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Items: 1 to 50 of 95

1.

Exposure to lipopolysaccharide (LPS) reduces contractile response of small airways from GSTCD-/- mice.

Liu B, Henry AP, Azimi S, Miller S, Lee FK, Lee JC, Probert K, Kotlikoff MI, Sayers I, Hall IP.

PLoS One. 2019 Sep 12;14(9):e0221899. doi: 10.1371/journal.pone.0221899. eCollection 2019.

2.

Defining a role for lung function associated gene GSTCD in cell homeostasis.

Henry AP, Probert K, Stewart CE, Thakker D, Bhaker S, Azimi S, Hall IP, Sayers I.

Respir Res. 2019 Aug 1;20(1):172. doi: 10.1186/s12931-019-1146-3.

3.

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Shrine N, Guyatt AL, Erzurumluoglu AM, Jackson VE, Hobbs BD, Melbourne CA, Batini C, Fawcett KA, Song K, Sakornsakolpat P, Li X, Boxall R, Reeve NF, Obeidat M, Zhao JH, Wielscher M; Understanding Society Scientific Group, Weiss S, Kentistou KA, Cook JP, Sun BB, Zhou J, Hui J, Karrasch S, Imboden M, Harris SE, Marten J, Enroth S, Kerr SM, Surakka I, Vitart V, Lehtimäki T, Allen RJ, Bakke PS, Beaty TH, Bleecker ER, Bossé Y, Brandsma CA, Chen Z, Crapo JD, Danesh J, DeMeo DL, Dudbridge F, Ewert R, Gieger C, Gulsvik A, Hansell AL, Hao K, Hoffman JD, Hokanson JE, Homuth G, Joshi PK, Joubert P, Langenberg C, Li X, Li L, Lin K, Lind L, Locantore N, Luan J, Mahajan A, Maranville JC, Murray A, Nickle DC, Packer R, Parker MM, Paynton ML, Porteous DJ, Prokopenko D, Qiao D, Rawal R, Runz H, Sayers I, Sin DD, Smith BH, Artigas MS, Sparrow D, Tal-Singer R, Timmers PRHJ, Van den Berge M, Whittaker JC, Woodruff PG, Yerges-Armstrong LM, Troyanskaya OG, Raitakari OT, Kähönen M, Polašek O, Gyllensten U, Rudan I, Deary IJ, Probst-Hensch NM, Schulz H, James AL, Wilson JF, Stubbe B, Zeggini E, Jarvelin MR, Wareham N, Silverman EK, Hayward C, Morris AP, Butterworth AS, Scott RA, Walters RG, Meyers DA, Cho MH, Strachan DP, Hall IP, Tobin MD, Wain LV.

Nat Genet. 2019 Jun;51(6):1067. doi: 10.1038/s41588-019-0438-3.

PMID:
31110354
4.

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Shrine N, Guyatt AL, Erzurumluoglu AM, Jackson VE, Hobbs BD, Melbourne CA, Batini C, Fawcett KA, Song K, Sakornsakolpat P, Li X, Boxall R, Reeve NF, Obeidat M, Zhao JH, Wielscher M, Weiss S, Kentistou KA, Cook JP, Sun BB, Zhou J, Hui J, Karrasch S, Imboden M, Harris SE, Marten J, Enroth S, Kerr SM, Surakka I, Vitart V, Lehtimäki T, Allen RJ, Bakke PS, Beaty TH, Bleecker ER, Bossé Y, Brandsma CA, Chen Z, Crapo JD, Danesh J, DeMeo DL, Dudbridge F, Ewert R, Gieger C, Gulsvik A, Hansell AL, Hao K, Hoffman JD, Hokanson JE, Homuth G, Joshi PK, Joubert P, Langenberg C, Li X, Li L, Lin K, Lind L, Locantore N, Luan J, Mahajan A, Maranville JC, Murray A, Nickle DC, Packer R, Parker MM, Paynton ML, Porteous DJ, Prokopenko D, Qiao D, Rawal R, Runz H, Sayers I, Sin DD, Smith BH, Soler Artigas M, Sparrow D, Tal-Singer R, Timmers PRHJ, Van den Berge M, Whittaker JC, Woodruff PG, Yerges-Armstrong LM, Troyanskaya OG, Raitakari OT, Kähönen M, Polašek O, Gyllensten U, Rudan I, Deary IJ, Probst-Hensch NM, Schulz H, James AL, Wilson JF, Stubbe B, Zeggini E, Jarvelin MR, Wareham N, Silverman EK, Hayward C, Morris AP, Butterworth AS, Scott RA, Walters RG, Meyers DA, Cho MH, Strachan DP, Hall IP, Tobin MD, Wain LV; Understanding Society Scientific Group.

