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Items: 35

1.

11β-Hydroxysteroid Dehydrogenase Type 1 Is Expressed in Neutrophils and Restrains an Inflammatory Response in Male Mice.

Coutinho AE, Kipari TM, Zhang Z, Esteves CL, Lucas CD, Gilmour JS, Webster SP, Walker BR, Hughes J, Savill JS, Seckl JR, Rossi AG, Chapman KE.

Endocrinology. 2016 Jul;157(7):2928-36. doi: 10.1210/en.2016-1118. Epub 2016 May 4.

2.

Changing glucocorticoid action: 11β-hydroxysteroid dehydrogenase type 1 in acute and chronic inflammation.

Chapman KE, Coutinho AE, Zhang Z, Kipari T, Savill JS, Seckl JR.

J Steroid Biochem Mol Biol. 2013 Sep;137:82-92. doi: 10.1016/j.jsbmb.2013.02.002. Epub 2013 Feb 19. Review.

3.

Mast cells express 11β-hydroxysteroid dehydrogenase type 1: a role in restraining mast cell degranulation.

Coutinho AE, Brown JK, Yang F, Brownstein DG, Gray M, Seckl JR, Savill JS, Chapman KE.

PLoS One. 2013;8(1):e54640. doi: 10.1371/journal.pone.0054640. Epub 2013 Jan 18.

4.

11β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis.

Kipari T, Hadoke PW, Iqbal J, Man TY, Miller E, Coutinho AE, Zhang Z, Sullivan KM, Mitic T, Livingstone DE, Schrecker C, Samuel K, White CI, Bouhlel MA, Chinetti-Gbaguidi G, Staels B, Andrew R, Walker BR, Savill JS, Chapman KE, Seckl JR.

FASEB J. 2013 Apr;27(4):1519-31. doi: 10.1096/fj.12-219105. Epub 2013 Jan 9.

5.

11β-Hydroxysteroid dehydrogenase type 1, but not type 2, deficiency worsens acute inflammation and experimental arthritis in mice.

Coutinho AE, Gray M, Brownstein DG, Salter DM, Sawatzky DA, Clay S, Gilmour JS, Seckl JR, Savill JS, Chapman KE.

Endocrinology. 2012 Jan;153(1):234-40. doi: 10.1210/en.2011-1398. Epub 2011 Nov 8.

6.

The role and regulation of 11beta-hydroxysteroid dehydrogenase type 1 in the inflammatory response.

Chapman KE, Coutinho AE, Gray M, Gilmour JS, Savill JS, Seckl JR.

Mol Cell Endocrinol. 2009 Mar 25;301(1-2):123-31. doi: 10.1016/j.mce.2008.09.031. Epub 2008 Oct 8. Review.

PMID:
18973788
7.

Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins.

Lacy-Hulbert A, Smith AM, Tissire H, Barry M, Crowley D, Bronson RT, Roes JT, Savill JS, Hynes RO.

Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15823-8. Epub 2007 Sep 25.

8.
9.

Local amplification of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1 and its role in the inflammatory response.

Chapman KE, Coutinho A, Gray M, Gilmour JS, Savill JS, Seckl JR.

Ann N Y Acad Sci. 2006 Nov;1088:265-73. Review.

PMID:
17192572
10.

Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis.

Rossi AG, Sawatzky DA, Walker A, Ward C, Sheldrake TA, Riley NA, Caldicott A, Martinez-Losa M, Walker TR, Duffin R, Gray M, Crescenzi E, Martin MC, Brady HJ, Savill JS, Dransfield I, Haslett C.

Nat Med. 2006 Sep;12(9):1056-64. Epub 2006 Sep 3. Erratum in: Nat Med. 2006 Dec;12(12):1434. Dosage error in article text.

PMID:
16951685
11.

Local amplification of glucocorticoids by 11 beta-hydroxysteroid dehydrogenase type 1 promotes macrophage phagocytosis of apoptotic leukocytes.

Gilmour JS, Coutinho AE, Cailhier JF, Man TY, Clay M, Thomas G, Harris HJ, Mullins JJ, Seckl JR, Savill JS, Chapman KE.

J Immunol. 2006 Jun 15;176(12):7605-11.

12.

11Beta-hydroxysteroid dehydrogenase type 1--a role in inflammation?

Chapman KE, Gilmour JS, Coutinho AE, Savill JS, Seckl JR.

Mol Cell Endocrinol. 2006 Mar 27;248(1-2):3-8. Epub 2006 Jan 10. Review.

PMID:
16406279
13.

Apoptosis in glomerulonephritis.

Hughes J, Savill JS.

Curr Opin Nephrol Hypertens. 2005 Jul;14(4):389-95. Review.

PMID:
15931010
14.

Apoptosis in glomerulonephritis.

Hughes J, Cailhier JF, Watson S, Savill JS.

