Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 411

1.

Editorial for "What can clinical findings tell us about the neurobiology of schizophrenia? Revisited".

Sakurai T, Sawa A.

Neurobiol Dis. 2019 Jul 9:104521. doi: 10.1016/j.nbd.2019.104521. [Epub ahead of print] No abstract available.

PMID:
31299219
2.

The transcriptome landscape associated with Disrupted-in-Schizophrenia-1 locus impairment in early development and adulthood.

Yang K, Kondo MA, Jaaro-Peled H, Cash-Padgett T, Kano SI, Ishizuka K, Pevsner J, Tomoda T, Sawa A, Niwa M.

Schizophr Res. 2019 Jun 13. pii: S0920-9964(19)30209-9. doi: 10.1016/j.schres.2019.05.032. [Epub ahead of print]

PMID:
31204062
3.

Assessing Reality Testing in Mice Through Dopamine-Dependent Associatively Evoked Processing of Absent Gustatory Stimuli.

Fry BR, Russell N, Gifford R, Robles CF, Manning CE, Sawa A, Niwa M, Johnson AW.

Schizophr Bull. 2019 May 31. pii: sbz043. doi: 10.1093/schbul/sbz043. [Epub ahead of print]

PMID:
31150554
4.

An in-silico approach for discovery of microRNA-TF regulation of DISC1 interactome mediating neuronal migration.

John JP, Thirunavukkarasu P, Ishizuka K, Parekh P, Sawa A.

NPJ Syst Biol Appl. 2019 May 7;5:17. doi: 10.1038/s41540-019-0094-3. eCollection 2019.

5.

Increased Protein Insolubility in Brains From a Subset of Patients With Schizophrenia.

Nucifora LG, MacDonald ML, Lee BJ, Peters ME, Norris AL, Orsburn BC, Yang K, Gleason K, Margolis RL, Pevsner J, Tamminga CA, Sweet RA, Ross CA, Sawa A, Nucifora FC Jr.

Am J Psychiatry. 2019 May 6:appiajp201918070864. doi: 10.1176/appi.ajp.2019.18070864. [Epub ahead of print]

PMID:
31055969
6.

Relationship between neuropsychological behavior and brain white matter in first-episode psychosis.

Faria AV, Crawford J, Ye C, Hsu J, Kenkare A, Schretlen D, Sawa A.

Schizophr Res. 2019 Jun;208:49-54. doi: 10.1016/j.schres.2019.04.010. Epub 2019 Apr 13.

PMID:
30987924
7.

Influence of poly(I:C) variability on thermoregulation, immune responses and pregnancy outcomes in mouse models of maternal immune activation.

Mueller FS, Richetto J, Hayes LN, Zambon A, Pollak DD, Sawa A, Meyer U, Weber-Stadlbauer U.

Brain Behav Immun. 2019 Apr 10. pii: S0889-1591(19)30121-7. doi: 10.1016/j.bbi.2019.04.019. [Epub ahead of print]

PMID:
30980948
8.

Silicon waveguide optical modulator driven by metal-insulator transition of vanadium dioxide cladding layer.

Shibuya K, Atsumi Y, Yoshida T, Sakakibara Y, Mori M, Sawa A.

Opt Express. 2019 Feb 18;27(4):4147-4156. doi: 10.1364/OE.27.004147.

PMID:
30876035
9.

A methodology for discovering novel brain-relevant peptides: Combination of ribosome profiling and peptidomics.

Tharakan R, Kreimer S, Ubaida-Mohien C, Lavoie J, Olexiouk V, Menschaert G, Ingolia NT, Cole RN, Ishizuka K, Sawa A, Nucifora LG.

Neurosci Res. 2019 Mar 9. pii: S0168-0102(18)30722-3. doi: 10.1016/j.neures.2019.02.006. [Epub ahead of print]

PMID:
30862443
10.

Causal Inference on Pathophysiological Mediators in Psychiatry.

Namkung H, Lee BJ, Sawa A.

Cold Spring Harb Symp Quant Biol. 2019 Mar 8. pii: 037655. doi: 10.1101/sqb.2018.83.037655. [Epub ahead of print]

PMID:
30850434
11.

Adolescent psychosocial stress enhances sensitization to cocaine exposure in genetically vulnerable mice.

Hikida T, Morita M, Kuroiwa M, Macpherson T, Shuto T, Sotogaku N, Niwa M, Sawa A, Nishi A.

