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Items: 49

1.

Influence of Flavonoids on the Cytotoxic Activity of Mononuclear Blood Cells in Model Tests.

Babaskina LI, Litvinova TM, Babaskin DV, Kiselevsky MV, Savinova OV, Winter EA.

Open Access Maced J Med Sci. 2019 Jun 30;7(12):1900-1904. doi: 10.3889/oamjms.2019.331. eCollection 2019 Jun 30.

2.

Homoarginine Supplementation Prevents Left Ventricular Dilatation and Preserves Systolic Function in a Model of Coronary Artery Disease.

Rodionov RN, Begmatov H, Jarzebska N, Patel K, Mills MT, Ghani Z, Khakshour D, Tamboli P, Patel MN, Abdalla M, Assaf M, Bornstein SR, Millan JL, Bode-Böger SM, Martens-Lobenhoffer J, Weiss N, Savinova OV.

J Am Heart Assoc. 2019 Jul 16;8(14):e012486. doi: 10.1161/JAHA.119.012486. Epub 2019 Jul 15.

3.

Triiodothyronine Reduces Vascular Dysfunction Associated with Hypertension by Attenuating Protein Kinase G/Vasodilator-Stimulated Phosphoprotein Signaling.

Carrillo-Sepulveda MA, Panackal A, Maracheril R, Maddie N, Patel MN, Ojamaa K, Savinova OV, Gerdes AM.

J Pharmacol Exp Ther. 2019 Oct;371(1):88-94. doi: 10.1124/jpet.119.260471. Epub 2019 Jul 12.

PMID:
31300610
4.

Malformation of the Posterior Cerebellar Vermis Is a Common Neuroanatomical Phenotype of Genetically Engineered Mice on the C57BL/6 Background.

Cuoco JA, Esposito AW, Moriarty S, Tang Y, Seth S, Toia AR, Kampton EB, Mayr Y, Khan M, Khan MB, Mullen BR, Ackman JB, Siddiqi F, Wolfe JH, Savinova OV, Ramos RL.

Cerebellum. 2018 Apr;17(2):173-190. doi: 10.1007/s12311-017-0892-3.

5.

Overexpression of tissue-nonspecific alkaline phosphatase (TNAP) in endothelial cells accelerates coronary artery disease in a mouse model of familial hypercholesterolemia.

Romanelli F, Corbo A, Salehi M, Yadav MC, Salman S, Petrosian D, Rashidbaigi OJ, Chait J, Kuruvilla J, Plummer M, Radichev I, Margulies KB, Gerdes AM, Pinkerton AB, Millán JL, Savinov AY, Savinova OV.

PLoS One. 2017 Oct 12;12(10):e0186426. doi: 10.1371/journal.pone.0186426. eCollection 2017.

6.

Apolipoprotein A-I exchange is impaired in metabolic syndrome patients asymptomatic for diabetes and cardiovascular disease.

Borja MS, Hammerson B, Tang C, Savinova OV, Shearer GC, Oda MN.

PLoS One. 2017 Aug 2;12(8):e0182217. doi: 10.1371/journal.pone.0182217. eCollection 2017.

7.

Modified Low-Dose Triiodo-L-thyronine Therapy Safely Improves Function Following Myocardial Ischemia-Reperfusion Injury.

Rajagopalan V, Zhang Y, Pol C, Costello C, Seitter S, Lehto A, Savinova OV, Chen YF, Gerdes AM.

Front Physiol. 2017 Apr 12;8:225. doi: 10.3389/fphys.2017.00225. eCollection 2017.

8.

Transgenic Overexpression of Tissue-Nonspecific Alkaline Phosphatase (TNAP) in Vascular Endothelium Results in Generalized Arterial Calcification.

Savinov AY, Salehi M, Yadav MC, Radichev I, Millán JL, Savinova OV.

J Am Heart Assoc. 2015 Dec 16;4(12). pii: e002499. doi: 10.1161/JAHA.115.002499.

9.

Effects of niacin and omega-3 fatty acids on the apolipoproteins in overweight patients with elevated triglycerides and reduced HDL cholesterol.

Savinova OV, Fillaus K, Harris WS, Shearer GC.

Atherosclerosis. 2015 Jun;240(2):520-5. doi: 10.1016/j.atherosclerosis.2015.04.793. Epub 2015 Apr 22.

PMID:
25932792
10.

Reduced apolipoprotein glycosylation in patients with the metabolic syndrome.

