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Items: 26

1.

Temporal evolution of the microbiome, immune system, and epigenome with disease progression in ALS mice.

Figueroa-Romero C, Guo K, Murdock BJ, Paez-Colasante X, Bassis CM, Mikhail KA, Raue KD, Evans MC, Taubman GF, McDermott AJ, O'Brien PD, Savelieff MG, Hur J, Feldman EL.

Dis Model Mech. 2019 Oct 9. pii: dmm.041947. doi: 10.1242/dmm.041947. [Epub ahead of print]

2.

Disorders of mitochondrial dynamics in peripheral neuropathy: Clues from hereditary neuropathy and diabetes.

Rumora AE, Savelieff MG, Sakowski SA, Feldman EL.

Int Rev Neurobiol. 2019;145:127-176. doi: 10.1016/bs.irn.2019.05.002. Epub 2019 Jun 6.

PMID:
31208522
3.

Stem cell treatments for amyotrophic lateral sclerosis: a critical overview of early phase trials.

Goutman SA, Savelieff MG, Sakowski SA, Feldman EL.

Expert Opin Investig Drugs. 2019 Jun;28(6):525-543. doi: 10.1080/13543784.2019.1627324. Epub 2019 Jun 12. Review. Erratum in: Expert Opin Ther Pat. 2019 Jul 4;:1-7.

PMID:
31189354
4.

IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response.

Núñez FJ, Mendez FM, Kadiyala P, Alghamri MS, Savelieff MG, Garcia-Fabiani MB, Haase S, Koschmann C, Calinescu AA, Kamran N, Saxena M, Patel R, Carney S, Guo MZ, Edwards M, Ljungman M, Qin T, Sartor MA, Tagett R, Venneti S, Brosnan-Cashman J, Meeker A, Gorbunova V, Zhao L, Kremer DM, Zhang L, Lyssiotis CA, Jones L, Herting CJ, Ross JL, Hambardzumyan D, Hervey-Jumper S, Figueroa ME, Lowenstein PR, Castro MG.

Sci Transl Med. 2019 Feb 13;11(479). pii: eaaq1427. doi: 10.1126/scitranslmed.aaq1427.

5.

The current status of avian aspergillosis diagnoses: Veterinary practice to novel research avenues.

Savelieff MG, Pappalardo L, Azmanis P.

Vet Clin Pathol. 2018 Sep;47(3):342-362. doi: 10.1111/vcp.12644. Epub 2018 Aug 17. Review.

PMID:
30117564
6.

CSF H3F3A K27M circulating tumor DNA copy number quantifies tumor growth and in vitro treatment response.

Stallard S, Savelieff MG, Wierzbicki K, Mullan B, Miklja Z, Bruzek A, Garcia T, Siada R, Anderson B, Singer BH, Hashizume R, Carcaboso AM, McMurray KQ, Heth J, Muraszko K, Robertson PL, Mody R, Venneti S, Garton H, Koschmann C.

Acta Neuropathol Commun. 2018 Aug 15;6(1):80. doi: 10.1186/s40478-018-0580-7. No abstract available.

7.

Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis in the Last Decade.

Savelieff MG, Nam G, Kang J, Lee HJ, Lee M, Lim MH.

Chem Rev. 2019 Jan 23;119(2):1221-1322. doi: 10.1021/acs.chemrev.8b00138. Epub 2018 Aug 10.

PMID:
30095897
8.

Calprotectin influences the aggregation of metal-free and metal-bound amyloid-β by direct interaction.

Lee HJ, Savelieff MG, Kang J, Brophy MB, Nakashige TG, Lee SJC, Nolan EM, Lim MH.

Metallomics. 2018 Aug 15;10(8):1116-1127. doi: 10.1039/c8mt00091c.

PMID:
30046785
9.

Novel cutting-edge metabolite-based diagnostic tools for aspergillosis.

Savelieff MG, Pappalardo L.

PLoS Pathog. 2017 Sep 7;13(9):e1006486. doi: 10.1371/journal.ppat.1006486. eCollection 2017 Sep. Review. No abstract available.

10.

Correction to Thiolate Spin Population of Type I Copper in Azurin Derived from 33S Hyperfine Coupling.

Cohen MR, Mendelman N, Radoul M, Wilson TD, Savelieff MG, Zimmermann H, Kaminker I, Feintuch A, Lu Y, Goldfarb D.

Inorg Chem. 2017 Aug 21;56(16):10117. doi: 10.1021/acs.inorgchem.7b01753. Epub 2017 Aug 4. No abstract available.

PMID:
28776989
11.

Thiolate Spin Population of Type I Copper in Azurin Derived from 33S Hyperfine Coupling.

