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Items: 1 to 50 of 195

1.

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI.

Couto Alves A, De Silva NMG, Karhunen V, Sovio U, Das S, Taal HR, Warrington NM, Lewin AM, Kaakinen M, Cousminer DL, Thiering E, Timpson NJ, Bond TA, Lowry E, Brown CD, Estivill X, Lindi V, Bradfield JP, Geller F, Speed D, Coin LJM, Loh M, Barton SJ, Beilin LJ, Bisgaard H, Bønnelykke K, Alili R, Hatoum IJ, Schramm K, Cartwright R, Charles MA, Salerno V, Clément K, Claringbould AAJ; BIOS Consortium, van Duijn CM, Moltchanova E, Eriksson JG, Elks C, Feenstra B, Flexeder C, Franks S, Frayling TM, Freathy RM, Elliott P, Widén E, Hakonarson H, Hattersley AT, Rodriguez A, Banterle M, Heinrich J, Heude B, Holloway JW, Hofman A, Hyppönen E, Inskip H, Kaplan LM, Hedman AK, Läärä E, Prokisch H, Grallert H, Lakka TA, Lawlor DA, Melbye M, Ahluwalia TS, Marinelli M, Millwood IY, Palmer LJ, Pennell CE, Perry JR, Ring SM, Savolainen MJ, Rivadeneira F, Standl M, Sunyer J, Tiesler CMT, Uitterlinden AG, Schierding W, O'Sullivan JM, Prokopenko I, Herzig KH, Smith GD, O'Reilly P, Felix JF, Buxton JL, Blakemore AIF, Ong KK, Jaddoe VWV, Grant SFA, Sebert S, McCarthy MI, Järvelin MR; Early Growth Genetics (EGG) Consortium.

Sci Adv. 2019 Sep 4;5(9):eaaw3095. doi: 10.1126/sciadv.aaw3095. eCollection 2019 Sep.

2.

An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study.

Ulven SM, Holven KB, Rundblad A, Myhrstad MCW, Leder L, Dahlman I, Mello VD, Schwab U, Carlberg C, Pihlajamäki J, Hermansen K, Dragsted LO, Gunnarsdottir I, Cloetens L, Åkesson B, Rosqvist F, Hukkanen J, Herzig KH, Savolainen MJ, Risérus U, Thorsdottir I, Poutanen KS, Arner P, Uusitupa M, Kolehmainen M.

Nutrients. 2019 Dec 3;11(12). pii: E2932. doi: 10.3390/nu11122932.

3.

Quantitative assessment of betainized compounds and associations with dietary and metabolic biomarkers in the randomized study of the healthy Nordic diet (SYSDIET).

Tuomainen M, Kärkkäinen O, Leppänen J, Auriola S, Lehtonen M, Savolainen MJ, Hermansen K, Risérus U, Åkesson B, Thorsdottir I, Kolehmainen M, Uusitupa M, Poutanen K, Schwab U, Hanhineva K.

Am J Clin Nutr. 2019 Nov 1;110(5):1108-1118. doi: 10.1093/ajcn/nqz179.

PMID:
31504116
4.

Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with Metabolic Syndrome-A SYSDIET Sub-Study.

Myhrstad MCW, de Mello VD, Dahlman I, Kolehmainen M, Paananen J, Rundblad A, Carlberg C, Olstad OK, Pihlajamäki J, Holven KB, Hermansen K, Dragsted LO, Gunnarsdottir I, Cloetens L, Storm MU, Åkesson B, Rosqvist F, Hukkanen J, Herzig KH, Risérus U, Thorsdottir I, Poutanen KS, Savolainen MJ, Schwab U, Arner P, Uusitupa M, Ulven SM.

Mol Nutr Food Res. 2019 Apr 9:e1801405. doi: 10.1002/mnfr.201801405. [Epub ahead of print]

PMID:
30964598
5.

Prospective, randomized, double-blinded, placebo-controlled study on safety and tolerability of the krill powder product in overweight subjects with moderately elevated blood pressure.

