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Items: 22

1.

Synthesis and biological evaluation of triazol-4-ylphenyl-bearing histone deacetylase inhibitors as anticancer agents.

He R, Chen Y, Chen Y, Ougolkov AV, Zhang JS, Savoy DN, Billadeau DD, Kozikowski AP.

J Med Chem. 2010 Feb 11;53(3):1347-56. doi: 10.1021/jm901667k.

2.

A series of potent and selective, triazolylphenyl-based histone deacetylases inhibitors with activity against pancreatic cancer cells and Plasmodium falciparum.

Chen Y, Lopez-Sanchez M, Savoy DN, Billadeau DD, Dow GS, Kozikowski AP.

J Med Chem. 2008 Jun 26;51(12):3437-48. doi: 10.1021/jm701606b.

PMID:
18494463
3.

Chemistry, biology, and QSAR studies of substituted biaryl hydroxamates and mercaptoacetamides as HDAC inhibitors-nanomolar-potency inhibitors of pancreatic cancer cell growth.

Kozikowski AP, Chen Y, Gaysin AM, Savoy DN, Billadeau DD, Kim KH.

ChemMedChem. 2008 Mar;3(3):487-501. doi: 10.1002/cmdc.200700314.

4.

Increased dental caries in people with neurofibromatosis 1.

Tucker T, Birch P, Savoy DM, Friedman JM.

Clin Genet. 2007 Dec;72(6):524-7.

PMID:
18001351
5.

Implication of the folate-methionine metabolism pathways in susceptibility to follicular lymphomas.

Niclot S, Pruvot Q, Besson C, Savoy D, Macintyre E, Salles G, Brousse N, Varet B, Landais P, Taupin P, Junien C, Baudry-Bluteau D.

Blood. 2006 Jul 1;108(1):278-85. Epub 2006 Jan 12.

PMID:
16410450
6.

Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells.

Ougolkov AV, Fernandez-Zapico ME, Savoy DN, Urrutia RA, Billadeau DD.

Cancer Res. 2005 Mar 15;65(6):2076-81.

7.

Dynamin 2 regulates T cell activation by controlling actin polymerization at the immunological synapse.

Gomez TS, Hamann MJ, McCarney S, Savoy DN, Lubking CM, Heldebrant MP, Labno CM, McKean DJ, McNiven MA, Burkhardt JK, Billadeau DD.

Nat Immunol. 2005 Mar;6(3):261-70. Epub 2005 Feb 6.

PMID:
15696170
8.

Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis.

Fernandez-Zapico ME, Gonzalez-Paz NC, Weiss E, Savoy DN, Molina JR, Fonseca R, Smyrk TC, Chari ST, Urrutia R, Billadeau DD.

Cancer Cell. 2005 Jan;7(1):39-49.

9.

Differential regulation of TCR-mediated gene transcription by Vav family members.

Zakaria S, Gomez TS, Savoy DN, McAdam S, Turner M, Abraham RT, Billadeau DD.

J Exp Med. 2004 Feb 2;199(3):429-34.

10.

Protein kinase Calpha (PKCalpha) acts upstream of PKCtheta to activate IkappaB kinase and NF-kappaB in T lymphocytes.

Trushin SA, Pennington KN, Carmona EM, Asin S, Savoy DN, Billadeau DD, Paya CV.

Mol Cell Biol. 2003 Oct;23(19):7068-81.

11.

RhoG regulates gene expression and the actin cytoskeleton in lymphocytes.

Vigorito E, Billadeu DD, Savoy D, McAdam S, Doody G, Fort P, Turner M.

Oncogene. 2003 Jan 23;22(3):330-42.

PMID:
12545154
12.

Sun protection among parents and children at freshwater beaches.

Shoveller JA, Savoy DM, Roberts RE.

Can J Public Health. 2002 Mar-Apr;93(2):146-8.

PMID:
11963521
13.

A role for a RhoA/ROCK/LIM-kinase pathway in the regulation of cytotoxic lymphocytes.

Lou Z, Billadeau DD, Savoy DN, Schoon RA, Leibson PJ.

J Immunol. 2001 Nov 15;167(10):5749-57.

14.

Multiple acral fibromas in a patient with familial retinoblastoma: a cutaneous marker of tumour-suppressor gene germline mutation?

Dereure O, Savoy D, Doz F, Junien C, Guilhou JJ.

Br J Dermatol. 2000 Oct;143(4):856-9.

PMID:
11069472
15.
16.

Moving beyond information: evaluation of a nutrition education tool based on a theoretical model.

Ulmi S, McGowan P, Gray D, Savoy D.

Eur J Clin Nutr. 1999 May;53 Suppl 2:S49-53.

PMID:
10406437
17.

French myotonic dystrophy families show expansion of a CTG repeat in complete linkage disequilibrium with an intragenic 1 kb insertion.

Lavedan C, Hofmann-Radvanyi H, Boileau C, Bonaïti-Pellié C, Savoy D, Shelbourne P, Duros C, Rabes JP, Dehaupas I, Luce S, et al.

J Med Genet. 1994 Jan;31(1):33-6.

18.

Myotonic dystrophy: absence of CTG enlarged transcript in congenital forms, and low expression of the normal allele.

Hofmann-Radvanyi H, Lavedan C, Rabès JP, Savoy D, Duros C, Johnson K, Junien C.

Hum Mol Genet. 1993 Aug;2(8):1263-6.

PMID:
7691346
19.

Myotonic dystrophy: size- and sex-dependent dynamics of CTG meiotic instability, and somatic mosaicism.

Lavedan C, Hofmann-Radvanyi H, Shelbourne P, Rabes JP, Duros C, Savoy D, Dehaupas I, Luce S, Johnson K, Junien C.

Am J Hum Genet. 1993 May;52(5):875-83.

20.

NcoI RFLP at 19q13 identified by the DNA sequence pW119B (D19S169).

Lavedan C, Savoy D, Simon M, Wieringa B, Junien C.

Nucleic Acids Res. 1991 Oct 25;19(20):5804. No abstract available.

21.

Prenatal diagnosis of myotonic dystrophy using closely linked flanking markers.

Lavedan C, Hofmann H, Shelbourne P, Duros C, Savoy D, Johnson K, Junien C.

J Med Genet. 1991 Feb;28(2):89-91.

22.

Direct haplotyping by double digestion of PCR-amplified creatine kinase (CKMM): application to myotonic dystrophy diagnosis.

Lavedan C, Duros C, Savoy D, Leblond S, Bailly J, Korneluk R, Junien C.

Genomics. 1990 Dec;8(4):739-40. No abstract available.

PMID:
1980487

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