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Items: 1 to 50 of 187

1.

Cell Type- and Exposure-Specific Modulation of CD63/CD81-Positive and Tissue Factor-Positive Extracellular Vesicle Release in response to Respiratory Toxicants.

Stassen FRM, van Eijck PH, Savelkoul PHM, Wouters EFM, Rohde GGU, Briedé JJ, Reynaert NL, de Kok TM, Benedikter BJ.

Oxid Med Cell Longev. 2019 Aug 14;2019:5204218. doi: 10.1155/2019/5204218. eCollection 2019.

2.

Contact precautions in single-bed or multiple-bed rooms for patients with extended-spectrum β-lactamase-producing Enterobacteriaceae in Dutch hospitals: a cluster-randomised, crossover, non-inferiority study.

Kluytmans-van den Bergh MFQ, Bruijning-Verhagen PCJ, Vandenbroucke-Grauls CMJE, de Brauwer EIGB, Buiting AGM, Diederen BM, van Elzakker EPM, Friedrich AW, Hopman J, Al Naiemi N, Rossen JWA, Ruijs GJHM, Savelkoul PHM, Verhulst C, Vos MC, Voss A, Bonten MJM, Kluytmans JAJW; SoM Study Group.

Lancet Infect Dis. 2019 Oct;19(10):1069-1079. doi: 10.1016/S1473-3099(19)30262-2. Epub 2019 Aug 23.

PMID:
31451419
3.

Corrigendum. The vaginal microbiome as a predictor for outcome of in vitro fertilization with or without intracytoplasmic sperm injection: a prospective study.

Koedooder R, Singer M, Schoenmakers S, Savelkoul PHM, Morré SA, de Jonge JD, Poort L, Cuypers WJSS, Beckers NGM, Broekmans FJM, Cohlen BJ, den Hartog JE, Fleischer K, Lambalk CB, Smeenk JMJS, Budding AE, Laven JSE.

Hum Reprod. 2019 Oct 2;34(10):2091-2092. doi: 10.1093/humrep/dez127. No abstract available.

PMID:
31299066
4.

Moderate positive predictive value of a multiplex real-time PCR on whole blood for pathogen detection in critically ill patients with sepsis.

van de Groep K, Bos MP, Varkila MRJ, Savelkoul PHM, Ong DSY, Derde LPG, Juffermans NP, van der Poll T, Bonten MJM, Cremer OL; MARS consortium.

Eur J Clin Microbiol Infect Dis. 2019 Oct;38(10):1829-1836. doi: 10.1007/s10096-019-03616-w. Epub 2019 Jun 26.

5.

The vaginal microbiome as a predictor for outcome of in vitro fertilization with or without intracytoplasmic sperm injection: a prospective study.

Koedooder R, Singer M, Schoenmakers S, Savelkoul PHM, Morré SA, de Jonge JD, Poort L, Cuypers WJSS, Beckers NGM, Broekmans FJM, Cohlen BJ, den Hartog JE, Fleischer K, Lambalk CB, Smeenk JMJS, Budding AE, Laven JSE.

Hum Reprod. 2019 Jun 4;34(6):1042-1054. doi: 10.1093/humrep/dez065.

PMID:
31119299
6.

Microbiome on the Bone-Anchored Hearing System: A Prospective Study.

Calon TGA, Trobos M, Johansson ML, van Tongeren J, van der Lugt-Degen M, Janssen AML, Savelkoul PHM, Stokroos RJ, Budding AE.

Front Microbiol. 2019 Apr 26;10:799. doi: 10.3389/fmicb.2019.00799. eCollection 2019.

7.

Proteomic analysis reveals procoagulant properties of cigarette smoke-induced extracellular vesicles.

Benedikter BJ, Bouwman FG, Heinzmann ACA, Vajen T, Mariman EC, Wouters EFM, Savelkoul PHM, Koenen RR, Rohde GGU, van Oerle R, Spronk HM, Stassen FRM.

J Extracell Vesicles. 2019 Mar 5;8(1):1585163. doi: 10.1080/20013078.2019.1585163. eCollection 2019.

8.

Faecal Microbiota Dynamics and their Relation to Disease Course in Crohn's Disease.

Galazzo G, Tedjo DI, Wintjens DSJ, Savelkoul PHM, Masclee AAM, Bodelier AGL, Pierik MJ, Jonkers DMAE, Penders J.

