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Items: 1 to 50 of 88

1.

Community-Based Study of Celiac Disease Autoimmunity Progression in Adults.

Choung RS, Khaleghi S, Cartee AK, Marietta EV, Larson JJ, King KS, Savolainen O, Ross AB, Rajkumar SV, Camilleri MJ, Rubio-Tapia A, Murray JA.

Gastroenterology. 2019 Sep 24. pii: S0016-5085(19)41339-5. doi: 10.1053/j.gastro.2019.09.006. [Epub ahead of print]

PMID:
31560892
2.

Impact of demography on linked selection in two outcrossing Brassicaceae species.

Mattila TM, Laenen B, Horvath R, Hämälä T, Savolainen O, Slotte T.

Ecol Evol. 2019 Aug 13;9(17):9532-9545. doi: 10.1002/ece3.5463. eCollection 2019 Sep.

3.

Inflorescence shoot elongation, but not flower primordia formation, is photoperiodically regulated in Arabidopsis lyrata.

Kemi U, Leinonen PH, Savolainen O, Kuittinen H.

Ann Bot. 2019 Aug 2;124(1):91-102. doi: 10.1093/aob/mcz035.

PMID:
31321402
4.

Genomic patterns of local adaptation under gene flow in Arabidopsis lyrata.

Hämälä T, Savolainen O.

Mol Biol Evol. 2019 Jun 25. pii: msz149. doi: 10.1093/molbev/msz149. [Epub ahead of print]

PMID:
31236594
5.

Interlaboratory Coverage Test on Plant Food Bioactive Compounds and their Metabolites by Mass Spectrometry-Based Untargeted Metabolomics.

Koistinen VM, da Silva AB, Abrankó L, Low D, Villalba RG, Barberán FT, Landberg R, Savolainen O, Alvarez-Acero I, de Pascual-Teresa S, Van Poucke C, Almeida C, Petrásková L, Valentová K, Durand S, Wiczkowski W, Szawara-Nowak D, González-Domínguez R, Llorach R, Andrés-Lacueva C, Aura AM, Seppänen-Laakso T, Hanhineva K, Manach C, Bronze MR.

Metabolites. 2018 Aug 24;8(3). pii: E46. doi: 10.3390/metabo8030046.

6.

Local adaptation and ecological differentiation under selection, migration, and drift in Arabidopsis lyrata.

Hämälä T, Mattila TM, Savolainen O.

Evolution. 2018 May 9. doi: 10.1111/evo.13502. [Epub ahead of print]

PMID:
29741234
7.

Scots pine aminopropyltransferases shed new light on evolution of the polyamine biosynthesis pathway in seed plants.

Vuosku J, Karppinen K, Muilu-Mäkelä R, Kusano T, Sagor GHM, Avia K, Alakärppä E, Kestilä J, Suokas M, Nickolov K, Hamberg L, Savolainen O, Häggman H, Sarjala T.

Ann Bot. 2018 May 11;121(6):1243-1256. doi: 10.1093/aob/mcy012.

8.

High rate of adaptive evolution in two widespread European pines.

Grivet D, Avia K, Vaattovaara A, Eckert AJ, Neale DB, Savolainen O, González-Martínez SC.

Mol Ecol. 2017 Dec;26(24):6857-6870. doi: 10.1111/mec.14402. Epub 2017 Dec 2.

PMID:
29110402
9.

Genome-Wide Analysis of Colonization History and Concomitant Selection in Arabidopsis lyrata.

Mattila TM, Tyrmi J, Pyhäjärvi T, Savolainen O.

Mol Biol Evol. 2017 Oct 1;34(10):2665-2677. doi: 10.1093/molbev/msx193.

PMID:
28957505
10.

Biomarkers of food intake and nutrient status are associated with glucose tolerance status and development of type 2 diabetes in older Swedish women.

Savolainen O, Lind MV, Bergström G, Fagerberg B, Sandberg AS, Ross A.

Am J Clin Nutr. 2017 Nov;106(5):1302-1310. doi: 10.3945/ajcn.117.152850. Epub 2017 Sep 13.

PMID:
28903960
11.

Extracts of Equisetum giganteum L and Copaifera reticulate Ducke show strong antiviral activity against the sexually transmitted pathogen herpes simplex virus type 2.

Churqui MP, Lind L, Thörn K, Svensson A, Savolainen O, Aranda KT, Eriksson K.

J Ethnopharmacol. 2018 Jan 10;210:192-197. doi: 10.1016/j.jep.2017.08.010. Epub 2017 Aug 12.

PMID:
28807852
12.

Biomarkers for predicting type 2 diabetes development-Can metabolomics improve on existing biomarkers?

Savolainen O, Fagerberg B, Vendelbo Lind M, Sandberg AS, Ross AB, Bergström G.

