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Items: 1 to 50 of 70

1.

Quantification of multiphoton and fluorescence images of reproductive tissues from a mouse ovarian cancer model shows promise for early disease detection.

Sawyer TW, Koevary JW, Rice FPS, Howard CC, Austin OJ, Connolly DC, Cai KQ, Barton JK.

J Biomed Opt. 2019 Sep;24(9):1-16. doi: 10.1117/1.JBO.24.9.096010.

2.

Evaluation of segmentation algorithms for optical coherence tomography images of ovarian tissue.

Sawyer TW, Rice PFS, Sawyer DM, Koevary JW, Barton JK.

J Med Imaging (Bellingham). 2019 Jan;6(1):014002. doi: 10.1117/1.JMI.6.1.014002. Epub 2019 Jan 29.

PMID:
30746391
3.

Three-dimensional texture analysis of optical coherence tomography images of ovarian tissue.

Sawyer TW, Chandra S, Rice PFS, Koevary JW, Barton JK.

Phys Med Biol. 2018 Dec 4;63(23):235020. doi: 10.1088/1361-6560/aaefd2.

PMID:
30511664
4.

Hair follicle miRNAs: a novel biomarker for primary blast Induced-Mild traumatic brain injury.

Zhang J, Knight R, Wang Y, Sawyer TW, Martyniuk CJ, Langlois VS.

Biomarkers. 2019 Mar;24(2):166-179. doi: 10.1080/1354750X.2018.1531929. Epub 2018 Nov 13.

PMID:
30280938
5.

Alignment of sensor arrays in optical instruments using a geometric approach.

Sawyer TW.

Appl Opt. 2018 Feb 1;57(4):794-801. doi: 10.1364/AO.57.000794.

PMID:
29400760
6.

Comprehensive assessment of shockwave intensity: Transcriptomic biomarker discovery for primary blast-induced mild traumatic brain injury using the mammalian hair follicle.

Zhang J, Knight R, Wang Y, Sawyer TW, Martyniuk CJ, Langlois VS.

Brain Inj. 2018;32(1):123-134. doi: 10.1080/02699052.2017.1342000. Epub 2017 Nov 20.

PMID:
29157017
7.

Using confidence intervals to evaluate the focus alignment of spectrograph detector arrays.

Sawyer TW, Hawkins KS, Damento M.

Appl Opt. 2017 Jun 20;56(18):5295-5300. doi: 10.1364/AO.56.005295.

PMID:
29047583
8.

Primary Blast-Induced Changes in Akt and GSK Phosphorylation in Rat Hippocampus.

Wang Y, Sawyer TW, Tse YC, Fan C, Hennes G, Barnes J, Josey T, Weiss T, Nelson P, Wong TP.

Front Neurol. 2017 Aug 18;8:413. doi: 10.3389/fneur.2017.00413. eCollection 2017.

9.

Primary Blast Causes Delayed Effects without Cell Death in Shell-Encased Brain Cell Aggregates.

Sawyer TW, Ritzel DV, Wang Y, Josey T, Villanueva M, Nelson P, Song Y, Shei Y, Hennes G, Vair C, Parks S, Fan C, McLaws L.

J Neurotrauma. 2018 Jan 1;35(1):174-186. doi: 10.1089/neu.2016.4961. Epub 2017 Sep 14.

PMID:
28726571
10.

Tolerancing the alignment of large-core optical fibers, fiber bundles and light guides using a Fourier approach.

Sawyer TW, Petersburg R, Bohndiek SE.

Appl Opt. 2017 Apr 20;56(12):3303-3310. doi: 10.1364/AO.56.003303.

11.

Comparative toxicity of mono- and bifunctional alkylating homologues of sulphur mustard in human skin keratinocytes.

Sawyer TW, McNeely K, Louis K, Lecavalier P, Song Y, Villanueva M, Clewley R.

Toxicology. 2017 May 1;382:36-46. doi: 10.1016/j.tox.2017.03.005. Epub 2017 Mar 8.

PMID:
28285101
12.

The Effect of Underwater Blast on Aggregating Brain Cell Cultures.

Sawyer TW, Lee JJ, Villanueva M, Wang Y, Nelson P, Song Y, Fan C, Barnes J, McLaws L.

J Neurotrauma. 2017 Jan 15;34(2):517-528. doi: 10.1089/neu.2016.4430. Epub 2016 Jul 8.

PMID:
27163293
13.

High-Fidelity Simulation of Primary Blast: Direct Effects on the Head.

Sawyer TW, Wang Y, Ritzel DV, Josey T, Villanueva M, Shei Y, Nelson P, Hennes G, Weiss T, Vair C, Fan C, Barnes J.

J Neurotrauma. 2016 Jul 1;33(13):1181-93. doi: 10.1089/neu.2015.3914. Epub 2016 Mar 16.

PMID:
26582146
14.

Decontamination Efficacy and Skin Toxicity of Two Decontaminants against Bacillus anthracis.