Savinova OV, Fillaus K, Jing L, Harris WS, Shearer GC.

PLoS One. 2014 Aug 12;9(8):e104833. doi: 10.1371/journal.pone.0104833. eCollection 2014.

11.

Functionalization, cyclization and antiviral activity of A-secotriterpenoids.

Grishko VV, Galaiko NV, Tolmacheva IA, Kucherov II, Eremin VF, Boreko EI, Savinova OV, Slepukhin PA.

Eur J Med Chem. 2014 Aug 18;83:601-8. doi: 10.1016/j.ejmech.2013.12.058. Epub 2014 Jan 10.

PMID:
24997292
12.

[Synthesis and biological activity of 2,3-secotriterpene acid mono- and diamides].

Tolmacheva IA, Igosheva EV, Vikharev IuB, Grishko VV, Savinova OV, Boreko EI, Eremin VF.

Bioorg Khim. 2013 Mar-Apr;39(2):212-20. Russian.

PMID:
23964522
13.

Restoration of cardiac tissue thyroid hormone status in experimental hypothyroidism: a dose-response study in female rats.

Weltman NY, Ojamaa K, Savinova OV, Chen YF, Schlenker EH, Zucchi R, Saba A, Colligiani D, Pol CJ, Gerdes AM.

Endocrinology. 2013 Jul;154(7):2542-52. doi: 10.1210/en.2012-2087. Epub 2013 Apr 17.

14.

Regulation of gene expression with thyroid hormone in rats with myocardial infarction.

Chen YF, Pottala JV, Weltman NY, Ge X, Savinova OV, Gerdes AM.

PLoS One. 2012;7(8):e40161. doi: 10.1371/journal.pone.0040161. Epub 2012 Aug 1.

15.

Thyroid hormone induces sprouting angiogenesis in adult heart of hypothyroid mice through the PDGF-Akt pathway.

Chen J, Ortmeier SB, Savinova OV, Nareddy VB, Beyer AJ, Wang D, Gerdes AM.

J Cell Mol Med. 2012 Nov;16(11):2726-35. doi: 10.1111/j.1582-4934.2012.01593.x.

16.

Radical-regulating and antiviral properties of ascorbic acid and its derivatives.

Brinkevich SD, Boreko EI, Savinova OV, Pavlova NI, Shadyro OI.

Bioorg Med Chem Lett. 2012 Apr 1;22(7):2424-7. doi: 10.1016/j.bmcl.2012.02.022. Epub 2012 Feb 16.

PMID:
22390834
17.

Myocyte changes in heart failure.

Savinova OV, Gerdes AM.

Heart Fail Clin. 2012 Jan;8(1):1-6. doi: 10.1016/j.hfc.2011.08.004. Epub 2011 Oct 13. Review.

PMID:
22108722
18.

Fish oil -- how does it reduce plasma triglycerides?

Shearer GC, Savinova OV, Harris WS.

Biochim Biophys Acta. 2012 May;1821(5):843-51. doi: 10.1016/j.bbalip.2011.10.011. Epub 2011 Oct 25.

19.

Thyroid hormone promotes remodeling of coronary resistance vessels.

Savinova OV, Liu Y, Aasen GA, Mao K, Weltman NY, Nedich BL, Liang Q, Gerdes AM.

PLoS One. 2011;6(9):e25054. doi: 10.1371/journal.pone.0025054. Epub 2011 Sep 22.

20.

[New betulin derivatives in combination with rimantadine for inhibition of influenza virus reproduction].

Savinova OV, Pavlova NI, Boreko EI.

Antibiot Khimioter. 2009;54(5-6):16-20. Russian.

PMID:
20052912
21.

[Synthesis of dihydroquinopymaric acid conjugates with amino acids].

Flekhter OB, Smirnova IE, Tret'iakova EV, Tolstikov GA, Savinova OV, Boreko EI.

Bioorg Khim. 2009 May-Jun;35(3):424-30. Russian.

PMID:
19621059
22.

The Nfkb1 and Nfkb2 proteins p105 and p100 function as the core of high-molecular-weight heterogeneous complexes.

Savinova OV, Hoffmann A, Ghosh G.

Mol Cell. 2009 Jun 12;34(5):591-602. doi: 10.1016/j.molcel.2009.04.033.

23.

Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen- and cytokine-receptor signaling specificity.

