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Items: 1 to 50 of 187

1.

Distribution of corticotropin-releasing factor (CRF) receptor binding in the mouse brain using a new, high-affinity radioligand, [125 I]-PD-Sauvagine.

Tan LA, Vaughan JM, Perrin MH, Rivier JE, Sawchenko PE.

J Comp Neurol. 2017 Dec 15;525(18):3840-3864. doi: 10.1002/cne.24307. Epub 2017 Sep 13.

PMID:
28842924
2.

Pro-inflammatory immune-to-brain signaling is involved in neuroendocrine responses to acute emotional stress.

Serrats J, Grigoleit JS, Alvarez-Salas E, Sawchenko PE.

Brain Behav Immun. 2017 May;62:53-63. doi: 10.1016/j.bbi.2017.02.003. Epub 2017 Feb 4.

PMID:
28179107
3.

Antibodies to the RNA-binding protein hnRNP A1 contribute to neurodegeneration in a model of central nervous system autoimmune inflammatory disease.

Douglas JN, Gardner LA, Salapa HE, Lalor SJ, Lee S, Segal BM, Sawchenko PE, Levin MC.

J Neuroinflammation. 2016 Jul 8;13(1):178. doi: 10.1186/s12974-016-0647-y.

5.

Corticotropin-releasing factor receptor-1 antagonism mitigates beta amyloid pathology and cognitive and synaptic deficits in a mouse model of Alzheimer's disease.

Zhang C, Kuo CC, Moghadam SH, Monte L, Campbell SN, Rice KC, Sawchenko PE, Masliah E, Rissman RA.

Alzheimers Dement. 2016 May;12(5):527-37. doi: 10.1016/j.jalz.2015.09.007. Epub 2015 Nov 7.

6.

Evidence for involvement of a limbic paraventricular hypothalamic inhibitory network in hypothalamic-pituitary-adrenal axis adaptations to repeated stress.

Radley JJ, Sawchenko PE.

J Comp Neurol. 2015 Dec 15;523(18):2769-87. doi: 10.1002/cne.23815. Epub 2015 Jun 18.

7.

Characterization of a Pachymedusa dacnicolor-Sauvagine analog as a new high-affinity radioligand for corticotropin-releasing factor receptor studies.

Perrin MH, Tan LA, Vaughan JM, Lewis KA, Donaldson CJ, Miller C, Erchegyi J, Rivier JE, Sawchenko PE.

J Pharmacol Exp Ther. 2015 May;353(2):307-17. doi: 10.1124/jpet.114.222307. Epub 2015 Mar 3.

8.

VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation.

Grieder TE, Herman MA, Contet C, Tan LA, Vargas-Perez H, Cohen A, Chwalek M, Maal-Bared G, Freiling J, Schlosburg JE, Clarke L, Crawford E, Koebel P, Repunte-Canonigo V, Sanna PP, Tapper AR, Roberto M, Kieffer BL, Sawchenko PE, Koob GF, van der Kooy D, George O.

Nat Neurosci. 2014 Dec;17(12):1751-8. doi: 10.1038/nn.3872. Epub 2014 Nov 17.

9.

The anorectic actions of the TGFβ cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract.

Tsai VW, Manandhar R, Jørgensen SB, Lee-Ng KK, Zhang HP, Marquis CP, Jiang L, Husaini Y, Lin S, Sainsbury A, Sawchenko PE, Brown DA, Breit SN.

PLoS One. 2014 Jun 27;9(6):e100370. doi: 10.1371/journal.pone.0100370. eCollection 2014.

10.

Immune cell trafficking from the brain maintains CNS immune tolerance.

Mohammad MG, Tsai VW, Ruitenberg MJ, Hassanpour M, Li H, Hart PH, Breit SN, Sawchenko PE, Brown DA.

J Clin Invest. 2014 Mar;124(3):1228-41. doi: 10.1172/JCI71544. Epub 2014 Feb 24.

11.

Reprint of: policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich et al.

