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Items: 1 to 50 of 97

1.
2.

Fabrication of solid lipid nanoparticles of lurasidone HCl for oral delivery: optimization, in vitro characterization, cell line studies and in vivo efficacy in schizophrenia.

Patel MH, Mundada VP, Sawant KK.

Drug Dev Ind Pharm. 2019 Aug;45(8):1242-1257. doi: 10.1080/03639045.2019.1593434. Epub 2019 Jun 6.

PMID:
30880488
3.

Hyaluronic acid tethered pH-responsive alloy-drug nanoconjugates for multimodal therapy of glioblastoma: An intranasal route approach.

Pandey A, Singh K, Patel S, Singh R, Patel K, Sawant K.

Mater Sci Eng C Mater Biol Appl. 2019 May;98:419-436. doi: 10.1016/j.msec.2018.12.139. Epub 2019 Jan 3.

PMID:
30813043
4.
6.

Comparative Study for Optimization of Pharmaceutical Self-Emulsifying Pre-concentrate by Design of Experiment and Artificial Neural Network.

Parikh KJ, Sawant KK.

AAPS PharmSciTech. 2018 Oct;19(7):3311-3321. doi: 10.1208/s12249-018-1173-2. Epub 2018 Sep 14.

PMID:
30218266
7.

Rap1 GTPase promotes coordinated collective cell migration in vivo.

Sawant K, Chen Y, Kotian N, Preuss KM, McDonald JA.

Mol Biol Cell. 2018 Nov 1;29(22):2656-2673. doi: 10.1091/mbc.E17-12-0752. Epub 2018 Aug 29.

8.

Lysines and Arginines play non-redundant roles in mediating chemokine-glycosaminoglycan interactions.

Joseph PRB, Sawant KV, Iwahara J, Garofalo RP, Desai UR, Rajarathnam K.

Sci Rep. 2018 Aug 16;8(1):12289. doi: 10.1038/s41598-018-30697-y.

9.

Extended release delivery system of metoprolol succinate using hot-melt extrusion: effect of release modifier on methacrylic acid copolymer.

Sawant KP, Fule R, Maniruzzaman M, Amin PD.

Drug Deliv Transl Res. 2018 Dec;8(6):1679-1693. doi: 10.1007/s13346-018-0545-1.

PMID:
29948916
10.

Preclinical Study of Ibuprofen Loaded Transnasal Mucoadhesive Microemulsion for Neuroprotective Effect in MPTP Mice Model.

Mandal S, Mandal SD, Chuttani K, Sawant KK, Subudhi BB.

Iran J Pharm Res. 2018 Winter;17(1):23-38.

11.

Cholic acid-modified polyethylenimine: in vitro and in vivo studies.

Dube B, Pandey A, Joshi G, Mulherkar R, Sawant K.

Int J Nanomedicine. 2018 Mar 15;13(T-NANO 2014 Abstracts):83-85. doi: 10.2147/IJN.S124693. eCollection 2018.

12.

Development of Novel Octanoyl Chitosan Nanoparticles for Improved Rifampicin Pulmonary Delivery: Optimization by Factorial Design.

Petkar KC, Chavhan S, Kunda N, Saleem I, Somavarapu S, Taylor KMG, Sawant KK.

AAPS PharmSciTech. 2018 May;19(4):1758-1772. doi: 10.1208/s12249-018-0972-9. Epub 2018 Mar 27.

PMID:
29589222
13.

Glycosaminoglycan Interactions Fine-Tune Chemokine-Mediated Neutrophil Trafficking: Structural Insights and Molecular Mechanisms.

Rajarathnam K, Sepuru KM, Joseph PRB, Sawant KV, Brown AJ.

J Histochem Cytochem. 2018 Apr;66(4):229-239. doi: 10.1369/0022155417739864. Epub 2018 Jan 1. Review.

14.
15.

Platelet-Derived Chemokine CXCL7 Dimer Preferentially Exists in the Glycosaminoglycan-Bound Form: Implications for Neutrophil-Platelet Crosstalk.

