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Items: 1 to 50 of 646

1.

Rational engineering of 2-deoxyribose-5-phosphate aldolases for the biosynthesis of (R)-1,3-butanediol.

Kim T, Stogios PJ, Khusnutdinova AN, Nemr K, Skarina T, Flick R, Joo JC, Mahadevan R, Savchenko A, Yakunin AF.

J Biol Chem. 2019 Dec 5. pii: jbc.RA119.011363. doi: 10.1074/jbc.RA119.011363. [Epub ahead of print]

2.

A community-based lung cancer rapid tissue donation protocol provides high-quality drug-resistant specimens for proteogenomic analyses.

Boyle TA, Quinn GP, Schabath MB, Muñoz-Antonia T, Saller JJ, Duarte LF, Hair LS, Teer JK, Chiang DY, Leary R, Wong CC, Savchenko A, Singh AP, Charette L, Mendell K, Gorgun G, Antonia SJ, Chiappori AA, Creelan BC, Gray JE, Haura EB.

Cancer Med. 2019 Nov 20. doi: 10.1002/cam4.2670. [Epub ahead of print]

3.

An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp.

Ahmad S, Wang B, Walker MD, Tran HR, Stogios PJ, Savchenko A, Grant RA, McArthur AG, Laub MT, Whitney JC.

Nature. 2019 Nov;575(7784):674-678. doi: 10.1038/s41586-019-1735-9. Epub 2019 Nov 6.

PMID:
31695193
4.

Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon.

Tan YP, Xue Y, Savchenko AI, Houston SD, Modhiran N, McMillan CLD, Boyle GM, Bernhardt PV, Young PR, Watterson D, Williams CM.

J Nat Prod. 2019 Oct 25;82(10):2828-2834. doi: 10.1021/acs.jnatprod.9b00522. Epub 2019 Sep 25.

PMID:
31553187
5.

The Spatial Metabolic Heterogeneity of Solid Type of Enrlich Carcinoma.

Inzhevatkin EV, Savchenko AA.

Dokl Biochem Biophys. 2019 May;486(1):234-237. doi: 10.1134/S1607672919030177. Epub 2019 Jul 31.

PMID:
31367829
6.

Substrate specificity, regiospecificity, and processivity in glycoside hydrolase family 74.

Arnal G, Stogios PJ, Asohan J, Attia MA, Skarina T, Viborg AH, Henrissat B, Savchenko A, Brumer H.

J Biol Chem. 2019 Sep 6;294(36):13233-13247. doi: 10.1074/jbc.RA119.009861. Epub 2019 Jul 19.

7.

[Method of preventing late hemorrhagic complications after surgical treatment of secondary neovascular glaucoma].

Ivanova NV, Savchenko AV.

Vestn Oftalmol. 2019;135(2):12-15. doi: 10.17116/oftalma201913502112. Russian.

PMID:
31215529
8.

Complete Genome Sequence of Citrobacter rodentium Strain DBS100.

Popov G, Fiebig-Comyn A, Shideler S, Coombes BK, Savchenko A.

Microbiol Resour Announc. 2019 Jun 13;8(24). pii: e00421-19. doi: 10.1128/MRA.00421-19.

9.

Semaphorin-5A downregulation is associated with enhanced migration and invasion of BRAF-positive melanoma cells under vemurafenib treatment in melanomas with heterogeneous BRAF status.

Komina AV, Palkina NV, Aksenenko MB, Lavrentev SN, Moshev AV, Savchenko AA, Averchuk AS, Rybnikov YA, Ruksha TG.

Melanoma Res. 2019 Oct;29(5):544-548. doi: 10.1097/CMR.0000000000000621.

PMID:
31116162
10.

Probabilistic Neural Network With Complex Exponential Activation Functions in Image Recognition.

Savchenko AV.

IEEE Trans Neural Netw Learn Syst. 2019 Apr 26. doi: 10.1109/TNNLS.2019.2908973. [Epub ahead of print]

PMID:
31034422
11.

Stachyonic Acid: A Dengue Virus Inhibitor from Basilicum polystachyon.

Tan YP, Houston SD, Modhiran N, Savchenko AI, Boyle GM, Young PR, Watterson D, Williams CM.

Chemistry. 2019 Apr 17;25(22):5664-5667. doi: 10.1002/chem.201900591. Epub 2019 Mar 29.