Stratilo CW, Crichton MK, Sawyer TW.

PLoS One. 2015 Sep 22;10(9):e0138491. doi: 10.1371/journal.pone.0138491. eCollection 2015.

15.

Transcriptional profiling in rat hair follicles following simulated Blast insult: a new diagnostic tool for traumatic brain injury.

Zhang J, Carnduff L, Norman G, Josey T, Wang Y, Sawyer TW, Martyniuk CJ, Langlois VS.

PLoS One. 2014 Aug 19;9(8):e104518. doi: 10.1371/journal.pone.0104518. eCollection 2014.

16.

Primary blast-induced traumatic brain injury in rats leads to increased prion protein in plasma: a potential biomarker for blast-induced traumatic brain injury.

Pham N, Sawyer TW, Wang Y, Jazii FR, Vair C, Taghibiglou C.

J Neurotrauma. 2015 Jan 1;32(1):58-65. doi: 10.1089/neu.2014.3471.

17.

Non-cholinergic intervention of sarin nerve agent poisoning.

Sawyer TW, Mikler J, Tenn C, Bjarnason S, Frew R.

Toxicology. 2012 Apr 11;294(2-3):85-93. doi: 10.1016/j.tox.2012.02.003. Epub 2012 Feb 16.

PMID:
22343375
18.

Immobilization of Russian VX skin depots by localized cooling: implications for decontamination and medical countermeasures.

Mikler J, Tenn C, Worek F, Reiter G, Thiermann H, Garrett M, Bohnert S, Sawyer TW.

Toxicol Lett. 2011 Sep 25;206(1):47-53. doi: 10.1016/j.toxlet.2011.05.1047. Epub 2011 Jun 16.

PMID:
21704135
19.

The therapeutic use of localized cooling in the treatment of VX poisoning.

Sawyer TW, Mikler J, Worek F, Reiter G, Thiermann H, Tenn C, Weatherby K, Bohnert S.

Toxicol Lett. 2011 Jul 4;204(1):52-6. doi: 10.1016/j.toxlet.2011.04.008. Epub 2011 Apr 17.

PMID:
21530621
20.

Comparative protective effects of HI-6 and MMB-4 against organophosphorous nerve agent poisoning.

Lundy PM, Hamilton MG, Sawyer TW, Mikler J.

Toxicology. 2011 Jul 29;285(3):90-6. doi: 10.1016/j.tox.2011.04.006. Epub 2011 Apr 15. Review.

PMID:
21524678
21.

Ionic dependence of sulphur mustard cytotoxicity.

Sawyer TW, Nelson P, Bjarnason S, Vair C, Shei Y, Tenn C, Lecavalier P, Burczyk A.

Toxicol Appl Pharmacol. 2010 Sep 15;247(3):179-90. doi: 10.1016/j.taap.2010.06.010. Epub 2010 Jun 30.

PMID:
20600214
22.

Role of the sodium hydrogen exchanger in maitotoxin-induced cell death in cultured rat cortical neurons.

Wang Y, Weiss MT, Yin J, Frew R, Tenn C, Nelson PP, Vair C, Sawyer TW.

Toxicon. 2009 Aug;54(2):95-102. doi: 10.1016/j.toxicon.2009.03.018. Epub 2009 Mar 26.

PMID:
19328212
23.

Comparison of selected skin decontaminant products and regimens against VX in domestic swine.

Bjarnason S, Mikler J, Hill I, Tenn C, Garrett M, Caddy N, Sawyer TW.

Hum Exp Toxicol. 2008 Mar;27(3):253-61. doi: 10.1177/0960327108090269.

PMID:
18650258
24.
25.

Attenuation of maitotoxin-induced cytotoxicity in rat aortic smooth muscle cells by inhibitors of Na+/Ca2+ exchange, and calpain activation.

Frew R, Wang Y, Weiss TM, Nelson P, Sawyer TW.

Toxicon. 2008 Jun 15;51(8):1400-8. doi: 10.1016/j.toxicon.2008.03.015. Epub 2008 Mar 15.

PMID:
18460413
26.

Lack of a role for creatine phosphate kinase in sulphur mustard-induced cytotoxicity.

Nelson P, Burczyk A, Sawyer TW.

Hum Exp Toxicol. 2007 Nov;26(11):891-7.

PMID:
18042583
27.

pH-dependent toxicity of sulphur mustard in vitro.

Sawyer TW, Vair C, Nelson P, Shei Y, Bjarnason S, Tenn C, McWilliams M, Villanueva M, Burczyk A.

Toxicol Appl Pharmacol. 2007 Jun 15;221(3):363-71. Epub 2007 Mar 27.

PMID:
17482225
28.

Swine models in the design of more effective medical countermeasures against organophosphorus poisoning.

Dorandeu F, Mikler JR, Thiermann H, Tenn C, Davidson C, Sawyer TW, Lallement G, Worek F.

Toxicology. 2007 Apr 20;233(1-3):128-44. Epub 2006 Sep 29. Review.

PMID:
17092624
29.