Brown AJ, Sepuru KM, Sawant KV, Rajarathnam K.

Front Immunol. 2017 Oct 2;8:1248. doi: 10.3389/fimmu.2017.01248. eCollection 2017.

16.

Albumin based versatile multifunctional nanocarriers for cancer therapy: Fabrication, surface modification, multimodal therapeutics and imaging approaches.

Kudarha RR, Sawant KK.

Mater Sci Eng C Mater Biol Appl. 2017 Dec 1;81:607-626. doi: 10.1016/j.msec.2017.08.004. Epub 2017 Aug 3. Review.

PMID:
28888016
17.

Chemokine CXCL7 Heterodimers: Structural Insights, CXCR2 Receptor Function, and Glycosaminoglycan Interactions.

Brown AJ, Joseph PR, Sawant KV, Rajarathnam K.

Int J Mol Sci. 2017 Apr 1;18(4). pii: E748. doi: 10.3390/ijms18040748.

18.

Hydrophobically modified polyethylenimine-based ternary complexes for targeting brain tumor: stability, in vitro and in vivo studies.

Dube B, Pandey A, Joshi G, Sawant K.

Artif Cells Nanomed Biotechnol. 2017 Dec;45(8):1685-1698. doi: 10.1080/21691401.2017.1282497. Epub 2017 Feb 17.

PMID:
28278583
19.

A novel nanoparticles impregnated ocular insert for enhanced bioavailability to posterior segment of eye: In vitro, in vivo and stability studies.

Rathod LV, Kapadia R, Sawant KK.

Mater Sci Eng C Mater Biol Appl. 2017 Feb 1;71:529-540. doi: 10.1016/j.msec.2016.10.017. Epub 2016 Oct 15.

PMID:
27987741
20.

Submicron Emulsions and Their Applications in Oral Delivery.

Mundada V, Patel M, Sawant K.

Crit Rev Ther Drug Carrier Syst. 2016;33(3):265-308. Review.

PMID:
27910752
21.

Chemokine CXCL1 mediated neutrophil recruitment: Role of glycosaminoglycan interactions.

Sawant KV, Poluri KM, Dutta AK, Sepuru KM, Troshkina A, Garofalo RP, Rajarathnam K.

Sci Rep. 2016 Sep 14;6:33123. doi: 10.1038/srep33123.

22.

Polyethylenimine: A versatile, multifunctional non-viral vector for nucleic acid delivery.

Pandey AP, Sawant KK.

Mater Sci Eng C Mater Biol Appl. 2016 Nov 1;68:904-918. doi: 10.1016/j.msec.2016.07.066. Epub 2016 Jul 26. Review.

PMID:
27524093
23.
24.

Aripiprazole loaded poly(caprolactone) nanoparticles: Optimization and in vivo pharmacokinetics.

Sawant K, Pandey A, Patel S.

Mater Sci Eng C Mater Biol Appl. 2016 Sep 1;66:230-243. doi: 10.1016/j.msec.2016.04.089. Epub 2016 Apr 27.

PMID:
27207059
25.

Dynamic myosin activation promotes collective morphology and migration by locally balancing oppositional forces from surrounding tissue.

Aranjuez G, Burtscher A, Sawant K, Majumder P, McDonald JA.

Mol Biol Cell. 2016 Jun 15;27(12):1898-910. doi: 10.1091/mbc.E15-10-0744. Epub 2016 Apr 27.

26.

Design and evaluation of mucoadhesive microemulsion for neuroprotective effect of ibuprofen following intranasal route in the MPTP mice model.

Mandal S, Mandal SD, Chuttani K, Sawant KK, Subudhi BB.

Drug Dev Ind Pharm. 2016 Aug;42(8):1340-50. doi: 10.3109/03639045.2015.1135936. Epub 2016 Jan 24.

PMID:
26710671
27.

Cefdinir nanosuspension for improved oral bioavailability by media milling technique: formulation, characterization and in vitro-in vivo evaluations.