Sarkkinen ES, Savolainen MJ, Taurio J, Marvola T, Bruheim I.

Lipids Health Dis. 2018 Dec 20;17(1):287. doi: 10.1186/s12944-018-0935-x.

6.

Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths.

Ruuth M, Nguyen SD, Vihervaara T, Hilvo M, Laajala TD, Kondadi PK, Gisterå A, Lähteenmäki H, Kittilä T, Huusko J, Uusitupa M, Schwab U, Savolainen MJ, Sinisalo J, Lokki ML, Nieminen MS, Jula A, Perola M, Ylä-Herttula S, Rudel L, Öörni A, Baumann M, Baruch A, Laaksonen R, Ketelhuth DFJ, Aittokallio T, Jauhiainen M, Käkelä R, Borén J, Williams KJ, Kovanen PT, Öörni K.

Eur Heart J. 2018 Jul 14;39(27):2562-2573. doi: 10.1093/eurheartj/ehy319.

7.

A randomized clinical trial of the effectiveness of a Web-based health behaviour change support system and group lifestyle counselling on body weight loss in overweight and obese subjects: 2-year outcomes.

Teeriniemi AM, Salonurmi T, Jokelainen T, Vähänikkilä H, Alahäivälä T, Karppinen P, Enwald H, Huotari ML, Laitinen J, Oinas-Kukkonen H, Savolainen MJ.

J Intern Med. 2018 Nov;284(5):534-545. doi: 10.1111/joim.12802. Epub 2018 Jul 4.

PMID:
29974563
8.

Opportunities and challenges of behavior change support systems for enhancing habit formation: A qualitative study.

Karppinen P, Oinas-Kukkonen H, Alahäivälä T, Jokelainen T, Teeriniemi AM, Salonurmi T, Savolainen MJ.

J Biomed Inform. 2018 Aug;84:82-92. doi: 10.1016/j.jbi.2018.06.012. Epub 2018 Jun 21.

9.

Ceramide stearic to palmitic acid ratio predicts incident diabetes.

Hilvo M, Salonurmi T, Havulinna AS, Kauhanen D, Pedersen ER, Tell GS, Meyer K, Teeriniemi AM, Laatikainen T, Jousilahti P, Savolainen MJ, Nygård O, Salomaa V, Laaksonen R.

Diabetologia. 2018 Jun;61(6):1424-1434. doi: 10.1007/s00125-018-4590-6. Epub 2018 Mar 15.

PMID:
29546476
10.

Impaired HDL2-mediated cholesterol efflux is associated with metabolic syndrome in families with early onset coronary heart disease and low HDL-cholesterol level.

Paavola T, Kuusisto S, Jauhiainen M, Kakko S, Kangas-Kontio T, Metso J, Soininen P, Ala-Korpela M, Bloigu R, Hannuksela ML, Savolainen MJ, Salonurmi T.

PLoS One. 2017 Feb 16;12(2):e0171993. doi: 10.1371/journal.pone.0171993. eCollection 2017.

11.

Elevated Levels of Plasma IgA Autoantibodies against Oxidized LDL Found in Proliferative Diabetic Retinopathy but Not in Nonproliferative Retinopathy.

Vavuli S, Salonurmi T, Loukovaara S, Nissinen AE, Savolainen MJ, Liinamaa MJ.

J Diabetes Res. 2016;2016:2614153. doi: 10.1155/2016/2614153. Epub 2016 Dec 20.

12.

Fto-Deficiency Affects the Gene and MicroRNA Expression Involved in Brown Adipogenesis and Browning of White Adipose Tissue in Mice.

Ronkainen J, Mondini E, Cinti F, Cinti S, Sebért S, Savolainen MJ, Salonurmi T.

Int J Mol Sci. 2016 Nov 7;17(11). pii: E1851.

13.

Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study.

Leder L, Kolehmainen M, Narverud I, Dahlman I, Myhrstad MC, de Mello VD, Paananen J, Carlberg C, Schwab U, Herzig KH, Cloetens L, Storm MU, Hukkanen J, Savolainen MJ, Rosqvist F, Hermansen K, Dragsted LO, Gunnarsdottir I, Thorsdottir I, Risérus U, Åkesson B, Thoresen M, Arner P, Poutanen KS, Uusitupa M, Holven KB, Ulven SM.