Therapeutic effects of hypothermia on Lewisite toxicity.

Nelson P, Hancock JR, Sawyer TW.

Toxicology. 2006 May 1;222(1-2):8-16. Epub 2006 Feb 20.

PMID:
16488528
30.

Clinical aspects of percutaneous poisoning by the chemical warfare agent VX: effects of application site and decontamination.

Hamilton MG, Hill I, Conley J, Sawyer TW, Caneva DC, Lundy PM.

Mil Med. 2004 Nov;169(11):856-62.

PMID:
15605929
31.

Pharmacological differentiation of the P2X7 receptor and the maitotoxin-activated cationic channel.

Lundy PM, Nelson P, Mi L, Frew R, Minaker S, Vair C, Sawyer TW.

Eur J Pharmacol. 2004 Mar 8;487(1-3):17-28.

PMID:
15033372
32.

Hypothermia reduces sulphur mustard toxicity.

Mi L, Gong W, Nelson P, Martin L, Sawyer TW.

Toxicol Appl Pharmacol. 2003 Nov 15;193(1):73-83.

PMID:
14613718
33.

Therapeutic effects of cooling swine skin exposed to sulfur mustard.

Sawyer TW, Nelson P, Hill I, Conley JD, Blohm K, Davidson C, Sawyer TW.

Mil Med. 2002 Nov;167(11):939-43.

PMID:
12448623
34.

Site-specific percutaneous absorption of methyl salicylate and VX in domestic swine.

Duncan EJ, Brown A, Lundy P, Sawyer TW, Hamilton M, Hill I, Conley JD.

J Appl Toxicol. 2002 May-Jun;22(3):141-8.

PMID:
12015792
35.

Stimulation of Ca(2+) influx through ATP receptors on rat brain synaptosomes: identification of functional P2X(7) receptor subtypes.

Lundy PM, Hamilton MG, Mi L, Gong W, Vair C, Sawyer TW, Frew R.

Br J Pharmacol. 2002 Apr;135(7):1616-26.

36.

Volatile anesthetics give a false-positive reading in chemical agent monitors in the "H" mode.

Risk D, Verpy D, Conley JD, Jacobson T, Sawyer TW.

Mil Med. 2001 Aug;166(8):708-10.

PMID:
11515322
37.

A comparison of the effects of sarin and succinylcholine on respiratory parameters in anesthetized domestic swine.

Duncan EJ, Conley JD, Grychowski KD, Conley SA, Lundy PM, Hamilton MG, Sawyer TW.

Mil Med. 2001 Apr;166(4):322-7.

PMID:
11315472
38.

Domestic swine model for the assessment of chemical warfare agent-anesthetic interactions: some effects of sulfur mustard.

Conley J, Hunter K, Lundy P, Hamilton M, Sawyer TW.

Mil Med. 2000 Aug;165(8):573-8.

PMID:
10957847
39.
40.
41.

Effect of lowered temperature on the toxicity of sulphur mustard in vitro and in vivo.

Sawyer TW, Risk D.

Toxicology. 1999 May 3;134(1):27-37.

PMID:
10413186
42.

Toxicity of sulfur mustard in primary neuron culture.

Sawyer TW.

Toxicol In Vitro. 1999 Apr;13(2):249-58.

PMID:
20654482
43.
46.

l-thiocitrulline: A potent protective agent against the toxicity of sulphur mustard in vitro.

Sawyer TW, Hancock JR, D'Agostino PA.

Toxicol Appl Pharmacol. 1998 Aug;151(2):340-6.

PMID:
9707510
47.

MEIC Evaluation of Acute Systemic Toxicity: Part VI. The Prediction of Human Toxicity by Rodent LD50 Values and Results From 61 In Vitro Methods.

Ekwall B, Barile FA, Castano A, Clemedson C, Clothier RH, Dierickx P, Ekwall B, Ferro M, Fiskesjö G, Garza-Ocañas L, Gómez-Lechón MJ, Gülden M, Hall T, Isomaa B, Kahru A, Kerszman G, Kristen U, Kunimoto M, Kärenlampi S, Lewan L, Loukianov A, Ohno T, Persoone G, Romert L, Sawyer TW, Shrivastava R, Segner H, Stammati A, Tanaka N, Valentino M, Walum E, Zucco F.

Altern Lab Anim. 1998 Aug;26 Suppl 2:617-58. No abstract available.

PMID:
26042663
48.

Modification of cytosolic free calcium concentrations in human keratinocytes after sulfur mustard exposure.

Hamilton MG, Dorandeu FM, McCaffery M, Lundy PM, Sawyer TW.

Toxicol In Vitro. 1998 Aug;12(4):365-72.

PMID:
20654418
49.
50.

Protective effect of an inhibitor of nitric oxide synthase on sulphur mustard toxicity in vitro.

Sawyer TW, Lundy PM, Weiss MT.

Toxicol Appl Pharmacol. 1996 Nov;141(1):138-44.

PMID:
8917686

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