J Crohns Colitis. 2019 Sep 27;13(10):1273-1282. doi: 10.1093/ecco-jcc/jjz049.

9.

Improving peak concentrations of a single dose regime of gentamicin in patients with sepsis in the emergency department.

Cobussen M, Stassen PM, Posthouwer D, van Tiel FH, Savelkoul PHM, Havenith T, Haeseker MB.

PLoS One. 2019 Jan 22;14(1):e0210012. doi: 10.1371/journal.pone.0210012. eCollection 2019.

10.

The effect of surgical fecal stream diversion of the healthy colon on the colonic microbiota.

van der Sluis WB, Bouman MB, Mullender MG, Degen MC, Savelkoul PHM, Meijerink WJHJ, de Boer NKH, van Bodegraven AA, Budding AE.

Eur J Gastroenterol Hepatol. 2019 Apr;31(4):451-457. doi: 10.1097/MEG.0000000000001330.

PMID:
30664020
11.

The fecal and mucosal microbiome in acute appendicitis patients: an observational study.

Peeters T, Penders J, Smeekens SP, Galazzo G, Houben B, Netea MG, Savelkoul PH, Gyssens IC.

Future Microbiol. 2019 Jan;14:111-127. doi: 10.2217/fmb-2018-0203. Epub 2019 Jan 21.

PMID:
30663346
12.

The ReceptIVFity cohort study protocol to validate the urogenital microbiome as predictor for IVF or IVF/ICSI outcome.

Koedooder R, Singer M, Schoenmakers S, Savelkoul PHM, Morré SA, de Jonge JD, Poort L, Cuypers WSS, Budding AE, Laven JSE; ReceptIVFity study group.

Reprod Health. 2018 Dec 7;15(1):202. doi: 10.1186/s12978-018-0653-x.

13.

The Skin Microbiota in Patients Hospitalized for Cellulitis and Association With Outcome.

Cranendonk DR, Hugenholtz F, Prins JM, Savelkoul PHM, Budding AE, Wiersinga WJ; DANCE Consortium .

Clin Infect Dis. 2019 Apr 8;68(8):1292-1299. doi: 10.1093/cid/ciy709.

PMID:
30321312
14.

Gut Microbiota and Body Weight in School-Aged Children: The KOALA Birth Cohort Study.

Mbakwa CA, Hermes GDA, Penders J, Savelkoul PHM, Thijs C, Dagnelie PC, Mommers M, Zoetendal EG, Smidt H, Arts ICW.

Obesity (Silver Spring). 2018 Nov;26(11):1767-1776. doi: 10.1002/oby.22320. Epub 2018 Oct 8.

15.

Extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) isolated from bean sprouts in the Netherlands.

Huizinga P, Schrauwen E, García-Cobos S, Willemsen I, Verhulst C, Friedrich AW, Savelkoul PHM, Rossen JW, Kluytmans J.

PLoS One. 2018 Aug 30;13(8):e0203338. doi: 10.1371/journal.pone.0203338. eCollection 2018.

16.

Variability of core microbiota in newly diagnosed treatment-naïve paediatric inflammatory bowel disease patients.

de Meij TGJ, de Groot EFJ, Peeters CFW, de Boer NKH, Kneepkens CMF, Eck A, Benninga MA, Savelkoul PHM, van Bodegraven AA, Budding AE.

PLoS One. 2018 Aug 13;13(8):e0197649. doi: 10.1371/journal.pone.0197649. eCollection 2018.

17.

Social networks in relation to self-reported symptomatic infections in individuals aged 40-75 - the Maastricht study.

Brinkhues S, Schram MT, Hoebe CJPA, Kretzschmar MEE, Koster A, Dagnelie PC, Sep SJS, van Kuijk SMJ, Savelkoul PHM, Dukers-Muijrers NHTM.

BMC Infect Dis. 2018 Jul 4;18(1):300. doi: 10.1186/s12879-018-3197-3.

18.

Social Network Characteristics Are Associated With Type 2 Diabetes Complications: The Maastricht Study.

Brinkhues S, Dukers-Muijrers NHTM, Hoebe CJPA, van der Kallen CJH, Koster A, Henry RMA, Stehouwer CDA, Savelkoul PHM, Schaper NC, Schram MT.

Diabetes Care. 2018 Aug;41(8):1654-1662. doi: 10.2337/dc17-2144. Epub 2018 Jun 15.

