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Items: 34


Structure and dynamics of G protein-coupled receptor-bound ghrelin reveal the critical role of the octanoyl chain.

Ferré G, Louet M, Saurel O, Delort B, Czaplicki G, M'Kadmi C, Damian M, Renault P, Cantel S, Gavara L, Demange P, Marie J, Fehrentz JA, Floquet N, Milon A, Banères JL.

Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17525-17530. doi: 10.1073/pnas.1905105116. Epub 2019 Aug 15.


Local and Global Dynamics in Klebsiella pneumoniae Outer Membrane Protein a in Lipid Bilayers Probed at Atomic Resolution.

Saurel O, Iordanov I, Nars G, Demange P, Le Marchand T, Andreas LB, Pintacuda G, Milon A.

J Am Chem Soc. 2017 Feb 1;139(4):1590-1597. doi: 10.1021/jacs.6b11565. Epub 2017 Jan 20.


The C-terminal region of the transcriptional regulator THAP11 forms a parallel coiled-coil domain involved in protein dimerization.

Cukier CD, Maveyraud L, Saurel O, Guillet V, Milon A, Gervais V.

J Struct Biol. 2016 Jun;194(3):337-46. doi: 10.1016/j.jsb.2016.03.010. Epub 2016 Mar 11.


The One-carbon Carrier Methylofuran from Methylobacterium extorquens AM1 Contains a Large Number of α- and γ-Linked Glutamic Acid Residues.

Hemmann JL, Saurel O, Ochsner AM, Stodden BK, Kiefer P, Milon A, Vorholt JA.

J Biol Chem. 2016 Apr 22;291(17):9042-51. doi: 10.1074/jbc.M116.714741. Epub 2016 Feb 19.


Combined experimental and simulation studies suggest a revised mode of action of the anti-Alzheimer disease drug NQ-Trp.

Berthoumieu O, Nguyen PH, Castillo-Frias MP, Ferre S, Tarus B, Nasica-Labouze J, Noël S, Saurel O, Rampon C, Doig AJ, Derreumaux P, Faller P.

Chemistry. 2015 Sep 1;21(36):12657-66. doi: 10.1002/chem.201500888. Epub 2015 Jul 14.


Two classes of cholesterol binding sites for the β2AR revealed by thermostability and NMR.

Gater DL, Saurel O, Iordanov I, Liu W, Cherezov V, Milon A.

Biophys J. 2014 Nov 18;107(10):2305-12. doi: 10.1016/j.bpj.2014.10.011.


Production of stable isotope labelled lipase Lip2 from Yarrowia lipolytica for NMR: investigation of several expression systems.

Nars G, Saurel O, Bordes F, Saves I, Remaud-Siméon M, André I, Milon A, Marty A.

Protein Expr Purif. 2014 Sep;101:14-20. doi: 10.1016/j.pep.2014.05.007. Epub 2014 May 21.


Mutation of a pH-modulating residue in a GH51 α-l-arabinofuranosidase leads to a severe reduction of the secondary hydrolysis of transfuranosylation products.

Bissaro B, Saurel O, Arab-Jaziri F, Saulnier L, Milon A, Tenkanen M, Monsan P, O'Donohue MJ, Fauré R.

Biochim Biophys Acta. 2014 Jan;1840(1):626-36. doi: 10.1016/j.bbagen.2013.10.013. Epub 2013 Oct 17.


NMR localization of the O-mycoloylation on PorH, a channel forming peptide from Corynebacterium glutamicum.

Rath P, Saurel O, Tropis M, Daffé M, Demange P, Milon A.

FEBS Lett. 2013 Nov 15;587(22):3687-91. doi: 10.1016/j.febslet.2013.09.032. Epub 2013 Oct 4.


Hydrogen bonding of cholesterol in the lipidic cubic phase.

Gater DL, Réat V, Czaplicki G, Saurel O, Milon A, Jolibois F, Cherezov V.

Langmuir. 2013 Jun 25;29(25):8031-8. doi: 10.1021/la401351w. Epub 2013 Jun 13.


Cord factor (trehalose 6,6'-dimycolate) forms fully stable and non-permeable lipid bilayers required for a functional outer membrane.

Rath P, Saurel O, Czaplicki G, Tropis M, Daffé M, Ghazi A, Demange P, Milon A.

Biochim Biophys Acta. 2013 Sep;1828(9):2173-81. doi: 10.1016/j.bbamem.2013.04.021. Epub 2013 May 1.


Engineering transglycosidase activity into a GH51 α-l-arabinofuranosidase.

Arab-Jaziri F, Bissaro B, Dion M, Saurel O, Harrison D, Ferreira F, Milon A, Tellier C, Fauré R, O'Donohue MJ.

N Biotechnol. 2013 Jun 25;30(5):536-44. doi: 10.1016/j.nbt.2013.04.002. Epub 2013 Apr 27.


Functional roles of H98 and W99 and β2α2 loop dynamics in the α-l-arabinofuranosidase from Thermobacillus xylanilyticus.

Arab-Jaziri F, Bissaro B, Barbe S, Saurel O, Débat H, Dumon C, Gervais V, Milon A, André I, Fauré R, O'Donohue MJ.

FEBS J. 2012 Oct;279(19):3598-3611. doi: 10.1111/j.1742-4658.2012.08720.x. Epub 2012 Aug 31.


Dynamics of Klebsiella pneumoniae OmpA transmembrane domain: the four extracellular loops display restricted motion behavior in micelles and in lipid bilayers.