Shih VF, Kearns JD, Basak S, Savinova OV, Ghosh G, Hoffmann A.

Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9619-24. doi: 10.1073/pnas.0812367106. Epub 2009 Jun 1.

24.

[Betulonic amides modified at the ring A by amino acids: synthesis and inhibition of influenza A virus reproduction].

Flekhter OB, Medvedeva NI, Tolstikov GA, Savinova OV, Boreko EI, Dolgushin FM.

Bioorg Khim. 2009 Jan-Feb;35(1):129-33. Russian.

PMID:
19377531
25.

Stabilization of RelB requires multidomain interactions with p100/p52.

Fusco AJ, Savinova OV, Talwar R, Kearns JD, Hoffmann A, Ghosh G.

J Biol Chem. 2008 May 2;283(18):12324-32. doi: 10.1074/jbc.M707898200. Epub 2008 Mar 4.

26.

The cyclosporine-A-sensitive mitochondrial permeability transition pore in winter wheat at a low temperature and under oxidative stress.

Pavlovskaya NS, Savinova OV, Grabel'nykh OI, Pobezhimova TP, Koroleva NA, Voinikov VK.

Dokl Biol Sci. 2007 Nov-Dec;417:446-8. No abstract available.

PMID:
18274487
27.

[Synthesis and antiviral activity of lupane triterpenoids with modified cycle E].

Flekhter OB, Medvedeva NI, Kukovinets OS, Spirikhin LV, Galkin EG, Galin FZ, Golovanov DG, Pavlova NI, Savinova OV, Boreko EI, Tolstikov GA.

Bioorg Khim. 2007 Nov-Dec;33(6):629-34. Russian.

PMID:
18173126
28.

Inducible nitric oxide synthase, Nos2, does not mediate optic neuropathy and retinopathy in the DBA/2J glaucoma model.

Libby RT, Howell GR, Pang IH, Savinova OV, Mehalow AK, Barter JW, Smith RS, Clark AF, John SW.

BMC Neurosci. 2007 Dec 19;8:108.

29.

Col4a1 mutation causes endoplasmic reticulum stress and genetically modifiable ocular dysgenesis.

Gould DB, Marchant JK, Savinova OV, Smith RS, John SW.

Hum Mol Genet. 2007 Apr 1;16(7):798-807. Epub 2007 Feb 22.

PMID:
17317786
30.

The 20S proteasome processes NF-kappaB1 p105 into p50 in a translation-independent manner.

Moorthy AK, Savinova OV, Ho JQ, Wang VY, Vu D, Ghosh G.

EMBO J. 2006 May 3;25(9):1945-56. Epub 2006 Apr 13.

31.

Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegeneration.

Libby RT, Anderson MG, Pang IH, Robinson ZH, Savinova OV, Cosma IM, Snow A, Wilson LA, Smith RS, Clark AF, John SW.

Vis Neurosci. 2005 Sep-Oct;22(5):637-48.

PMID:
16332275
32.

Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage.

Libby RT, Li Y, Savinova OV, Barter J, Smith RS, Nickells RW, John SW.

PLoS Genet. 2005 Jul;1(1):17-26. Epub 2005 Jul 25.

33.

Genetically increasing Myoc expression supports a necessary pathologic role of abnormal proteins in glaucoma.

Gould DB, Miceli-Libby L, Savinova OV, Torrado M, Tomarev SI, Smith RS, John SW.

Mol Cell Biol. 2004 Oct;24(20):9019-25.

34.

[Synthesis and antiviral activity of amides and conjugates of betulonic acid with amino acids].

Flekhter OB, Boreko EI, Tret'iakova EV, Pavlova NI, Baltina LA, Nikolaeva SN, Savinova OV, Eremin VF, Galin FZ, Tolstikov GA.

Bioorg Khim. 2004 Jan-Feb;30(1):89-98. Russian.

PMID:
15040309
35.

[Synthesis and antiviral activity of ureides and carbamates of betulinic acid and its derivatives].

Flekhter OB, Boreko EI, Nigmatullina LR, Tret'iakova EV, Pavlova NI, Baltina LA, Nikolaeva SN, Savinova OV, Galin FZ, Tolstikov GA.

Bioorg Khim. 2003 Nov-Dec;29(6):655-61. Russian.

PMID:
14743541
36.

Lupane triterpenes and derivatives with antiviral activity.