Sawant KK, Patel MH, Patel K.

Drug Dev Ind Pharm. 2016;42(5):758-68. doi: 10.3109/03639045.2015.1104344. Epub 2015 Nov 7.

PMID:
26548349
28.

Formulation of cyclodextrin inclusion complex-based orally disintegrating tablet of eslicarbazepine acetate for improved oral bioavailability.

Desai S, Poddar A, Sawant K.

Mater Sci Eng C Mater Biol Appl. 2016 Jan 1;58:826-34. doi: 10.1016/j.msec.2015.09.019. Epub 2015 Sep 8.

PMID:
26478377
29.

Multidimensional Measurement of Household Water Poverty in a Mumbai Slum: Looking Beyond Water Quality.

Subbaraman R, Nolan L, Sawant K, Shitole S, Shitole T, Nanarkar M, Patil-Deshmukh A, Bloom DE.

PLoS One. 2015 Jul 21;10(7):e0133241. doi: 10.1371/journal.pone.0133241. eCollection 2015.

30.

Chemokine CXCL1-Mediated Neutrophil Trafficking in the Lung: Role of CXCR2 Activation.

Sawant KV, Xu R, Cox R, Hawkins H, Sbrana E, Kolli D, Garofalo RP, Rajarathnam K.

J Innate Immun. 2015;7(6):647-58. doi: 10.1159/000430914. Epub 2015 Jul 1.

31.

The psychological toll of slum living in Mumbai, India: a mixed methods study.

Subbaraman R, Nolan L, Shitole T, Sawant K, Shitole S, Sood K, Nanarkar M, Ghannam J, Betancourt TS, Bloom DE, Patil-Deshmukh A.

Soc Sci Med. 2014 Oct;119:155-69. doi: 10.1016/j.socscimed.2014.08.021. Epub 2014 Aug 19.

32.

Enhanced bioavailability and intestinal uptake of Gemcitabine HCl loaded PLGA nanoparticles after oral delivery.

Joshi G, Kumar A, Sawant K.

Eur J Pharm Sci. 2014 Aug 18;60:80-9. doi: 10.1016/j.ejps.2014.04.014. Epub 2014 May 6.

PMID:
24810394
33.

A system for household enumeration and re-identification in densely populated slums to facilitate community research, education, and advocacy.

Thomson DR, Shitole S, Shitole T, Sawant K, Subbaraman R, Bloom DE, Patil-Deshmukh A.

PLoS One. 2014 Apr 10;9(4):e93925. doi: 10.1371/journal.pone.0093925. eCollection 2014.

34.

Improvement in antihypertensive and antianginal effects of felodipine by enhanced absorption from PLGA nanoparticles optimized by factorial design.

Shah U, Joshi G, Sawant K.

Mater Sci Eng C Mater Biol Appl. 2014 Feb 1;35:153-63. doi: 10.1016/j.msec.2013.10.038. Epub 2013 Nov 14.

PMID:
24411363
35.

Solid lipid nanoparticle-incorporated gel: the future treatment for skin infections?

Kumar A, Sawant KK.

Nanomedicine (Lond). 2013 Dec;8(12):1901-3. doi: 10.2217/nnm.13.171. No abstract available.

PMID:
24279486
36.

Dynamic conformational switching in the chemokine ligand is essential for G-protein-coupled receptor activation.

Joseph PR, Sawant KV, Isley A, Pedroza M, Garofalo RP, Richardson RM, Rajarathnam K.

Biochem J. 2013 Dec 1;456(2):241-51. doi: 10.1042/BJ20130148.

37.

Cholic acid modified 2 kDa polyethylenimine as efficient transfection agent.

Dube B, Rose L, Sawant K, Uludag H.

Biotechnol Prog. 2013 Sep-Oct;29(5):1337-41. doi: 10.1002/btpr.1799. Epub 2013 Sep 18.

PMID:
23955845
38.