PMID:
30924209
12.

Megaphylogeny resolves global patterns of mushroom evolution.

Varga T, Krizsán K, Földi C, Dima B, Sánchez-García M, Sánchez-Ramírez S, Szöllősi GJ, Szarkándi JG, Papp V, Albert L, Andreopoulos W, Angelini C, Antonín V, Barry KW, Bougher NL, Buchanan P, Buyck B, Bense V, Catcheside P, Chovatia M, Cooper J, Dämon W, Desjardin D, Finy P, Geml J, Haridas S, Hughes K, Justo A, Karasiński D, Kautmanova I, Kiss B, Kocsubé S, Kotiranta H, LaButti KM, Lechner BE, Liimatainen K, Lipzen A, Lukács Z, Mihaltcheva S, Morgado LN, Niskanen T, Noordeloos ME, Ohm RA, Ortiz-Santana B, Ovrebo C, Rácz N, Riley R, Savchenko A, Shiryaev A, Soop K, Spirin V, Szebenyi C, Tomšovský M, Tulloss RE, Uehling J, Grigoriev IV, Vágvölgyi C, Papp T, Martin FM, Miettinen O, Hibbett DS, Nagy LG.

Nat Ecol Evol. 2019 Apr;3(4):668-678. doi: 10.1038/s41559-019-0834-1. Epub 2019 Mar 18.

13.

Setd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice.

Moore SM, Seidman JS, Ellegood J, Gao R, Savchenko A, Troutman TD, Abe Y, Stender J, Lee D, Wang S, Voytek B, Lerch JP, Suh H, Glass CK, Muotri AR.

Transl Psychiatry. 2019 Jan 17;9(1):24. doi: 10.1038/s41398-018-0344-y.

14.

New Casbanes and the First trans-Cyclopropane seco-Casbane from the Australian Rainforest Plant Croton insularis.

Maslovskaya LA, Savchenko AI, Pierce CJ, Boyle GM, Gordon VA, Reddell PW, Parsons PG, Williams CM.

Chemistry. 2019 Jan 28;25(6):1525-1534. doi: 10.1002/chem.201804904. Epub 2019 Jan 2.

PMID:
30601580
15.

Structural enzymology reveals the molecular basis of substrate regiospecificity and processivity of an exemplar bacterial glycoside hydrolase family 74 endo-xyloglucanase.

Arnal G, Stogios PJ, Asohan J, Skarina T, Savchenko A, Brumer H.

Biochem J. 2018 Dec 19;475(24):3963-3978. doi: 10.1042/BCJ20180763.

PMID:
30463871
16.

Size-selected Fe3O4-Au hybrid nanoparticles for improved magnetism-based theranostics.

Efremova MV, Nalench YA, Myrovali E, Garanina AS, Grebennikov IS, Gifer PK, Abakumov MA, Spasova M, Angelakeris M, Savchenko AG, Farle M, Klyachko NL, Majouga AG, Wiedwald U.

Beilstein J Nanotechnol. 2018 Oct 16;9:2684-2699. doi: 10.3762/bjnano.9.251. eCollection 2018.

17.

Identification and characterization of a large family of superbinding bacterial SH2 domains.

Kaneko T, Stogios PJ, Ruan X, Voss C, Evdokimova E, Skarina T, Chung A, Liu X, Li L, Savchenko A, Ensminger AW, Li SS.

Nat Commun. 2018 Oct 31;9(1):4549. doi: 10.1038/s41467-018-06943-2.

18.

Screening and Characterization of Novel Polyesterases from Environmental Metagenomes with High Hydrolytic Activity against Synthetic Polyesters.

Hajighasemi M, Tchigvintsev A, Nocek B, Flick R, Popovic A, Hai T, Khusnutdinova AN, Brown G, Xu X, Cui H, Anstett J, Chernikova TN, Brüls T, Le Paslier D, Yakimov MM, Joachimiak A, Golyshina OV, Savchenko A, Golyshin PN, Edwards EA, Yakunin AF.

Environ Sci Technol. 2018 Nov 6;52(21):12388-12401. doi: 10.1021/acs.est.8b04252. Epub 2018 Oct 15.

PMID:
30284819
19.

Functional diversification of the NleG effector family in enterohemorrhagic Escherichia coli.

