Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 135

1.

Genome-wide DNA methylation analysis in ankylosing spondylitis identifies HLA-B*27 dependent and independent DNA methylation changes in whole blood.

Coit P, Kaushik P, Caplan L, Kerr GS, Walsh JA, Dubreuil M, Reimold A, Sawalha AH.

J Autoimmun. 2019 May 23. pii: S0896-8411(19)30130-1. doi: 10.1016/j.jaut.2019.04.022. [Epub ahead of print]

PMID:
31128893
2.

Inhibition of EZH2 ameliorates lupus-like disease in MRL/lpr mice.

Rohraff DM, He Y, Farkash EA, Schonfeld M, Tsou PS, Sawalha AH.

Arthritis Rheumatol. 2019 May 20. doi: 10.1002/art.40931. [Epub ahead of print]

PMID:
31106974
3.

Structural variation of centromeric endogenous retroviruses in human populations and their impact on cutaneous T-cell lymphoma, Sézary syndrome, and HIV infection.

Kaplan MH, Kaminski M, Estes JM, Gitlin SD, Zahn J, Elder JT, Tejasvi T, Gensterblum E, Sawalha AH, McGowan JP, Dosik MH, Direskeneli H, Direskeneli GS, Adebamowo SN, Adebamowo CA, Sajadi M, Contreras-Galindo R.

BMC Med Genomics. 2019 May 2;12(1):58. doi: 10.1186/s12920-019-0505-8.

4.

Identification of Cysteine-Rich Angiogenic Inducer 61 as a Potential Antifibrotic and Proangiogenic Mediator in Scleroderma.

Tsou PS, Khanna D, Sawalha AH.

Arthritis Rheumatol. 2019 Mar 18. doi: 10.1002/art.40890. [Epub ahead of print]

PMID:
30884213
5.

Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma.

Tsou PS, Campbell P, Amin MA, Coit P, Miller S, Fox DA, Khanna D, Sawalha AH.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3695-3702. doi: 10.1073/pnas.1813006116. Epub 2019 Feb 12.

6.

Hypomethylation of STAT1 and HLA-DRB1 is associated with type-I interferon-dependent HLA-DRB1 expression in lupus CD8+ T cells.

Miller S, Tsou PS, Coit P, Gensterblum-Miller E, Renauer P, Rohraff DM, Kilian NC, Schonfeld M, Sawalha AH.

Ann Rheum Dis. 2019 Apr;78(4):519-528. doi: 10.1136/annrheumdis-2018-214323. Epub 2019 Jan 23.

PMID:
30674474
7.

Evaluating the Perception Among Rheumatologists of Maintenance of Board Certification in the US.

Sawalha AH, Coit P.

Arthritis Care Res (Hoboken). 2019 Mar;71(3):337-342. doi: 10.1002/acr.23823.

PMID:
30570838
8.

Genome-wide DNA methylation analysis in primary antiphospholipid syndrome neutrophils.

Weeding E, Coit P, Yalavarthi S, Kaplan MJ, Knight JS, Sawalha AH.

Clin Immunol. 2018 Nov;196:110-116. doi: 10.1016/j.clim.2018.11.011. Epub 2018 Nov 22.

PMID:
30471352
9.

Clinical immunology: A special issue on epigenetics.

Sawalha AH.

Clin Immunol. 2018 Nov;196:1-2. doi: 10.1016/j.clim.2018.11.012. Epub 2018 Nov 22. No abstract available.

PMID:
30468773
10.

Monogenic Lupus: A Developing Paradigm of Disease.

Alperin JM, Ortiz-Fernández L, Sawalha AH.

Front Immunol. 2018 Oct 30;9:2496. doi: 10.3389/fimmu.2018.02496. eCollection 2018. Review.

11.

Analysis of the genetic component of systemic sclerosis in Iranian and Turkish populations through a genome-wide association study.

González-Serna D, López-Isac E, Yilmaz N, Gharibdoost F, Jamshidi A, Kavosi H, Poursani S, Farsad F, Direskeneli H, Saruhan-Direskeneli G, Vargas S, Sawalha AH, Brown MA, Yavuz S, Mahmoudi M, Martin J.