Baltina LA, Flekhter OB, Nigmatullina LR, Boreko EI, Pavlova NI, Nikolaeva SN, Savinova OV, Tolstikov GA.

Bioorg Med Chem Lett. 2003 Oct 20;13(20):3549-52.

PMID:
14505668
37.

[Synthesis and antiviral activity of hydrazides and substituted benzalhydrazides of betulinic acid and its derivatives].

Flekhter OB, Boreko EI, Nigmatullina LR, Pavlova NI, Nikolaeva SN, Savinova OV, Eremin VF, Baltina LA, Galin FZ, Tolstikov GA.

Bioorg Khim. 2003 May-Jun;29(3):326-32. Russian.

PMID:
12845810
38.

Antiviral activity of betulin, betulinic and betulonic acids against some enveloped and non-enveloped viruses.

Pavlova NI, Savinova OV, Nikolaeva SN, Boreko EI, Flekhter OB.

Fitoterapia. 2003 Jul;74(5):489-92.

PMID:
12837369
39.

By altering ocular immune privilege, bone marrow-derived cells pathogenically contribute to DBA/2J pigmentary glaucoma.

Mo JS, Anderson MG, Gregory M, Smith RS, Savinova OV, Serreze DV, Ksander BR, Streilein JW, John SW.

J Exp Med. 2003 May 19;197(10):1335-44.

40.

Modification of ocular defects in mouse developmental glaucoma models by tyrosinase.

Libby RT, Smith RS, Savinova OV, Zabaleta A, Martin JE, Gonzalez FJ, John SW.

Science. 2003 Mar 7;299(5612):1578-81.

41.

Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure.

Chang B, Smith RS, Peters M, Savinova OV, Hawes NL, Zabaleta A, Nusinowitz S, Martin JE, Davisson ML, Cepko CL, Hogan BL, John SW.

BMC Genet. 2001;2:18. Epub 2001 Nov 6.

42.

Targeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function.

Kim BS, Savinova OV, Reedy MV, Martin J, Lun Y, Gan L, Smith RS, Tomarev SI, John SW, Johnson RL.

Mol Cell Biol. 2001 Nov;21(22):7707-13.

43.

Intraocular pressure in genetically distinct mice: an update and strain survey.

Savinova OV, Sugiyama F, Martin JE, Tomarev SI, Paigen BJ, Smith RS, John SW.

BMC Genet. 2001;2:12. Epub 2001 Aug 9. Erratum in: BMC Genet. 2001;2(1):16..

44.

The mouse anterior chamber angle and trabecular meshwork develop without cell death.

Smith RS, Zabaleta A, Savinova OV, John SW.

BMC Dev Biol. 2001;1:3. Epub 2001 Feb 14.

45.

Genetic modification of glaucoma associated phenotypes between AKXD-28/Ty and DBA/2J mice.

Anderson MG, Smith RS, Savinova OV, Hawes NL, Chang B, Zabaleta A, Wilpan R, Heckenlively JR, Davisson M, John SW.

BMC Genet. 2001;2:1. Epub 2001 Jan 15.

46.

Haploinsufficiency of the transcription factors FOXC1 and FOXC2 results in aberrant ocular development.

Smith RS, Zabaleta A, Kume T, Savinova OV, Kidson SH, Martin JE, Nishimura DY, Alward WL, Hogan BL, John SW.

Hum Mol Genet. 2000 Apr 12;9(7):1021-32.

PMID:
10767326
47.

Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice.

John SW, Smith RS, Savinova OV, Hawes NL, Chang B, Turnbull D, Davisson M, Roderick TH, Heckenlively JR.

Invest Ophthalmol Vis Sci. 1998 May;39(6):951-62. Erratum in: Invest Ophthalmol Vis Sci 1998 Aug;39(9):1641.

PMID:
9579474
48.

Mouse natriuretic peptide receptor 3 gene maps to proximal chromosome 15.

Savinova OV, Matsukawa N, Smithies O, John SW.

Mamm Genome. 1997 Oct;8(10):788. No abstract available.

PMID:
9321481
49.

[Effective expression of the apolipoprotein A-I gene, transferred to growing human cells in vitro].

Kuryshev VIu, Drapchinskaia NL, Tsarapkina EV, Savinova OV, Vorob'ev EV, Dizhe EB, Denisenko AD, Perevozchikov AP.

Biull Eksp Biol Med. 1994 Nov;118(11):479-82. Russian. No abstract available.

PMID:
7534126

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