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Items: 1 to 50 of 411

1.

Identification of benzo[d]pyrrolo[2,1-b]thiazole derivatives as CENP-E inhibitors.

Yamane M, Sawada JI, Ogo N, Ohba M, Ando T, Asai A.

Biochem Biophys Res Commun. 2019 Sep 14. pii: S0006-291X(19)31749-8. doi: 10.1016/j.bbrc.2019.09.028. [Epub ahead of print]

PMID:
31530389
2.

Selective inhibition of spindle microtubules by a tubulin-binding quinazoline derivative.

Sawada JI, Ishii H, Matsuno K, Sato M, Suzuki Y, Asai A.

Mol Pharmacol. 2019 Aug 30. pii: mol.119.116624. doi: 10.1124/mol.119.116624. [Epub ahead of print]

3.

Structural and Thermodynamic Basis of the Enhanced Interaction between Kinesin Spindle Protein Eg5 and STLC-type Inhibitors.

Yokoyama H, Sawada JI, Sato K, Ogo N, Kamei N, Ishikawa Y, Hara K, Asai A, Hashimoto H.

ACS Omega. 2018 Sep 28;3(9):12284-12294. doi: 10.1021/acsomega.8b00778. eCollection 2018 Sep 30.

4.

Mitochondria Penetrating Peptide-Conjugated TAMRA for Live-Cell Long-Term Tracking.

Zhao T, Liu X, Singh S, Liu X, Zhang Y, Sawada J, Komatsu M, Belfield KD.

Bioconjug Chem. 2019 Sep 18;30(9):2312-2316. doi: 10.1021/acs.bioconjchem.9b00465. Epub 2019 Aug 23.

PMID:
31433175
5.

Anti-signal Recognition Particle Antibody-positive Necrotizing Myopathy with Secondary Cardiomyopathy: The First Myocardial Biopsy- and Multimodal Imaging-proven Case.

Takeguchi-Kikuchi S, Hayasaka T, Katayama T, Kano K, Takahashi K, Saito T, Sawada J, Minoshima A, Sakamoto N, Akasaka K, Miyokawa N, Nishino I, Ishibashi-Ueda H, Hasebe N.

Intern Med. 2019 Jul 10. doi: 10.2169/internalmedicine.2564-18. [Epub ahead of print]

6.

High-risk screening for Anderson-Fabry disease in patients with cardiac, renal, or neurological manifestations.

Nakagawa N, Sawada J, Sakamoto N, Takeuchi T, Takahashi F, Maruyama JI, Momosaki K, Nakamura K, Endo F, Hasebe N.

J Hum Genet. 2019 Sep;64(9):891-898. doi: 10.1038/s10038-019-0633-1. Epub 2019 Jun 19.

PMID:
31213654
7.

A Guiding Principle for Strengthening Crosslinked Polymers: Synthesis and Application of Mobility-Controlling Rotaxane Crosslinkers.

Sawada J, Aoki D, Otsuka H, Takata T.

Angew Chem Int Ed Engl. 2019 Feb 25;58(9):2765-2768. doi: 10.1002/anie.201813439. Epub 2019 Jan 25.

PMID:
30600883
8.

Pericyte-Specific Ninjurin1 Deletion Attenuates Vessel Maturation and Blood Flow Recovery in Hind Limb Ischemia.

Minoshima A, Kabara M, Matsuki M, Yoshida Y, Kano K, Tomita Y, Hayasaka T, Horiuchi K, Saito Y, Aonuma T, Nishimura M, Maruyama K, Nakagawa N, Sawada J, Takehara N, Hasebe N, Kawabe JI.

Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):2358-2370. doi: 10.1161/ATVBAHA.118.311375.

9.

Local extensive granulomatous inflammation of the neck region and lymphangitis caused by Lichtheimia corymbifera infection in a Japanese Black calf.

Teh APP, Hirai T, Ito S, Hidaka Y, Goto Y, Furukawa H, Sawada J, Yamaguchi R.

Med Mycol Case Rep. 2018 Apr 17;21:37-40. doi: 10.1016/j.mmcr.2018.04.001. eCollection 2018 Sep.

10.

Prolonged activation of cAMP signaling leads to endothelial barrier disruption via transcriptional repression of RRAS.

Perrot CY, Sawada J, Komatsu M.