Rheumatology (Oxford). 2019 Feb 1;58(2):289-298. doi: 10.1093/rheumatology/key281.

PMID:
30247649
12.

Drug-induced lupus erythematosus: an update on drugs and mechanisms.

He Y, Sawalha AH.

Curr Opin Rheumatol. 2018 Sep;30(5):490-497. doi: 10.1097/BOR.0000000000000522.

PMID:
29870500
13.

Methyl-CpG-binding protein 2 mediates antifibrotic effects in scleroderma fibroblasts.

He Y, Tsou PS, Khanna D, Sawalha AH.

Ann Rheum Dis. 2018 Aug;77(8):1208-1218. doi: 10.1136/annrheumdis-2018-213022. Epub 2018 May 14.

PMID:
29760157
14.

Deoxyribonucleic Acid Methylation in Systemic Lupus Erythematosus: Implications for Future Clinical Practice.

Weeding E, Sawalha AH.

Front Immunol. 2018 Apr 24;9:875. doi: 10.3389/fimmu.2018.00875. eCollection 2018. Review.

15.

Caffeine inhibits STAT1 signaling and downregulates inflammatory pathways involved in autoimmunity.

Iris M, Tsou PS, Sawalha AH.

Clin Immunol. 2018 Jul;192:68-77. doi: 10.1016/j.clim.2018.04.008. Epub 2018 Apr 18.

PMID:
29678503
16.

Shared epitope-aryl hydrocarbon receptor crosstalk underlies the mechanism of gene-environment interaction in autoimmune arthritis.

Fu J, Nogueira SV, Drongelen VV, Coit P, Ling S, Rosloniec EF, Sawalha AH, Holoshitz J.

Proc Natl Acad Sci U S A. 2018 May 1;115(18):4755-4760. doi: 10.1073/pnas.1722124115. Epub 2018 Apr 16.

17.

Management of Behçet's disease.

Alibaz-Oner F, Sawalha AH, Direskeneli H.

Curr Opin Rheumatol. 2018 May;30(3):238-242. doi: 10.1097/BOR.0000000000000497. Review.

PMID:
29432223
18.

Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis.

Ortiz-Fernández L, Carmona FD, López-Mejías R, González-Escribano MF, Lyons PA, Morgan AW, Sawalha AH, Smith KGC, González-Gay MA, Martín J; Spanish GCA Study Group, UK GCA Consortium, Turkish Takayasu Study Group, Vasculitis Clinical Research Consortium, IgAV Study Group, AAV Study group.

Ann Rheum Dis. 2018 Apr;77(4):589-595. doi: 10.1136/annrheumdis-2017-212372. Epub 2018 Jan 27. Erratum in: Ann Rheum Dis. 2018 Jun;77(6):950.

19.

A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis.

Munz M, Willenborg C, Richter GM, Jockel-Schneider Y, Graetz C, Staufenbiel I, Wellmann J, Berger K, Krone B, Hoffmann P, van der Velde N, Uitterlinden AG, de Groot LCPGM, Sawalha AH, Direskeneli H, Saruhan-Direskeneli G, Guzeldemir-Akcakanat E, Keceli HG, Laudes M, Noack B, Teumer A, Holtfreter B, Kocher T, Eickholz P, Meyle J, Doerfer C, Bruckmann C, Lieb W, Franke A, Schreiber S, Nohutcu RM, Erdmann J, Loos BG, Jepsen S, Dommisch H, Schaefer AS.

Hum Mol Genet. 2018 Mar 1;27(5):941-942. doi: 10.1093/hmg/ddy015. No abstract available.

PMID:
29346566
20.

Novel Transcriptional Activity and Extensive Allelic Imbalance in the Human MHC Region.

Gensterblum-Miller E, Wu W, Sawalha AH.

J Immunol. 2018 Feb 15;200(4):1496-1503. doi: 10.4049/jimmunol.1701061. Epub 2018 Jan 8.

21.

Behçet's disease in the United States: A single center descriptive and comparative study.

Kilian NC, Sawalha AH.