Gore AC, Balthazart J, Bikle D, Carpenter DO, Crews D, Czernichow P, Diamanti-Kandarakis E, Dores RM, Grattan D, Hof PR, Hollenberg AN, Lange C, Lee AV, Levine JE, Millar RP, Nelson RJ, Porta M, Poth M, Power DM, Prins GS, Ridgway EC, Rissman EF, Romijn JA, Sawchenko PE, Sly PD, Söder O, Taylor HS, Tena-Sempere M, Vaudry H, Wallen K, Wang Z, Wartofsky L, Watson CS.

Horm Behav. 2014 Feb;65(2):190-3. doi: 10.1016/j.yhbeh.2013.09.001. Epub 2013 Nov 28. No abstract available.

PMID:
24289987
12.

Reprint of: policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich, et al.

Gore AC, Balthazart J, Bikle D, Carpenter DO, Crews D, Czernichow P, Diamanti-Kandarakis E, Dores RM, Grattan D, Hof PR, Hollenberg AN, Lange C, Lee AV, Levine JE, Millar RP, Nelson RJ, Porta M, Poth M, Power DM, Prins GS, Ridgway EC, Rissman EF, Romijn JA, Sawchenko PE, Sly PD, Söder O, Taylor HS, Tena-Sempere M, Vaudry H, Wallen K, Wang Z, Wartofsky L, Watson CS.

Front Neuroendocrinol. 2014 Jan;35(1):2-5. doi: 10.1016/j.yfrne.2013.09.003. Epub 2013 Nov 21. No abstract available.

PMID:
24268499
13.

Policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich et al.

Gore AC, Balthazart J, Bikle D, Carpenter DO, Crews D, Czernichow P, Diamanti-Kandarakis E, Dores RM, Grattan D, Hof PR, Hollenberg AN, Lange C, Lee AV, Levine JE, Millar RP, Nelson RJ, Porta M, Poth M, Power DM, Prins GS, Ridgway EC, Rissman EF, Romijn JA, Sawchenko PE, Sly PD, Söder O, Taylor HS, Tena-Sempere M, Vaudry H, Wallen K, Wang Z, Wartofsky L, Watson CS.

Andrology. 2013 Nov;1(6):802-5. doi: 10.1111/j.2047-2927.2013.00151.x. No abstract available.

14.

Policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich et al.

Gore AC, Balthazart J, Bikle D, Carpenter DO, Crews D, Czernichow P, Diamanti-Kandarakis E, Dores RM, Grattan D, Hof PR, Hollenberg AN, Lange C, Lee AV, Levine JE, Millar RP, Nelson RJ, Porta M, Poth M, Power DM, Prins GS, Ridgway EC, Rissman EF, Romijn JA, Sawchenko PE, Sly PD, Söder O, Taylor HS, Tena-Sempere M, Vaudry H, Wallen K, Wang Z, Wartofsky L, Watson CS.

Horm Res Paediatr. 2013;80(5):305-8. doi: 10.1159/000355668. Epub 2013 Oct 9. No abstract available.

15.

Policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich et al.

Gore AC, Balthazart J, Bikle D, Carpenter DO, Crews D, Czernichow P, Diamanti-Kandarakis E, Dores RM, Grattan D, Hof PR, Hollenberg AN, Lange C, Lee AV, Levine JE, Millar RP, Nelson RJ, Porta M, Poth M, Power DM, Prins GS, Ridgway EC, Rissman EF, Romijn JA, Sawchenko PE, Sly PD, Söder O, Taylor HS, Tena-Sempere M, Vaudry H, Wallen K, Wang Z, Wartofsky L, Watson CS.

Eur J Endocrinol. 2013 Oct 21;169(6):E1-4. doi: 10.1530/EJE-13-0763. Print 2013 Dec. No abstract available.

PMID:
24057478
16.

Policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich et al.