FASEB J. 2018 May 18:fj201700818RRR. doi: 10.1096/fj.201700818RRR. [Epub ahead of print]

11.

SLCO1B1 Polymorphism Is a Drug Response Predictive Marker for Advanced Pancreatic Cancer Patients Treated With Gemcitabine, S-1, or Gemcitabine Plus S-1.

Sato Y, Ueno H, Ioka T, Ohkawa S, Ikeda M, Shimamura T, Tsuji A, Tsuchiya Y, Furuse J, Ishii H, Furuya K, Iguchi H, Saito Y, Kaniwa N, Sawada JI, Sakamoto H, Sekine A, Okusaka T, Yoshida T; GEST.

Pancreas. 2018 May/Jun;47(5):637-642. doi: 10.1097/MPA.0000000000001052.

PMID:
29683977
12.

[A case of neurolymphomatosis that was diagnosed by acoustic nerve biopsy].

Asanome A, Kano K, Takahashi K, Saito T, Sawada J, Katayama T.

Rinsho Shinkeigaku. 2018 Feb 28;58(2):93-99. doi: 10.5692/clinicalneurol.cn-001080. Epub 2018 Jan 31. Japanese.

PMID:
29386492
13.

Neuromyelitis optica spectrum disorder secondary to treatment with anti-PD-1 antibody nivolumab: the first report.

Narumi Y, Yoshida R, Minami Y, Yamamoto Y, Takeguchi S, Kano K, Takahashi K, Saito T, Sawada J, Terui H, Katayama T, Sasaki T, Ohsaki Y.

BMC Cancer. 2018 Jan 24;18(1):95. doi: 10.1186/s12885-018-3997-2.

14.

R-Ras-Akt axis induces endothelial lumenogenesis and regulates the patency of regenerating vasculature.

Li F, Sawada J, Komatsu M.

Nat Commun. 2017 Nov 23;8(1):1720. doi: 10.1038/s41467-017-01865-x.

15.

Investigating toxicity specific to adjuvanted vaccines.

Matsumoto M, Komatsu SI, Ikeda T, Shimomura K, Watanabe K, Hirabayashi K, Sawada JI, Maki K, Shinoda K, Fueki O, Onodera H.

Regul Toxicol Pharmacol. 2017 Dec;91:29-38. doi: 10.1016/j.yrtph.2017.09.003. Epub 2017 Sep 6. Review.

PMID:
28888957
16.

Limbic Encephalitis Associated with Human Herpesvirus-7 (HHV-7) in an Immunocompetent Adult: The First Reported Case in Japan.

Aburakawa Y, Katayama T, Saito T, Sawada J, Suzutani T, Aizawa H, Hasebe N.

Intern Med. 2017;56(14):1919-1923. doi: 10.2169/internalmedicine.56.8185. Epub 2017 Jul 15.

17.

Cerebral Infarction by Paradoxical Gas Embolism During Laparoscopic Liver Resection with Injury of the Hepatic Vessels in a Patient without a Right-to-Left Systemic Shunt.

Kawahara T, Hagiwara M, Takahashi H, Tanaka M, Imai K, Sawada J, Kunisawa T, Furukawa H.

Am J Case Rep. 2017 Jun 20;18:687-691.

18.

Formation of Tough Films by Evaporation of Water from Dispersions of Elastomer Microspheres Crosslinked with Rotaxane Supramolecules.

Hiroshige S, Kureha T, Aoki D, Sawada J, Aoki D, Takata T, Suzuki D.

Chemistry. 2017 Jun 22;23(35):8405-8408. doi: 10.1002/chem.201702077. Epub 2017 Jun 5.

PMID:
28493449
19.

Multicomponent Assembly of the Kinesin Spindle Protein Inhibitor CPUYJ039 and Analogues as Antimitotic Agents.

Carbajales C, Sawada JI, Marzaro G, Sotelo E, Escalante L, Sánchez-Díaz Marta A, García-Mera X, Asai A, Coelho A.

ACS Comb Sci. 2017 Mar 13;19(3):153-160. doi: 10.1021/acscombsci.6b00166. Epub 2017 Feb 17.

PMID:
28135059
20.

A case of acute autonomic and sensory neuropathy (AASN) with antibody against a mixture of galactocerebroside and phospholipids.

