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Items: 1 to 50 of 125

1.

Viral shedding, and distribution of cytomegalovirus glycoprotein H (UL75), glycoprotein B (UL55), and glycoprotein N (UL73) genotypes in congenital cytomegalovirus infection.

Puhakka L, Pati S, Lappalainen M, Lönnqvist T, Niemensivu R, Lindahl P, Nieminen T, Seuri R, Nupponen I, Boppana S, Saxen H.

J Clin Virol. 2020 Feb 11;125:104287. doi: 10.1016/j.jcv.2020.104287. [Epub ahead of print]

2.

Antibiotics in early life associate with specific gut microbiota signatures in a prospective longitudinal infant cohort.

Korpela K, Salonen A, Saxen H, Nikkonen A, Peltola V, Jaakkola T, de Vos W, Kolho KL.

Pediatr Res. 2020 Jan 18. doi: 10.1038/s41390-020-0761-5. [Epub ahead of print]

PMID:
31954376
3.

Mycoplasma pneumoniae outbreak, Southeastern Finland, 2017-2018: molecular epidemiology and laboratory diagnostic lessons.

Kurkela S, Puolakkainen M, Hokynar K, Nieminen T, Saxen H, Mannonen L, Pietikäinen R.

Eur J Clin Microbiol Infect Dis. 2019 Oct;38(10):1867-1871. doi: 10.1007/s10096-019-03619-7. Epub 2019 Jul 1.

4.

Parachlamydia acanthamoebae Detected during a Pneumonia Outbreak in Southeastern Finland, in 2017⁻2018.

Hokynar K, Kurkela S, Nieminen T, Saxen H, Vesterinen EJ, Mannonen L, Pietikäinen R, Puolakkainen M.

Microorganisms. 2019 May 17;7(5). pii: E141. doi: 10.3390/microorganisms7050141.

5.

Novel DSP Spectrin 6 Region Variant Causes Neonatal Erythroderma, Failure to Thrive, Severe Herpes Simplex Infections and Brain Lesions.

Vakkilainen S, Puhakka L, Klemetti P, Heiskanen K, Seppänen M, Muona M, Posseme C, Duffy D, Väisänen T, Elomaa O, Palomäki M, Saxén H, Ranki A, Hannula-Jouppi K.

Acta Derm Venereol. 2019 Jul 1;99(9):789-796. doi: 10.2340/00015555-3203. Review.

6.

Mixed Integer Linear Programming Optimization of Gas Supply to a Local Market.

Mikolajková M, Saxén H, Pettersson F.

Ind Eng Chem Res. 2018 May 2;57(17):5951-5965. doi: 10.1021/acs.iecr.7b04197. Epub 2018 Mar 1.

7.

Outcome of children with ESBL-E. coli acute pyelonephritis treated with cephalosporins.

Vakkilainen S, Pätäri-Sampo A, Saxén H.

J Infect. 2018 Jul;77(1):75-81. doi: 10.1016/j.jinf.2018.03.009. Epub 2018 May 7. No abstract available.

PMID:
29746942
8.

The Burden of Congenital Cytomegalovirus Infection: A Prospective Cohort Study of 20 000 Infants in Finland.

Puhakka L, Lappalainen M, Lönnqvist T, Niemensivu R, Lindahl P, Nieminen T, Seuri R, Nupponen I, Pati S, Boppana S, Saxen H.

J Pediatric Infect Dis Soc. 2019 Jul 1;8(3):205-212. doi: 10.1093/jpids/piy027.

PMID:
29554325
9.

Congenital Cytomegalovirus: A European Expert Consensus Statement on Diagnosis and Management.

Luck SE, Wieringa JW, Blázquez-Gamero D, Henneke P, Schuster K, Butler K, Capretti MG, Cilleruelo MJ, Curtis N, Garofoli F, Heath P, Iosifidis E, Klein N, Lombardi G, Lyall H, Nieminen T, Pajkrt D, Papaevangelou V, Posfay-Barbe K, Puhakka L, Roilides E, Rojo P, Saavedra-Lozano J, Shah T, Sharland M, Saxen H, Vossen ACTM; ESPID Congenital CMV Group Meeting, Leipzig 2015.

Pediatr Infect Dis J. 2017 Dec;36(12):1205-1213. doi: 10.1097/INF.0000000000001763. Review. No abstract available.

PMID:
29140947
10.

Cerebral vasculitis and intracranial multiple aneurysms in a child with Lyme neuroborreliosis.

Kortela E, Hytönen J, Numminen J, Overmyer M, Saxen H, Oksi J.

JMM Case Rep. 2017 Apr 21;4(4):e005090. doi: 10.1099/jmmcr.0.005090. eCollection 2017 Apr.

11.

A detection dog for paediatric urinary tract infection caused by Escherichia coli.