Neurosci Res. 2019 Mar 1. pii: S0168-0102(19)30021-5. doi: 10.1016/j.neures.2019.02.007. [Epub ahead of print]

PMID:
30831136
12.

Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation.

Kano SI, Choi EY, Dohi E, Agarwal S, Chang DJ, Wilson AM, Lo BD, Rose IVL, Gonzalez S, Imai T, Sawa A.

Sci Signal. 2019 Feb 19;12(569). pii: eaar2124. doi: 10.1126/scisignal.aar2124.

PMID:
30783009
13.

The glutathione cycle shapes synaptic glutamate activity.

Sedlak TW, Paul BD, Parker GM, Hester LD, Snowman AM, Taniguchi Y, Kamiya A, Snyder SH, Sawa A.

Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2701-2706. doi: 10.1073/pnas.1817885116. Epub 2019 Jan 28.

PMID:
30692251
14.

Neurometabolic and functional connectivity basis of prosocial behavior in early adolescence.

Okada N, Yahata N, Koshiyama D, Morita K, Sawada K, Kanata S, Fujikawa S, Sugimoto N, Toriyama R, Masaoka M, Koike S, Araki T, Kano Y, Endo K, Yamasaki S, Ando S, Nishida A, Hiraiwa-Hasegawa M, Edden RAE, Barker PB, Sawa A, Kasai K.

Sci Rep. 2019 Jan 24;9(1):732. doi: 10.1038/s41598-018-38355-z.

15.

DISC1 and Its Protein Interactomes for Mental Function.

Sawa A.

Biol Psychiatry. 2019 Feb 15;85(4):283-284. doi: 10.1016/j.biopsych.2018.12.011. No abstract available.

PMID:
30665501
16.

Assessing Brain Metabolism With 7-T Proton Magnetic Resonance Spectroscopy in Patients With First-Episode Psychosis.

Wang AM, Pradhan S, Coughlin JM, Trivedi A, DuBois SL, Crawford JL, Sedlak TW, Nucifora FC Jr, Nestadt G, Nucifora LG, Schretlen DJ, Sawa A, Barker PB.

JAMA Psychiatry. 2019 Jan 9. doi: 10.1001/jamapsychiatry.2018.3637. [Epub ahead of print]

PMID:
30624573
17.

The availability of the α7 nicotinic acetylcholine receptor in recent-onset psychosis: a study using 18F-ASEM PET.

Coughlin J, Du Y, Crawford JL, Rubin LH, Behnam Azad B, Lesniak WG, Horti AG, Schretlen DJ, Sawa A, Pomper MG.

J Nucl Med. 2018 Dec 20. pii: jnumed.118.213686. doi: 10.2967/jnumed.118.213686. [Epub ahead of print]

PMID:
30573639
18.

Contributions of olfactory and neuropsychological assessment to the diagnosis of first-episode schizophrenia.

Kamath V, Crawford J, DuBois S, Nucifora FC, Nestadt G, Sawa A, Schretlen D.

Neuropsychology. 2019 Feb;33(2):203-211. doi: 10.1037/neu0000502. Epub 2018 Nov 26.

PMID:
30475048
19.

Probing ultrafast spin-relaxation and precession dynamics in a cuprate Mott insulator with seven-femtosecond optical pulses.

Miyamoto T, Matsui Y, Terashige T, Morimoto T, Sono N, Yada H, Ishihara S, Watanabe Y, Adachi S, Ito T, Oka K, Sawa A, Okamoto H.

Nat Commun. 2018 Sep 26;9(1):3948. doi: 10.1038/s41467-018-06312-z.

20.

Treatment resistant schizophrenia: Clinical, biological, and therapeutic perspectives.

Nucifora FC Jr, Woznica E, Lee BJ, Cascella N, Sawa A.

Neurobiol Dis. 2018 Aug 29. pii: S0969-9961(18)30494-7. doi: 10.1016/j.nbd.2018.08.016. [Epub ahead of print] Review.

PMID:
30170114
21.

Host-parasite interaction associated with major mental illness.

Kano SI, Hodgkinson CA, Jones-Brando L, Eastwood S, Ishizuka K, Niwa M, Choi EY, Chang DJ, Chen Y, Velivela SD, Leister F, Wood J, Chowdari K, Ducci F, Caycedo DA, Heinz E, Newman ER, Cascella N, Mortensen PB, Zandi PP, Dickerson F, Nimgaonkar V, Goldman D, Harrison PJ, Yolken RH, Sawa A.

Mol Psychiatry. 2018 Aug 20. doi: 10.1038/s41380-018-0217-z. [Epub ahead of print]

22.

