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Items: 9

1.

The discovery of 4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1 ,5-a]-pyrimidine: a corticotropin-releasing factor (hCRF1) antagonist.

Gilligan PJ, Baldauf C, Cocuzza A, Chidester D, Zaczek R, Fitzgerald LW, McElroy J, Smith MA, Shen HS, Saye JA, Christ D, Trainor G, Robertson DW, Hartig P.

Bioorg Med Chem. 2000 Jan;8(1):181-9.

PMID:
10968277
2.

4-(1,3-Dimethoxyprop-2-ylamino)-2,7-dimethyl-8-(2, 4-dichlorophenyl)pyrazolo[1,5-a]-1,3,5-triazine: a potent, orally bioavailable CRF(1) receptor antagonist.

He L, Gilligan PJ, Zaczek R, Fitzgerald LW, McElroy J, Shen HS, Saye JA, Kalin NH, Shelton S, Christ D, Trainor G, Hartig P.

J Med Chem. 2000 Feb 10;43(3):449-56.

PMID:
10669572
3.

Expanded-spectrum nonnucleoside reverse transcriptase inhibitors inhibit clinically relevant mutant variants of human immunodeficiency virus type 1.

Corbett JW, Ko SS, Rodgers JD, Jeffrey S, Bacheler LT, Klabe RM, Diamond S, Lai CM, Rabel SR, Saye JA, Adams SP, Trainor GL, Anderson PS, Erickson-Viitanen SK.

Antimicrob Agents Chemother. 1999 Dec;43(12):2893-7.

4.

Two new potent neurotransmitter release enhancers, 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone and 10,10-bis(2-fluoro-4-pyridinylmethyl)-9(10H)-anthracenone: comparison to linopirdine.

Zaczek R, Chorvat RJ, Saye JA, Pierdomenico ME, Maciag CM, Logue AR, Fisher BN, Rominger DH, Earl RA.

J Pharmacol Exp Ther. 1998 May;285(2):724-30.

PMID:
9580619
5.

Angiotensin II receptors and angiotensin II receptor antagonists.

Timmermans PB, Wong PC, Chiu AT, Herblin WF, Benfield P, Carini DJ, Lee RJ, Wexler RR, Saye JA, Smith RD.

Pharmacol Rev. 1993 Jun;45(2):205-51. Review. No abstract available.

PMID:
8372104
6.

Localization of angiotensin peptide-forming enzymes of 3T3-F442A adipocytes.

Saye JA, Ragsdale NV, Carey RM, Peach MJ.

Am J Physiol. 1993 Jun;264(6 Pt 1):C1570-6.

PMID:
8333506
7.

Angiotensinogen gene expression in 3T3-L1 cells.

Saye JA, Cassis LA, Sturgill TW, Lynch KR, Peach MJ.

Am J Physiol. 1989 Feb;256(2 Pt 1):C448-51.

PMID:
2465693
8.

Role of endothelium in conversion of angiotensin I to angiotensin II in rabbit aorta.

Saye JA, Singer HA, Peach MJ.

Hypertension. 1984 Mar-Apr;6(2 Pt 1):216-21.

PMID:
6202632
9.

Effects of cytochrome P-450 inhibitors on endothelium-dependent relaxation in rabbit aorta.

Singer HA, Saye JA, Peach MJ.

Blood Vessels. 1984;21(5):223-30.

PMID:
6380624

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