Koskinen A, Koskinen H, Bäck L, Saxen H, Klockars T.

Infect Dis (Lond). 2017 Nov - Dec;49(11-12):874-877. doi: 10.1080/23744235.2017.1331466. Epub 2017 May 23. No abstract available.

PMID:
28535699
12.

Immunity against vaccine-preventable diseases in Finnish pediatric healthcare workers in 2015.

Koivisto K, Puhakka L, Lappalainen M, Blomqvist S, Saxén H, Nieminen T.

Vaccine. 2017 Mar 14;35(12):1608-1614. doi: 10.1016/j.vaccine.2017.02.018. Epub 2017 Feb 21.

PMID:
28233625
13.

Primary versus non-primary maternal cytomegalovirus infection as a cause of symptomatic congenital infection - register-based study from Finland.

Puhakka L, Renko M, Helminen M, Peltola V, Heiskanen-Kosma T, Lappalainen M, Surcel HM, Lönnqvist T, Saxen H.

Infect Dis (Lond). 2017 Jun;49(6):445-453. doi: 10.1080/23744235.2017.1279344. Epub 2017 Jan 24.

PMID:
28116961
14.

Off-label use of antimicrobials in neonates in a tertiary children's hospital.

Laine N, Kaukonen AM, Hoppu K, Airaksinen M, Saxen H.

Eur J Clin Pharmacol. 2017 May;73(5):609-614. doi: 10.1007/s00228-017-2200-z. Epub 2017 Jan 18.

PMID:
28101656
15.

Antimicrobial consumption in a tertiary children's hospital in Finland (2003-2013).

Laine N, Hoppu K, Airaksinen M, Saxen H.

Eur J Hosp Pharm. 2016 Sep;23(5):266-271. doi: 10.1136/ejhpharm-2015-000766. Epub 2016 Feb 11.

16.

Replacing risk-based early-onset-disease prevention with intrapartum group B streptococcus PCR testing.

Björklund V, Nieminen T, Ulander VM, Ahola T, Saxén H.

J Matern Fetal Neonatal Med. 2017 Feb;30(3):368-373. Epub 2016 Apr 25.

PMID:
27033364
17.

Decrease in seroprevalence for herpesviruses among pregnant women in Finland: cross-sectional study of three time points 1992, 2002 and 2012.

Puhakka L, Sarvikivi E, Lappalainen M, Surcel HM, Saxen H.

Infect Dis (Lond). 2016;48(5):406-10. doi: 10.3109/23744235.2015.1123290. Epub 2015 Dec 14.

PMID:
26654892
18.

Evaluation of Antimicrobial Therapy of Blood Culture Positive Healthcare-Associated Infections in Children.

Laine N, Vaara M, Anttila VJ, Hoppu K, Laaksonen R, Airaksinen M, Saxen H.

PLoS One. 2015 Nov 5;10(11):e0141555. doi: 10.1371/journal.pone.0141555. eCollection 2015.

19.

Invasive Group A Streptococcal Infections in Children: A Nationwide Survey in Finland.

Tapiainen T, Launonen S, Renko M, Saxen H, Salo E, Korppi M, Kainulainen L, Heiskanen-Kosma T, Lindholm L, Vuopio J, Huotari T, Rusanen J, Uhari M.

Pediatr Infect Dis J. 2016 Feb;35(2):123-8. doi: 10.1097/INF.0000000000000945.

PMID:
26440814
20.

Antibiotic exposure in infancy and risk of being overweight in the first 24 months of life.

Saari A, Virta LJ, Sankilampi U, Dunkel L, Saxen H.

Pediatrics. 2015 Apr;135(4):617-26. doi: 10.1542/peds.2014-3407.

21.

[Invasive community-acquired infections in children].

Jenu S, Simons L, Pätäri-Sampo A, Toropainen M, Saxén H.

Duodecim. 2014;130(14):1445-51. Finnish.

PMID:
25158584
22.

First dose in neonates: are juvenile mice, adults and in vitro-in silico data predictive of neonatal pharmacokinetics of fluconazole.

Zhao W, Le Guellec C, Benjamin DK Jr, Hope WW, Bourgeois T, Watt KM, van den Anker JN, Matrot B, Saxen H, Hoppu K, Manzoni P, Jacqz-Aigrain E.

Clin Pharmacokinet. 2014 Nov;53(11):1005-18. doi: 10.1007/s40262-014-0169-7.

23.

Infant botulism with prolonged faecal excretion of botulinum neurotoxin and Clostridium botulinum for 7 months.

Derman Y, Korkeala H, Salo E, Lönnqvist T, Saxen H, Lindström M.

Epidemiol Infect. 2014 Feb;142(2):335-9. doi: 10.1017/S0950268813001258. Epub 2013 May 21.

PMID:
23688392
24.

