE, Sayre LM.

Chem Res Toxicol. 2009 Aug;22(8):1386-97. doi: 10.1021/tx9000072.

12.
13.

Covalent cross-linking of glutathione and carnosine to proteins by 4-oxo-2-nonenal.

Zhu X, Gallogly MM, Mieyal JJ, Anderson VE, Sayre LM.

Chem Res Toxicol. 2009 Jun;22(6):1050-9. doi: 10.1021/tx9000144.

14.

The essential role of ERK in 4-oxo-2-nonenal-mediated cytotoxicity in SH-SY5Y human neuroblastoma cells.

Lee HP, Zhu X, Zhu X, Skidmore SC, Perry G, Sayre LM, Smith MA, Lee HG.

J Neurochem. 2009 Mar;108(6):1434-41. doi: 10.1111/j.1471-4159.2009.05883.x. Epub 2009 Jan 13.

15.
16.

Protein N-acylation: H2O2-mediated covalent modification of protein by lipid peroxidation-derived saturated aldehydes.

Ishino K, Shibata T, Ishii T, Liu YT, Toyokuni S, Zhu X, Sayre LM, Uchida K.

Chem Res Toxicol. 2008 Jun;21(6):1261-70. doi: 10.1021/tx800080x. Epub 2008 May 31.

PMID:
18512967
17.

Oxidations of N-(3-indoleethyl) cyclic aliphatic amines by horseradish peroxidase: the indole ring binds to the enzyme and mediates electron-transfer amine oxidation.

Ling KQ, Li WS, Sayre LM.

J Am Chem Soc. 2008 Jan 23;130(3):933-44. doi: 10.1021/ja075905s. Epub 2007 Dec 29.

PMID:
18163622
18.

Oxidative stress and neurotoxicity.

Sayre LM, Perry G, Smith MA.

Chem Res Toxicol. 2008 Jan;21(1):172-88. Epub 2007 Dec 4. Review.

PMID:
18052107
20.
21.
23.

Highly potent 3-pyrroline mechanism-based inhibitors of bovine plasma amine oxidase and mass spectrometric confirmation of cofactor derivatization.

Zhang Y, Ran C, Zhou G, Sayre LM.

Bioorg Med Chem. 2007 Feb 15;15(4):1868-77. Epub 2006 Nov 16.

PMID:
17150363
24.

Protein adducts generated from products of lipid oxidation: focus on HNE and one.

Sayre LM, Lin D, Yuan Q, Zhu X, Tang X.

Drug Metab Rev. 2006;38(4):651-75. Review.

PMID:
17145694
25.

Acrolein generation stimulates hypercontraction in isolated human blood vessels.

Conklin DJ, Bhatnagar A, Cowley HR, Johnson GH, Wiechmann RJ, Sayre LM, Trent MB, Boor PJ.

Toxicol Appl Pharmacol. 2006 Dec 15;217(3):277-88. Epub 2006 Sep 29.

26.
27.

Detection of dideoxyosone intermediates of glycation using a monoclonal antibody: characterization of major epitope structures.

Puttaiah S, Zhang Y, Pilch HA, Pfahler C, Oya-Ito T, Sayre LM, Nagaraj RH.

Arch Biochem Biophys. 2006 Feb 15;446(2):186-96. Epub 2005 Dec 27.

PMID:
16406213
28.

Inactivation of bovine plasma amine oxidase by haloallylamines.

Kim J, Zhang Y, Ran C, Sayre LM.

Bioorg Med Chem. 2006 Mar 1;14(5):1444-53. Epub 2005 Nov 2.

PMID:
16266805
29.

Metal ions and oxidative protein modification in neurological disease.

Sayre LM, Moreira PI, Smith MA, Perry G.

Ann Ist Super Sanita. 2005;41(2):143-64. Review.

30.

4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal.

Lin D, Lee HG, Liu Q, Perry G, Smith MA, Sayre LM.

Chem Res Toxicol. 2005 Aug;18(8):1219-31.

PMID:
16097795
31.

Horseradish peroxidase-mediated aerobic and anaerobic oxidations of 3-alkylindoles.

Ling KQ, Sayre LM.

Bioorg Med Chem. 2005 May 16;13(10):3543-51.

PMID:
15848767
32.
33.

Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations.

Liu Q, Smith MA, Avilá J, DeBernardis J, Kansal M, Takeda A, Zhu X, Nunomura A, Honda K, Moreira PI, Oliveira CR, Santos MS, Shimohama S, Aliev G, de la Torre J, Ghanbari HA, Siedlak SL, Harris PL, Sayre LM, Perry G.

