Sort by
Items per page

Send to

Choose Destination

Search results

Items: 50


Two kinesins drive anterograde neuropeptide transport.

Lim A, Rechtsteiner A, Saxton WM.

Mol Biol Cell. 2017 Nov 15;28(24):3542-3553. doi: 10.1091/mbc.E16-12-0820. Epub 2017 Sep 13.


A Mechanism for Cytoplasmic Streaming: Kinesin-Driven Alignment of Microtubules and Fast Fluid Flows.

Monteith CE, Brunner ME, Djagaeva I, Bielecki AM, Deutsch JM, Saxton WM.

Biophys J. 2016 May 10;110(9):2053-65. doi: 10.1016/j.bpj.2016.03.036.


Kinesin-1 tail autoregulation and microtubule-binding regions function in saltatory transport but not ooplasmic streaming.

Moua P, Fullerton D, Serbus LR, Warrior R, Saxton WM.

Development. 2016 Apr 1;143(7):1228. doi: 10.1242/dev.136747. No abstract available.


Three routes to suppression of the neurodegenerative phenotypes caused by kinesin heavy chain mutations.

Djagaeva I, Rose DJ, Lim A, Venter CE, Brendza KM, Moua P, Saxton WM.

Genetics. 2012 Sep;192(1):173-83. doi: 10.1534/genetics.112.140798. Epub 2012 Jun 19.


The axonal transport of mitochondria.

Saxton WM, Hollenbeck PJ.

J Cell Sci. 2012 May 1;125(Pt 9):2095-104. doi: 10.1242/jcs.053850. Epub 2012 May 22. Review.


Kinesin-1 tail autoregulation and microtubule-binding regions function in saltatory transport but not ooplasmic streaming.

Moua P, Fullerton D, Serbus LR, Warrior R, Saxton WM.

Development. 2011 Mar;138(6):1087-92. doi: 10.1242/dev.048645. Epub 2011 Feb 9. Erratum in: Development. 2016 Apr 1;143(7):1228.


Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides.

Barkus RV, Klyachko O, Horiuchi D, Dickson BJ, Saxton WM.

Mol Biol Cell. 2008 Jan;19(1):274-83. Epub 2007 Nov 7.


Control of a kinesin-cargo linkage mechanism by JNK pathway kinases.

Horiuchi D, Collins CA, Bhat P, Barkus RV, Diantonio A, Saxton WM.

Curr Biol. 2007 Aug 7;17(15):1313-7. Epub 2007 Jul 19.


Kinesin-5 acts as a brake in anaphase spindle elongation.

Saunders AM, Powers J, Strome S, Saxton WM.

Curr Biol. 2007 Jun 19;17(12):R453-4. No abstract available.


Kinesin-1 and Dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons.

Pilling AD, Horiuchi D, Lively CM, Saxton WM.

Mol Biol Cell. 2006 Apr;17(4):2057-68. Epub 2006 Feb 8.


The axonal transport of mitochondria.

Hollenbeck PJ, Saxton WM.

J Cell Sci. 2005 Dec 1;118(Pt 23):5411-9. Review.


Dynein and the actin cytoskeleton control kinesin-driven cytoplasmic streaming in Drosophila oocytes.

Serbus LR, Cha BJ, Theurkauf WE, Saxton WM.

Development. 2005 Aug;132(16):3743-52.


Abl tyrosine kinase and its substrate Ena/VASP have functional interactions with kinesin-1.

Martin M, Ahern-Djamali SM, Hoffmann FM, Saxton WM.

Mol Biol Cell. 2005 Sep;16(9):4225-30. Epub 2005 Jun 22.


Functional analysis of cytoplasmic dynein heavy chain in Caenorhabditis elegans with fast-acting temperature-sensitive mutations.

Schmidt DJ, Rose DJ, Saxton WM, Strome S.

Mol Biol Cell. 2005 Mar;16(3):1200-12. Epub 2004 Dec 22.


A standardized kinesin nomenclature.

Lawrence CJ, Dawe RK, Christie KR, Cleveland DW, Dawson SC, Endow SA, Goldstein LS, Goodson HV, Hirokawa N, Howard J, Malmberg RL, McIntosh JR, Miki H, Mitchison TJ, Okada Y, Reddy AS, Saxton WM, Schliwa M, Scholey JM, Vale RD, Walczak CE, Wordeman L.

J Cell Biol. 2004 Oct 11;167(1):19-22.


Loss of KLP-19 polar ejection force causes misorientation and missegregation of holocentric chromosomes.

Powers J, Rose DJ, Saunders A, Dunkelbarger S, Strome S, Saxton WM.

J Cell Biol. 2004 Sep 27;166(7):991-1001.


Microtubule-kinesin interface mutants reveal a site critical for communication.

Klumpp LM, Brendza KM, Gatial JE 3rd, Hoenger A, Saxton WM, Gilbert SP.

Biochemistry. 2004 Mar 16;43(10):2792-803.


A map of the interactome network of the metazoan C. elegans.

Li S, Armstrong CM, Bertin N, Ge H, Milstein S, Boxem M, Vidalain PO, Han JD, Chesneau A, Hao T, Goldberg DS, Li N, Martinez M, Rual JF, Lamesch P, Xu L, Tewari M, Wong SL, Zhang LV, Berriz GF, Jacotot L, Vaglio P, Reboul J, Hirozane-Kishikawa T, Li Q, Gabel HW, Elewa A, Baumgartner B, Rose DJ, Yu H, Bosak S, Sequerra R, Fraser A, Mango SE, Saxton WM, Strome S, Van Den Heuvel S, Piano F, Vandenhaute J, Sardet C, Gerstein M, Doucette-Stamm L, Gunsalus KC, Harper JW, Cusick ME, Roth FP, Hill DE, Vidal M.