Application of multiple regression analysis in optimization of anastrozole-loaded PLGA nanoparticles.

Kumar A, Sawant KK.

J Microencapsul. 2014;31(2):105-14. doi: 10.3109/02652048.2013.808280. Epub 2013 Jul 24.

PMID:
23883302
39.

Molecular basis of glycosaminoglycan heparin binding to the chemokine CXCL1 dimer.

Poluri KM, Joseph PR, Sawant KV, Rajarathnam K.

J Biol Chem. 2013 Aug 30;288(35):25143-53. doi: 10.1074/jbc.M113.492579. Epub 2013 Jul 17.

40.

Simvastatin nanoemulsion for improved oral delivery: design, characterisation, in vitro and in vivo studies.

Chavhan SS, Petkar KC, Sawant KK.

J Microencapsul. 2013;30(8):771-9. doi: 10.3109/02652048.2013.788085. Epub 2013 Apr 30.

PMID:
23631382
41.

The high cost of diarrhoeal illness for urban slum households-a cost-recovery approach: a cohort study.

Patel RB, Stoklosa H, Shitole S, Shitole T, Sawant K, Nanarkar M, Subbaraman R, Ridpath A, Patil-Deshmuk A.

BMJ Open. 2013 Apr 3;3(4). pii: e002251. doi: 10.1136/bmjopen-2012-002251. Print 2013.

42.

Development of solid lipid nanoparticles based controlled release system for topical delivery of terbinafine hydrochloride.

Vaghasiya H, Kumar A, Sawant K.

Eur J Pharm Sci. 2013 May 13;49(2):311-22. doi: 10.1016/j.ejps.2013.03.013. Epub 2013 Apr 2.

PMID:
23557842
43.

Chemokine CXCL1 dimer is a potent agonist for the CXCR2 receptor.

Ravindran A, Sawant KV, Sarmiento J, Navarro J, Rajarathnam K.

J Biol Chem. 2013 Apr 26;288(17):12244-52. doi: 10.1074/jbc.M112.443762. Epub 2013 Mar 11.

44.

The social ecology of water in a Mumbai slum: failures in water quality, quantity, and reliability.

Subbaraman R, Shitole S, Shitole T, Sawant K, O'Brien J, Bloom DE, Patil-Deshmukh A.

BMC Public Health. 2013 Feb 26;13:173. doi: 10.1186/1471-2458-13-173.

45.

Off the map: the health and social implications of being a non-notified slum in India.

Subbaraman R, O'Brien J, Shitole T, Shitole S, Sawant K, Bloom DE, Patil-Deshmukh A.

Environ Urban. 2012 Oct;24(2):643-663.

46.

Genetic interaction screens identify a role for hedgehog signaling in Drosophila border cell migration.

Geisbrecht ER, Sawant K, Su Y, Liu ZC, Silver DL, Burtscher A, Wang X, Zhu AJ, McDonald JA.

Dev Dyn. 2013 May;242(5):414-31. doi: 10.1002/dvdy.23926. Epub 2013 Feb 8.

47.

Design and development of multiple emulsion for enhancement of oral bioavailability of acyclovir.

Paul S, Kumar A, Yedurkar P, Sawant K.

Drug Dev Ind Pharm. 2013 Nov;39(11):1809-17. doi: 10.3109/03639045.2012.738682. Epub 2013 Jan 2.

PMID:
23281917
48.
49.

Floating microspheres of valacyclovir HCl: Formulation, optimization, characterization, in vitro and in vivo floatability studies.

Goswami N, Joshi G, Sawant K.

J Pharm Bioallied Sci. 2012 Mar;4(Suppl 1):S8-9. doi: 10.4103/0975-7406.94118.

50.

Formulation and characterization of Cefuroxime Axetil nanoemulsion for improved bioavailability.

Patel Y, Poddar A, Sawant K.

J Pharm Bioallied Sci. 2012 Mar;4(Suppl 1):S4-5. doi: 10.4103/0975-7406.94116.

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