PMID:
29907582
19.

Volatile metabolites in breath strongly correlate with gut microbiome in CD patients.

Smolinska A, Tedjo DI, Blanchet L, Bodelier A, Pierik MJ, Masclee AAM, Dallinga J, Savelkoul PHM, Jonkers DMAE, Penders J, van Schooten FJ.

Anal Chim Acta. 2018 Sep 26;1025:1-11. doi: 10.1016/j.aca.2018.03.046. Epub 2018 Mar 30.

20.

Extracellular vesicles released in response to respiratory exposures: implications for chronic disease.

Benedikter BJ, Wouters EFM, Savelkoul PHM, Rohde GGU, Stassen FRM.

J Toxicol Environ Health B Crit Rev. 2018;21(3):142-160. doi: 10.1080/10937404.2018.1466380. Epub 2018 May 1.

PMID:
29714636
21.

Development and first evaluation of a novel multiplex real-time PCR on whole blood samples for rapid pathogen identification in critically ill patients with sepsis.

van de Groep K, Bos MP, Savelkoul PHM, Rubenjan A, Gazenbeek C, Melchers WJG, van der Poll T, Juffermans NP, Ong DSY, Bonten MJM, Cremer OL; MARS consortium.

Eur J Clin Microbiol Infect Dis. 2018 Jul;37(7):1333-1344. doi: 10.1007/s10096-018-3255-1. Epub 2018 Apr 26.

22.

Evaluation of a real-time PCR assay for detection and quantification of bacterial DNA directly in blood of preterm neonates with suspected late-onset sepsis.

van den Brand M, van den Dungen FAM, Bos MP, van Weissenbruch MM, van Furth AM, de Lange A, Rubenjan A, Peters RPH, Savelkoul PHM.

Crit Care. 2018 Apr 22;22(1):105. doi: 10.1186/s13054-018-2010-4.

23.

Safety and immunogenicity of HBAI20 Hepatitis B vaccine in healthy naïve and nonresponding adults.

Koc ÖM, Savelkoul PHM, van Loo IHM, Peeters A, Oude Lashof AML.

J Viral Hepat. 2018 Sep;25(9):1048-1056. doi: 10.1111/jvh.12909. Epub 2018 May 9.

PMID:
29660190
24.

Redox-dependent thiol modifications: implications for the release of extracellular vesicles.

Benedikter BJ, Weseler AR, Wouters EFM, Savelkoul PHM, Rohde GGU, Stassen FRM.

Cell Mol Life Sci. 2018 Jul;75(13):2321-2337. doi: 10.1007/s00018-018-2806-z. Epub 2018 Mar 28. Review.

25.

Socially isolated individuals are more prone to have newly diagnosed and prevalent type 2 diabetes mellitus - the Maastricht study.

Brinkhues S, Dukers-Muijrers NHTM, Hoebe CJPA, van der Kallen CJH, Dagnelie PC, Koster A, Henry RMA, Sep SJS, Schaper NC, Stehouwer CDA, Bosma H, Savelkoul PHM, Schram MT.

BMC Public Health. 2017 Dec 19;17(1):955. doi: 10.1186/s12889-017-4948-6.

26.

Immunomodulatory role for membrane vesicles released by THP-1 macrophages and respiratory pathogens during macrophage infection.

Volgers C, Benedikter BJ, Grauls GE, Savelkoul PHM, Stassen FRM.

BMC Microbiol. 2017 Nov 13;17(1):216. doi: 10.1186/s12866-017-1122-3.

27.

Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.

Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM.

Sci Rep. 2017 Nov 10;7(1):15297. doi: 10.1038/s41598-017-15717-7.

28.

Interpretation of microbiota-based diagnostics by explaining individual classifier decisions.

Eck A, Zintgraf LM, de Groot EFJ, de Meij TGJ, Cohen TS, Savelkoul PHM, Welling M, Budding AE.

BMC Bioinformatics. 2017 Oct 4;18(1):441. doi: 10.1186/s12859-017-1843-1.

29.

Development of prediction models for upper and lower respiratory and gastrointestinal tract infections using social network parameters in middle-aged and older persons -The Maastricht Study.