Valleau D, Little DJ, Borek D, Skarina T, Quaile AT, Di Leo R, Houliston S, Lemak A, Arrowsmith CH, Coombes BK, Savchenko A.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10004-10009. doi: 10.1073/pnas.1718350115. Epub 2018 Sep 14.

20.

[CERVICAL CANCER REHABILITATION: A PROSPECTIVE STUDY].

Idrisova L, Solopova A, Savchenko A, Makacarya A, Chukanova E, Alipov V, Kapanadze D.

Georgian Med News. 2018 Jul-Aug;(280-281):17-23. Russian.

PMID:
30204088
21.

Galectin-9 binds IgM-BCR to regulate B cell signaling.

Cao A, Alluqmani N, Buhari FHM, Wasim L, Smith LK, Quaile AT, Shannon M, Hakim Z, Furmli H, Owen DM, Savchenko A, Treanor B.

Nat Commun. 2018 Aug 17;9(1):3288. doi: 10.1038/s41467-018-05771-8.

22.

[Possible Genetic Predictors of Cardiovascular Complications After Coronary Artery Bypass Surgery].

Grinshtein YI, Kosinova AA, Grinshtein IY, Subbotina TN, Savchenko AA.

Kardiologiia. 2018 Jul;58(7):77-84. Russian.

PMID:
30081812
23.

Magnetite-Gold nanohybrids as ideal all-in-one platforms for theranostics.

Efremova MV, Naumenko VA, Spasova M, Garanina AS, Abakumov MA, Blokhina AD, Melnikov PA, Prelovskaya AO, Heidelmann M, Li ZA, Ma Z, Shchetinin IV, Golovin YI, Kireev II, Savchenko AG, Chekhonin VP, Klyachko NL, Farle M, Majouga AG, Wiedwald U.

Sci Rep. 2018 Jul 26;8(1):11295. doi: 10.1038/s41598-018-29618-w.

24.

miR-204-5p and miR-3065-5p exert antitumor effects on melanoma cells.

Palkina N, Komina A, Aksenenko M, Moshev A, Savchenko A, Ruksha T.

Oncol Lett. 2018 Jun;15(6):8269-8280. doi: 10.3892/ol.2018.8443. Epub 2018 Apr 5.

25.

Graphene biointerfaces for optical stimulation of cells.

Savchenko A, Cherkas V, Liu C, Braun GB, Kleschevnikov A, Miller YI, Molokanova E.

Sci Adv. 2018 May 18;4(5):eaat0351. doi: 10.1126/sciadv.aat0351. eCollection 2018 May.

26.

Discovery of Ubiquitin Deamidases in the Pathogenic Arsenal of Legionella pneumophila.

Valleau D, Quaile AT, Cui H, Xu X, Evdokimova E, Chang C, Cuff ME, Urbanus ML, Houliston S, Arrowsmith CH, Ensminger AW, Savchenko A.

Cell Rep. 2018 Apr 10;23(2):568-583. doi: 10.1016/j.celrep.2018.03.060.

27.

Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes.

Cox G, Ejim L, Stogios PJ, Koteva K, Bordeleau E, Evdokimova E, Sieron AO, Savchenko A, Serio AW, Krause KM, Wright GD.

ACS Infect Dis. 2018 Jun 8;4(6):980-987. doi: 10.1021/acsinfecdis.8b00001. Epub 2018 Apr 19.

28.

Substrate Recognition by a Colistin Resistance Enzyme from Moraxella catarrhalis.

Stogios PJ, Cox G, Zubyk HL, Evdokimova E, Wawrzak Z, Wright GD, Savchenko A.

ACS Chem Biol. 2018 May 18;13(5):1322-1332. doi: 10.1021/acschembio.8b00116. Epub 2018 Apr 19.

29.

Synthesis of Iron Oxide Nanoclusters by Thermal Decomposition.

Nikitin AA, Shchetinin IV, Tabachkova NY, Soldatov MA, Soldatov AV, Sviridenkova NV, Beloglazkina EK, Savchenko AG, Fedorova ND, Abakumov MA, Majouga AG.

Langmuir. 2018 Apr 17;34(15):4640-4650. doi: 10.1021/acs.langmuir.8b00753. Epub 2018 Apr 6.

PMID:
29566327
30.

The Development of New Factor Xa Inhibitors Based on Amide Synthesis.