Nat Genet. 2019 Mar;51(3):481-493. doi: 10.1038/s41588-018-0321-7. Epub 2019 Feb 25. Erratum in: Nat Genet. 2019 Jun;51(6):1067.

5.

Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

Shrine N, Portelli MA, John C, Soler Artigas M, Bennett N, Hall R, Lewis J, Henry AP, Billington CK, Ahmad A, Packer RJ, Shaw D, Pogson ZEK, Fogarty A, McKeever TM, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Djukanovic R, Hankinson J, Niven R, Simpson A, Chung KF, Sterk PJ, Blakey JD, Adcock IM, Hu S, Guo Y, Obeidat M, Sin DD, van den Berge M, Nickle DC, Bossé Y, Tobin MD, Hall IP, Brightling CE, Wain LV, Sayers I.

Lancet Respir Med. 2019 Jan;7(1):20-34. doi: 10.1016/S2213-2600(18)30389-8. Epub 2018 Dec 11.

6.

Genetic risk factors for the development of pulmonary disease identified by genome-wide association.

Hall R, Hall IP, Sayers I.

Respirology. 2019 Mar;24(3):204-214. doi: 10.1111/resp.13436. Epub 2018 Nov 13. Review.

7.

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.

Allen RJ, Porte J, Braybrooke R, Flores C, Fingerlin TE, Oldham JM, Guillen-Guio B, Ma SF, Okamoto T, John AE, Obeidat M, Yang IV, Henry A, Hubbard RB, Navaratnam V, Saini G, Thompson N, Booth HL, Hart SP, Hill MR, Hirani N, Maher TM, McAnulty RJ, Millar AB, Molyneaux PL, Parfrey H, Rassl DM, Whyte MKB, Fahy WA, Marshall RP, Oballa E, Bossé Y, Nickle DC, Sin DD, Timens W, Shrine N, Sayers I, Hall IP, Noth I, Schwartz DA, Tobin MD, Wain LV, Jenkins RG.

Lancet Respir Med. 2017 Nov;5(11):869-880. doi: 10.1016/S2213-2600(17)30387-9. Epub 2017 Oct 20.

8.

Defining the inflammatory signature of human lung explant tissue in the presence and absence of glucocorticoid.

Rimington TL, Hodge E, Billington CK, Bhaker S, K C B, Kilty I, Jelinsky S, Hall IP, Sayers I.

F1000Res. 2017 Apr 11;6:460. doi: 10.12688/f1000research.10961.1. eCollection 2017.

9.

Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways.

Kheirallah AK, de Moor CH, Faiz A, Sayers I, Hall IP.

BMC Genomics. 2017 Mar 23;18(1):248. doi: 10.1186/s12864-017-3628-3.

10.