Cultural bias in the AAP's 2012 Technical Report and Policy Statement on male circumcision.

Frisch M, Aigrain Y, Barauskas V, Bjarnason R, Boddy SA, Czauderna P, de Gier RP, de Jong TP, Fasching G, Fetter W, Gahr M, Graugaard C, Greisen G, Gunnarsdottir A, Hartmann W, Havranek P, Hitchcock R, Huddart S, Janson S, Jaszczak P, Kupferschmid C, Lahdes-Vasama T, Lindahl H, MacDonald N, Markestad T, Märtson M, Nordhov SM, Pälve H, Petersons A, Quinn F, Qvist N, Rosmundsson T, Saxen H, Söder O, Stehr M, von Loewenich VC, Wallander J, Wijnen R.

Pediatrics. 2013 Apr;131(4):796-800. doi: 10.1542/peds.2012-2896. Epub 2013 Mar 18.

PMID:
23509170
25.

Adenoidectomy in young children and serum IgG antibodies to pneumococcal surface protein A and choline binding protein A.

Mattila PS, Hammarén-Malmi S, Saxen H, Kaijalainen T, Käyhty H, Tarkkanen J.

Int J Pediatr Otorhinolaryngol. 2012 Nov;76(11):1569-74. doi: 10.1016/j.ijporl.2012.07.013. Epub 2012 Jul 24.

PMID:
22835927
26.

ADH1 expression inversely correlates with CDR1 and CDR2 in Candida albicans from chronic oral candidosis in APECED (APS-I) patients.

Siikala E, Bowyer P, Richardson M, Saxen H, Sanglard D, Rautemaa R.

FEMS Yeast Res. 2011 Sep;11(6):494-8. doi: 10.1111/j.1567-1364.2011.00739.x. Epub 2011 Jun 16.

27.

Modeling reveals that dynamic regulation of c-FLIP levels determines cell-to-cell distribution of CD95-mediated apoptosis.

Toivonen HT, Meinander A, Asaoka T, Westerlund M, Pettersson F, Mikhailov A, Eriksson JE, Saxén H.

J Biol Chem. 2011 May 27;286(21):18375-82. doi: 10.1074/jbc.M110.177097. Epub 2011 Feb 15.

28.

Persistent Candida albicans colonization and molecular mechanisms of azole resistance in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) patients.

Siikala E, Rautemaa R, Richardson M, Saxen H, Bowyer P, Sanglard D.

J Antimicrob Chemother. 2010 Dec;65(12):2505-13. doi: 10.1093/jac/dkq354. Epub 2010 Sep 28.

PMID:
20876623
29.

Adenoidectomy and nasopharyngeal carriage of Streptococcus pneumoniae in young children.

Mattila PS, Hammarén-Malmi S, Saxen H, Kaijalainen T, Käyhty H, Tarkkanen J.

Arch Dis Child. 2010 Sep;95(9):696-702. doi: 10.1136/adc.2009.165654. Epub 2010 May 26.

PMID:
20504840
30.

[Evaluation of a feverish child].

Ruuskanen O, Saxén H, Mertsola J.

Duodecim. 2009;125(24):2709-14. Review. Finnish.

PMID:
20175324
31.

Candida albicans isolates from APECED patients show decreased susceptibility to miconazole.

Siikala E, Richardson M, Pfaller MA, Diekema DJ, Messer SA, Perheentupa J, Saxén H, Rautemaa R.

Int J Antimicrob Agents. 2009 Dec;34(6):607-9. doi: 10.1016/j.ijantimicag.2009.07.007. Epub 2009 Sep 11. No abstract available.

PMID:
19748230
32.

Effect of adenoidectomy on respiratory function: a randomised prospective study.

Mattila PS, Hammarén-Malmi S, Pelkonen AS, Malmberg LP, Mäkelä MJ, Saxen H, Tarkkanen J.

Arch Dis Child. 2009 May;94(5):366-70. doi: 10.1136/adc.2008.145664. Epub 2009 Jan 8.

PMID:
19131420
33.

Nosocomial bloodstream infections in children: an 8-year experience at a tertiary-care hospital in Finland.

Sarvikivi E, Lyytikäinen O, Vaara M, Saxén H.

Clin Microbiol Infect. 2008 Nov;14(11):1072-5. doi: 10.1111/j.1469-0691.2008.02079.x.

34.

Nosocomial infections after pediatric cardiac surgery.

Sarvikivi E, Lyytikäinen O, Nieminen H, Sairanen H, Saxén H.

Am J Infect Control. 2008 Oct;36(8):564-9. doi: 10.1016/j.ajic.2007.11.006.

PMID:
18926309
35.

Reduction of fluconazole susceptibility of Candida albicans in APECED patients due to long-term use of ketoconazole and miconazole.