Ishikura T, Takata K, Kinoshita M, Fukada K, Sawada J, Hazama T.

Rinsho Shinkeigaku. 2017 Jan 31;57(1):33-36. doi: 10.5692/clinicalneurol.cn-000914. Epub 2016 Dec 23. Japanese.

PMID:
28025409
21.

Biopsy-proven case of Epstein-Barr virus (EBV)-associated vasculitis of the central nervous system.

Kano K, Katayama T, Takeguchi S, Asanome A, Takahashi K, Saito T, Sawada J, Saito M, Anei R, Kamada K, Miyokawa N, Nishihara H, Hasebe N.

Neuropathology. 2017 Jun;37(3):259-264. doi: 10.1111/neup.12356. Epub 2016 Dec 22.

PMID:
28004435
22.

Functional 1,3a,6a-triazapentalene scaffold: Design of fluorescent probes for kinesin spindle protein (KSP).

Sawada JI, Osawa A, Takeuchi T, Kaneda M, Oishi S, Fujii N, Asai A, Tanino K, Namba K.

Bioorg Med Chem Lett. 2016 Dec 1;26(23):5765-5769. doi: 10.1016/j.bmcl.2016.10.047. Epub 2016 Oct 15.

PMID:
27793568
23.

Cu-Cr-O Functionalized ETS-2 Nanoparticles for Hot Gas Desulfurization.

Yazdanbakhsh F, Alizadehgiashi M, Bläsing M, Müller M, Sawada JA, Kuznicki SM.

J Nanosci Nanotechnol. 2016 Jan;16(1):878-84.

PMID:
27398540
24.

The Motor Unit Number Index of Subclinical Abnormality in Amyotrophic Lateral Sclerosis.

Fukada K, Matsui T, Furuta M, Hirozawa D, Matsui M, Kajiyama Y, Shimizu M, Kinoshita M, Mochizuki H, Sawada JI, Hazama T.

J Clin Neurophysiol. 2016 Dec;33(6):564-568.

PMID:
27295331
25.

Opposing effects of acute and chronic d-amphetamine on decision-making in rats.

Wong SA, Thapa R, Badenhorst CA, Briggs AR, Sawada JA, Gruber AJ.

Neuroscience. 2017 Mar 14;345:218-228. doi: 10.1016/j.neuroscience.2016.04.021. Epub 2016 Apr 23.

PMID:
27113327
26.

R-Ras Inhibits VEGF-Induced p38MAPK Activation and HSP27 Phosphorylation in Endothelial Cells.

Sawada J, Li F, Komatsu M.

J Vasc Res. 2015;52(5):347-59. doi: 10.1159/000444526. Epub 2016 Mar 31.

27.

A clinoptilolite-PDMS mixed-matrix membrane for high temperature water softening.

Yazdanbakhsh F, Alizadehgiashi M, Sawada JA, Kuznicki SM.

Water Sci Technol. 2016;73(6):1409-17. doi: 10.2166/wst.2015.615.

PMID:
27003083
28.

The Long Noncoding RNA SPRIGHTLY Regulates Cell Proliferation in Primary Human Melanocytes.

Zhao W, Mazar J, Lee B, Sawada J, Li JL, Shelley J, Govindarajan S, Towler D, Mattick JS, Komatsu M, Dinger ME, Perera RJ.

J Invest Dermatol. 2016 Apr;136(4):819-828. doi: 10.1016/j.jid.2016.01.018. Epub 2016 Jan 29.

29.

A Sporadic Case of Fabry Disease Involving Repeated Fever, Psychiatric Symptoms, Headache, and Ischemic Stroke in an Adult Japanese Woman.

Sawada J, Katayama T, Kano K, Asanome A, Takahashi K, Saito T, Chinda J, Nakagawa N, Sato N, Kimura T, Yahara O, Momosaki K, Nakamura K, Hasebe N.

Intern Med. 2015;54(23):3069-74. doi: 10.2169/internalmedicine.54.4719. Epub 2015 Dec 1.

30.

Construction of possible integrated predictive index based on EGFR and ANXA3 polymorphisms for chemotherapy response in fluoropyrimidine-treated Japanese gastric cancer patients using a bioinformatic method.

Takahashi H, Kaniwa N, Saito Y, Sai K, Hamaguchi T, Shirao K, Shimada Y, Matsumura Y, Ohtsu A, Yoshino T, Doi T, Takahashi A, Odaka Y, Okuyama M, Sawada J, Sakamoto H, Yoshida T.