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

Wain LV, Shrine N, Artigas MS, Erzurumluoglu AM, Noyvert B, Bossini-Castillo L, Obeidat M, Henry AP, Portelli MA, Hall RJ, Billington CK, Rimington TL, Fenech AG, John C, Blake T, Jackson VE, Allen RJ, Prins BP; Understanding Society Scientific Group, Campbell A, Porteous DJ, Jarvelin MR, Wielscher M, James AL, Hui J, Wareham NJ, Zhao JH, Wilson JF, Joshi PK, Stubbe B, Rawal R, Schulz H, Imboden M, Probst-Hensch NM, Karrasch S, Gieger C, Deary IJ, Harris SE, Marten J, Rudan I, Enroth S, Gyllensten U, Kerr SM, Polasek O, Kähönen M, Surakka I, Vitart V, Hayward C, Lehtimäki T, Raitakari OT, Evans DM, Henderson AJ, Pennell CE, Wang CA, Sly PD, Wan ES, Busch R, Hobbs BD, Litonjua AA, Sparrow DW, Gulsvik A, Bakke PS, Crapo JD, Beaty TH, Hansel NN, Mathias RA, Ruczinski I, Barnes KC, Bossé Y, Joubert P, van den Berge M, Brandsma CA, Paré PD, Sin DD, Nickle DC, Hao K, Gottesman O, Dewey FE, Bruse SE, Carey DJ, Kirchner HL; Geisinger-Regeneron DiscovEHR Collaboration, Jonsson S, Thorleifsson G, Jonsdottir I, Gislason T, Stefansson K, Schurmann C, Nadkarni G, Bottinger EP, Loos RJ, Walters RG, Chen Z, Millwood IY, Vaucher J, Kurmi OP, Li L, Hansell AL, Brightling C, Zeggini E, Cho MH, Silverman EK, Sayers I, Trynka G, Morris AP, Strachan DP, Hall IP, Tobin MD.

Nat Genet. 2017 Mar;49(3):416-425. doi: 10.1038/ng.3787. Epub 2017 Feb 6.

11.

Targeted Sequencing of Lung Function Loci in Chronic Obstructive Pulmonary Disease Cases and Controls.

Artigas MS, Wain LV, Shrine N, McKeever TM; UK BiLEVE, Sayers I, Hall IP, Tobin MD.

PLoS One. 2017 Jan 23;12(1):e0170222. doi: 10.1371/journal.pone.0170222. eCollection 2017.

12.

The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production In Vitro.

Miller S, Henry AP, Hodge E, Kheirallah AK, Billington CK, Rimington TL, Bhaker SK, Obeidat M, Melén E, Merid SK, Swan C, Gowland C, Nelson CP, Stewart CE, Bolton CE, Kilty I, Malarstig A, Parker SG, Moffatt MF, Wardlaw AJ, Hall IP, Sayers I.

PLoS One. 2016 Oct 18;11(10):e0164041. doi: 10.1371/journal.pone.0164041. eCollection 2016.

13.

The differential effects of azithromycin on the airway epithelium in vitro and in vivo.

Slater M, Torr E, Harrison T, Forrester D, Knox A, Shaw D, Sayers I.

Physiol Rep. 2016 Sep;4(18). pii: e12960.

14.

Airway and peripheral urokinase plasminogen activator receptor is elevated in asthma, and identifies a severe, nonatopic subset of patients.

Portelli MA, Moseley C, Stewart CE, Postma DS, Howarth P, Warner JA, Holloway JW, Koppelman GH, Brightling C, Sayers I.

Allergy. 2017 Mar;72(3):473-482. doi: 10.1111/all.13046. Epub 2016 Oct 5.

PMID:
27624865
15.

Expression of polycomb protein BMI-1 maintains the plasticity of basal bronchial epithelial cells.

Torr E, Heath M, Mee M, Shaw D, Sharp TV, Sayers I.

Physiol Rep. 2016 Aug;4(16). pii: e12847. doi: 10.14814/phy2.12847.

16.

Genes associated with polymorphic variants predicting lung function are differentially expressed during human lung development.

Miller S, Melén E, Merid SK, Hall IP, Sayers I.

Respir Res. 2016 Jul 29;17(1):95. doi: 10.1186/s12931-016-0410-z.

17.

Chemoradiotherapy with Brachytherapy or Electron Therapy Boost for Locally Advanced Squamous Cell Carcinoma of the Anus-Reducing the Colostomy Rate.

Kent C, Bessell EM, Scholefield JH, Chappell S, Marsh L, Mills J, Sayers I.

J Gastrointest Cancer. 2017 Mar;48(1):1-7. doi: 10.1007/s12029-016-9850-4.

18.

Traditional and emerging indicators of cardiovascular risk in chronic obstructive pulmonary disease.

John M, McKeever TM, Haddad MA, Hall IP, Sayers I, Cockcroft JR, Bolton CE.

Chron Respir Dis. 2016 Aug;13(3):247-55. doi: 10.1177/1479972316636995. Epub 2016 Mar 10.