Ramirez Cohen M, Mendelman N, Radoul M, Wilson TD, Savelieff MG, Zimmermann H, Kaminker I, Feintuch A, Lu Y, Goldfarb D.

Inorg Chem. 2017 Jun 5;56(11):6163-6174. doi: 10.1021/acs.inorgchem.7b00167. Epub 2017 May 16. Erratum in: Inorg Chem. 2017 Aug 21;56(16):10117.

PMID:
28509562
12.

Towards an understanding of amyloid-β oligomers: characterization, toxicity mechanisms, and inhibitors.

Lee SJ, Nam E, Lee HJ, Savelieff MG, Lim MH.

Chem Soc Rev. 2017 Jan 23;46(2):310-323. doi: 10.1039/c6cs00731g. Review.

PMID:
27878186
13.

The ongoing search for small molecules to study metal-associated amyloid-β species in Alzheimer's disease.

Savelieff MG, DeToma AS, Derrick JS, Lim MH.

Acc Chem Res. 2014 Aug 19;47(8):2475-82. doi: 10.1021/ar500152x. Epub 2014 Jul 31.

PMID:
25080056
14.

GM130 is required for compartmental organization of dendritic golgi outposts.

Zhou W, Chang J, Wang X, Savelieff MG, Zhao Y, Ke S, Ye B.

Curr Biol. 2014 Jun 2;24(11):1227-33. doi: 10.1016/j.cub.2014.04.008. Epub 2014 May 15.

15.

Correlating nuclear frequencies by two-dimensional ELDOR-detected NMR spectroscopy.

Kaminker I, Wilson TD, Savelieff MG, Hovav Y, Zimmermann H, Lu Y, Goldfarb D.

J Magn Reson. 2014 Mar;240:77-89. doi: 10.1016/j.jmr.2013.12.016. Epub 2014 Jan 27.

PMID:
24530956
16.

Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease.

Lee S, Zheng X, Krishnamoorthy J, Savelieff MG, Park HM, Brender JR, Kim JH, Derrick JS, Kochi A, Lee HJ, Kim C, Ramamoorthy A, Bowers MT, Lim MH.

J Am Chem Soc. 2014 Jan 8;136(1):299-310. doi: 10.1021/ja409801p. Epub 2013 Dec 27.

17.

A small molecule that displays marked reactivity toward copper- versus zinc-amyloid-β implicated in Alzheimer's disease.

Savelieff MG, Liu Y, Senthamarai RR, Korshavn KJ, Lee HJ, Ramamoorthy A, Lim MH.

Chem Commun (Camb). 2014 May 25;50(40):5301-3. doi: 10.1039/c3cc48473d. Epub 2013 Dec 10.

18.

Untangling amyloid-β, tau, and metals in Alzheimer's disease.

Savelieff MG, Lee S, Liu Y, Lim MH.

ACS Chem Biol. 2013 May 17;8(5):856-65. doi: 10.1021/cb400080f. Epub 2013 Mar 18. Review.

PMID:
23506614
19.

Kinetics of copper incorporation into a biosynthetic purple Cu(A) azurin: characterization of red, blue, and a new intermediate species.

Wilson TD, Savelieff MG, Nilges MJ, Marshall NM, Lu Y.

J Am Chem Soc. 2011 Dec 28;133(51):20778-92. doi: 10.1021/ja205281t. Epub 2011 Dec 2.

PMID:
21985501
20.

Cu(A) centers and their biosynthetic models in azurin.

Savelieff MG, Lu Y.

J Biol Inorg Chem. 2010 May;15(4):461-83. doi: 10.1007/s00775-010-0625-2. Epub 2010 Feb 19. Review.

PMID:
20169379
21.

Experimental evidence for a link among cupredoxins: red, blue, and purple copper transformations in nitrous oxide reductase.

Savelieff MG, Wilson TD, Elias Y, Nilges MJ, Garner DK, Lu Y.

Proc Natl Acad Sci U S A. 2008 Jun 10;105(23):7919-24. doi: 10.1073/pnas.0711316105. Epub 2008 Jun 5.

22.

Reduction potential tuning of the blue copper center in Pseudomonas aeruginosa azurin by the axial methionine as probed by unnatural amino acids.

Garner DK, Vaughan MD, Hwang HJ, Savelieff MG, Berry SM, Honek JF, Lu Y.

J Am Chem Soc. 2006 Dec 13;128(49):15608-17.

PMID:
17147368
23.

Heteropolymolybdates of AsIII, SbIII, BiIII, SeIV, and TeIV functionalized by amino acids.

Kortz U, Savelieff MG, Ghali FY, Khalil LM, Maalouf SA, Sinno DI.

Angew Chem Int Ed Engl. 2002 Nov 4;41(21):4070-3. No abstract available.

PMID:
12412084

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