Rheum Dis Clin North Am. 2004 Aug;30(3):655-76, xi-xii. Review.

PMID:
15261347
15.

A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo.

Taylor PR, Carugati A, Fadok VA, Cook HT, Andrews M, Carroll MC, Savill JS, Henson PM, Botto M, Walport MJ.

J Exp Med. 2000 Aug 7;192(3):359-66.

16.

Activated macrophages direct apoptosis and suppress mitosis of mesangial cells.

Duffield JS, Erwig LP, Wei X, Liew FY, Rees AJ, Savill JS.

J Immunol. 2000 Feb 15;164(4):2110-9.

17.

Selective sensitization to tumor necrosis factor-alpha-induced apoptosis by blockade of NF-kappaB in primary glomerular mesangial cells.

Sugiyama H, Savill JS, Kitamura M, Zhao L, Stylianou E.

J Biol Chem. 1999 Jul 9;274(28):19532-7.

18.

Dissociation of phagocyte recognition of cells undergoing apoptosis from other features of the apoptotic program.

Zhuang J, Ren Y, Snowden RT, Zhu H, Gogvadze V, Savill JS, Cohen GM.

J Biol Chem. 1998 Jun 19;273(25):15628-32.

20.

Granulocyte apoptosis and the control of inflammation.

Haslett C, Savill JS, Whyte MK, Stern M, Dransfield I, Meagher LC.

Philos Trans R Soc Lond B Biol Sci. 1994 Aug 30;345(1313):327-33. Review.

PMID:
7846130
21.

Neutrophil apoptosis is associated with a reduction in CD16 (Fc gamma RIII) expression.

Dransfield I, Buckle AM, Savill JS, McDowall A, Haslett C, Hogg N.

J Immunol. 1994 Aug 1;153(3):1254-63.

PMID:
8027553
22.

Transient elevations of cytosolic free calcium retard subsequent apoptosis in neutrophils in vitro.

Whyte MK, Hardwick SJ, Meagher LC, Savill JS, Haslett C.

J Clin Invest. 1993 Jul;92(1):446-55.

23.

Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells.

Fadok VA, Savill JS, Haslett C, Bratton DL, Doherty DE, Campbell PA, Henson PM.

J Immunol. 1992 Dec 15;149(12):4029-35.

PMID:
1281199
24.

Phagocytosis of apoptotic neutrophils does not induce macrophage release of thromboxane B2.

Meagher LC, Savill JS, Baker A, Fuller RW, Haslett C.

J Leukoc Biol. 1992 Sep;52(3):269-73.

PMID:
1522386
25.

Ganciclovir treatment for cytomegalovirus infection in immunocompromised patients with renal disease.

Ross CN, Beynon HL, Savill JS, Watkins RP, Cohen J, Pusey CD, Rees AJ.

Q J Med. 1991 Nov;81(295):929-36.

PMID:
1667044
26.

Neutrophil apoptosis and clearance from neonatal lungs.

Grigg JM, Savill JS, Sarraf C, Haslett C, Silverman M.

Lancet. 1991 Sep 21;338(8769):720-2.

PMID:
1679867
27.

Apoptosis (programmed cell death) and functional changes in aging neutrophils. Modulation by inflammatory mediators.

Haslett C, Lee A, Savill JS, Meagher L, Whyte MK.

Chest. 1991 Mar;99(3 Suppl):6S. No abstract available.

PMID:
1997278
28.

Oligosaccharide-mediated interactions of the envelope glycoprotein gp120 of HIV-1 that are independent of CD4 recognition.

Larkin M, Childs RA, Matthews TJ, Thiel S, Mizuochi T, Lawson AM, Savill JS, Haslett C, Diaz R, Feizi T.

AIDS. 1989 Dec;3(12):793-8.

PMID:
2561054
29.
30.

The neutrophil.

Haslett C, Savill JS, Meagher L.

Curr Opin Immunol. 1989 Oct;2(1):10-8. Review.

PMID:
2514726
31.

Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages.

Savill JS, Wyllie AH, Henson JE, Walport MJ, Henson PM, Haslett C.

J Clin Invest. 1989 Mar;83(3):865-75.

32.
33.

Fatal Stevens-Johnson syndrome following urography with iopamidol in systemic lupus erythematosus.

Savill JS, Barrie R, Ghosh S, Muhlemann M, Dawson P, Pusey CD.

Postgrad Med J. 1988 May;64(751):392-4.

34.

Chronic renal failure associated with topical application of paraphenylenediamine.

Savill JS, Rees AJ.

Br Med J (Clin Res Ed). 1987 Mar 7;294(6572):646. No abstract available.

35.

Pneumococcal bacteraemia in mother and son.

Fenton PA, Spencer RC, Savill JS, Grover S.

Br Med J (Clin Res Ed). 1983 Aug 20;287(6391):529-30. No abstract available.

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