19.

Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12.

Jackson VE, Ntalla I, Sayers I, Morris R, Whincup P, Casas JP, Amuzu A, Choi M, Dale C, Kumari M, Engmann J, Kalsheker N, Chappell S, Guetta-Baranes T, McKeever TM, Palmer CN, Tavendale R, Holloway JW, Sayer AA, Dennison EM, Cooper C, Bafadhel M, Barker B, Brightling C, Bolton CE, John ME, Parker SG, Moffat MF, Wardlaw AJ, Connolly MJ, Porteous DJ, Smith BH, Padmanabhan S, Hocking L, Stirrups KE, Deloukas P, Strachan DP, Hall IP, Tobin MD, Wain LV.

Thorax. 2016 Jun;71(6):501-9. doi: 10.1136/thoraxjnl-2015-207876. Epub 2016 Feb 25.

20.

Translating Lung Function Genome-Wide Association Study (GWAS) Findings: New Insights for Lung Biology.

Kheirallah AK, Miller S, Hall IP, Sayers I.

Adv Genet. 2016;93:57-145. doi: 10.1016/bs.adgen.2015.12.002. Epub 2016 Feb 9. Review.

PMID:
26915270
21.

Urokinase plasminogen activator receptor polymorphisms and airway remodelling in asthma.

Ierodiakonou D, Portelli MA, Postma DS, Koppelman GH, Gerritsen J, Ten Hacken NH, Timens W, Boezen HM, Vonk JM, Sayers I.

Eur Respir J. 2016 May;47(5):1568-71. doi: 10.1183/13993003.01571-2015. Epub 2016 Feb 11. No abstract available.

22.

The challenge of measuring IL-33 in serum using commercial ELISA: lessons from asthma.

Ketelaar ME, Nawijn MC, Shaw DE, Koppelman GH, Sayers I.

Clin Exp Allergy. 2016 Jun;46(6):884-7. doi: 10.1111/cea.12718.

PMID:
26850082
23.

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation.

Soler Artigas M, Wain LV, Miller S, Kheirallah AK, Huffman JE, Ntalla I, Shrine N, Obeidat M, Trochet H, McArdle WL, Alves AC, Hui J, Zhao JH, Joshi PK, Teumer A, Albrecht E, Imboden M, Rawal R, Lopez LM, Marten J, Enroth S, Surakka I, Polasek O, Lyytikäinen LP, Granell R, Hysi PG, Flexeder C, Mahajan A, Beilby J, Bossé Y, Brandsma CA, Campbell H, Gieger C, Gläser S, González JR, Grallert H, Hammond CJ, Harris SE, Hartikainen AL, Heliövaara M, Henderson J, Hocking L, Horikoshi M, Hutri-Kähönen N, Ingelsson E, Johansson Å, Kemp JP, Kolcic I, Kumar A, Lind L, Melén E, Musk AW, Navarro P, Nickle DC, Padmanabhan S, Raitakari OT, Ried JS, Ripatti S, Schulz H, Scott RA, Sin DD, Starr JM; UK BiLEVE, Viñuela A, Völzke H, Wild SH, Wright AF, Zemunik T, Jarvis DL, Spector TD, Evans DM, Lehtimäki T, Vitart V, Kähönen M, Gyllensten U, Rudan I, Deary IJ, Karrasch S, Probst-Hensch NM, Heinrich J, Stubbe B, Wilson JF, Wareham NJ, James AL, Morris AP, Jarvelin MR, Hayward C, Sayers I, Strachan DP, Hall IP, Tobin MD.

Nat Commun. 2015 Dec 4;6:8658. doi: 10.1038/ncomms9658.

24.

Response.

Sayers I, Portelli MA, Siedlinski M.

FASEB J. 2015 Dec;29(12):4759. doi: 10.1096/fj.15-1201LTER. No abstract available. Erratum in: FASEB J. 2016 Jun;30(6):2451.

PMID:
26626708
25.

Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank.