Gore AC, Balthazart J, Bikle D, Carpenter DO, Crews D, Czernichow P, Diamanti-Kandarakis E, Dores RM, Grattan D, Hof PR, Hollenberg AN, Lange C, Lee AV, Levine JE, Millar RP, Nelson RJ, Porta M, Poth M, Power DM, Prins GS, Ridgway EC, Rissman EF, Romijn JA, Sawchenko PE, Sly PD, Söder O, Taylor HS, Tena-Sempere M, Vaudry H, Wallen K, Wang Z, Wartofsky L, Watson CS.

Endocrinology. 2013 Nov;154(11):3957-60. doi: 10.1210/en.2013-1854. Epub 2013 Sep 18. No abstract available.

17.

Posttranslational processing of human and mouse urocortin 2: characterization and bioactivity of gene products.

Vaughan JM, Donaldson CJ, Fischer WH, Perrin MH, Rivier JE, Sawchenko PE, Vale WW.

Endocrinology. 2013 Apr;154(4):1553-64. doi: 10.1210/en.2012-2011. Epub 2013 Mar 14.

18.

Dendritic cells and multiple sclerosis: disease, tolerance and therapy.

Mohammad MG, Hassanpour M, Tsai VW, Li H, Ruitenberg MJ, Booth DW, Serrats J, Hart PH, Symonds GP, Sawchenko PE, Breit SN, Brown DA.

Int J Mol Sci. 2012 Dec 27;14(1):547-62. doi: 10.3390/ijms14010547. Review.

19.

Corticotropin-releasing factor receptor-dependent effects of repeated stress on tau phosphorylation, solubility, and aggregation.

Rissman RA, Staup MA, Lee AR, Justice NJ, Rice KC, Vale W, Sawchenko PE.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6277-82. doi: 10.1073/pnas.1203140109. Epub 2012 Mar 26.

20.

CCAAT/enhancer binding protein-δ expression by dendritic cells regulates CNS autoimmune inflammatory disease.

Tsai VW, Mohammad MG, Tolhurst O, Breit SN, Sawchenko PE, Brown DA.

J Neurosci. 2011 Nov 30;31(48):17612-21. doi: 10.1523/JNEUROSCI.3449-11.2011.

21.

Lipopolysaccharide-induced tau phosphorylation and kinase activity--modulation, but not mediation, by corticotropin-releasing factor receptors.

Roe AD, Staup MA, Serrats J, Sawchenko PE, Rissman RA.

Eur J Neurosci. 2011 Aug;34(3):448-56. doi: 10.1111/j.1460-9568.2011.07764.x. Epub 2011 Jul 4.

22.

A common substrate for prefrontal and hippocampal inhibition of the neuroendocrine stress response.

Radley JJ, Sawchenko PE.

J Neurosci. 2011 Jun 29;31(26):9683-95. doi: 10.1523/JNEUROSCI.6040-10.2011.

23.

Dual roles for perivascular macrophages in immune-to-brain signaling.

Serrats J, Schiltz JC, García-Bueno B, van Rooijen N, Reyes TM, Sawchenko PE.

Neuron. 2010 Jan 14;65(1):94-106. doi: 10.1016/j.neuron.2009.11.032.

24.

Cerebrovascular cyclooxygenase-1 expression, regulation, and role in hypothalamic-pituitary-adrenal axis activation by inflammatory stimuli.

García-Bueno B, Serrats J, Sawchenko PE.

J Neurosci. 2009 Oct 14;29(41):12970-81. doi: 10.1523/JNEUROSCI.2373-09.2009.

25.

How T-cell-dependent and -independent challenges access the brain: vascular and neural responses to bacterial lipopolysaccharide and staphylococcal enterotoxin B.

Serrats J, Sawchenko PE.

Brain Behav Immun. 2009 Oct;23(7):1038-52. doi: 10.1016/j.bbi.2009.06.004. Epub 2009 Jun 12.

26.

A discrete GABAergic relay mediates medial prefrontal cortical inhibition of the neuroendocrine stress response.

Radley JJ, Gosselink KL, Sawchenko PE.

J Neurosci. 2009 Jun 3;29(22):7330-40. doi: 10.1523/JNEUROSCI.5924-08.2009.

