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Items: 28


Regulatory T Cell Development.

Savage PA, Klawon DEJ, Miller CH.

Annu Rev Immunol. 2020 Jan 28. doi: 10.1146/annurev-immunol-100219-020937. [Epub ahead of print]


Immune profiles in primary squamous cell carcinoma of the head and neck.

Saloura V, Izumchenko E, Zuo Z, Bao R, Korzinkin M, Ozerov I, Zhavoronkov A, Sidransky D, Bedi A, Hoque MO, Koeppen H, Keck MK, Khattri A, London N, Kotlov N, Fatima A, Vougiouklakis T, Nakamura Y, Lingen M, Agrawal N, Savage PA, Kron S, Kline J, Kowanetz M, Seiwert TY.

Oral Oncol. 2019 Sep;96:77-88. doi: 10.1016/j.oraloncology.2019.06.032. Epub 2019 Jul 12.


Negligible Role for Deletion Mediated by cDC1 in CD8+ T Cell Tolerance.

MacNabb BW, Kline DE, Albright AR, Chen X, Leventhal DS, Savage PA, Kline J.

J Immunol. 2019 May 1;202(9):2628-2635. doi: 10.4049/jimmunol.1801621. Epub 2019 Mar 22.


Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability.

Nalle SC, Zuo L, Ong MLDM, Singh G, Worthylake AM, Choi W, Manresa MC, Southworth AP, Edelblum KL, Baker GJ, Joseph NE, Savage PA, Turner JR.

J Clin Invest. 2019 Feb 1;129(2):902-914. doi: 10.1172/JCI98554. Epub 2019 Jan 22.


Unlocking the Complexities of Tumor-Associated Regulatory T Cells.

Chao JL, Savage PA.

J Immunol. 2018 Jan 15;200(2):415-421. doi: 10.4049/jimmunol.1701188. Review.


Identification of Natural Regulatory T Cell Epitopes Reveals Convergence on a Dominant Autoantigen.

Leonard JD, Gilmore DC, Dileepan T, Nawrocka WI, Chao JL, Schoenbach MH, Jenkins MK, Adams EJ, Savage PA.

Immunity. 2017 Jul 18;47(1):107-117.e8. doi: 10.1016/j.immuni.2017.06.015. Epub 2017 Jul 11.


Aire Enforces Immune Tolerance by Directing Autoreactive T Cells into the Regulatory T Cell Lineage.

Malchow S, Leventhal DS, Lee V, Nishi S, Socci ND, Savage PA.

Immunity. 2016 May 17;44(5):1102-13. doi: 10.1016/j.immuni.2016.02.009. Epub 2016 Apr 26.


Dendritic Cells Coordinate the Development and Homeostasis of Organ-Specific Regulatory T Cells.

Leventhal DS, Gilmore DC, Berger JM, Nishi S, Lee V, Malchow S, Kline DE, Kline J, Vander Griend DJ, Huang H, Socci ND, Savage PA.

Immunity. 2016 Apr 19;44(4):847-59. doi: 10.1016/j.immuni.2016.01.025. Epub 2016 Mar 29.


Close Encounters of the Tertiary Kind.

Lee V, Savage PA.

Immunity. 2015 Sep 15;43(3):418-20. doi: 10.1016/j.immuni.2015.08.022.


Ablation of B7-H3 but Not B7-H4 Results in Highly Increased Tumor Burden in a Murine Model of Spontaneous Prostate Cancer.

Kreymborg K, Haak S, Murali R, Wei J, Waitz R, Gasteiger G, Savage PA, van den Brink MR, Allison JP.

Cancer Immunol Res. 2015 Aug;3(8):849-54. doi: 10.1158/2326-6066.CIR-15-0100. Epub 2015 Jun 29.


Recipient NK cell inactivation and intestinal barrier loss are required for MHC-matched graft-versus-host disease.

Nalle SC, Kwak HA, Edelblum KL, Joseph NE, Singh G, Khramtsova GF, Mortenson ED, Savage PA, Turner JR.

Sci Transl Med. 2014 Jul 2;6(243):243ra87. doi: 10.1126/scitranslmed.3008941.


PD-1 regulates extrathymic regulatory T-cell differentiation.

Chen X, Fosco D, Kline DE, Meng L, Nishi S, Savage PA, Kline J.

Eur J Immunol. 2014 Sep;44(9):2603-16. doi: 10.1002/eji.201344423. Epub 2014 Aug 18.