Wain LV, Shrine N, Miller S, Jackson VE, Ntalla I, Soler Artigas M, Billington CK, Kheirallah AK, Allen R, Cook JP, Probert K, Obeidat M, Bossé Y, Hao K, Postma DS, Paré PD, Ramasamy A; UK Brain Expression Consortium (UKBEC), Mägi R, Mihailov E, Reinmaa E, Melén E, O'Connell J, Frangou E, Delaneau O; OxGSK Consortium, Freeman C, Petkova D, McCarthy M, Sayers I, Deloukas P, Hubbard R, Pavord I, Hansell AL, Thomson NC, Zeggini E, Morris AP, Marchini J, Strachan DP, Tobin MD, Hall IP.

Lancet Respir Med. 2015 Oct;3(10):769-81. doi: 10.1016/S2213-2600(15)00283-0. Epub 2015 Sep 27. Erratum in: Lancet Respir Med. 2016 Jan;4(1):e4. Erratum in: Lancet Respir Med. 2016 Jan;4(1):e4.

26.

Cigarette Smoke and the Induction of Urokinase Plasminogen Activator Receptor In Vivo: Selective Contribution of Isoforms to Bronchial Epithelial Phenotype.

Portelli MA, Stewart CE, Hall IP, Brightling CE, Sayers I.

Am J Respir Cell Mol Biol. 2015 Aug;53(2):174-83. doi: 10.1165/rcmb.2014-0296OC.

PMID:
25490122
27.

Impact of the introduction of weekly radiotherapy quality assurance meetings at one UK cancer centre.

Brammer CV, Pettit L, Allerton R, Churn M, Joseph M, Koh P, Sayers I, King M.

Br J Radiol. 2014 Nov;87(1043):20140422. doi: 10.1259/bjr.20140422. Epub 2014 Sep 24.

28.

Mouse protocadherin-1 gene expression is regulated by cigarette smoke exposure in vivo.

Koning H, van Oosterhout AJ, Brouwer U, den Boef LE, Gras R, Reinders-Luinge M, Brandsma CA, van der Toorn M, Hylkema MN, Willemse BW, Sayers I, Koppelman GH, Nawijn MC.

PLoS One. 2014 Jul 3;9(7):e98197. doi: 10.1371/journal.pone.0098197. eCollection 2014.

29.

Genome-wide association analysis identifies six new loci associated with forced vital capacity.

Loth DW, Soler Artigas M, Gharib SA, Wain LV, Franceschini N, Koch B, Pottinger TD, Smith AV, Duan Q, Oldmeadow C, Lee MK, Strachan DP, James AL, Huffman JE, Vitart V, Ramasamy A, Wareham NJ, Kaprio J, Wang XQ, Trochet H, Kähönen M, Flexeder C, Albrecht E, Lopez LM, de Jong K, Thyagarajan B, Alves AC, Enroth S, Omenaas E, Joshi PK, Fall T, Viñuela A, Launer LJ, Loehr LR, Fornage M, Li G, Wilk JB, Tang W, Manichaikul A, Lahousse L, Harris TB, North KE, Rudnicka AR, Hui J, Gu X, Lumley T, Wright AF, Hastie ND, Campbell S, Kumar R, Pin I, Scott RA, Pietiläinen KH, Surakka I, Liu Y, Holliday EG, Schulz H, Heinrich J, Davies G, Vonk JM, Wojczynski M, Pouta A, Johansson A, Wild SH, Ingelsson E, Rivadeneira F, Völzke H, Hysi PG, Eiriksdottir G, Morrison AC, Rotter JI, Gao W, Postma DS, White WB, Rich SS, Hofman A, Aspelund T, Couper D, Smith LJ, Psaty BM, Lohman K, Burchard EG, Uitterlinden AG, Garcia M, Joubert BR, McArdle WL, Musk AB, Hansel N, Heckbert SR, Zgaga L, van Meurs JB, Navarro P, Rudan I, Oh YM, Redline S, Jarvis DL, Zhao JH, Rantanen T, O'Connor GT, Ripatti S, Scott RJ, Karrasch S, Grallert H, Gaddis NC, Starr JM, Wijmenga C, Minster RL, Lederer DJ, Pekkanen J, Gyllensten U, Campbell H, Morris AP, Gläser S, Hammond CJ, Burkart KM, Beilby J, Kritchevsky SB, Gudnason V, Hancock DB, Williams OD, Polasek O, Zemunik T, Kolcic I, Petrini MF, Wjst M, Kim WJ, Porteous DJ, Scotland G, Smith BH, Viljanen A, Heliövaara M, Attia JR, Sayers I, Hampel R, Gieger C, Deary IJ, Boezen HM, Newman A, Jarvelin MR, Wilson JF, Lind L, Stricker BH, Teumer A, Spector TD, Melén E, Peters MJ, Lange LA, Barr RG, Bracke KR, Verhamme FM, Sung J, Hiemstra PS, Cassano PA, Sood A, Hayward C, Dupuis J, Hall IP, Brusselle GG, Tobin MD, London SJ.