Tarasov DN, Tovbin DG, Malakhov DV, Aybush AV, Tserkovnikova NA, Savelyeva MI, Sychev DA, Drozd NN, Savchenko AY.

Curr Drug Discov Technol. 2018;15(4):335-350. doi: 10.2174/1570163815666180215114732.

31.

The Prognostic Value of Combinations of Genetic Polymorphisms in the ITGB3, ITGA2, and CYP2C19*2 Genes in Predicting Cardiovascular Outcomes After Coronary Bypass Grafting.

Grinshtein YI, Kosinova AA, Grinshtein IY, Subbotina TN, Savchenko AA.

Genet Test Mol Biomarkers. 2018 Apr;22(4):259-265. doi: 10.1089/gtmb.2017.0177. Epub 2018 Feb 20.

PMID:
29461866
32.

Rox, a Rifamycin Resistance Enzyme with an Unprecedented Mechanism of Action.

Koteva K, Cox G, Kelso JK, Surette MD, Zubyk HL, Ejim L, Stogios P, Savchenko A, Sørensen D, Wright GD.

Cell Chem Biol. 2018 Apr 19;25(4):403-412.e5. doi: 10.1016/j.chembiol.2018.01.009. Epub 2018 Feb 1.

33.

Aphyllophoroid fungi in insular woodlands of eastern Ukraine.

Ordynets A, Savchenko A, Akulov A, Yurchenko E, Malysheva VF, Kõljalg U, Vlasák J, Larsson KH, Langer E.

Biodivers Data J. 2017 Dec 22;(5):e22426. doi: 10.3897/BDJ.5.e22426. eCollection 2017.

34.

The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.

Pawlowski AC, Stogios PJ, Koteva K, Skarina T, Evdokimova E, Savchenko A, Wright GD.

Nat Commun. 2018 Jan 9;9(1):112. doi: 10.1038/s41467-017-02680-0.

35.

The Legionella pneumophila effector Ceg4 is a phosphotyrosine phosphatase that attenuates activation of eukaryotic MAPK pathways.

Quaile AT, Stogios PJ, Egorova O, Evdokimova E, Valleau D, Nocek B, Kompella PS, Peisajovich S, Yakunin AF, Ensminger AW, Savchenko A.

J Biol Chem. 2018 Mar 2;293(9):3307-3320. doi: 10.1074/jbc.M117.812727. Epub 2018 Jan 4.

36.

[Neutrophil respiratory burst and the state of hemostasis in patients with ischemic and hemorrhagic stroke].

Savchenko AA, Pavlova OM, Khalo NV, Gvozdev II.

Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(12. Vyp. 2):75-80. doi: 10.17116/jnevro201811812275. Russian.

PMID:
30830121
37.

Determinants and Prediction of Esterase Substrate Promiscuity Patterns.

Martínez-Martínez M, Coscolín C, Santiago G, Chow J, Stogios PJ, Bargiela R, Gertler C, Navarro-Fernández J, Bollinger A, Thies S, Méndez-García C, Popovic A, Brown G, Chernikova TN, García-Moyano A, Bjerga GEK, Pérez-García P, Hai T, Del Pozo MV, Stokke R, Steen IH, Cui H, Xu X, Nocek BP, Alcaide M, Distaso M, Mesa V, Peláez AI, Sánchez J, Buchholz PCF, Pleiss J, Fernández-Guerra A, Glöckner FO, Golyshina OV, Yakimov MM, Savchenko A, Jaeger KE, Yakunin AF, Streit WR, Golyshin PN, Guallar V, Ferrer M, The Inmare Consortium.

ACS Chem Biol. 2018 Jan 19;13(1):225-234. doi: 10.1021/acschembio.7b00996. Epub 2017 Dec 20.

PMID:
29182315
38.

An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes.

McKeithan WL, Savchenko A, Yu MS, Cerignoli F, Bruyneel AAN, Price JH, Colas AR, Miller EW, Cashman JR, Mercola M.

Front Physiol. 2017 Oct 11;8:766. doi: 10.3389/fphys.2017.00766. eCollection 2017.

39.

The metabolic changes in tumor-associated macrophages during cancer grow in mice with Ehrlich ascites carcinoma.

Inzhevatkin EV, Savchenko AA.

Dokl Biochem Biophys. 2017 Jul;475(1):277-279. doi: 10.1134/S1607672917040081. Epub 2017 Sep 2.