Genes Nutr. 2016 Mar 17;11:3. doi: 10.1186/s12263-016-0521-4. eCollection 2016.

14.

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

Kettunen J, Demirkan A, Würtz P, Draisma HH, Haller T, Rawal R, Vaarhorst A, Kangas AJ, Lyytikäinen LP, Pirinen M, Pool R, Sarin AP, Soininen P, Tukiainen T, Wang Q, Tiainen M, Tynkkynen T, Amin N, Zeller T, Beekman M, Deelen J, van Dijk KW, Esko T, Hottenga JJ, van Leeuwen EM, Lehtimäki T, Mihailov E, Rose RJ, de Craen AJ, Gieger C, Kähönen M, Perola M, Blankenberg S, Savolainen MJ, Verhoeven A, Viikari J, Willemsen G, Boomsma DI, van Duijn CM, Eriksson J, Jula A, Järvelin MR, Kaprio J, Metspalu A, Raitakari O, Salomaa V, Slagboom PE, Waldenberger M, Ripatti S, Ala-Korpela M.

Nat Commun. 2016 Mar 23;7:11122. doi: 10.1038/ncomms11122.

15.

A Healthy Nordic Diet Alters the Plasma Lipidomic Profile in Adults with Features of Metabolic Syndrome in a Multicenter Randomized Dietary Intervention.

Lankinen M, Schwab U, Kolehmainen M, Paananen J, Nygren H, Seppänen-Laakso T, Poutanen K, Hyötyläinen T, Risérus U, Savolainen MJ, Hukkanen J, Brader L, Marklund M, Rosqvist F, Hermansen K, Cloetens L, Önning G, Thorsdottir I, Gunnarsdottir I, Åkesson B, Dragsted LO, Uusitupa M, Orešič M.

J Nutr. 2015 Apr 1;146(4):662-672. doi: 10.3945/jn.115.220459.

PMID:
26962194
16.

The effect of pregnane X receptor agonists on postprandial incretin hormone secretion in rats and humans.

Hukkanen J, Rysa J, Makela KA, Herzig KH, Hakkola J, Savolainen MJ.

J Physiol Pharmacol. 2015 Dec;66(6):831-9.

17.

The fat mass and obesity-associated (FTO) gene variant rs9939609 predicts long-term incidence of cardiovascular disease and related death independent of the traditional risk factors.

Äijälä M, Ronkainen J, Huusko T, Malo E, Savolainen ER, Savolainen MJ, Salonurmi T, Bloigu R, Kesäniemi YA, Ukkola O.

Ann Med. 2015;47(8):655-63. doi: 10.3109/07853890.2015.1091088. Epub 2015 Nov 11.

PMID:
26555680
18.

The effect of atorvastatin treatment on serum oxysterol concentrations and cytochrome P450 3A4 activity.

Hukkanen J, Puurunen J, Hyötyläinen T, Savolainen MJ, Ruokonen A, Morin-Papunen L, Orešič M, Piltonen T, Tapanainen JS.

Br J Clin Pharmacol. 2015 Sep;80(3):473-9. doi: 10.1111/bcp.12701. Epub 2015 Jul 22.

19.

Mechanical Analysis of Ultrasound-Activated Pins and Resorbable Screws: Two Different Techniques to Fixate Osteosynthesis in Craniosynostosis Surgery.

Savolainen MJ, Ritvanen AG, Koljonen VS, Turunen MP, Hulkkonen HH, Vuorinen VH, Leikola JP.

J Craniofac Surg. 2015 Jun;26(4):1234-7. doi: 10.1097/SCS.0000000000001736.

PMID:
26080164
20.

Fat mass- and obesity-associated gene Fto affects the dietary response in mouse white adipose tissue.