Eur J Rheumatol. 2017 Dec;4(4):239-244. doi: 10.5152/eurjrheum.2017.17112. Epub 2017 Nov 3.

22.

Sex chromosome contributions to sex differences in multiple sclerosis susceptibility and progression.

Voskuhl RR, Sawalha AH, Itoh Y.

Mult Scler. 2018 Jan;24(1):22-31. doi: 10.1177/1352458517737394.

23.

Editorial: The Innate and Adaptive Immune Response Are Both Involved in Drug-Induced Autoimmunity.

Sawalha AH.

Arthritis Rheumatol. 2018 Mar;70(3):330-333. doi: 10.1002/art.40371. Epub 2018 Jan 30. No abstract available.

24.

CD4+CD28+KIR+CD11ahi T cells correlate with disease activity and are characterized by a pro-inflammatory epigenetic and transcriptional profile in lupus patients.

Gensterblum E, Renauer P, Coit P, Strickland FM, Kilian NC, Miller S, Ognenovski M, Wren JD, Tsou PS, Lewis EE, Maksimowicz-McKinnon K, McCune WJ, Richardson BC, Sawalha AH.

J Autoimmun. 2018 Jan;86:19-28. doi: 10.1016/j.jaut.2017.09.011. Epub 2017 Oct 20.

25.

EZH2 Modulates the DNA Methylome and Controls T Cell Adhesion Through Junctional Adhesion Molecule A in Lupus Patients.

Tsou PS, Coit P, Kilian NC, Sawalha AH.

Arthritis Rheumatol. 2018 Jan;70(1):98-108. doi: 10.1002/art.40338. Epub 2017 Dec 15.

26.

An update on the role of epigenetics in systemic vasculitis.

Coit P, Direskeneli H, Sawalha AH.

Curr Opin Rheumatol. 2018 Jan;30(1):4-15. doi: 10.1097/BOR.0000000000000451. Review.

27.

Activated signature of antiphospholipid syndrome neutrophils reveals potential therapeutic target.

Knight JS, Meng H, Coit P, Yalavarthi S, Sule G, Gandhi AA, Grenn RC, Mazza LF, Ali RA, Renauer P, Wren JD, Bockenstedt PL, Wang H, Eitzman DT, Sawalha AH.

JCI Insight. 2017 Sep 21;2(18). pii: 93897. doi: 10.1172/jci.insight.93897. eCollection 2017 Sep 21.

28.

The genetics of Takayasu arteritis.

Renauer P, Sawalha AH.

Presse Med. 2017 Jul - Aug;46(7-8 Pt 2):e179-e187. doi: 10.1016/j.lpm.2016.11.031. Epub 2017 Jul 26.

29.

Unfolding the pathogenesis of scleroderma through genomics and epigenomics.

Tsou PS, Sawalha AH.

J Autoimmun. 2017 Sep;83:73-94. doi: 10.1016/j.jaut.2017.05.004. Epub 2017 May 16. Review.

30.

Epigenetic Variability in Systemic Lupus Erythematosus: What We Learned from Genome-Wide DNA Methylation Studies.

Teruel M, Sawalha AH.

Curr Rheumatol Rep. 2017 Jun;19(6):32. doi: 10.1007/s11926-017-0657-5. Review.

31.

A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis.

Munz M, Willenborg C, Richter GM, Jockel-Schneider Y, Graetz C, Staufenbiel I, Wellmann J, Berger K, Krone B, Hoffmann P, van der Velde N, Uitterlinden AG, de Groot LCPGM, Sawalha AH, Direskeneli H, Saruhan-Direskeneli G, Guzeldemir-Akcakanat E, Keceli HG, Laudes M, Noack B, Teumer A, Holtfreter B, Kocher T, Eickholz P, Meyle J, Doerfer C, Bruckmann C, Lieb W, Franke A, Schreiber S, Nohutcu RM, Erdmann J, Loos BG, Jepsen S, Dommisch H, Schaefer AS.

Hum Mol Genet. 2017 Jul 1;26(13):2577-2588. doi: 10.1093/hmg/ddx151. Erratum in: Hum Mol Genet. 2018 Mar 1;27(5):941-942.