Shaping the repertoire of tumor-infiltrating effector and regulatory T cells.

Savage PA, Leventhal DS, Malchow S.

Immunol Rev. 2014 May;259(1):245-58. doi: 10.1111/imr.12166. Review.


Tumor antigenicity revealed.

Savage PA.

Trends Immunol. 2014 Feb;35(2):47-8. doi: 10.1016/ Epub 2014 Jan 15.


Organ-specific regulatory T cells of thymic origin are expanded in murine prostate tumors.

Malchow S, Leventhal DS, Savage PA.

Oncoimmunology. 2013 Jul 1;2(7):e24898. Epub 2013 May 7.


Aire-dependent thymic development of tumor-associated regulatory T cells.

Malchow S, Leventhal DS, Nishi S, Fischer BI, Shen L, Paner GP, Amit AS, Kang C, Geddes JE, Allison JP, Socci ND, Savage PA.

Science. 2013 Mar 8;339(6124):1219-24. doi: 10.1126/science.1233913.


Immune reconstitution after combined haploidentical and umbilical cord blood transplant.

Jain N, Liu H, Artz AS, Anastasi J, Odenike O, Godley LA, Joseph L, Marino S, Kline J, Nguyen V, Schouten V, Kunnavakkam R, Larson RA, Stock W, Ulaszek J, Savage PA, Wickrema A, van Besien K.

Leuk Lymphoma. 2013 Jun;54(6):1242-9. doi: 10.3109/10428194.2012.739688. Epub 2013 Mar 1.


Basic principles of tumor-associated regulatory T cell biology.

Savage PA, Malchow S, Leventhal DS.

Trends Immunol. 2013 Jan;34(1):33-40. doi: 10.1016/ Epub 2012 Sep 19. Review.


T cell surveillance of oncogene-induced prostate cancer is impeded by T cell-derived TGF-β1 cytokine.

Donkor MK, Sarkar A, Savage PA, Franklin RA, Johnson LK, Jungbluth AA, Allison JP, Li MO.

Immunity. 2011 Jul 22;35(1):123-34. doi: 10.1016/j.immuni.2011.04.019. Epub 2011 Jul 14.


Effect of resistance training on physical disability in chronic heart failure.

Savage PA, Shaw AO, Miller MS, VanBuren P, LeWinter MM, Ades PA, Toth MJ.

Med Sci Sports Exerc. 2011 Aug;43(8):1379-86. doi: 10.1249/MSS.0b013e31820eeea1.


Recognition of a ubiquitous self antigen by prostate cancer-infiltrating CD8+ T lymphocytes.

Savage PA, Vosseller K, Kang C, Larimore K, Riedel E, Wojnoonski K, Jungbluth AA, Allison JP.

Science. 2008 Jan 11;319(5860):215-20. doi: 10.1126/science.1148886.


A kinetic window constricts the T cell receptor repertoire in the thymus.

Savage PA, Davis MM.

Immunity. 2001 Mar;14(3):243-52.


Visualizing T-cell recognition.

Davis MM, Wülfing C, Krummel MF, Savage PA, Xu J, Sumen C, Dustin ML, Chien YH.

Cold Spring Harb Symp Quant Biol. 1999;64:243-51. Review. No abstract available.


Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients.

Lee PP, Yee C, Savage PA, Fong L, Brockstedt D, Weber JS, Johnson D, Swetter S, Thompson J, Greenberg PD, Roederer M, Davis MM.

Nat Med. 1999 Jun;5(6):677-85.


A kinetic basis for T cell receptor repertoire selection during an immune response.

Savage PA, Boniface JJ, Davis MM.

Immunity. 1999 Apr;10(4):485-92.


Isolation of high avidity melanoma-reactive CTL from heterogeneous populations using peptide-MHC tetramers.

Yee C, Savage PA, Lee PP, Davis MM, Greenberg PD.

J Immunol. 1999 Feb 15;162(4):2227-34.


Peptide chiral purity determination: hydrolysis in deuterated acid, derivatization with Marfey's reagent and analysis using high-performance liquid chromatography-electrospray ionization-mass spectrometry.

Goodlett DR, Abuaf PA, Savage PA, Kowalski KA, Mukherjee TK, Tolan JW, Corkum N, Goldstein G, Crowther JB.

J Chromatogr A. 1995 Jul 21;707(2):233-44.


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