Ronkainen J, Huusko TJ, Soininen R, Mondini E, Cinti F, Mäkelä KA, Kovalainen M, Herzig KH, Järvelin MR, Sebert S, Savolainen MJ, Salonurmi T.

Sci Rep. 2015 Mar 18;5:9233. doi: 10.1038/srep09233.

21.

Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome.

Kolehmainen M, Ulven SM, Paananen J, de Mello V, Schwab U, Carlberg C, Myhrstad M, Pihlajamäki J, Dungner E, Sjölin E, Gunnarsdottir I, Cloetens L, Landin-Olsson M, Akesson B, Rosqvist F, Hukkanen J, Herzig KH, Dragsted LO, Savolainen MJ, Brader L, Hermansen K, Risérus U, Thorsdottir I, Poutanen KS, Uusitupa M, Arner P, Dahlman I.

Am J Clin Nutr. 2015 Jan;101(1):228-39. doi: 10.3945/ajcn.114.092783. Epub 2014 Nov 19.

PMID:
25527767
22.

Epidemiology: disease associations and modulators of HDL-related biomarkers.

Savolainen MJ.

Handb Exp Pharmacol. 2015;224:259-83. doi: 10.1007/978-3-319-09665-0_7. Review.

PMID:
25522991
23.

Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change.

Würtz P, Wang Q, Kangas AJ, Richmond RC, Skarp J, Tiainen M, Tynkkynen T, Soininen P, Havulinna AS, Kaakinen M, Viikari JS, Savolainen MJ, Kähönen M, Lehtimäki T, Männistö S, Blankenberg S, Zeller T, Laitinen J, Pouta A, Mäntyselkä P, Vanhala M, Elliott P, Pietiläinen KH, Ripatti S, Salomaa V, Raitakari OT, Järvelin MR, Smith GD, Ala-Korpela M.

PLoS Med. 2014 Dec 9;11(12):e1001765. doi: 10.1371/journal.pmed.1001765. eCollection 2014 Dec.

24.

Whole grain rye intake, reflected by a biomarker, is associated with favorable blood lipid outcomes in subjects with the metabolic syndrome--a randomized study.

Magnusdottir OK, Landberg R, Gunnarsdottir I, Cloetens L, Åkesson B, Rosqvist F, Schwab U, Herzig KH, Hukkanen J, Savolainen MJ, Brader L, Hermansen K, Kolehmainen M, Poutanen K, Uusitupa M, Risérus U, Thorsdottir I.

PLoS One. 2014 Oct 23;9(10):e110827. doi: 10.1371/journal.pone.0110827. eCollection 2014.

25.

Life course structural equation model of the effects of prenatal and postnatal growth on adult blood pressure.

Kaakinen M, Sovio U, Hartikainen AL, Pouta A, Savolainen MJ, Herzig KH, Elliott P, De Stavola B, Läärä E, Järvelin MR.

J Epidemiol Community Health. 2014 Dec;68(12):1161-7. doi: 10.1136/jech-2013-203661. Epub 2014 Aug 8.

PMID:
25108017
26.

A dietary biomarker approach captures compliance and cardiometabolic effects of a healthy Nordic diet in individuals with metabolic syndrome.

Marklund M, Magnusdottir OK, Rosqvist F, Cloetens L, Landberg R, Kolehmainen M, Brader L, Hermansen K, Poutanen KS, Herzig KH, Hukkanen J, Savolainen MJ, Dragsted LO, Schwab U, Paananen J, Uusitupa M, Åkesson B, Thorsdottir I, Risérus U.

J Nutr. 2014 Oct;144(10):1642-9. doi: 10.3945/jn.114.193771. Epub 2014 Jul 30.

PMID:
25080537
27.

Specific collagen XVIII isoforms promote adipose tissue accrual via mechanisms determining adipocyte number and affect fat deposition.

Aikio M, Elamaa H, Vicente D, Izzi V, Kaur I, Seppinen L, Speedy HE, Kaminska D, Kuusisto S, Sormunen R, Heljasvaara R, Jones EL, Muilu M, Jauhiainen M, Pihlajamäki J, Savolainen MJ, Shoulders CC, Pihlajaniemi T.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):E3043-52. doi: 10.1073/pnas.1405879111. Epub 2014 Jul 14.