PMID:
28449029
32.

Corrigendum: Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy.

Carmona FD, Coit P, Saruhan-Direskeneli G, Hernández-Rodríguez J, Cid MC, Solans R, Castañeda S, Vaglio A, Direskeneli H, Merkel PA, Boiardi L, Salvarani C, González-Gay MA, Martín J, Sawalha AH; Spanish GCA Study Group; Italian GCA Study Group; Turkish Takayasu Study Group; Vasculitis Clinical Research Consortium.

Sci Rep. 2017 Apr 5;7:46012. doi: 10.1038/srep46012. No abstract available.

33.

Interview with Amr H Sawalha: epigenetics and autoimmunity.

Sawalha AH.

Epigenomics. 2017 Apr;9(4):379-382. doi: 10.2217/epi-2017-0005. Epub 2017 Mar 21.

34.

Age-associated DNA methylation changes in naive CD4+ T cells suggest an evolving autoimmune epigenotype in aging T cells.

Dozmorov MG, Coit P, Maksimowicz-McKinnon K, Sawalha AH.

Epigenomics. 2017 Apr;9(4):429-445. doi: 10.2217/epi-2016-0143. Epub 2017 Mar 21.

35.

Clinical Images: Black Esophagus in Antiphospholipid Syndrome.

Padda A, Mandalia A, Sawalha AH.

Arthritis Rheumatol. 2017 Jul;69(7):1460. doi: 10.1002/art.40092. Epub 2017 May 23. No abstract available.

36.

Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy.

Carmona FD, Coit P, Saruhan-Direskeneli G, Hernández-Rodríguez J, Cid MC, Solans R, Castañeda S, Vaglio A, Direskeneli H, Merkel PA, Boiardi L, Salvarani C, González-Gay MA, Martín J, Sawalha AH; Spanish GCA Study Group; Italian GCA Study Group; Turkish Takayasu Study Group; Vasculitis Clinical Research Consortium.

Sci Rep. 2017 Mar 9;7:43953. doi: 10.1038/srep43953. Erratum in: Sci Rep. 2017 Apr 05;7:46012.

37.

Genome-wide profiling identifies associations between lupus nephritis and differential methylation of genes regulating tissue hypoxia and type 1 interferon responses.

Mok A, Solomon O, Nayak RR, Coit P, Quach HL, Nititham J, Sawalha AH, Barcellos LF, Criswell LA, Chung SA.

Lupus Sci Med. 2016 Dec 7;3(1):e000183. doi: 10.1136/lupus-2016-000183. eCollection 2016.

38.

The human microbiome in rheumatic autoimmune diseases: A comprehensive review.

Coit P, Sawalha AH.

Clin Immunol. 2016 Sep;170:70-9. doi: 10.1016/j.clim.2016.07.026. Epub 2016 Aug 2. Review.

PMID:
27493014
39.

Histone Deacetylase 5 Is Overexpressed in Scleroderma Endothelial Cells and Impairs Angiogenesis via Repression of Proangiogenic Factors.

Tsou PS, Wren JD, Amin MA, Schiopu E, Fox DA, Khanna D, Sawalha AH.

Arthritis Rheumatol. 2016 Dec;68(12):2975-2985. doi: 10.1002/art.39828.

40.

Sequencing of 16S rRNA reveals a distinct salivary microbiome signature in Behçet's disease.

Coit P, Mumcu G, Ture-Ozdemir F, Unal AU, Alpar U, Bostanci N, Ergun T, Direskeneli H, Sawalha AH.

Clin Immunol. 2016 Aug;169:28-35. doi: 10.1016/j.clim.2016.06.002. Epub 2016 Jun 7.

PMID:
27283393
41.

Genetic heterogeneity within the HLA region in three distinct clinical subgroups of myasthenia gravis.

Saruhan-Direskeneli G, Hughes T, Yilmaz V, Durmus H, Adler A, Alahgholi-Hajibehzad M, Aysal F, Yentür SP, Akalin MA, Dogan O, Marx A, Gülsen-Parman Y, Oflazer P, Deymeer F, Sawalha AH.