A mouse model of 22q11.2 deletions: Molecular and behavioral signatures of Parkinson's disease and schizophrenia.

Sumitomo A, Horike K, Hirai K, Butcher N, Boot E, Sakurai T, Nucifora FC Jr, Bassett AS, Sawa A, Tomoda T.

Sci Adv. 2018 Aug 15;4(8):eaar6637. doi: 10.1126/sciadv.aar6637. eCollection 2018 Aug.

23.

Preoperative diagnosis of a giant cell tumor of soft tissue arising from the breast by ultrasound-guided core needle biopsy.

Sawa A, Ikeda T, Ichioka E, Tsushima Y, Iguchi-Manaka A, Bando H, Kondo Y, Hara H.

J Med Ultrason (2001). 2019 Apr;46(2):257-261. doi: 10.1007/s10396-018-0891-0. Epub 2018 Jul 30.

PMID:
30062496
24.

Dominant-Negative DISC1 Alters the Dopaminergic Modulation of Inhibitory Interneurons in the Mouse Prefrontal Cortex.

Cardarelli RA, Martin R, Jaaro-Peled H, Sawa A, Powell EM, O'Donnell P.

Mol Neuropsychiatry. 2018 Jun;4(1):20-29. doi: 10.1159/000488030. Epub 2018 May 7.

25.

Intramammary Metastasis in a Patient with a History of Renal Cell Carcinoma: A Case Report.

Kitahara M, Hozumi Y, Asada R, Sawa A, Saito H, Iijima T.

Case Rep Oncol. 2018 May 29;11(2):318-322. doi: 10.1159/000489391. eCollection 2018 May-Aug.

26.

The Insula: An Underestimated Brain Area in Clinical Neuroscience, Psychiatry, and Neurology: (Trends in Neuroscience 40, 200-207, 2017).

Namkung H, Kim SH, Sawa A.

Trends Neurosci. 2018 Aug;41(8):551-554. doi: 10.1016/j.tins.2018.05.004. Epub 2018 Jun 9. No abstract available.

PMID:
29895478
27.

Ulk2 controls cortical excitatory-inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons.

Sumitomo A, Yukitake H, Hirai K, Horike K, Ueta K, Chung Y, Warabi E, Yanagawa T, Kitaoka S, Furuyashiki T, Narumiya S, Hirano T, Niwa M, Sibille E, Hikida T, Sakurai T, Ishizuka K, Sawa A, Tomoda T.

Hum Mol Genet. 2018 Sep 15;27(18):3165-3176. doi: 10.1093/hmg/ddy219.

PMID:
29893844
28.

Methylphenidate and Guanfacine Ameliorate ADHD-Like Phenotypes in Fez1-Deficient Mice.

Sumitomo A, Saka A, Ueta K, Horike K, Hirai K, Gamo NJ, Hikida T, Nakayama KI, Sawa A, Sakurai T, Tomoda T.

Mol Neuropsychiatry. 2018 May;3(4):223-233. doi: 10.1159/000488081. Epub 2018 Apr 26.

29.

Sulforaphane Augments Glutathione and Influences Brain Metabolites in Human Subjects: A Clinical Pilot Study.

Sedlak TW, Nucifora LG, Koga M, Shaffer LS, Higgs C, Tanaka T, Wang AM, Coughlin JM, Barker PB, Fahey JW, Sawa A.

Mol Neuropsychiatry. 2018 May;3(4):214-222. doi: 10.1159/000487639. Epub 2018 Apr 17.

30.

Multifaceted Translational Approach to Major Mental Illness.

Sawa A.

In: Nakao K, Minato N, Uemoto S, editors. Innovative Medicine: Basic Research and Development [Internet]. Tokyo: Springer; 2015.

31.

Developmental trajectories of brain maturation and behavior: Relevance to major mental illnesses.

Lockhart S, Sawa A, Niwa M.

J Pharmacol Sci. 2018 May;137(1):1-4. doi: 10.1016/j.jphs.2018.04.008. Epub 2018 May 3. Review.

32.

TAR DNA-Binding Protein 43 and Disrupted in Schizophrenia 1 Coaggregation Disrupts Dendritic Local Translation and Mental Function in Frontotemporal Lobar Degeneration.

Endo R, Takashima N, Nekooki-Machida Y, Komi Y, Hui KK, Takao M, Akatsu H, Murayama S, Sawa A, Tanaka M.