28.

Ethanol-induced impairment of polyamine homeostasis--a potential cause of neural tube defect and intrauterine growth restriction in fetal alcohol syndrome.

Haghighi Poodeh S, Alhonen L, Salonurmi T, Savolainen MJ.

Biochem Biophys Res Commun. 2014 Mar 28;446(1):173-8. doi: 10.1016/j.bbrc.2014.02.079. Epub 2014 Feb 25.

PMID:
24582559
29.

Effects of a healthy Nordic diet on plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome: a randomized, [corrected] controlled trial (SYSDIET).

Brader L, Rejnmark L, Carlberg C, Schwab U, Kolehmainen M, Rosqvist F, Cloetens L, Landin-Olsson M, Gunnarsdottir I, Poutanen KS, Herzig KH, Risérus U, Savolainen MJ, Thorsdottir I, Uusitupa M, Hermansen K.

Eur J Nutr. 2014 Jun;53(4):1123-34. doi: 10.1007/s00394-014-0674-3. Epub 2014 Feb 26. Erratum in: Eur J Nutr. 2014 Jun;53(4):1145.

PMID:
24570029
30.

Plasma alkylresorcinols C17:0/C21:0 ratio, a biomarker of relative whole-grain rye intake, is associated to insulin sensitivity: a randomized study.

Magnusdottir OK, Landberg R, Gunnarsdottir I, Cloetens L, Akesson B, Landin-Olsson M, Rosqvist F, Iggman D, Schwab U, Herzig KH, Savolainen MJ, Brader L, Hermansen K, Kolehmainen M, Poutanen K, Uusitupa M, Thorsdottir I, Risérus U.

Eur J Clin Nutr. 2014 Apr;68(4):453-8. doi: 10.1038/ejcn.2014.12. Epub 2014 Feb 19.

PMID:
24549027
31.

Statin therapy worsens insulin sensitivity in women with polycystic ovary syndrome (PCOS): a prospective, randomized, double-blind, placebo-controlled study.

Puurunen J, Piltonen T, Puukka K, Ruokonen A, Savolainen MJ, Bloigu R, Morin-Papunen L, Tapanainen JS.

J Clin Endocrinol Metab. 2013 Dec;98(12):4798-807. doi: 10.1210/jc.2013-2674. Epub 2013 Oct 23.

PMID:
24152688
32.

Meal frequencies modify the effect of common genetic variants on body mass index in adolescents of the northern Finland birth cohort 1986.

Jääskeläinen A, Schwab U, Kolehmainen M, Kaakinen M, Savolainen MJ, Froguel P, Cauchi S, Järvelin MR, Laitinen J.

PLoS One. 2013 Sep 10;8(9):e73802. doi: 10.1371/journal.pone.0073802. eCollection 2013.

33.

Plasma alkylresorcinols reflect important whole-grain components of a healthy Nordic diet.

Magnusdottir OK, Landberg R, Gunnarsdottir I, Cloetens L, Åkesson B, Önning G, Jonsdottir SE, Rosqvist F, Schwab U, Herzig KH, Savolainen MJ, Brader L, Hermansen K, Kolehmainen M, Poutanen K, Uusitupa M, Thorsdottir I, Risérus U.

J Nutr. 2013 Sep;143(9):1383-90. doi: 10.3945/jn.113.175588. Epub 2013 Jul 10.

PMID:
23843473
34.

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.