PLoS One. 2017 Jul 10;12(7):e0177738. doi: 10.1371/journal.pone.0177738. eCollection 2017.

13.

Quantification of benzoxazinoids and their metabolites in Nordic breads.

Dihm K, Vendelbo Lind M, Sundén H, Ross A, Savolainen O.

Food Chem. 2017 Nov 15;235:7-13. doi: 10.1016/j.foodchem.2017.05.007. Epub 2017 May 4.

PMID:
28554649
14.

Role of seed germination in adaptation and reproductive isolation in Arabidopsis lyrata.

Hämälä T, Mattila TM, Leinonen PH, Kuittinen H, Savolainen O.

Mol Ecol. 2017 Jul;26(13):3484-3496. doi: 10.1111/mec.14135. Epub 2017 May 5.

PMID:
28393414
15.

Splenic Immune Response Is Down-Regulated in C57BL/6J Mice Fed Eicosapentaenoic Acid and Docosahexaenoic Acid Enriched High Fat Diet.

Soni NK, Ross AB, Scheers N, Savolainen OI, Nookaew I, Gabrielsson BG, Sandberg AS.

Nutrients. 2017 Jan 10;9(1). pii: E50. doi: 10.3390/nu9010050.

16.

The Efficiency of Sclerotherapy in the Treatment of Vascular Malformations: A Retrospective Study of 63 Patients.

Veräjänkorva E, Rautio R, Giordano S, Koskivuo I, Savolainen O.

Plast Surg Int. 2016;2016:2809152. doi: 10.1155/2016/2809152. Epub 2016 Dec 15.

17.

Genetic heterogeneity underlying variation in a locally adaptive clinal trait in Pinus sylvestris revealed by a Bayesian multipopulation analysis.

Kujala ST, Knürr T, Kärkkäinen K, Neale DB, Sillanpää MJ, Savolainen O.

Heredity (Edinb). 2017 May;118(5):413-423. doi: 10.1038/hdy.2016.115. Epub 2016 Nov 30.

18.

Identification and quantification of even and odd chained 5-n alkylresorcinols, branched chain-alkylresorcinols and methylalkylresorcinols in Quinoa (Chenopodium quinoa).

Ross AB, Svelander C, Karlsson G, Savolainen OI.

Food Chem. 2017 Apr 1;220:344-351. doi: 10.1016/j.foodchem.2016.10.020. Epub 2016 Oct 5.

PMID:
27855910
19.

Herring and chicken/pork meals lead to differences in plasma levels of TCA intermediates and arginine metabolites in overweight and obese men and women.

Vincent A, Savolainen OI, Sen P, Carlsson NG, Almgren A, Lindqvist H, Lind MV, Undeland I, Sandberg AS, Ross AB.

Mol Nutr Food Res. 2017 Mar;61(3). doi: 10.1002/mnfr.201600400. Epub 2016 Nov 28.

PMID:
27801550
20.

Importance of incomplete lineage sorting and introgression in the origin of shared genetic variation between two closely related pines with overlapping distributions.

Zhou Y, Duvaux L, Ren G, Zhang L, Savolainen O, Liu J.

Heredity (Edinb). 2017 Mar;118(3):211-220. doi: 10.1038/hdy.2016.72. Epub 2016 Sep 21.

21.

Genomics: Geography matters for Arabidopsis.

Savolainen O, Lascoux M.

Nature. 2016 Sep 15;537(7620):314-315. doi: 10.1038/nature19466. Epub 2016 Sep 7. No abstract available.

PMID:
27602515
22.

Eicosapentaenoic and Docosahexaenoic Acid-Enriched High Fat Diet Delays Skeletal Muscle Degradation in Mice.

Soni NK, Ross AB, Scheers N, Savolainen OI, Nookaew I, Gabrielsson BG, Sandberg AS.

Nutrients. 2016 Sep 3;8(9). pii: E543. doi: 10.3390/nu8090543.

23.

The use of mass spectrometry for analysing metabolite biomarkers in epidemiology: methodological and statistical considerations for application to large numbers of biological samples.

Lind MV, Savolainen OI, Ross AB.

Eur J Epidemiol. 2016 Aug;31(8):717-33. doi: 10.1007/s10654-016-0166-2. Epub 2016 May 26. Review.

PMID:
27230258
24.

A high-throughput method for liquid chromatography-tandem mass spectrometry determination of plasma alkylresorcinols, biomarkers of whole grain wheat and rye intake.

Ross AB, Svelander C, Savolainen OI, Lind MV, Kirwan JP, Breton I, Godin JP, Sandberg AS.

Anal Biochem. 2016 Apr 15;499:1-7. doi: 10.1016/j.ab.2015.12.023. Epub 2016 Jan 28.