BMC Cancer. 2015 Oct 16;15:718. doi: 10.1186/s12885-015-1721-z.

31.

Monoethanolamine Impregnation of Titanosilicate Zeolite ETS-10.

Tanchuk B, Sawada JA, Kuznicki SM.

J Nanosci Nanotechnol. 2015 Mar;15(3):2556-63.

PMID:
26413705
32.

Structure-Guided Design of Novel l-Cysteine Derivatives as Potent KSP Inhibitors.

Ogo N, Ishikawa Y, Sawada J, Matsuno K, Hashimoto A, Asai A.

ACS Med Chem Lett. 2015 Jul 22;6(9):1004-9. doi: 10.1021/acsmedchemlett.5b00221. eCollection 2015 Sep 10.

33.

Severe parkinsonism associated with anti-CRMP5 antibody-positive paraneoplastic neurological syndrome and abnormal signal intensity in the bilateral basal ganglia.

Tada S, Furuta M, Fukada K, Hirozawa D, Matsui M, Aoike F, Okuno T, Sawada J, Mochizuki H, Hazama T.

J Neurol Neurosurg Psychiatry. 2016 Aug;87(8):907-10. doi: 10.1136/jnnp-2015-311569. Epub 2015 Sep 15. No abstract available.

34.

RGD-conjugated two-photon absorbing near-IR emitting fluorescent probes for tumor vasculature imaging.

Yue X, Morales AR, Githaiga GW, Woodward AW, Tang S, Sawada J, Komatsu M, Liu X, Belfield KD.

Org Biomol Chem. 2015 Nov 21;13(43):10716-25. doi: 10.1039/c5ob01536g.

35.

Developmental origin of age-related coronary artery disease.

Wei K, Díaz-Trelles R, Liu Q, Diez-Cuñado M, Scimia MC, Cai W, Sawada J, Komatsu M, Boyle JJ, Zhou B, Ruiz-Lozano P, Mercola M.

Cardiovasc Res. 2015 Jul 15;107(2):287-94. doi: 10.1093/cvr/cvv167. Epub 2015 Jun 8.

36.

Non-vitamin k antagonist oral anticoagulants do not increase cerebral microbleeds.

Saito T, Kawamura Y, Sato N, Kano K, Takahashi K, Asanome A, Sawada J, Katayama T, Hasebe N.

J Stroke Cerebrovasc Dis. 2015 Jun;24(6):1373-7. doi: 10.1016/j.jstrokecerebrovasdis.2015.02.018. Epub 2015 Apr 4.

37.

Preparation of a titania/X-zeolite/porous glass composite photocatalyst using hydrothermal and drop coating processes.

Yasumori A, Yanagida S, Sawada J.

Molecules. 2015 Jan 30;20(2):2349-63. doi: 10.3390/molecules20022349.

38.
39.

Structural basis of new allosteric inhibition in Kinesin spindle protein Eg5.

Yokoyama H, Sawada J, Katoh S, Matsuno K, Ogo N, Ishikawa Y, Hashimoto H, Fujii S, Asai A.

ACS Chem Biol. 2015 Apr 17;10(4):1128-36. doi: 10.1021/cb500939x. Epub 2015 Feb 3.

PMID:
25622007
40.

Infant feeding practice in medieval Japan: stable carbon and nitrogen isotope analysis of human skeletons from Yuigahama-minami.

Tsutaya T, Shimomi A, Nagaoka T, Sawada J, Hirata K, Yoneda M.

Am J Phys Anthropol. 2015 Feb;156(2):241-51. doi: 10.1002/ajpa.22643. Epub 2014 Oct 21.

PMID:
25331669
41.

Severely affected ALS patients have broad and high expectations for brain-machine interfaces.

Kageyama Y, Hirata M, Yanagisawa T, Shimokawa T, Sawada J, Morris S, Mizushima N, Kishima H, Sakura O, Yoshimine T.

Amyotroph Lateral Scler Frontotemporal Degener. 2014 Dec;15(7-8):513-9. doi: 10.3109/21678421.2014.951943. Epub 2014 Sep 10.

PMID:
25204774
42.