Fall T, Hägg S, Mägi R, Ploner A, Fischer K, Horikoshi M, Sarin AP, Thorleifsson G, Ladenvall C, Kals M, Kuningas M, Draisma HH, Ried JS, van Zuydam NR, Huikari V, Mangino M, Sonestedt E, Benyamin B, Nelson CP, Rivera NV, Kristiansson K, Shen HY, Havulinna AS, Dehghan A, Donnelly LA, Kaakinen M, Nuotio ML, Robertson N, de Bruijn RF, Ikram MA, Amin N, Balmforth AJ, Braund PS, Doney AS, Döring A, Elliott P, Esko T, Franco OH, Gretarsdottir S, Hartikainen AL, Heikkilä K, Herzig KH, Holm H, Hottenga JJ, Hyppönen E, Illig T, Isaacs A, Isomaa B, Karssen LC, Kettunen J, Koenig W, Kuulasmaa K, Laatikainen T, Laitinen J, Lindgren C, Lyssenko V, Läärä E, Rayner NW, Männistö S, Pouta A, Rathmann W, Rivadeneira F, Ruokonen A, Savolainen MJ, Sijbrands EJ, Small KS, Smit JH, Steinthorsdottir V, Syvänen AC, Taanila A, Tobin MD, Uitterlinden AG, Willems SM, Willemsen G, Witteman J, Perola M, Evans A, Ferrières J, Virtamo J, Kee F, Tregouet DA, Arveiler D, Amouyel P, Ferrario MM, Brambilla P, Hall AS, Heath AC, Madden PA, Martin NG, Montgomery GW, Whitfield JB, Jula A, Knekt P, Oostra B, van Duijn CM, Penninx BW, Smith GD, Kaprio J, Samani NJ, Gieger C, Peters A, Wichmann HE, Boomsma DI, de Geus EJ, Tuomi T, Power C, Hammond CJ, Spector TD, Lind L, Orho-Melander M, Palmer CN, Morris AD, Groop L, Järvelin MR, Salomaa V, Vartiainen E, Hofman A, Ripatti S, Metspalu A, Thorsteinsdottir U, Stefansson K, Pedersen NL, McCarthy MI, Ingelsson E, Prokopenko I; European Network for Genetic and Genomic Epidemiology (ENGAGE) consortium.

PLoS Med. 2013;10(6):e1001474. doi: 10.1371/journal.pmed.1001474. Epub 2013 Jun 25.

35.

Metabolic adaptation allows Amacr-deficient mice to remain symptom-free despite low levels of mature bile acids.

Selkälä EM, Kuusisto SM, Salonurmi T, Savolainen MJ, Jauhiainen M, Pirilä PL, Kvist AP, Conzelmann E, Schmitz W, Alexson SE, Kotti TJ, Hiltunen JK, Autio KJ.

Biochim Biophys Acta. 2013 Aug;1831(8):1335-43. doi: 10.1016/j.bbalip.2013.05.002. Epub 2013 May 13.

PMID:
23680781
36.

Pregnane X receptor agonists impair postprandial glucose tolerance.

Rysä J, Buler M, Savolainen MJ, Ruskoaho H, Hakkola J, Hukkanen J.

Clin Pharmacol Ther. 2013 Jun;93(6):556-63. doi: 10.1038/clpt.2013.48. Epub 2013 Mar 5.

PMID:
23588309
37.

Interleukin 8 promoter polymorphism predicts the initial response to bevacizumab treatment for exudative age-related macular degeneration.

Hautamäki A, Kivioja J, Vavuli S, Kakko S, Savolainen ER, Savolainen MJ, Liinamaa MJ, Seitsonen S, Onkamo P, Järvelä I, Immonen I.

Retina. 2013 Oct;33(9):1815-27. doi: 10.1097/IAE.0b013e318285cf92.

PMID:
23584701
38.

Effects of an isocaloric healthy Nordic diet on insulin sensitivity, lipid profile and inflammation markers in metabolic syndrome -- a randomized study (SYSDIET).

Uusitupa M, Hermansen K, Savolainen MJ, Schwab U, Kolehmainen M, Brader L, Mortensen LS, Cloetens L, Johansson-Persson A, Onning G, Landin-Olsson M, Herzig KH, Hukkanen J, Rosqvist F, Iggman D, Paananen J, Pulkki KJ, Siloaho M, Dragsted L, Barri T, Overvad K, Bach Knudsen KE, Hedemann MS, Arner P, Dahlman I, Borge GI, Baardseth P, Ulven SM, Gunnarsdottir I, Jónsdóttir S, Thorsdottir I, Orešič M, Poutanen KS, Risérus U, Akesson B.