PMID:
26827992
25.

A Simultaneous Metabolic Profiling and Quantitative Multimetabolite Metabolomic Method for Human Plasma Using Gas-Chromatography Tandem Mass Spectrometry.

Savolainen OI, Sandberg AS, Ross AB.

J Proteome Res. 2016 Jan 4;15(1):259-65. doi: 10.1021/acs.jproteome.5b00790. Epub 2015 Nov 30.

PMID:
26615962
26.

Selection for population-specific adaptation shaped patterns of variation in the photoperiod pathway genes in Arabidopsis lyrata during post-glacial colonization.

Mattila TM, Aalto EA, Toivainen T, Niittyvuopio A, Piltonen S, Kuittinen H, Savolainen O.

Mol Ecol. 2016 Jan;25(2):581-97. doi: 10.1111/mec.13489. Epub 2016 Jan 18.

PMID:
26600237
27.

Glycosylated Benzoxazinoids Are Degraded during Fermentation of Wheat Bran.

Savolainen O, Pekkinen J, Katina K, Poutanen K, Hanhineva K.

J Agric Food Chem. 2015 Jul 1;63(25):5943-9. doi: 10.1021/acs.jafc.5b00879. Epub 2015 Jun 17.

PMID:
26040909
28.

Evolutionary conservation of cold-induced antisense RNAs of FLOWERING LOCUS C in Arabidopsis thaliana perennial relatives.

Castaings L, Bergonzi S, Albani MC, Kemi U, Savolainen O, Coupland G.

Nat Commun. 2014 Jul 17;5:4457. doi: 10.1038/ncomms5457.

29.

Association of FLOWERING LOCUS T/TERMINAL FLOWER 1-like gene FTL2 expression with growth rhythm in Scots pine (Pinus sylvestris).

Avia K, Kärkkäinen K, Lagercrantz U, Savolainen O.

New Phytol. 2014 Oct;204(1):159-70. doi: 10.1111/nph.12901. Epub 2014 Jun 18.

30.

Climatic adaptation and ecological divergence between two closely related pine species in Southeast China.

Zhou Y, Zhang L, Liu J, Wu G, Savolainen O.

Mol Ecol. 2014 Jul;23(14):3504-22. doi: 10.1111/mec.12830.

PMID:
24935279
31.

The postprandial plasma rye fingerprint includes benzoxazinoid-derived phenylacetamide sulfates.

Hanhineva K, Keski-Rahkonen P, Lappi J, Katina K, Pekkinen J, Savolainen O, Timonen O, Paananen J, Mykkänen H, Poutanen K.

J Nutr. 2014 Jul;144(7):1016-22. doi: 10.3945/jn.113.187237. Epub 2014 May 8.

PMID:
24812068
32.

The role of oxygen in the liquid fermentation of wheat bran.

Savolainen OI, Coda R, Suomi K, Katina K, Juvonen R, Hanhineva K, Poutanen K.

Food Chem. 2014 Jun 15;153:424-31. doi: 10.1016/j.foodchem.2013.12.062. Epub 2013 Dec 25.

PMID:
24491749
33.

A recent local sweep at the PHYA locus in the Northern European Spiterstulen population of Arabidopsis lyrata.

Toivainen T, Pyhäjärvi T, Niittyvuopio A, Savolainen O.

Mol Ecol. 2014 Mar;23(5):1040-52. doi: 10.1111/mec.12682. Epub 2014 Feb 19.

PMID:
24471518
34.

Disintegration of wheat aleurone structure has an impact on the bioavailability of phenolic compounds and other phytochemicals as evidenced by altered urinary metabolite profile of diet-induced obese mice.

Pekkinen J, Rosa NN, Savolainen OI, Keski-Rahkonen P, Mykkänen H, Poutanen K, Micard V, Hanhineva K.

Nutr Metab (Lond). 2014 Jan 2;11(1):1. doi: 10.1186/1743-7075-11-1.

35.

Ecological genomics of local adaptation.

Savolainen O, Lascoux M, Merilä J.

Nat Rev Genet. 2013 Nov;14(11):807-20. doi: 10.1038/nrg3522. Review.

PMID:
24136507
36.

Complex genetic effects on early vegetative development shape resource allocation differences between Arabidopsis lyrata populations.

Remington DL, Leinonen PH, Leppälä J, Savolainen O.

Genetics. 2013 Nov;195(3):1087-102. doi: 10.1534/genetics.113.151803. Epub 2013 Aug 26.

37.

Cytoplasmic male sterility contributes to hybrid incompatibility between subspecies of Arabidopsis lyrata.

Aalto EA, Koelewijn HP, Savolainen O.

G3 (Bethesda). 2013 Oct 3;3(10):1727-40. doi: 10.1534/g3.113.007815.