Nat Genet. 2014 Jul;46(7):669-77. doi: 10.1038/ng.3011. Epub 2014 Jun 15.

30.

Clonally expanded human airway smooth muscle cells exhibit morphological and functional heterogeneity.

Singh SR, Billington CK, Sayers I, Hall IP.

Respir Res. 2014 May 3;15:57. doi: 10.1186/1465-9921-15-57.

31.

Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction.

Wain LV, Sayers I, Soler Artigas M, Portelli MA, Zeggini E, Obeidat M, Sin DD, Bossé Y, Nickle D, Brandsma CA, Malarstig A, Vangjeli C, Jelinsky SA, John S, Kilty I, McKeever T, Shrine NR, Cook JP, Patel S, Spector TD, Hollox EJ, Hall IP, Tobin MD.

PLoS Genet. 2014 May 1;10(5):e1004314. doi: 10.1371/journal.pgen.1004314. eCollection 2014 May.

32.

Genetic risk factors for the development of allergic disease identified by genome-wide association.

Portelli MA, Hodge E, Sayers I.

Clin Exp Allergy. 2015 Jan;45(1):21-31. doi: 10.1111/cea.12327. Review.

33.

Copy number variation of the beta-defensin genes in europeans: no supporting evidence for association with lung function, chronic obstructive pulmonary disease or asthma.

Wain LV, Odenthal-Hesse L, Abujaber R, Sayers I, Beardsmore C, Gaillard EA, Chappell S, Dogaru CM, McKeever T, Guetta-Baranes T, Kalsheker N, Kuehni CE, Hall IP, Tobin MD, Hollox EJ.

PLoS One. 2014 Jan 3;9(1):e84192. doi: 10.1371/journal.pone.0084192. eCollection 2014.

34.

The impact of azithromycin therapy on the airway microbiota in asthma.

Slater M, Rivett DW, Williams L, Martin M, Harrison T, Sayers I, Bruce KD, Shaw D.

Thorax. 2014 Jul;69(7):673-4. doi: 10.1136/thoraxjnl-2013-204517. Epub 2013 Nov 28. No abstract available.

35.

Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels.

Portelli MA, Siedlinski M, Stewart CE, Postma DS, Nieuwenhuis MA, Vonk JM, Nurnberg P, Altmuller J, Moffatt MF, Wardlaw AJ, Parker SG, Connolly MJ, Koppelman GH, Sayers I.

FASEB J. 2014 Feb;28(2):923-34. doi: 10.1096/fj.13-240879. Epub 2013 Nov 18.

36.

Defining the contribution of SNPs identified in asthma GWAS to clinical variables in asthmatic children.

Tulah AS, Holloway JW, Sayers I.

BMC Med Genet. 2013 Sep 25;14:100. doi: 10.1186/1471-2350-14-100.

37.

GSTCD and INTS12 regulation and expression in the human lung.

Obeidat M, Miller S, Probert K, Billington CK, Henry AP, Hodge E, Nelson CP, Stewart CE, Swan C, Wain LV, Soler Artigas M, Melén E, Ushey K, Hao K, Lamontagne M, Bossé Y, Postma DS, Tobin MD, Sayers I, Hall IP.

PLoS One. 2013 Sep 18;8(9):e74630. doi: 10.1371/journal.pone.0074630. eCollection 2013.

38.

HTR4 gene structure and altered expression in the developing lung.

Hodge E, Nelson CP, Miller S, Billington CK, Stewart CE, Swan C, Malarstig A, Henry AP, Gowland C, Melén E, Hall IP, Sayers I.