Science. 2004 Jan 23;303(5657):540-3. Epub 2004 Jan 2.


KLP-18, a Klp2 kinesin, is required for assembly of acentrosomal meiotic spindles in Caenorhabditis elegans.

Segbert C, Barkus R, Powers J, Strome S, Saxton WM, Bossinger O.

Mol Biol Cell. 2003 Nov;14(11):4458-69. Epub 2003 Aug 22.


Posterior localization of dynein and dorsal-ventral axis formation depend on kinesin in Drosophila oocytes.

Brendza RP, Serbus LR, Saxton WM, Duffy JB.

Curr Biol. 2002 Sep 3;12(17):1541-5.


Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways.

Yager J, Richards S, Hekmat-Scafe DS, Hurd DD, Sundaresan V, Caprette DR, Saxton WM, Carlson JR, Stern M.

Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10445-50. Epub 2001 Aug 21.


Kinesins in the nervous system.

Martin MA, Hurd DD, Saxton WM.

Cell Mol Life Sci. 1999 Oct 15;56(3-4):200-16. Review.


A function for kinesin I in the posterior transport of oskar mRNA and Staufen protein.

Brendza RP, Serbus LR, Duffy JB, Saxton WM.

Science. 2000 Sep 22;289(5487):2120-2.


A kinesin mutation that uncouples motor domains and desensitizes the gamma-phosphate sensor.

Brendza KM, Sontag CA, Saxton WM, Gilbert SP.

J Biol Chem. 2000 Jul 21;275(29):22187-95.


Clonal tests of conventional kinesin function during cell proliferation and differentiation.

Brendza RP, Sheehan KB, Turner FR, Saxton WM.

Mol Biol Cell. 2000 Apr;11(4):1329-43.


Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport.

Martin M, Iyadurai SJ, Gassman A, Gindhart JG Jr, Hays TS, Saxton WM.

Mol Biol Cell. 1999 Nov;10(11):3717-28.


Lethal kinesin mutations reveal amino acids important for ATPase activation and structural coupling.

Brendza KM, Rose DJ, Gilbert SP, Saxton WM.

J Biol Chem. 1999 Oct 29;274(44):31506-14.


Intracellular motility: A special delivery service.

Saxton WM.

Curr Biol. 1999 Apr 22;9(8):R293-5. Review.


An essential bipolar mitotic motor.

Kashina AS, Scholey JM, Leszyk JD, Saxton WM.

Nature. 1996 Nov 21;384(6606):225. No abstract available.


A bipolar kinesin.

Kashina AS, Baskin RJ, Cole DG, Wedaman KP, Saxton WM, Scholey JM.

Nature. 1996 Jan 18;379(6562):270-2.


A "slow" homotetrameric kinesin-related motor protein purified from Drosophila embryos.

Cole DG, Saxton WM, Sheehan KB, Scholey JM.

J Biol Chem. 1994 Sep 16;269(37):22913-6.


Isolation and analysis of microtubule motor proteins.

Saxton WM.

Methods Cell Biol. 1994;44:279-88. Review.


Analyzing microtubule motors in real time.

Cohn SA, Saxton WM, Lye RJ, Scholey JM.

Methods Cell Biol. 1993;39:75-88. Review. No abstract available.


Effects of kinesin mutations on neuronal functions.

Gho M, McDonald K, Ganetzky B, Saxton WM.

Science. 1992 Oct 9;258(5080):313-6.


Evidence that the head of kinesin is sufficient for force generation and motility in vitro.

Yang JT, Saxton WM, Stewart RJ, Raff EC, Goldstein LS.

Science. 1990 Jul 6;249(4964):42-7.


Cell cycle-dependent changes in the dynamics of MAP 2 and MAP 4 in cultured cells.

Olmsted JB, Stemple DL, Saxton WM, Neighbors BW, McIntosh JR.

J Cell Biol. 1989 Jul;109(1):211-23.


Isolation and characterization of the gene encoding the heavy chain of Drosophila kinesin.

Yang JT, Saxton WM, Goldstein LS.

Proc Natl Acad Sci U S A. 1988 Mar;85(6):1864-8.


Drosophila kinesin: characterization of microtubule motility and ATPase.

Saxton WM, Porter ME, Cohn SA, Scholey JM, Raff EC, McIntosh JR.

Proc Natl Acad Sci U S A. 1988 Feb;85(4):1109-13.


Interzone microtubule behavior in late anaphase and telophase spindles.

Saxton WM, McIntosh JR.

J Cell Biol. 1987 Aug;105(2):875-86.


Dynamics of tubulin and calmodulin in the mammalian mitotic spindle.

McIntosh JR, Saxton WM, Stemple DL, Leslie RJ, Welsh MJ.

Ann N Y Acad Sci. 1986;466:566-79. No abstract available.


Tubulin dynamics in cultured mammalian cells.

Saxton WM, Stemple DL, Leslie RJ, Salmon ED, Zavortink M, McIntosh JR.

J Cell Biol. 1984 Dec;99(6):2175-86.


Assembly properties of fluorescein-labeled tubulin in vitro before and after fluorescence bleaching.

Leslie RJ, Saxton WM, Mitchison TJ, Neighbors B, Salmon ED, McIntosh JR.

J Cell Biol. 1984 Dec;99(6):2146-56.


Protease activity associated with loss of adhesiveness in mouse teratocarcinoma.

Meyer JT, Thompson PM, Behringer R, Steiner RC, Saxton WM, Oppenheimer SB.

Exp Cell Res. 1983 Jan;143(1):63-70.


Supplemental Content

Loading ...
Support Center