Clin Immunol. 2016 May;166-167:81-8. doi: 10.1016/j.clim.2016.05.003. Epub 2016 May 12.

PMID:
27181991
42.

Histone H2AX phosphorylation as a measure of DNA double-strand breaks and a marker of environmental stress and disease activity in lupus.

Namas R, Renauer P, Ognenovski M, Tsou PS, Sawalha AH.

Lupus Sci Med. 2016 Apr 29;3(1):e000148. doi: 10.1136/lupus-2016-000148. eCollection 2016.

43.

Analysis of Systemic Sclerosis-associated Genes in a Turkish Population.

Carmona FD, Onat AM, Fernández-Aranguren T, Serrano-Fernández A, Robledo G, Direskeneli H, Sawalha AH, Yavuz S, Martín J.

J Rheumatol. 2016 Jul;43(7):1376-9. doi: 10.3899/jrheum.160045. Epub 2016 May 1.

PMID:
27134258
44.

Epigenetic Reprogramming in Naive CD4+ T Cells Favoring T Cell Activation and Non-Th1 Effector T Cell Immune Response as an Early Event in Lupus Flares.

Coit P, Dozmorov MG, Merrill JT, McCune WJ, Maksimowicz-McKinnon K, Wren JD, Sawalha AH.

Arthritis Rheumatol. 2016 Sep;68(9):2200-9. doi: 10.1002/art.39720.

45.

IFI44L promoter methylation as a blood biomarker for systemic lupus erythematosus.

Zhao M, Zhou Y, Zhu B, Wan M, Jiang T, Tan Q, Liu Y, Jiang J, Luo S, Tan Y, Wu H, Renauer P, Del Mar Ayala Gutiérrez M, Castillo Palma MJ, Ortega Castro R, Fernández-Roldán C, Raya E, Faria R, Carvalho C, Alarcón-Riquelme ME, Xiang Z, Chen J, Li F, Ling G, Zhao H, Liao X, Lin Y, Sawalha AH, Lu Q.

Ann Rheum Dis. 2016 Nov;75(11):1998-2006. doi: 10.1136/annrheumdis-2015-208410. Epub 2016 Jan 19.

46.

Genome-Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Subchondral Bone and Similarity to Overlying Cartilage.

Jeffries MA, Donica M, Baker LW, Stevenson ME, Annan AC, Beth Humphrey M, James JA, Sawalha AH.

Arthritis Rheumatol. 2016 Jun;68(6):1403-14. doi: 10.1002/art.39555.

47.

Whole Exome Sequencing Identifies Rare Protein-Coding Variants in Behçet's Disease.

Ognenovski M, Renauer P, Gensterblum E, Kötter I, Xenitidis T, Henes JC, Casali B, Salvarani C, Direskeneli H, Kaufman KM, Sawalha AH.

Arthritis Rheumatol. 2016 May;68(5):1272-80. doi: 10.1002/art.39545.

48.

Ethnicity-specific epigenetic variation in naïve CD4+ T cells and the susceptibility to autoimmunity.

Coit P, Ognenovski M, Gensterblum E, Maksimowicz-McKinnon K, Wren JD, Sawalha AH.

Epigenetics Chromatin. 2015 Nov 24;8:49. doi: 10.1186/s13072-015-0037-1. eCollection 2015.

49.

Epigenomic functional characterization of genetic susceptibility variants in systemic vasculitis.

Sawalha AH, Dozmorov MG.

J Autoimmun. 2016 Feb;67:76-81. doi: 10.1016/j.jaut.2015.10.002. Epub 2015 Oct 20.

50.

Systemic lupus erythematosus complicated by diffuse alveolar haemorrhage: risk factors, therapy and survival.

Kazzaz NM, Coit P, Lewis EE, McCune WJ, Sawalha AH, Knight JS.

Lupus Sci Med. 2015 Sep 23;2(1):e000117. doi: 10.1136/lupus-2015-000117. eCollection 2015.

Supplemental Content

Loading ...
Support Center