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Items: 16

1.

Prompt treatment with uridine triacetate improves survival and reduces toxicity due to fluorouracil and capecitabine overdose or dihydropyrimidine dehydrogenase deficiency.

Garcia RAG, Saydoff JA, Bamat MK, von Borstel RW.

Toxicol Appl Pharmacol. 2018 Jun 13;353:67-73. doi: 10.1016/j.taap.2018.06.012. [Epub ahead of print]

PMID:
29908244
2.

Uridine prodrug improves memory in Tg2576 and TAPP mice and reduces pathological factors associated with Alzheimer's disease in related models.

Saydoff JA, Olariu A, Sheng J, Hu Z, Li Q, Garcia R, Pei J, Sun GY, von Borstel R.

J Alzheimers Dis. 2013;36(4):637-57. doi: 10.3233/JAD-130059.

PMID:
23648515
3.

Oral uridine pro-drug PN401 is neuroprotective in the R6/2 and N171-82Q mouse models of Huntington's disease.

Saydoff JA, Garcia RA, Browne SE, Liu L, Sheng J, Brenneman D, Hu Z, Cardin S, Gonzalez A, von Borstel RW, Gregorio J, Burr H, Beal MF.

Neurobiol Dis. 2006 Dec;24(3):455-65. Epub 2006 Sep 29.

PMID:
17011205
4.

Severe cytochrome c oxidase inhibition in vivo does not induce a pyrimidine deficiency; neuroprotective action of oral uridine prodrug PN401 requires supraphysiological levels of uridine.

Garcia RA, Liu L, Hu Z, Gonzalez A, von Borstel RW, Saydoff JA.

Brain Res. 2005 Dec 20;1066(1-2):164-71. Epub 2005 Dec 5.

PMID:
16330000
6.

No detectable analgesic effects in the formalin test even with one million bovine adrenal chromaffin cells.

Gulwadi AG, Hoane MR, Saydoff JA, Frydel BR, Lindner MD.

Pain. 2002 Sep;99(1-2):263-71.

PMID:
12237204
7.

The analgesic potential of intraventricular polymer-encapsulated adrenal chromaffin cells in a rodent model of chronic neuropathic pain.

Lindner MD, Francis JM, Plone MA, McDermott PE, Frydel BR, Emerich DF, Saydoff JA.

Exp Clin Psychopharmacol. 2000 Nov;8(4):524-38.

PMID:
11127424
8.

Numerous adrenal chromaffin cell preparations fail to produce analgesic effects in the formalin test or in tests of acute pain even with nicotine stimulation.

Lindner MD, Francis JM, McDermott PE, Bell WJ, Blaney TJ, Sherman SS, Saydoff JA.

Pain. 2000 Nov;88(2):177-88.

PMID:
11050373
9.

Intrathecal polymer-encapsulated bovine adrenal chromaffin cells fail to produce analgesic effects in the hotplate and formalin test.

Lindner MD, Francis JM, Saydoff JA.

Exp Neurol. 2000 Oct;165(2):370-83. Erratum in: Exp Neurol 2001 Jul;170(1):225.

PMID:
10993696
10.

Polymer-encapsulated PC-12 cells demonstrate high-affinity uptake of dopamine in vitro and 18F-Dopa uptake and metabolism after intracerebral implantation in nonhuman primates.

Subramanian T, Emerich DF, Bakay RA, Hoffman JM, Goodman MM, Shoup TM, Miller GW, Levey AI, Hubert GW, Batchelor S, Winn SR, Saydoff JA, Watts RL.

Cell Transplant. 1997 Sep-Oct;6(5):469-77.

PMID:
9331498
11.

Cellular delivery of human CNTF prevents motor and cognitive dysfunction in a rodent model of Huntington's disease.

Emerich DF, Cain CK, Greco C, Saydoff JA, Hu ZY, Liu H, Lindner MD.

Cell Transplant. 1997 May-Jun;6(3):249-66.

PMID:
9171158
12.

Neuroendocrine and cardiovascular effects of serotonin: selective role of brain angiotensin on vasopressin.

Saydoff JA, Rittenhouse PA, Carnes M, Armstrong J, Van De Kar LD, Brownfield MS.

Am J Physiol. 1996 Mar;270(3 Pt 1):E513-21.

PMID:
8638700
13.
14.

Studies on the role of K+, Cl- and Na+ ion permeabilities in the acetylcholine release enhancing effects of linopirdine (DuP 996) in rat cortical slices.

Maciag CM, Logue AR, Tinker WJ, Saydoff JA, Tam SW, Zaczek R.

J Pharmacol Exp Ther. 1994 Nov;271(2):891-7.

PMID:
7965810
15.
16.

Enhanced serotonergic transmission stimulates oxytocin secretion in conscious male rats.

Saydoff JA, Rittenhouse PA, van de Kar LD, Brownfield MS.

J Pharmacol Exp Ther. 1991 Apr;257(1):95-9.

PMID:
1850481

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