38.

Investigating incipient speciation in Arabidopsis lyrata from patterns of transmission ratio distortion.

Leppälä J, Bokma F, Savolainen O.

Genetics. 2013 Jul;194(3):697-708. doi: 10.1534/genetics.113.152561. Epub 2013 May 11.

39.

Genetic changes in flowering and morphology in response to adaptation to a high-latitude environment in Arabidopsis lyrata.

Quilot-Turion B, Leppälä J, Leinonen PH, Waldmann P, Savolainen O, Kuittinen H.

Ann Bot. 2013 May;111(5):957-68. doi: 10.1093/aob/mct055. Epub 2013 Mar 21.

40.

Potential for evolutionary responses to climate change - evidence from tree populations.

Alberto FJ, Aitken SN, Alía R, González-Martínez SC, Hänninen H, Kremer A, Lefèvre F, Lenormand T, Yeaman S, Whetten R, Savolainen O.

Glob Chang Biol. 2013 Jun;19(6):1645-61. doi: 10.1111/gcb.12181. Epub 2013 Apr 3. Review.

41.

Role of vernalization and of duplicated FLOWERING LOCUS C in the perennial Arabidopsis lyrata.

Kemi U, Niittyvuopio A, Toivainen T, Pasanen A, Quilot-Turion B, Holm K, Lagercrantz U, Savolainen O, Kuittinen H.

New Phytol. 2013 Jan;197(1):323-35. doi: 10.1111/j.1469-8137.2012.04378.x. Epub 2012 Oct 26.

42.

Towards decoding the conifer giga-genome.

Mackay J, Dean JF, Plomion C, Peterson DG, Cánovas FM, Pavy N, Ingvarsson PK, Savolainen O, Guevara MÁ, Fluch S, Vinceti B, Abarca D, Díaz-Sala C, Cervera MT.

Plant Mol Biol. 2012 Dec;80(6):555-69. doi: 10.1007/s11103-012-9961-7. Epub 2012 Sep 9. Review.

PMID:
22960864
43.

Time scales of divergence and speciation among natural populations and subspecies of Arabidopsis lyrata (Brassicaceae).

Pyhäjärvi T, Aalto E, Savolainen O.

Am J Bot. 2012 Aug;99(8):1314-22. doi: 10.3732/ajb.1100580. Epub 2012 Jul 20.

44.

Genetic basis of local adaptation and flowering time variation in Arabidopsis lyrata.

Leinonen PH, Remington DL, Leppälä J, Savolainen O.

Mol Ecol. 2013 Feb;22(3):709-23. doi: 10.1111/j.1365-294X.2012.05678.x. Epub 2012 Jun 25.

PMID:
22724431
45.

Evolution. The genomic basis of local climatic adaptation.

Savolainen O.

Science. 2011 Oct 7;334(6052):49-50. doi: 10.1126/science.1213788. No abstract available.

PMID:
21980101
46.

Nuclear-cytoplasmic interactions reduce male fertility in hybrids of Arabidopsis lyrata subspecies.

Leppälä J, Savolainen O.

Evolution. 2011 Oct;65(10):2959-72. doi: 10.1111/j.1558-5646.2011.01361.x. Epub 2011 Jun 20.

PMID:
21967435
47.

Adaptive potential of northernmost tree populations to climate change, with emphasis on Scots pine (Pinus sylvestris L.).

Savolainen O, Kujala ST, Sokol C, Pyhäjärvi T, Avia K, Knürr T, Kärkkäinen K, Hicks S.

J Hered. 2011 Sep-Oct;102(5):526-36. doi: 10.1093/jhered/esr056. Epub 2011 Jun 29.

PMID:
21715569
48.

Speciation history of three closely related pines Pinus mugo (T.), P. uliginosa (N.) and P. sylvestris (L.).

Wachowiak W, Palmé AE, Savolainen O.

Mol Ecol. 2011 Apr;20(8):1729-43. doi: 10.1111/j.1365-294X.2011.05037.x. Epub 2011 Mar 7.

PMID:
21375633
49.

Local adaptation, phenotypic differentiation, and hybrid fitness in diverged natural populations of Arabidopsis lyrata.

Leinonen PH, Remington DL, Savolainen O.

Evolution. 2011 Jan;65(1):90-107. doi: 10.1111/j.1558-5646.2010.01119.x. Epub 2010 Sep 25.

PMID:
20812972
50.

Investigating the effects of topography and clonality on genetic structuring within a large Norwegian population of Arabidopsis lyrata.

Lundemo S, Stenøien HK, Savolainen O.

Ann Bot. 2010 Aug;106(2):243-54. doi: 10.1093/aob/mcq102. Epub 2010 Jun 2.

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