Brinkhues S, van Kuijk SMJ, Hoebe CJPA, Savelkoul PHM, Kretzschmar MEE, Jansen MWJ, de Vries N, Sep SJS, Dagnelie PC, Schaper NC, Verhey FRJ, Bosma H, Maes J, Schram MT, Dukers-Muijrers NHTM.

Epidemiol Infect. 2018 Apr;146(5):533-543. doi: 10.1017/S0950268817002187. Epub 2017 Sep 26.

30.

Correction for Eck et al., "Robust Microbiota-Based Diagnostics for Inflammatory Bowel Disease".

Eck A, de Groot EFJ, de Meij TGJ, Welling M, Savelkoul PHM, Budding AE.

J Clin Microbiol. 2017 Sep;55(9):2871. doi: 10.1128/JCM.00958-17. No abstract available.

31.

Gram-negative bacterial membrane vesicle release in response to the host-environment: different threats, same trick?

Volgers C, Savelkoul PHM, Stassen FRM.

Crit Rev Microbiol. 2018 May;44(3):258-273. doi: 10.1080/1040841X.2017.1353949. Epub 2017 Jul 25. Review.

PMID:
28741415
32.

Budesonide, fluticasone propionate, and azithromycin do not modulate the membrane vesicle release by THP-1 macrophages and respiratory pathogens during macrophage infection.

Volgers C, Grauls GE, Hellebrand PHM, Savelkoul PHM, Stassen FRM.

Inflammopharmacology. 2017 Dec;25(6):643-651. doi: 10.1007/s10787-017-0359-7. Epub 2017 May 20.

33.

Bead-based flow-cytometry for semi-quantitative analysis of complex membrane vesicle populations released by bacteria and host cells.

Volgers C, Benedikter BJ, Grauls GE, Savelkoul PHM, Stassen FRM.

Microbiol Res. 2017 Jul;200:25-32. doi: 10.1016/j.micres.2017.04.003. Epub 2017 Apr 2.

34.

Effects of N-acetyl-L-cysteine on the membrane vesicle release and growth of respiratory pathogens.

Volgers C, Benedikter BJ, Grauls GE, Hellebrand PHM, Savelkoul PHM, Stassen FRM.

FEMS Microbiol Lett. 2017 May 1;364(9). doi: 10.1093/femsle/fnx087.

PMID:
28444395
35.

Cigarette smoke extract induced exosome release is mediated by depletion of exofacial thiols and can be inhibited by thiol-antioxidants.

Benedikter BJ, Volgers C, van Eijck PH, Wouters EFM, Savelkoul PHM, Reynaert NL, Haenen GRMM, Rohde GGU, Weseler AR, Stassen FRM.

Free Radic Biol Med. 2017 Jul;108:334-344. doi: 10.1016/j.freeradbiomed.2017.03.026. Epub 2017 Mar 28.

PMID:
28359953
36.

Gut Colonization by Methanogenic Archaea Is Associated with Organic Dairy Consumption in Children.

van de Pol JA, van Best N, Mbakwa CA, Thijs C, Savelkoul PH, Arts IC, Hornef MW, Mommers M, Penders J.

Front Microbiol. 2017 Mar 10;8:355. doi: 10.3389/fmicb.2017.00355. eCollection 2017.

37.

Robust Microbiota-Based Diagnostics for Inflammatory Bowel Disease.

Eck A, de Groot EFJ, de Meij TGJ, Welling M, Savelkoul PHM, Budding AE.

J Clin Microbiol. 2017 Jun;55(6):1720-1732. doi: 10.1128/JCM.00162-17. Epub 2017 Mar 22. Erratum in: J Clin Microbiol. 2017 Sep;55(9):2871.

38.

Viral-bacterial interactions in the respiratory tract.

Bellinghausen C, Rohde GGU, Savelkoul PHM, Wouters EFM, Stassen FRM.

J Gen Virol. 2016 Dec;97(12):3089-3102. doi: 10.1099/jgv.0.000627. Epub 2016 Oct 18. Review.

PMID:
27902340
39.

Characterization of Microbiota in Children with Chronic Functional Constipation.

de Meij TG, de Groot EF, Eck A, Budding AE, Kneepkens CM, Benninga MA, van Bodegraven AA, Savelkoul PH.

PLoS One. 2016 Oct 19;11(10):e0164731. doi: 10.1371/journal.pone.0164731. eCollection 2016.

40.

The fecal microbiota as a biomarker for disease activity in Crohn's disease.