Combination therapy for segmental craniocervical dystonia (Meige syndrome) with aripiprazole, trihexyphenidyl, and botulinum toxin: three cases reports.

Saito T, Katayama T, Sawada J, Kano K, Asanome A, Takahashi K, Sato N, Hasebe N.

Neurol Sci. 2015 Feb;36(2):243-5. doi: 10.1007/s10072-014-1927-x. Epub 2014 Aug 24.

PMID:
25151364
43.

Application of a combination of a knowledge-based algorithm and 2-stage screening to hypothesis-free genomic data on irinotecan-treated patients for identification of a candidate single nucleotide polymorphism related to an adverse effect.

Takahashi H, Sai K, Saito Y, Kaniwa N, Matsumura Y, Hamaguchi T, Shimada Y, Ohtsu A, Yoshino T, Doi T, Okuda H, Ichinohe R, Takahashi A, Doi A, Odaka Y, Okuyama M, Saijo N, Sawada J, Sakamoto H, Yoshida T.

PLoS One. 2014 Aug 15;9(8):e105160. doi: 10.1371/journal.pone.0105160. eCollection 2014.

44.

Artificial brains. A million spiking-neuron integrated circuit with a scalable communication network and interface.

Merolla PA, Arthur JV, Alvarez-Icaza R, Cassidy AS, Sawada J, Akopyan F, Jackson BL, Imam N, Guo C, Nakamura Y, Brezzo B, Vo I, Esser SK, Appuswamy R, Taba B, Amir A, Flickner MD, Risk WP, Manohar R, Modha DS.

Science. 2014 Aug 8;345(6197):668-73. doi: 10.1126/science.1254642. Epub 2014 Aug 7.

45.

Considerations for non-clinical safety studies of therapeutic peptide vaccines.

Matsumoto M, Komatsu S, Tsuchimoto M, Matsui H, Watanabe K, Nakamura K, Amakasu K, Ito K, Fueki O, Sawada J, Maki K, Onodera H.

Regul Toxicol Pharmacol. 2014 Oct;70(1):254-60. doi: 10.1016/j.yrtph.2014.06.029. Epub 2014 Jul 17.

PMID:
25042360
46.

A case of pathology-proven neuromyelitis optica spectrum disorder with Sjögren syndrome manifesting aphasia and apraxia due to a localized cerebral white matter lesion.

Sawada J, Orimoto R, Misu T, Katayama T, Aizawa H, Asanome A, Takahashi K, Saito T, Anei R, Kamada K, Miyokawa N, Takahashi T, Fujihara K, Hasebe N.

Mult Scler. 2014 Sep;20(10):1413-6. doi: 10.1177/1352458514540834. Epub 2014 Jul 1.

PMID:
24986696
47.

Kinesin spindle protein inhibitors with diaryl amine scaffolds: crystal packing analysis for improved aqueous solubility.

Takeuchi T, Oishi S, Kaneda M, Ohno H, Nakamura S, Nakanishi I, Yamane M, Sawada J, Asai A, Fujii N.

ACS Med Chem Lett. 2014 Mar 10;5(5):566-71. doi: 10.1021/ml500016j. eCollection 2014 May 8.

48.

Optimization of diaryl amine derivatives as kinesin spindle protein inhibitors.

Takeuchi T, Oishi S, Kaneda M, Misu R, Ohno H, Sawada J, Asai A, Nakamura S, Nakanishi I, Fujii N.

Bioorg Med Chem. 2014 Jun 15;22(12):3171-9. doi: 10.1016/j.bmc.2014.04.008. Epub 2014 Apr 13.

PMID:
24794744
49.

[Reversible hepatic myelopathy: a case report].

Hirozawa D, Fukada K, Yaegaki T, Hoshi T, Sawada J, Hazama T.

Rinsho Shinkeigaku. 2014;54(3):223-6. Japanese.

PMID:
24705837
50.

Cerebral microbleeds and asymptomatic cerebral infarctions in patients with atrial fibrillation.

Saito T, Kawamura Y, Tanabe Y, Asanome A, Takahashi K, Sawada J, Katayama T, Sato N, Aizawa H, Hasebe N.

J Stroke Cerebrovasc Dis. 2014 Jul;23(6):1616-22. doi: 10.1016/j.jstrokecerebrovasdis.2014.01.005. Epub 2014 Mar 27.

PMID:
24680089

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