27.

Loss of modifier of cell adhesion reveals a pathway leading to axonal degeneration.

Chen Q, Peto CA, Shelton GD, Mizisin A, Sawchenko PE, Schubert D.

J Neurosci. 2009 Jan 7;29(1):118-30. doi: 10.1523/JNEUROSCI.3985-08.2009.

29.

The Creb1 coactivator Crtc1 is required for energy balance and fertility.

Altarejos JY, Goebel N, Conkright MD, Inoue H, Xie J, Arias CM, Sawchenko PE, Montminy M.

Nat Med. 2008 Oct;14(10):1112-7. doi: 10.1038/nm.1866. Epub 2008 Aug 31.

30.

Noradrenergic innervation of the dorsal medial prefrontal cortex modulates hypothalamo-pituitary-adrenal responses to acute emotional stress.

Radley JJ, Williams B, Sawchenko PE.

J Neurosci. 2008 May 28;28(22):5806-16. doi: 10.1523/JNEUROSCI.0552-08.2008.

31.

A unique sorting nexin regulates trafficking of potassium channels via a PDZ domain interaction.

Lunn ML, Nassirpour R, Arrabit C, Tan J, McLeod I, Arias CM, Sawchenko PE, Yates JR 3rd, Slesinger PA.

Nat Neurosci. 2007 Oct;10(10):1249-59. Epub 2007 Sep 2.

PMID:
17828261
32.

Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation.

Rissman RA, Lee KF, Vale W, Sawchenko PE.

J Neurosci. 2007 Jun 13;27(24):6552-62.

33.
35.
36.

Cellular and molecular bases of the initiation of fever.

Steiner AA, Ivanov AI, Serrats J, Hosokawa H, Phayre AN, Robbins JR, Roberts JL, Kobayashi S, Matsumura K, Sawchenko PE, Romanovsky AA.

PLoS Biol. 2006 Sep;4(9):e284.

37.
38.

A soluble mouse brain splice variant of type 2alpha corticotropin-releasing factor (CRF) receptor binds ligands and modulates their activity.

Chen AM, Perrin MH, Digruccio MR, Vaughan JM, Brar BK, Arias CM, Lewis KA, Rivier JE, Sawchenko PE, Vale WW.

Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2620-5. Epub 2005 Feb 8.

39.

Brainstem prolactin-releasing peptide neurons are sensitive to stress and lactation.

Morales T, Sawchenko PE.

Neuroscience. 2003;121(3):771-8.

PMID:
14568035
40.

Signaling the brain in systemic inflammation: the role of perivascular cells.

Schiltz JC, Sawchenko PE.

Front Biosci. 2003 Sep 1;8:s1321-9. Review.

PMID:
12957837
41.

Magic peptides, magic antibodies: guidelines for appropriate controls for immunohistochemistry.

Saper CB, Sawchenko PE.

J Comp Neurol. 2003 Oct 13;465(2):161-3. No abstract available.

PMID:
12949777
42.

Categorically distinct acute stressors elicit dissimilar transcriptional profiles in the paraventricular nucleus of the hypothalamus.

Reyes TM, Walker JR, DeCino C, Hogenesch JB, Sawchenko PE.

J Neurosci. 2003 Jul 2;23(13):5607-16.

43.
44.

Human urocortin II, a selective agonist for the type 2 corticotropin-releasing factor receptor, decreases feeding and drinking in the rat.

Inoue K, Valdez GR, Reyes TM, Reinhardt LE, Tabarin A, Rivier J, Vale WW, Sawchenko PE, Koob GF, Zorrilla EP.

J Pharmacol Exp Ther. 2003 Apr;305(1):385-93.

PMID:
12649393
46.
48.
50.

Reduced hippocampal neurogenesis in adult transgenic mice with chronic astrocytic production of interleukin-6.

Vallières L, Campbell IL, Gage FH, Sawchenko PE.

J Neurosci. 2002 Jan 15;22(2):486-92.

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