Tedjo DI, Smolinska A, Savelkoul PH, Masclee AA, van Schooten FJ, Pierik MJ, Penders J, Jonkers DM.

Sci Rep. 2016 Oct 13;6:35216. doi: 10.1038/srep35216.

41.

Detection of the plasmid-mediated colistin-resistance gene mcr-1 in faecal metagenomes of Dutch travellers.

von Wintersdorff CJ, Wolffs PF, van Niekerk JM, Beuken E, van Alphen LB, Stobberingh EE, Oude Lashof AM, Hoebe CJ, Savelkoul PH, Penders J.

J Antimicrob Chemother. 2016 Dec;71(12):3416-3419. Epub 2016 Aug 23.

PMID:
27559117
42.

A prospective multicenter evaluation of direct molecular detection of blood stream infection from a clinical perspective.

Nieman AE, Savelkoul PHM, Beishuizen A, Henrich B, Lamik B, MacKenzie CR, Kindgen-Milles D, Helmers A, Diaz C, Sakka SG, Schade RP.

BMC Infect Dis. 2016 Jun 30;16:314. doi: 10.1186/s12879-016-1646-4.

43.

Exposure to common respiratory bacteria alters the airway epithelial response to subsequent viral infection.

Bellinghausen C, Gulraiz F, Heinzmann AC, Dentener MA, Savelkoul PH, Wouters EF, Rohde GG, Stassen FR.

Respir Res. 2016 Jun 3;17(1):68. doi: 10.1186/s12931-016-0382-z.

44.

Stenotrophomonas maltophilia ventilator-associated pneumonia. A retrospective matched case-control study.

Scholte JB, Zhou TL, Bergmans DC, Rohde GG, Winkens B, Van Dessel HA, Dormans TP, Linssen CF, Roekaerts PM, Savelkoul PH, van Mook WN.

Infect Dis (Lond). 2016 Oct;48(10):738-43. doi: 10.1080/23744235.2016.1185534. Epub 2016 May 20.

PMID:
27207483
45.

The gut resistome is highly dynamic during the first months of life.

von Wintersdorff CJ, Wolffs PF, Savelkoul PH, Nijsen RR, Lau S, Gerhold K, Hamelmann E, Penders J.

Future Microbiol. 2016;11(4):501-10. doi: 10.2217/fmb.15.154. Epub 2016 Apr 11.

PMID:
27064174
46.

Long-Term Green Tea Supplementation Does Not Change the Human Gut Microbiota.

Janssens PL, Penders J, Hursel R, Budding AE, Savelkoul PH, Westerterp-Plantenga MS.

PLoS One. 2016 Apr 7;11(4):e0153134. doi: 10.1371/journal.pone.0153134. eCollection 2016.

47.

Presence of mcr-1-positive Enterobacteriaceae in retail chicken meat but not in humans in the Netherlands since 2009.

Kluytmans-van den Bergh MF, Huizinga P, Bonten MJ, Bos M, De Bruyne K, Friedrich AW, Rossen JW, Savelkoul PH, Kluytmans JA.

Euro Surveill. 2016;21(9):30149. doi: 10.2807/1560-7917.ES.2016.21.9.30149.

48.

Dissemination of Antimicrobial Resistance in Microbial Ecosystems through Horizontal Gene Transfer.

von Wintersdorff CJ, Penders J, van Niekerk JM, Mills ND, Majumder S, van Alphen LB, Savelkoul PH, Wolffs PF.

Front Microbiol. 2016 Feb 19;7:173. doi: 10.3389/fmicb.2016.00173. eCollection 2016. Review.

49.

Automated Broad-Range Molecular Detection of Bacteria in Clinical Samples.

Budding AE, Hoogewerf M, Vandenbroucke-Grauls CM, Savelkoul PH.

J Clin Microbiol. 2016 Apr;54(4):934-43. doi: 10.1128/JCM.02886-15. Epub 2016 Jan 13.

50.

Prevalence and risk factors for carriage of ESBL-producing Enterobacteriaceae in Amsterdam.

Reuland EA, Al Naiemi N, Kaiser AM, Heck M, Kluytmans JA, Savelkoul PH, Elders PJ, Vandenbroucke-Grauls CM.

J Antimicrob Chemother. 2016 Apr;71(4):1076-82. doi: 10.1093/jac/dkv441. Epub 2016 Jan 10.

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