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Items: 15

1.

The purine biosynthesis regulator PurR moonlights as a virulence regulator in Staphylococcus aureus.

Sause WE, Balasubramanian D, Irnov I, Copin R, Sullivan MJ, Sommerfield A, Chan R, Dhabaria A, Askenazi M, Ueberheide B, Shopsin B, van Bakel H, Torres VJ.

Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13563-13572. doi: 10.1073/pnas.1904280116. Epub 2019 Jun 19.

PMID:
31217288
2.

Identification of biologic agents to neutralize the bicomponent leukocidins of Staphylococcus aureus.

Chan R, Buckley PT, O'Malley A, Sause WE, Alonzo F 3rd, Lubkin A, Boguslawski KM, Payne A, Fernandez J, Strohl WR, Whitaker B, Lynch AS, Torres VJ.

Sci Transl Med. 2019 Jan 16;11(475). pii: eaat0882. doi: 10.1126/scitranslmed.aat0882.

PMID:
30651319
3.

Sequential evolution of virulence and resistance during clonal spread of community-acquired methicillin-resistant Staphylococcus aureus.

Copin R, Sause WE, Fulmer Y, Balasubramanian D, Dyzenhaus S, Ahmed JM, Kumar K, Lees J, Stachel A, Fisher JC, Drlica K, Phillips M, Weiser JN, Planet PJ, Uhlemann AC, Altman DR, Sebra R, van Bakel H, Lighter J, Torres VJ, Shopsin B.

Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1745-1754. doi: 10.1073/pnas.1814265116. Epub 2019 Jan 11. Erratum in: Proc Natl Acad Sci U S A. 2019 Feb 25;:.

4.

Genome Plasticity of agr-Defective Staphylococcus aureus during Clinical Infection.

Altman DR, Sullivan MJ, Chacko KI, Balasubramanian D, Pak TR, Sause WE, Kumar K, Sebra R, Deikus G, Attie O, Rose H, Lewis M, Fulmer Y, Bashir A, Kasarskis A, Schadt EE, Richardson AR, Torres VJ, Shopsin B, van Bakel H.

Infect Immun. 2018 Sep 21;86(10). pii: e00331-18. doi: 10.1128/IAI.00331-18. Print 2018 Oct.

5.

Three SpoA-domain proteins interact in the creation of the flagellar type III secretion system in Helicobacter pylori.

Lam KH, Xue C, Sun K, Zhang H, Lam WWL, Zhu Z, Ng JTY, Sause WE, Lertsethtakarn P, Lau KF, Ottemann KM, Au SWN.

J Biol Chem. 2018 Sep 7;293(36):13961-13973. doi: 10.1074/jbc.RA118.002263. Epub 2018 Jul 10.

6.

Human Memory B Cells Targeting Staphylococcus aureus Exotoxins Are Prevalent with Skin and Soft Tissue Infection.

Pelzek AJ, Shopsin B, Radke EE, Tam K, Ueberheide BM, Fenyö D, Brown SM, Li Q, Rubin A, Fulmer Y, Chiang WK, Hernandez DN, El Bannoudi H, Sause WE, Sommerfield A, Thomsen IP, Miller AO, Torres VJ, Silverman GJ.

MBio. 2018 Mar 13;9(2). pii: e02125-17. doi: 10.1128/mBio.02125-17.

7.

Nutritional Regulation of the Sae Two-Component System by CodY in Staphylococcus aureus.

Mlynek KD, Sause WE, Moormeier DE, Sadykov MR, Hill KR, Torres VJ, Bayles KW, Brinsmade SR.

J Bacteriol. 2018 Mar 26;200(8). pii: e00012-18. doi: 10.1128/JB.00012-18. Print 2018 Apr 15.

8.

Staphylococcus aureus Responds to the Central Metabolite Pyruvate To Regulate Virulence.

Harper L, Balasubramanian D, Ohneck EA, Sause WE, Chapman J, Mejia-Sosa B, Lhakhang T, Heguy A, Tsirigos A, Ueberheide B, Boyd JM, Lun DS, Torres VJ.

MBio. 2018 Jan 23;9(1). pii: e02272-17. doi: 10.1128/mBio.02272-17.

9.

Staphylococcus aureus Strain Newman D2C Contains Mutations in Major Regulatory Pathways That Cripple Its Pathogenesis.

Sause WE, Copin R, O'Malley A, Chan R, Morrow BJ, Buckley PT, Fernandez J, Lynch AS, Shopsin B, Torres VJ.

J Bacteriol. 2017 Nov 14;199(24). pii: e00476-17. doi: 10.1128/JB.00476-17. Print 2017 Dec 15.

10.

The Suf Iron-Sulfur Cluster Biosynthetic System Is Essential in Staphylococcus aureus, and Decreased Suf Function Results in Global Metabolic Defects and Reduced Survival in Human Neutrophils.

Roberts CA, Al-Tameemi HM, Mashruwala AA, Rosario-Cruz Z, Chauhan U, Sause WE, Torres VJ, Belden WJ, Boyd JM.

Infect Immun. 2017 May 23;85(6). pii: e00100-17. doi: 10.1128/IAI.00100-17. Print 2017 Jun.

11.

The Helicobacter pylori Autotransporter ImaA Tempers the Bacterium's Interaction with α5β1 Integrin.

Sause WE, Keilberg D, Aboulhouda S, Ottemann KM.

Infect Immun. 2016 Dec 29;85(1). pii: e00450-16. doi: 10.1128/IAI.00450-16. Print 2017 Jan.

12.

Antibody-Based Biologics and Their Promise to Combat Staphylococcus aureus Infections.

Sause WE, Buckley PT, Strohl WR, Lynch AS, Torres VJ.

Trends Pharmacol Sci. 2016 Mar;37(3):231-241. doi: 10.1016/j.tips.2015.11.008. Epub 2015 Dec 22. Review.

13.

Conserved transcriptional unit organization of the cag pathogenicity island among Helicobacter pylori strains.

Ta LH, Hansen LM, Sause WE, Shiva O, Millstein A, Ottemann KM, Castillo AR, Solnick JV.

Front Cell Infect Microbiol. 2012 Apr 20;2:46. doi: 10.3389/fcimb.2012.00046. eCollection 2012.

14.

The Helicobacter pylori autotransporter ImaA (HP0289) modulates the immune response and contributes to host colonization.

Sause WE, Castillo AR, Ottemann KM.

Infect Immun. 2012 Jul;80(7):2286-96. doi: 10.1128/IAI.00312-12. Epub 2012 May 7.

15.

Recombination-based in vivo expression technology identifies Helicobacter pylori genes important for host colonization.

Castillo AR, Woodruff AJ, Connolly LE, Sause WE, Ottemann KM.

Infect Immun. 2008 Dec;76(12):5632-44. doi: 10.1128/IAI.00627-08. Epub 2008 Sep 15. Erratum in: Infect Immun. 2010 Nov;78(11):4967.

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