Respir Res. 2013 Jul 26;14:77. doi: 10.1186/1465-9921-14-77.

39.

IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction.

Barlow JL, Peel S, Fox J, Panova V, Hardman CS, Camelo A, Bucks C, Wu X, Kane CM, Neill DR, Flynn RJ, Sayers I, Hall IP, McKenzie AN.

J Allergy Clin Immunol. 2013 Oct;132(4):933-41. doi: 10.1016/j.jaci.2013.05.012. Epub 2013 Jun 27.

PMID:
23810766
40.

Effects of atopy and grass pollen season on histamine H₄ receptor expression in human leukocytes.

Hodge E, Chang WY, Selby KA, Hall IP, Sayers I.

Ann Allergy Asthma Immunol. 2013 Jul;111(1):38-44. doi: 10.1016/j.anai.2013.04.017. Epub 2013 May 31.

PMID:
23806458
41.

Urokinase receptor orchestrates the plasminogen system in airway epithelial cell function.

Stewart CE, Sayers I.

Lung. 2013 Apr;191(2):215-25. doi: 10.1007/s00408-013-9450-z. Epub 2013 Feb 14.

PMID:
23408042
42.

A tailored approach to asthma management: Arg(16) holds the key?

Sayers I.

Clin Sci (Lond). 2013 Apr;124(8):517-9. doi: 10.1042/CS20120640.

PMID:
23205695
43.

Leukotriene B4 receptor locus gene characterisation and association studies in asthma.

Tulah AS, Beghé B, Barton SJ, Holloway JW, Sayers I.

BMC Med Genet. 2012 Nov 20;13:110. doi: 10.1186/1471-2350-13-110.

44.

Genome-wide association study to identify genetic determinants of severe asthma.

Wan YI, Shrine NR, Soler Artigas M, Wain LV, Blakey JD, Moffatt MF, Bush A, Chung KF, Cookson WO, Strachan DP, Heaney L, Al-Momani BA, Mansur AH, Manney S, Thomson NC, Chaudhuri R, Brightling CE, Bafadhel M, Singapuri A, Niven R, Simpson A, Holloway JW, Howarth PH, Hui J, Musk AW, James AL; Australian Asthma Genetics Consortium, Brown MA, Baltic S, Ferreira MA, Thompson PJ, Tobin MD, Sayers I, Hall IP.

Thorax. 2012 Sep;67(9):762-8. Epub 2012 May 5.

45.

Genetic basis for personalized medicine in asthma.

Portelli M, Sayers I.

Expert Rev Respir Med. 2012 Apr;6(2):223-36. doi: 10.1586/ers.12.9. Review.

PMID:
22455494
46.

Evaluation of differentiated human bronchial epithelial cell culture systems for asthma research.

Stewart CE, Torr EE, Mohd Jamili NH, Bosquillon C, Sayers I.

J Allergy (Cairo). 2012;2012:943982. doi: 10.1155/2012/943982. Epub 2012 Jan 11.

47.

The role of ALOX5AP, LTA4H and LTB4R polymorphisms in determining baseline lung function and COPD susceptibility in UK smokers.

Tulah AS, Parker SG, Moffatt MF, Wardlaw AJ, Connolly MJ, Sayers I.

BMC Med Genet. 2011 Dec 29;12:173. doi: 10.1186/1471-2350-12-173.

48.

uPAR regulates bronchial epithelial repair in vitro and is elevated in asthmatic epithelium.

Stewart CE, Nijmeh HS, Brightling CE, Sayers I.

Thorax. 2012 Jun;67(6):477-87. doi: 10.1136/thoraxjnl-2011-200508. Epub 2011 Dec 3.

49.

Characterization of protocadherin-1 expression in primary bronchial epithelial cells: association with epithelial cell differentiation.

Koning H, Sayers I, Stewart CE, de Jong D, Ten Hacken NH, Postma DS, van Oosterhout AJ, Nawijn MC, Koppelman GH.

FASEB J. 2012 Jan;26(1):439-48. doi: 10.1096/fj.11-185207. Epub 2011 Oct 7.

PMID:
21982948
50.

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