Biol Psychiatry. 2018 Oct 1;84(7):509-521. doi: 10.1016/j.biopsych.2018.03.008. Epub 2018 Mar 29.

PMID:
29752072
33.

Chitinase mRNA Levels Determined by QPCR in Crab-Eating Monkey (Macaca fascicularis) Tissues: Species-Specific Expression of Acidic Mammalian Chitinase and Chitotriosidase.

Uehara M, Tabata E, Ishii K, Sawa A, Ohno M, Sakaguchi M, Matoska V, Bauer PO, Oyama F.

Genes (Basel). 2018 May 9;9(5). pii: E244. doi: 10.3390/genes9050244.

34.

Lithium-associated transcriptional regulation of CRMP1 in patient-derived olfactory neurons and symptom changes in bipolar disorder.

McLean CK, Narayan S, Lin SY, Rai N, Chung Y, Hipolito MS, Cascella NG, Nurnberger JI Jr, Ishizuka K, Sawa AS, Nwulia EA.

Transl Psychiatry. 2018 Apr 18;8(1):81. doi: 10.1038/s41398-018-0126-6.

35.

Early-onset epileptic encephalopathy and severe developmental delay in an association with de novo double mutations in NF1 and MAGEL2.

Akamine S, Sagata N, Sakai Y, Kato TA, Nakahara T, Matsushita Y, Togao O, Hiwatashi A, Sanefuji M, Ishizaki Y, Torisu H, Saitsu H, Matsumoto N, Hara T, Sawa A, Kano S, Furue M, Kanba S, Shaw CA, Ohga S.

Epilepsia Open. 2017 Nov 23;3(1):81-85. doi: 10.1002/epi4.12085. eCollection 2018 Mar.

36.

Brain PET Imaging of α7-nAChR with [18F]ASEM: Reproducibility, Occupancy, Receptor Density, and Changes in Schizophrenia.

Wong DF, Kuwabara H, Horti AG, Roberts JM, Nandi A, Cascella N, Brasic J, Weerts EM, Kitzmiller K, Phan JA, Gapasin L, Sawa A, Valentine H, Wand G, Mishra C, George N, McDonald M, Lesniak W, Holt DP, Azad BB, Dannals RF, Kem W, Freedman R, Gjedde A.

Int J Neuropsychopharmacol. 2018 Jul 1;21(7):656-667. doi: 10.1093/ijnp/pyy021.

37.

Dynamic Changes of the Mitochondria in Psychiatric Illnesses: New Mechanistic Insights From Human Neuronal Models.

Srivastava R, Faust T, Ramos A, Ishizuka K, Sawa A.

Biol Psychiatry. 2018 May 1;83(9):751-760. doi: 10.1016/j.biopsych.2018.01.007. Epub 2018 Jan 17. Review.

38.

Decoupling of Brain Temperature and Glutamate in Recent Onset of Schizophrenia: A 7T Proton Magnetic Resonance Spectroscopy Study.

Posporelis S, Coughlin JM, Marsman A, Pradhan S, Tanaka T, Wang H, Varvaris M, Ward R, Higgs C, Edwards JA, Ford CN, Kim PK, Lloyd AM, Edden RAE, Schretlen DJ, Cascella NG, Barker PB, Sawa A.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Mar;3(3):248-254. doi: 10.1016/j.bpsc.2017.04.003. Epub 2017 Apr 21.

39.

[11C](R)-Rolipram positron emission tomography detects DISC1 inhibition of phosphodiesterase type 4 in live Disc1 locus-impaired mice.

Ooms M, Tsujikawa T, Lohith TG, Mabins SN, Zoghbi SS, Sumitomo A, Jaaro-Peled H, Kimura Y, Telu S, Pike VW, Tomoda T, Innis RB, Sawa A, Fujita M.

J Cereb Blood Flow Metab. 2019 Jul;39(7):1306-1313. doi: 10.1177/0271678X18758997. Epub 2018 Feb 12.

PMID:
29430995
40.

Translocator protein (TSPO) and stress cascades in mouse models of psychosis with inflammatory disturbances.

Fukudome D, Hayes LN, Faust TE, Foss CA, Kondo MA, Lee BJ, Saito A, Kano SI, Coughlin JM, Kamiya A, Pomper MG, Sawa A, Niwa M.

Schizophr Res. 2018 Feb 2. pii: S0920-9964(18)30035-5. doi: 10.1016/j.schres.2018.01.015. [Epub ahead of print]

PMID:
29398205
41.

Approaches to neuromodulation for schizophrenia.