J Intern Med. 2013 Jul;274(1):52-66. doi: 10.1111/joim.12044. Epub 2013 Mar 2.

39.

Long-term leisure-time physical activity and serum metabolome.

Kujala UM, Mäkinen VP, Heinonen I, Soininen P, Kangas AJ, Leskinen TH, Rahkila P, Würtz P, Kovanen V, Cheng S, Sipilä S, Hirvensalo M, Telama R, Tammelin T, Savolainen MJ, Pouta A, O'Reilly PF, Mäntyselkä P, Viikari J, Kähönen M, Lehtimäki T, Elliott P, Vanhala MJ, Raitakari OT, Järvelin MR, Kaprio J, Kainulainen H, Ala-Korpela M.

Circulation. 2013 Jan 22;127(3):340-8. doi: 10.1161/CIRCULATIONAHA.112.105551. Epub 2012 Dec 20.

PMID:
23258601
40.

High vitreous concentration of IL-6 and IL-8, but not of adhesion molecules in relation to plasma concentrations in proliferative diabetic retinopathy.

Koskela UE, Kuusisto SM, Nissinen AE, Savolainen MJ, Liinamaa MJ.

Ophthalmic Res. 2013;49(2):108-14. doi: 10.1159/000342977. Epub 2012 Dec 18.

PMID:
23257933
41.

Long telomeres in blood leukocytes are associated with a high risk of ascending aortic aneurysm.

Huusko TJ, Santaniemi M, Kakko S, Taskinen P, Ukkola O, Kesäniemi YA, Savolainen MJ, Salonurmi T.

PLoS One. 2012;7(11):e50828. doi: 10.1371/journal.pone.0050828. Epub 2012 Nov 29.

42.

Computationally estimated apolipoproteins B and A1 in predicting cardiovascular risk.

Raitakari OT, Mäkinen VP, McQueen MJ, Niemi J, Juonala M, Jauhiainen M, Salomaa V, Hannuksela ML, Savolainen MJ, Kesäniemi YA, Kovanen PT, Sundvall J, Solakivi T, Loo BM, Marniemi J, Hernesniemi J, Lehtimäki T, Kähönen M, Peltonen M, Leiviskä J, Jula A, Anand SS, Miller R, Yusuf S, Viikari JS, Ala-Korpela M.

Atherosclerosis. 2013 Jan;226(1):245-51. doi: 10.1016/j.atherosclerosis.2012.10.049. Epub 2012 Nov 2.

PMID:
23159013
43.

Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.

Inouye M, Ripatti S, Kettunen J, Lyytikäinen LP, Oksala N, Laurila PP, Kangas AJ, Soininen P, Savolainen MJ, Viikari J, Kähönen M, Perola M, Salomaa V, Raitakari O, Lehtimäki T, Taskinen MR, Järvelin MR, Ala-Korpela M, Palotie A, de Bakker PI.

PLoS Genet. 2012;8(8):e1002907. doi: 10.1371/journal.pgen.1002907. Epub 2012 Aug 16.

44.

Alcohol-induced premature permeability in mouse placenta-yolk sac barriers in vivo.

Haghighi Poodeh S, Salonurmi T, Nagy I, Koivunen P, Vuoristo J, Räsänen J, Sormunen R, Vainio S, Savolainen MJ.

Placenta. 2012 Oct;33(10):866-73. doi: 10.1016/j.placenta.2012.07.008. Epub 2012 Aug 9.

PMID:
22884851
45.

Mild cognitive impairment associates with concurrent decreases in serum cholesterol and cholesterol-related lipoprotein subclasses.

Tukiainen T, Jylänki P, Mäkinen VP, Gröhn O, Hallikainen M, Soininen H, Kivipelto M, Kaski K, Groop PH, Savolainen MJ, Pirttilä T, Soininen P, Ala-Korpela M.

J Nutr Health Aging. 2012 Jul;16(7):631-5.

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