Free Radic Biol Med. 2005 Mar 15;38(6):746-54.

PMID:
15721985
34.

Ligand dependence in the copper-catalyzed oxidation of hydroquinones.

Mandal S, Kazmi NH, Sayre LM.

Arch Biochem Biophys. 2005 Mar 1;435(1):21-31.

PMID:
15680903
35.

1,5-diamino-2-pentyne is both a substrate and inactivator of plant copper amine oxidases.

Lamplot Z, Sebela M, Malon M, Lenobel R, Lemr K, Havlis J, Pec P, Qiao C, Sayre LM.

Eur J Biochem. 2004 Dec;271(23-24):4696-708.

36.

Inhibition of murine N1-acetylated polyamine oxidase by an acetylenic amine and the allenic amine, MDL 72527.

Wu T, Ling KQ, Sayre LM, McIntire WS.

Biochem Biophys Res Commun. 2005 Jan 14;326(2):483-90.

PMID:
15582603
37.

Differential inhibition of six copper amine oxidases by a family of 4-(aryloxy)-2-butynamines: evidence for a new mode of inactivation.

O'Connell KM, Langley DB, Shepard EM, Duff AP, Jeon HB, Sun G, Freeman HC, Guss JM, Sayre LM, Dooley DM.

Biochemistry. 2004 Aug 31;43(34):10965-78.

PMID:
15323556
38.

Selective inhibition of bovine plasma amine oxidase by homopropargylamine, a new inactivator motif.

Qiao C, Jeon HB, Sayre LM.

J Am Chem Soc. 2004 Jun 30;126(25):8038-45.

PMID:
15212554
39.

In situ localization of nonenzymatic peroxidase-like activity of tissue-bound transition metals.

Sayre LM, Harris PL, Perry G, Smith MA.

Curr Protoc Toxicol. 2004 Jun;Chapter 17:Unit17.4. doi: 10.1002/0471140856.tx1704s20.

PMID:
23045100
40.
41.

Cyanide as a copper and quinone-directed inhibitor of amine oxidases from pea seedlings ( Pisum sativum) and Arthrobacter globiformis: evidence for both copper coordination and cyanohydrin derivatization of the quinone cofactor.

Shepard EM, Juda GA, Ling KQ, Sayre LM, Dooley DM.

J Biol Inorg Chem. 2004 Apr;9(3):256-68. Epub 2004 Feb 19. Erratum in: J Biol Inorg Chem. 2004 Jun;9(4):507.

PMID:
14986071
42.

Model studies on the metal-catalyzed protein oxidation: structure of a possible His-Lys cross-link.

Liu Y, Sun G, David A, Sayre LM.

Chem Res Toxicol. 2004 Jan;17(1):110-8.

PMID:
14727925
43.

Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta.

Atwood CS, Perry G, Zeng H, Kato Y, Jones WD, Ling KQ, Huang X, Moir RD, Wang D, Sayre LM, Smith MA, Chen SG, Bush AI.

Biochemistry. 2004 Jan 20;43(2):560-8.

PMID:
14717612
44.
45.

Inhibition of bovine plasma amine oxidase by 1,4-diamino-2-butenes and -2-butynes.

Jeon HB, Lee Y, Qiao C, Huang H, Sayre LM.

Bioorg Med Chem. 2003 Oct 15;11(21):4631-41.

PMID:
14527560
46.

Hydroxynonenal, toxic carbonyls, and Alzheimer disease.

Liu Q, Raina AK, Smith MA, Sayre LM, Perry G.

Mol Aspects Med. 2003 Aug-Oct;24(4-5):305-13. Review.

PMID:
12893008
47.
48.

Highly potent propargylamine and allylamine inhibitors of bovine plasma amine oxidase.

Jeon HB, Sayre LM.

Biochem Biophys Res Commun. 2003 May 16;304(4):788-94.

PMID:
12727226
49.

Model studies on protein side chain modification by 4-oxo-2-nonenal.

Zhang WH, Liu J, Xu G, Yuan Q, Sayre LM.

Chem Res Toxicol. 2003 Apr;16(4):512-23.

PMID:
12703968
50.

Inactivation of bovine plasma amine oxidase by 4-aryloxy-2-butynamines and related analogs.

Jeon HB, Sun G, Sayre LM.

Biochim Biophys Acta. 2003 Apr 11;1647(1-2):343-54.

PMID:
12686156

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