Iordanov I, Renault M, Réat V, Bosshart PD, Engel A, Saurel O, Milon A.

Biochim Biophys Acta. 2012 Sep;1818(9):2344-53. doi: 10.1016/j.bbamem.2012.05.004. Epub 2012 May 9.


Functional expression of the PorAH channel from Corynebacterium glutamicum in cell-free expression systems: implications for the role of the naturally occurring mycolic acid modification.

Rath P, Demange P, Saurel O, Tropis M, Daffé M, Dötsch V, Ghazi A, Bernhard F, Milon A.

J Biol Chem. 2011 Sep 16;286(37):32525-32. doi: 10.1074/jbc.M111.276956. Epub 2011 Jul 28.


NMR-based structural glycomics for high-throughput screening of carbohydrate-active enzyme specificity.

Irague R, Massou S, Moulis C, Saurel O, Milon A, Monsan P, Remaud-Siméon M, Portais JC, Potocki-Véronèse G.

Anal Chem. 2011 Feb 15;83(4):1202-6. doi: 10.1021/ac1032148. Epub 2011 Jan 27.


Solution-state NMR spectroscopy of membrane proteins in detergent micelles: structure of the Klebsiella pneumoniae outer membrane protein A, KpOmpA.

Renault M, Saurel O, Demange P, Reat V, Milon A.

Methods Mol Biol. 2010;654:321-39. doi: 10.1007/978-1-60761-762-4_17.


Order parameters of a transmembrane helix in a fluid bilayer: case study of a WALP peptide.

Holt A, Rougier L, Réat V, Jolibois F, Saurel O, Czaplicki J, Killian JA, Milon A.

Biophys J. 2010 May 19;98(9):1864-72. doi: 10.1016/j.bpj.2010.01.016.


Structural determinants of specific DNA-recognition by the THAP zinc finger.

Campagne S, Saurel O, Gervais V, Milon A.

Nucleic Acids Res. 2010 Jun;38(10):3466-76. doi: 10.1093/nar/gkq053. Epub 2010 Feb 9.


GATEWAY technology and E. coli recombinant system produce a properly folded and functional recombinant allergen of the lipid transfer protein of apple (Mal d 3).

Borges JP, Culerrier R, Aldon D, Barre A, Benoist H, Saurel O, Milon A, Didier A, Rougé P.

Protein Expr Purif. 2010 Apr;70(2):277-82. doi: 10.1016/j.pep.2009.09.009. Epub 2009 Sep 22.


Study of the specific lipid binding properties of Abeta 11-22 fragment at endosomal pH.

Ravault S, Flore C, Saurel O, Milon A, Brasseur R, Lins L.

Langmuir. 2009 Sep 15;25(18):10948-53. doi: 10.1021/la901544g.


Solution state NMR structure and dynamics of KpOmpA, a 210 residue transmembrane domain possessing a high potential for immunological applications.

Renault M, Saurel O, Czaplicki J, Demange P, Gervais V, Löhr F, Réat V, Piotto M, Milon A.

J Mol Biol. 2009 Jan 9;385(1):117-30. doi: 10.1016/j.jmb.2008.10.021. Epub 2008 Oct 15.


Structural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: towards the design of higher-affinity inhibitors.

Hazan C, Boudsocq F, Gervais V, Saurel O, Ciais M, Cazaux C, Czaplicki J, Milon A.

BMC Struct Biol. 2008 Apr 16;8:22. doi: 10.1186/1472-6807-8-22.


The Ralstonia solanacearum pathogenicity regulator HrpB induces 3-hydroxy-oxindole synthesis.

Delaspre F, Nieto Peñalver CG, Saurel O, Kiefer P, Gras E, Milon A, Boucher C, Genin S, Vorholt JA.

Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15870-5. Epub 2007 Sep 21.


Methylobacterium extorquens AM1 produces a novel type of acyl-homoserine lactone with a double unsaturated side chain under methylotrophic growth conditions.

Nieto Penalver CG, Morin D, Cantet F, Saurel O, Milon A, Vorholt JA.

FEBS Lett. 2006 Jan 23;580(2):561-7. Epub 2005 Dec 28.


15N T2' relaxation times of bacteriorhodopsin transmembrane amide nitrogens.

Soubias O, Réat V, Saurel O, Milon A.

Magn Reson Chem. 2004 Feb;42(2):212-7.


High resolution 2D 1H-13C correlation of cholesterol in model membrane.

Soubias O, Réat V, Saurel O, Milon A.

J Magn Reson. 2002 Sep-Oct;158(1-2):143-8.


Generation of formate by the formyltransferase/hydrolase complex (Fhc) from Methylobacterium extorquens AM1.

Pomper BK, Saurel O, Milon A, Vorholt JA.

FEBS Lett. 2002 Jul 17;523(1-3):133-7.


Organization and dynamics of the proteolipid complexes formed by annexin V and lipids in planar supported lipid bilayers.

Cézanne L, Lopez A, Loste F, Parnaud G, Saurel O, Demange P, Tocanne JF.

Biochemistry. 1999 Mar 2;38(9):2779-86.


Influence of annexin V on the structure and dynamics of phosphatidylcholine/phosphatidylserine bilayers: a fluorescence and NMR study.

Saurel O, Cézanne L, Milon A, Tocanne JF, Demange P.

Biochemistry. 1998 Feb 3;37(5):1403-10.


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