Gault JM, Davis R, Cascella NG, Saks ER, Corripio-Collado I, Anderson WS, Olincy A, Thompson JA, Pomarol-Clotet E, Sawa A, Daskalakis ZJ, Lipsman N, Abosch A.

J Neurol Neurosurg Psychiatry. 2018 Jul;89(7):777-787. doi: 10.1136/jnnp-2017-316946. Epub 2017 Dec 14. Review.

PMID:
29242310
42.

DISC1 Modulates Neuronal Stress Responses by Gate-Keeping ER-Mitochondria Ca2+ Transfer through the MAM.

Park SJ, Lee SB, Suh Y, Kim SJ, Lee N, Hong JH, Park C, Woo Y, Ishizuka K, Kim JH, Berggren PO, Sawa A, Park SK.

Cell Rep. 2017 Dec 5;21(10):2748-2759. doi: 10.1016/j.celrep.2017.11.043.

43.

Reconceptualization of translocator protein as a biomarker of neuroinflammation in psychiatry.

Notter T, Coughlin JM, Sawa A, Meyer U.

Mol Psychiatry. 2018 Jan;23(1):36-47. doi: 10.1038/mp.2017.232. Epub 2017 Dec 5. Review.

PMID:
29203847
44.

Psychosis Beyond the 22q11.2 Deletion: Do Additional Genetic Factors Play a Role?

Goes FS, Sawa A.

Am J Psychiatry. 2017 Nov 1;174(11):1027-1029. doi: 10.1176/appi.ajp.2017.17080910. No abstract available.

PMID:
29088933
45.

Genetic interaction of DISC1 and Neurexin in the development of fruit fly glutamatergic synapses.

Pandey H, Bourahmoune K, Honda T, Honjo K, Kurita K, Sato T, Sawa A, Furukubo-Tokunaga K.

NPJ Schizophr. 2017 Oct 27;3(1):39. doi: 10.1038/s41537-017-0040-6.

46.

Dysregulated gene expressions of MEX3D, FOS and BCL2 in human induced-neuronal (iN) cells from NF1 patients: a pilot study.

Sagata N, Kato TA, Kano SI, Ohgidani M, Shimokawa N, Sato-Kasai M, Hayakawa K, Kuwano N, Wilson AM, Ishizuka K, Kato S, Nakahara T, Nakahara-Kido M, Setoyama D, Sakai Y, Ohga S, Furue M, Sawa A, Kanba S.

Sci Rep. 2017 Oct 24;7(1):13905. doi: 10.1038/s41598-017-14440-7.

47.

Olfactory Functioning in First-Episode Psychosis.

Kamath V, Lasutschinkow P, Ishizuka K, Sawa A.

Schizophr Bull. 2018 Apr 6;44(3):672-680. doi: 10.1093/schbul/sbx107.

48.

A Chemical Modulator of p53 Transactivation that Acts as a Radioprotective Agonist.

Morita A, Takahashi I, Sasatani M, Aoki S, Wang B, Ariyasu S, Tanaka K, Yamaguchi T, Sawa A, Nishi Y, Teraoka T, Ujita S, Kawate Y, Yanagawa C, Tanimoto K, Enomoto A, Nenoi M, Kamiya K, Nagata Y, Hosoi Y, Inaba T.

Mol Cancer Ther. 2018 Feb;17(2):432-442. doi: 10.1158/1535-7163.MCT-16-0554. Epub 2017 Sep 22.

49.

Dopamine D1 receptor subtype mediates acute stress-induced dendritic growth in excitatory neurons of the medial prefrontal cortex and contributes to suppression of stress susceptibility in mice.

Shinohara R, Taniguchi M, Ehrlich AT, Yokogawa K, Deguchi Y, Cherasse Y, Lazarus M, Urade Y, Ogawa A, Kitaoka S, Sawa A, Narumiya S, Furuyashiki T.

Mol Psychiatry. 2018 Aug;23(8):1717-1730. doi: 10.1038/mp.2017.177. Epub 2017 Sep 19.

PMID:
28924188
50.

Reduction of plasma glutathione in psychosis associated with schizophrenia and bipolar disorder in translational psychiatry.

Nucifora LG, Tanaka T, Hayes LN, Kim M, Lee BJ, Matsuda T, Nucifora FC Jr, Sedlak T, Mojtabai R, Eaton W, Sawa A.

Transl Psychiatry. 2017 Aug 22;7(8):e1215. doi: 10.1038/tp.2017.178.

Supplemental Content

Support Center