Rautemaa R, Richardson M, Pfaller M, Perheentupa J, Saxen H.

Scand J Infect Dis. 2008;40(11-12):904-7. doi: 10.1080/00365540802275853.

PMID:
18651265
36.

Activity of amphotericin B, anidulafungin, caspofungin, micafungin, posaconazole, and voriconazole against Candida albicans with decreased susceptibility to fluconazole from APECED patients on long-term azole treatment of chronic mucocutaneous candidiasis.

Rautemaa R, Richardson M, Pfaller MA, Perheentupa J, Saxén H.

Diagn Microbiol Infect Dis. 2008 Oct;62(2):182-5. doi: 10.1016/j.diagmicrobio.2008.05.007. Epub 2008 Jul 1.

PMID:
18597968
37.

Respiratory viruses in laryngeal croup of young children.

Rihkanen H, Rönkkö E, Nieminen T, Komsi KL, Räty R, Saxen H, Ziegler T, Roivainen M, Söderlund-Venermo M, Beng AL, Hovi T, Pitkäranta A.

J Pediatr. 2008 May;152(5):661-5. doi: 10.1016/j.jpeds.2007.10.043. Epub 2008 Jan 22. Erratum in: J Pediatr. 2008 Jul;153(1):151. Anne, Lahtinen [corrected to Beng, Anne Lahtinen].

38.

A randomized, controlled trial of tonsillectomy in periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome.

Renko M, Salo E, Putto-Laurila A, Saxen H, Mattila PS, Luotonen J, Ruuskanen O, Uhari M.

J Pediatr. 2007 Sep;151(3):289-92. Epub 2007 Jun 14.

PMID:
17719940
39.

Decreased susceptibility of Candida albicans to azole antifungals: a complication of long-term treatment in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) patients.

Rautemaa R, Richardson M, Pfaller M, Koukila-Kähkölä P, Perheentupa J, Saxén H.

J Antimicrob Chemother. 2007 Oct;60(4):889-92. Epub 2007 Aug 17.

PMID:
17704513
40.

Passive smoking after tympanostomy and risk of recurrent acute otitis media.

Hammarén-Malmi S, Saxen H, Tarkkanen J, Mattila PS.

Int J Pediatr Otorhinolaryngol. 2007 Aug;71(8):1305-10. Epub 2007 Jun 19.

PMID:
17582514
41.

Asiantuntijoiden sidonnaisuudet näkyville.

Turunen JP, Heikinheimo M, Saxén H.

Duodecim. 2007;123(5):506-7. Finnish. No abstract available.

PMID:
17441638
42.

Ayräpään palkinto 2007 akatemiaprofessori Markku Laaksolle.

Saarela L, Saxén H.

Duodecim. 2007;123(1):15-7. Finnish. No abstract available.

PMID:
17328291
43.

[Use of pad gives accuracy to the diagnosis of urinary tract infections in children].

Uhari M, Saxén H, Mertsola J.

Duodecim. 2006;122(5):579-84. Review. Finnish. No abstract available.

PMID:
16669445
44.

Prevention and monitoring of invasive fungal infections in pediatric patients with cancer and hematologic disorders.

Hovi L, Saxen H, Saarinen-Pihkala UM, Vettenranta K, Meri T, Richardson M.

Pediatr Blood Cancer. 2007 Jan;48(1):28-34.

PMID:
16395687
45.

New antigens for serologic diagnosis of neuroborreliosis in children.

Heikkilä T, Saxen H, Seppälä I, Lönnqvist T, Sillanpää H, Lahdenne P.

Pediatr Infect Dis J. 2005 Aug;24(8):709-12.

PMID:
16094226
47.

Emergence of fluconazole resistance in a Candida parapsilosis strain that caused infections in a neonatal intensive care unit.

Sarvikivi E, Lyytikäinen O, Soll DR, Pujol C, Pfaller MA, Richardson M, Koukila-Kähkölä P, Luukkainen P, Saxén H.

J Clin Microbiol. 2005 Jun;43(6):2729-35.

48.

[Meningococcal sepsis in a 15-year old girl's knee].

Saxén H.

Duodecim. 2005;121(3):333. Finnish. No abstract available.

PMID:
15787296
49.

Incidence of Haemophilus influenzae type b meningitis during 18 years of vaccine use: observational study using routine hospital data.

Peltola H, Salo E, Saxén H.

BMJ. 2005 Jan 1;330(7481):18-9. Epub 2004 Nov 25. No abstract available.

50.

Clustering of Serratia marcescens infections in a neonatal intensive care unit.

Sarvikivi E, Lyytikäinen O, Salmenlinna S, Vuopio-Varkila J, Luukkainen P, Tarkka E, Saxén H.

Infect Control Hosp Epidemiol. 2004 Sep;25(9):723-9.

PMID:
15484795

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