PMID:
28864893
40.

An improved preparation of phorbol from croton oil.

Pagani A, Gaeta S, Savchenko AI, Williams CM, Appendino G.

Beilstein J Org Chem. 2017 Jul 11;13:1361-1367. doi: 10.3762/bjoc.13.133. eCollection 2017.

41.

Structural and Functional Survey of Environmental Aminoglycoside Acetyltransferases Reveals Functionality of Resistance Enzymes.

Xu Z, Stogios PJ, Quaile AT, Forsberg KJ, Patel S, Skarina T, Houliston S, Arrowsmith C, Dantas G, Savchenko A.

ACS Infect Dis. 2017 Sep 8;3(9):653-665. doi: 10.1021/acsinfecdis.7b00068. Epub 2017 Aug 16.

PMID:
28756664
42.

Furofuran lignans from the Simpson Desert species Eremophila macdonnellii.

Tan YP, Savchenko AI, Broit N, Boyle GM, Parsons PG, Williams CM.

Fitoterapia. 2018 Apr;126:93-97. doi: 10.1016/j.fitote.2017.06.004. Epub 2017 Jul 15.

PMID:
28596028
43.

[Connexin 43 expression in human brain glial tumors].

Kirichenko EY, Savchenko AF, Kozachenko DV, Akimenko MA, Filippova SY, Matsionis AE, Povilaitite PE.

Arkh Patol. 2017;79(2):3-9. doi: 10.17116/patol20177923-9. Russian.

PMID:
28418351
44.

[Ultrastructural characteristics of gap junctions in human glial brain tumors].

Kirichenko EY, Savchenko AF, Kozachenko DV, Matsionis AE, Logvinov AK.

Arkh Patol. 2017;79(1):3-11. doi: 10.17116/patol20177913-11. Russian.

PMID:
28295002
45.

[Platelet Metabolism in Clopidogrel Resistant and Sensitive Patients With Ischemic Heart Disease].

Grinshtein IY, Savchenko AA, Grinshtein YI, Filonenko IV, Kosinova AA.

Kardiologiia. 2016 Oct;56(10):5-12. Russian.

PMID:
28290889
46.

Activity screening of environmental metagenomic libraries reveals novel carboxylesterase families.

Popovic A, Hai T, Tchigvintsev A, Hajighasemi M, Nocek B, Khusnutdinova AN, Brown G, Glinos J, Flick R, Skarina T, Chernikova TN, Yim V, Brüls T, Paslier DL, Yakimov MM, Joachimiak A, Ferrer M, Golyshina OV, Savchenko A, Golyshin PN, Yakunin AF.

Sci Rep. 2017 Mar 8;7:44103. doi: 10.1038/srep44103.

47.

Bringing new dimensions to drug discovery screening: impact of cellular stimulation technologies.

Molokanova E, Mercola M, Savchenko A.

Drug Discov Today. 2017 Jul;22(7):1045-1055. doi: 10.1016/j.drudis.2017.01.015. Epub 2017 Feb 4. Review.

48.

Novel Aldo-Keto Reductases for the Biocatalytic Conversion of 3-Hydroxybutanal to 1,3-Butanediol: Structural and Biochemical Studies.

Kim T, Flick R, Brunzelle J, Singer A, Evdokimova E, Brown G, Joo JC, Minasov GA, Anderson WF, Mahadevan R, Savchenko A, Yakunin AF.

Appl Environ Microbiol. 2017 Mar 17;83(7). pii: e03172-16. doi: 10.1128/AEM.03172-16. Print 2017 Apr 1.

49.

[The alterations of indices of collagen-induced aggregation of thrombocytes in qualified sportsmen in the dynamics of annual macro-cycle.]

Bazarin KP, Savchenko AA.

Klin Lab Diagn. 2017;62(11):686-689. doi: 10.18821/0869-2084-2017-62-11-686-689. Russian.

PMID:
30840374
50.

Peptidylarginine deiminase 4 promotes age-related organ fibrosis.

Martinod K, Witsch T, Erpenbeck L, Savchenko A, Hayashi H, Cherpokova D, Gallant M, Mauler M, Cifuni SM, Wagner DD.

J Exp Med. 2017 Feb;214(2):439-458. doi: 10.1084/jem.20160530. Epub 2016 Dec 28.

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